Results: Ligand

Ligand ID: DM2

Drugbank ID:
Doxorubicin
(DB00997)

Indication:
Doxorubicin is a medication used to treat various cancers and Kaposi's Sarcoma.

LIST OF BINDING INTERFACES for query 'DB00997'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1I1E_A_DM2A3001	1i1e	DM2	Doxorubicin (DB00997)	Clostridium botulinum	BOTULINUM NEUROTOXIN TYPE B	Peptidase_M27 Toxin_R_bind_C Toxin_R_bind_N Toxin_trans	14	GLU A1188 GLU A1189 LEU A1236 ILE A1237 GLY A1238 ILE A1239 HIS A1240 ARG A1241 ASP A1254 CYS A1257 ILE A1258 SER A1259 TRP A1261 TYR A1262	DM2 A3001
4DX7_A_DM2A1105	4dx7	DM2	Doxorubicin (DB00997)	Escherichia coli; synthetic construct	ACRIFLAVINE RESISTANCE PROTEIN B	ACR_tran	17	MET A 575 GLN A 577 GLY A 616 PHE A 617 ALA A 618 THR A 624 THR A 676 GLY A 679 ASP A 681 ARG A 717 ASN A 719 ARG A 815 GLU A 826 LEU A 828 GLY A 829 GLN A 830 MET A 862	DM2 A1105
4DX7_A_DM2A1106	4dx7	DM2	Doxorubicin (DB00997)	Escherichia coli; synthetic construct	ACRIFLAVINE RESISTANCE PROTEIN B	ACR_tran	16	SER A 134 ASP A 566 MET A 575 PHE A 617 PHE A 664 ALA A 665 PHE A 666 ASN A 667 LEU A 668 PRO A 669 VAL A 672 THR A 676 ALA A 677 SER A 715 ARG A 717 GLN A 830	DM2 A1106
4ZVM_A_DM2A303	4zvm	DM2	Doxorubicin (DB00997)	Homo sapiens	RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]	Flavodoxin_2	20	VAL B 69 HIS B 72 TRP A 105 PHE A 106 GLN B 122 PHE B 126 ILE B 128 PHE B 131 TYR B 132 GLY A 149 GLY A 150 THR A 151 MET A 154 TYR A 155 ASN A 161 GLY B 174 PHE B 178 ALA A 191 GLU A 193 ILE A 194	DM2 A 303
5MRA_B_DM2B204	5mra	DM2	Doxorubicin (DB00997)	Homo sapiens	SORCIN	EF-hand_6 EF-hand_8	8	PHE B 134 THR B 170 ARG B 174 ASP B 177 GLN B 180 GLN B 181 GLY B 182 TYR A 188	DM2 B 204
5OM7_A_DM2A501	5om7	DM2	Doxorubicin (DB00997)	Homo sapiens	ALPHA-1-ANTICHYMOTRYPSIN	NA	13	VAL A 31 GLN A 242 ASN A 244 GLN A 270 LEU A 273 SER A 274 PHE A 277 GLU A 278 LEU A 280 VAL B 381 ASP B 382 ASN B 383 TRP B 386	DM2 A 501
6FTP_B_DM2B501	6ftp	DM2	Doxorubicin (DB00997)	Homo sapiens	ALPHA-1-ANTICHYMOTRYPSIN	NA	14	VAL A 31 GLN A 242 TYR A 245 SER A 250 GLN A 270 LEU A 273 SER A 274 PHE A 277 GLU A 278 LEU A 280 VAL B 381 ASP B 382 ASN B 383 TRP B 386	DM2 B 501
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1I1E_A_DM2A3001","1i1e","DM2","Doxorubicin (DB00997)","Clostridium botulinum","BOTULINUM NEUROTOXIN TYPE B","Peptidase_M27;Toxin_R_bind_C;Toxin_R_bind_N;Toxin_trans",14,"GLU A1188;GLU A1189;LEU A1236;ILE A1237;GLY A1238;ILE A1239;HIS A1240;ARG A1241;ASP A1254;CYS A1257;ILE A1258;SER A1259;TRP A1261;TYR A1262","DM2 A3001\r"],["4DX7_A_DM2A1105","4dx7","DM2","Doxorubicin (DB00997)","Escherichia coli;synthetic construct","ACRIFLAVINE RESISTANCE PROTEIN B","ACR_tran",17,"MET A 575;GLN A 577;GLY A 616;PHE A 617;ALA A 618;THR A 624;THR A 676;GLY A 679;ASP A 681;ARG A 717;ASN A 719;ARG A 815;GLU A 826;LEU A 828;GLY A 829;GLN A 830;MET A 862","DM2 A1105\r"],["4DX7_A_DM2A1106","4dx7","DM2","Doxorubicin (DB00997)","Escherichia coli;synthetic construct","ACRIFLAVINE RESISTANCE PROTEIN B","ACR_tran",16,"SER A 134;ASP A 566;MET A 575;PHE A 617;PHE A 664;ALA A 665;PHE A 666;ASN A 667;LEU A 668;PRO A 669;VAL A 672;THR A 676;ALA A 677;SER A 715;ARG A 717;GLN A 830","DM2 A1106\r"],["4ZVM_A_DM2A303","4zvm","DM2","Doxorubicin (DB00997)","Homo sapiens","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","Flavodoxin_2",20,"VAL B  69;HIS B  72;TRP A 105;PHE A 106;GLN B 122;PHE B 126;ILE B 128;PHE B 131;TYR B 132;GLY A 149;GLY A 150;THR A 151;MET A 154;TYR A 155;ASN A 161;GLY B 174;PHE B 178;ALA A 191;GLU A 193;ILE A 194","DM2 A 303\r"],["5MRA_B_DM2B204","5mra","DM2","Doxorubicin (DB00997)","Homo sapiens","SORCIN","EF-hand_6;EF-hand_8",8,"PHE B 134;THR B 170;ARG B 174;ASP B 177;GLN B 180;GLN B 181;GLY B 182;TYR A 188","DM2 B 204\r"],["5OM7_A_DM2A501","5om7","DM2","Doxorubicin (DB00997)","Homo sapiens","ALPHA-1-ANTICHYMOTRYPSIN","NA",13,"VAL A  31;GLN A 242;ASN A 244;GLN A 270;LEU A 273;SER A 274;PHE A 277;GLU A 278;LEU A 280;VAL B 381;ASP B 382;ASN B 383;TRP B 386","DM2 A 501\r"],["6FTP_B_DM2B501","6ftp","DM2","Doxorubicin (DB00997)","Homo sapiens","ALPHA-1-ANTICHYMOTRYPSIN","NA",14,"VAL A  31;GLN A 242;TYR A 245;SER A 250;GLN A 270;LEU A 273;SER A 274;PHE A 277;GLU A 278;LEU A 280;VAL B 381;ASP B 382;ASN B 383;TRP B 386","DM2 B 501\r"]]