Results: Ligand

Ligand ID: VDN

Drugbank ID:
Vardenafil
(DB00862)

Indication:
Vardenafil is a phosphodiesterase 5 inhibitor used to treat erectile dysfunction.

LIST OF BINDING INTERFACES for query 'DB00862'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1XOT_B_VDNB102	1xot	VDN	Vardenafil (DB00862)	Homo sapiens	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B	PDEase_I	15	TYR B 233 HIS B 234 MET B 347 ASP B 392 LEU B 393 ASN B 395 ILE B 410 MET B 411 PHE B 414 SER B 429 MET B 431 CYS B 432 SER B 442 GLN B 443 PHE B 446	VDN B 102
1XP0_A_VDNA201	1xp0	VDN	Vardenafil (DB00862)	Homo sapiens	CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE	PDEase_I	17	TYR A 612 HIS A 613 LEU A 725 LEU A 765 ALA A 767 ILE A 768 GLN A 775 ALA A 779 VAL A 782 ALA A 783 PHE A 786 LEU A 804 ILE A 813 MET A 816 GLN A 817 PHE A 820 ILE A 824	VDN A 201
7JSN_A_VDNA904	7jsn	VDN	Vardenafil (DB00862)	Bos taurus	ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA	GAF PDEase_I	13	TYR A 558 LEU A 671 LEU A 721 ALA A 723 ALA A 735 VAL A 738 ALA A 739 PHE A 742 MET A 760 LEU A 769 LEU A 772 GLN A 773 PHE A 776	VDN A 904
7JSN_B_VDNB904	7jsn	VDN	Vardenafil (DB00862)	Bos taurus	ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT BETA	GAF PDEase_I	13	TYR B 556 LEU B 669 ALA B 721 ILE B 722 ALA B 733 VAL B 736 ALA B 737 PHE B 740 MET B 758 LEU B 767 LEU B 770 GLN B 771 PHE B 774	VDN B 904
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1XOT_B_VDNB102","1xot","VDN","Vardenafil (DB00862)","Homo sapiens","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B","PDEase_I",15,"TYR B 233;HIS B 234;MET B 347;ASP B 392;LEU B 393;ASN B 395;ILE B 410;MET B 411;PHE B 414;SER B 429;MET B 431;CYS B 432;SER B 442;GLN B 443;PHE B 446","VDN B 102\r"],["1XP0_A_VDNA201","1xp0","VDN","Vardenafil (DB00862)","Homo sapiens","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","PDEase_I",17,"TYR A 612;HIS A 613;LEU A 725;LEU A 765;ALA A 767;ILE A 768;GLN A 775;ALA A 779;VAL A 782;ALA A 783;PHE A 786;LEU A 804;ILE A 813;MET A 816;GLN A 817;PHE A 820;ILE A 824","VDN A 201\r"],["7JSN_A_VDNA904","7jsn","VDN","Vardenafil (DB00862)","Bos taurus","ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA","GAF;PDEase_I",13,"TYR A 558;LEU A 671;LEU A 721;ALA A 723;ALA A 735;VAL A 738;ALA A 739;PHE A 742;MET A 760;LEU A 769;LEU A 772;GLN A 773;PHE A 776","VDN A 904\r"],["7JSN_B_VDNB904","7jsn","VDN","Vardenafil (DB00862)","Bos taurus","ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT BETA","GAF;PDEase_I",13,"TYR B 556;LEU B 669;ALA B 721;ILE B 722;ALA B 733;VAL B 736;ALA B 737;PHE B 740;MET B 758;LEU B 767;LEU B 770;GLN B 771;PHE B 774","VDN B 904\r"]]