Ligand ID: CWB

Drugbank ID:
Granisetron
(DB00889)

Indication:
Granisetron is a 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively.

LIST OF BINDING INTERFACES for query 'DB00889'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2YME_A_CWBA1207	2yme	CWB	Granisetron (DB00889)	Aplysia californica	SOLUBLE ACETYLCHOLINE RECEPTOR	NA	13	THR B  34 TRP B  53 ARG B  55 TYR A  91 MET B 114 ILE B 116 SER A 144 TRP A 145 ASP B 162 TYR A 186 CYS A 188 CYS A 189 TYR A 193	CWB A1207		Details
6NP0_A_CWBA508	6np0	CWB	Granisetron (DB00889)	Mus musculus	5-HYDROXYTRYPTAMINE RECEPTOR 3A	Neur_chan_LBD Neur_chan_memb	15	ASP E  42 VAL E  43 ILE E  44 TRP E  63 TYR E  64 ARG E  65 ASN A 101 TYR E 126 THR A 154 SER A 155 TRP A 156 ARG E 169 PHE A 199 ILE A 201 TYR A 207	CWB A 508		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2YME_A_CWBA1207","2yme","CWB","Granisetron (DB00889)","Aplysia californica","SOLUBLE ACETYLCHOLINE RECEPTOR","NA",13,"THR B 34;TRP B 53;ARG B 55;TYR A 91;MET B 114;ILE B 116;SER A 144;TRP A 145;ASP B 162;TYR A 186;CYS A 188;CYS A 189;TYR A 193","CWB A1207\r"],["6NP0_A_CWBA508","6np0","CWB","Granisetron (DB00889)","Mus musculus","5-HYDROXYTRYPTAMINE RECEPTOR 3A","Neur_chan_LBD;Neur_chan_memb",15,"ASP E 42;VAL E 43;ILE E 44;TRP E 63;TYR E 64;ARG E 65;ASN A 101;TYR E 126;THR A 154;SER A 155;TRP A 156;ARG E 169;PHE A 199;ILE A 201;TYR A 207","CWB A 508\r"]]