Ligand ID: HCY

Drugbank ID:
Hydrocortisone
(DB00741)

Indication:
Hydrocortisone is a glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.

LIST OF BINDING INTERFACES for query 'DB00741'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2V95_A_HCYA1375	2v95	HCY	Hydrocortisone (DB00741)	Rattus norvegicus	CORTICOSTEROID-BINDING GLOBULIN	Serpin	13	ALA A  13 PRO A  14 VAL A  17 GLN A 224 THR A 232 PHE A 234 ARG A 252 ILE A 255 ASP A 256 GLY A 259 PHE A 357 LYS A 359 TRP A 362	HCY A1375		Details
2VDY_A_HCYA1384	2vdy	HCY	Hydrocortisone (DB00741)	Homo sapiens	CORTICOSTEROID-BINDING GLOBULIN	Serpin	13	ALA A  18 SER A  19 VAL A  22 GLN A 232 THR A 240 PHE A 242 ARG A 260 ILE A 263 ASN A 264 SER A 267 PHE A 366 HIS A 368 TRP A 371	HCY A1384		Details
4P6X_A_HCYA900	4p6x	HCY	Hydrocortisone (DB00741)	Homo sapiens; synthetic construct	GLUCOCORTICOID RECEPTOR	Hormone_recep	22	MET A 560 LEU A 563 ASN A 564 LEU A 566 GLY A 567 GLN A 570 TRP A 600 MET A 601 MET A 604 ALA A 605 LEU A 608 ARG A 611 PHE A 623 GLN A 642 MET A 646 LEU A 732 TYR A 735 CYS A 736 THR A 739 ILE A 747 PHE A 749 LEU A 753	HCY A 900		Details
5HGC_A_HCYA501	5hgc	HCY	Hydrocortisone (DB00741)	Taeniopygia guttata	SERPIN	NA	14	VAL A  32 PRO A  33 ALA A  36 ARG A 246 THR A 254 PHE A 256 LYS A 274 ILE A 277 GLN A 278 SER A 281 PHE A 380 ASP A 381 ARG A 382 ASN A 385	HCY A 501		Details
6HGF_B_HCYB501	6hgf	HCY	Hydrocortisone (DB00741)	Homo sapiens	ALPHA-1-ANTICHYMOTRYPSIN	NA	14	ARG A  24 ALA A  27 SER A  28 VAL A  31 GLN A 242 LEU A 252 ARG A 270 LEU A 273 ALA A 274 GLY A 277 LEU A 280 VAL B 381 HIS B 383 TRP B 386	HCY B 501		Details
6HGG_A_HCYA401	6hgg	HCY	Hydrocortisone (DB00741)	Homo sapiens	ALPHA-1-ANTICHYMOTRYPSIN	NA	13	ARG A  24 ALA A  27 SER A  28 VAL A  31 GLN A 242 PHE A 252 ARG A 270 LEU A 273 ALA A 274 GLY A 277 VAL B 381 HIS B 383 TRP B 386	HCY A 401		Details
6ITQ_A_HCYA201	6itq	HCY	Hydrocortisone (DB00741)	Camelus bactrianus	ANTI-CORTISOL CAMELID ANTIBODY	NA	15	VAL A  24 THR A  28 GLY A  29 SER A  30 THR A  31 GLY A  32 TYR A  33 TRP A  34 THR A  53 GLN A  75 ASN A  77 LYS A  80 SER A 101 THR A 102 ARG A 103	HCY A 201		Details
6NWL_A_HCYA301	6nwl	HCY	Hydrocortisone (DB00741)	Homo sapiens; synthetic construct	GLUCOCORTICOID RECEPTOR	NA	22	MET A  29 LEU A  32 ASN A  33 LEU A  35 GLY A  36 GLN A  39 TRP A  69 MET A  70 MET A  73 ALA A  74 LEU A  77 ARG A  80 PHE A  92 GLN A 111 MET A 115 LEU A 201 PHE A 204 CYS A 205 THR A 208 VAL A 216 PHE A 218 LEU A 222	HCY A 301		Details
7D77_R_HCYR604	7d77	HCY	Hydrocortisone (DB00741)	Homo sapiens; synthetic construct	ADHESION G PROTEIN-COUPLED RECEPTOR G3; GPR97	NA	13	LEU R 319 ASN R 320 PHE R 323 PHE R 345 LEU R 349 ILE R 408 LEU R 419 TRP R 421 TRP R 490 ALA R 493 ILE R 494 LEU R 498 ASN R 510	HCY R 604		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2V95_A_HCYA1375","2v95","HCY","Hydrocortisone (DB00741)","Rattus norvegicus","CORTICOSTEROID-BINDING GLOBULIN","Serpin",13,"ALA A 13;PRO A 14;VAL A 17;GLN A 224;THR A 232;PHE A 234;ARG A 252;ILE A 255;ASP A 256;GLY A 259;PHE A 357;LYS A 359;TRP A 362","HCY A1375\r"],["2VDY_A_HCYA1384","2vdy","HCY","Hydrocortisone (DB00741)","Homo sapiens","CORTICOSTEROID-BINDING GLOBULIN","Serpin",13,"ALA A 18;SER A 19;VAL A 22;GLN A 232;THR A 240;PHE A 242;ARG A 260;ILE A 263;ASN A 264;SER A 267;PHE A 366;HIS A 368;TRP A 371","HCY A1384\r"],["4P6X_A_HCYA900","4p6x","HCY","Hydrocortisone (DB00741)","Homo sapiens;synthetic construct","GLUCOCORTICOID RECEPTOR","Hormone_recep",22,"MET A 560;LEU A 563;ASN A 564;LEU A 566;GLY A 567;GLN A 570;TRP A 600;MET A 601;MET A 604;ALA A 605;LEU A 608;ARG A 611;PHE A 623;GLN A 642;MET A 646;LEU A 732;TYR A 735;CYS A 736;THR A 739;ILE A 747;PHE A 749;LEU A 753","HCY A 900\r"],["5HGC_A_HCYA501","5hgc","HCY","Hydrocortisone (DB00741)","Taeniopygia guttata","SERPIN","NA",14,"VAL A 32;PRO A 33;ALA A 36;ARG A 246;THR A 254;PHE A 256;LYS A 274;ILE A 277;GLN A 278;SER A 281;PHE A 380;ASP A 381;ARG A 382;ASN A 385","HCY A 501\r"],["6HGF_B_HCYB501","6hgf","HCY","Hydrocortisone (DB00741)","Homo sapiens","ALPHA-1-ANTICHYMOTRYPSIN","NA",14,"ARG A 24;ALA A 27;SER A 28;VAL A 31;GLN A 242;LEU A 252;ARG A 270;LEU A 273;ALA A 274;GLY A 277;LEU A 280;VAL B 381;HIS B 383;TRP B 386","HCY B 501\r"],["6HGG_A_HCYA401","6hgg","HCY","Hydrocortisone (DB00741)","Homo sapiens","ALPHA-1-ANTICHYMOTRYPSIN","NA",13,"ARG A 24;ALA A 27;SER A 28;VAL A 31;GLN A 242;PHE A 252;ARG A 270;LEU A 273;ALA A 274;GLY A 277;VAL B 381;HIS B 383;TRP B 386","HCY A 401\r"],["6ITQ_A_HCYA201","6itq","HCY","Hydrocortisone (DB00741)","Camelus bactrianus","ANTI-CORTISOL CAMELID ANTIBODY","NA",15,"VAL A 24;THR A 28;GLY A 29;SER A 30;THR A 31;GLY A 32;TYR A 33;TRP A 34;THR A 53;GLN A 75;ASN A 77;LYS A 80;SER A 101;THR A 102;ARG A 103","HCY A 201\r"],["6NWL_A_HCYA301","6nwl","HCY","Hydrocortisone (DB00741)","Homo sapiens;synthetic construct","GLUCOCORTICOID RECEPTOR","NA",22,"MET A 29;LEU A 32;ASN A 33;LEU A 35;GLY A 36;GLN A 39;TRP A 69;MET A 70;MET A 73;ALA A 74;LEU A 77;ARG A 80;PHE A 92;GLN A 111;MET A 115;LEU A 201;PHE A 204;CYS A 205;THR A 208;VAL A 216;PHE A 218;LEU A 222","HCY A 301\r"],["7D77_R_HCYR604","7d77","HCY","Hydrocortisone (DB00741)","Homo sapiens;synthetic construct","ADHESION G PROTEIN-COUPLED RECEPTOR G3; GPR97","NA",13,"LEU R 319;ASN R 320;PHE R 323;PHE R 345;LEU R 349;ILE R 408;LEU R 419;TRP R 421;TRP R 490;ALA R 493;ILE R 494;LEU R 498;ASN R 510","HCY R 604\r"]]