Ligand ID: 377

Drugbank ID:
Memantine
(DB01043)

Indication:
Memantine is an NMDA receptor antagonist used to treat moderate to severe dementia in Alzheimer's.


LIST OF BINDING INTERFACES for query 'DB01043'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details
4TWD_A_377A4014twd 377Memantine
(DB01043) 		Dickeya chrysanthemi CYS-LOOP LIGAND-GATED ION CHANNEL NA 11TYR E  38
GLU A  77
ILE A  79
ARG E  91
ASN E 103
GLU A 131
PRO A 132
PHE A 133
TYR A 175
LEU A 178
PHE A 188
377 A 401
4TWD_A_377A4024twd 377Memantine
(DB01043) 		Dickeya chrysanthemi CYS-LOOP LIGAND-GATED ION CHANNEL NA 11LEU E 240
ALA D 244
ALA C 244
ALA B 244
ALA E 244
ALA A 244
SER B 247
SER E 247
SER A 247
SER C 247
SER D 247
377 A 402
DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details