Ligand ID: DEX

Drugbank ID:
Dexamethasone
(DB01234)

Indication:
Dexamethasone is a glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.

LIST OF BINDING INTERFACES for query 'DB01234'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
3MNP_A_DEXA784	3mnp	DEX	Dexamethasone (DB01234)	Mus musculus; synthetic construct	GLUCOCORTICOID RECEPTOR	Hormone_recep	22	MET A 566 LEU A 569 ASN A 570 LEU A 572 GLY A 573 GLN A 576 TRP A 606 MET A 607 MET A 610 VAL A 611 LEU A 614 ARG A 617 PHE A 629 GLN A 648 MET A 652 LEU A 738 TYR A 741 CYS A 742 THR A 745 ILE A 753 PHE A 755 LEU A 759	DEX A 784		Details
4UDA_A_DEXA1985	4uda	DEX	Dexamethasone (DB01234)	Homo sapiens	MINERALOCORTICOID RECEPTOR	Hormone_recep	23	LEU A 766 LEU A 769 ASN A 770 LEU A 772 ALA A 773 GLN A 776 TRP A 806 MET A 807 SER A 810 SER A 811 LEU A 814 ARG A 817 PHE A 829 MET A 845 LEU A 848 MET A 852 LEU A 938 PHE A 941 CYS A 942 THR A 945 VAL A 954 PHE A 956 LEU A 960	DEX A1985		Details
6NWK_A_DEXA301	6nwk	DEX	Dexamethasone (DB01234)	Homo sapiens; synthetic construct	GLUCOCORTICOID RECEPTOR	NA	22	MET A  29 LEU A  32 ASN A  33 LEU A  35 GLY A  36 GLN A  39 TRP A  69 MET A  70 MET A  73 ALA A  74 LEU A  77 ARG A  80 PHE A  92 GLN A 111 MET A 115 LEU A 201 PHE A 204 CYS A 205 THR A 208 VAL A 216 PHE A 218 LEU A 222	DEX A 301		Details
6XK0_A_DEXA601	6xk0	DEX	Dexamethasone (DB01234)	Equus caballus	ALBUMIN	Serum_albumin	13	ARG A 208 LYS A 211 ALA A 212 VAL A 215 ASP A 323 LEU A 326 GLY A 327 LEU A 330 LEU A 346 ALA A 349 LYS A 350 GLU A 353 ALA A 481	DEX A 601		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["3MNP_A_DEXA784","3mnp","DEX","Dexamethasone (DB01234)","Mus musculus;synthetic construct","GLUCOCORTICOID RECEPTOR","Hormone_recep",22,"MET A 566;LEU A 569;ASN A 570;LEU A 572;GLY A 573;GLN A 576;TRP A 606;MET A 607;MET A 610;VAL A 611;LEU A 614;ARG A 617;PHE A 629;GLN A 648;MET A 652;LEU A 738;TYR A 741;CYS A 742;THR A 745;ILE A 753;PHE A 755;LEU A 759","DEX A 784\r"],["4UDA_A_DEXA1985","4uda","DEX","Dexamethasone (DB01234)","Homo sapiens","MINERALOCORTICOID RECEPTOR","Hormone_recep",23,"LEU A 766;LEU A 769;ASN A 770;LEU A 772;ALA A 773;GLN A 776;TRP A 806;MET A 807;SER A 810;SER A 811;LEU A 814;ARG A 817;PHE A 829;MET A 845;LEU A 848;MET A 852;LEU A 938;PHE A 941;CYS A 942;THR A 945;VAL A 954;PHE A 956;LEU A 960","DEX A1985\r"],["6NWK_A_DEXA301","6nwk","DEX","Dexamethasone (DB01234)","Homo sapiens;synthetic construct","GLUCOCORTICOID RECEPTOR","NA",22,"MET A 29;LEU A 32;ASN A 33;LEU A 35;GLY A 36;GLN A 39;TRP A 69;MET A 70;MET A 73;ALA A 74;LEU A 77;ARG A 80;PHE A 92;GLN A 111;MET A 115;LEU A 201;PHE A 204;CYS A 205;THR A 208;VAL A 216;PHE A 218;LEU A 222","DEX A 301\r"],["6XK0_A_DEXA601","6xk0","DEX","Dexamethasone (DB01234)","Equus caballus","ALBUMIN","Serum_albumin",13,"ARG A 208;LYS A 211;ALA A 212;VAL A 215;ASP A 323;LEU A 326;GLY A 327;LEU A 330;LEU A 346;ALA A 349;LYS A 350;GLU A 353;ALA A 481","DEX A 601\r"]]