Ligand ID: 6T0

Drugbank ID:
Imiquimod
(DB00724)

Indication:
Imiquimod is a toll-like receptor 7 agonist used to treat non hyperkeratotic, non hypertrophic actinic keratosis, basal cell carcinoma, genital or perianal warts, and condyloma acuminata.


LIST OF BINDING INTERFACES for query 'DB00724'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details
5LBT_A_6T0A3035lbt 6T0Imiquimod
(DB00724) 		Homo sapiens RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE] Flavodoxin_2 13TRP B 105
PHE B 106
PHE A 126
ILE A 128
PHE A 131
GLY B 149
GLY B 150
MET B 154
TYR B 155
ASN B 161
GLY A 174
PHE A 178
GLU B 193
6T0 A 303
5LBT_A_6T0A3045lbt 6T0Imiquimod
(DB00724) 		Homo sapiens RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE] Flavodoxin_2 13GLY B  68
TRP A 105
PHE A 106
PHE B 126
ILE B 128
TYR B 132
GLY A 149
GLY A 150
MET A 154
TYR A 155
ASN A 161
PHE B 178
GLU A 193
6T0 A 304
5ZSF_B_6T0B9135zsf 6T0Imiquimod
(DB00724) 		Macaca mulatta TOLL-LIKE RECEPTOR 7 LRR_5
LRR_8 		13PHE A 351
GLN A 354
VAL A 355
TYR A 356
VAL A 381
PHE A 408
LYS A 432
THR B 532
ASP B 555
LEU B 557
GLY B 584
ILE B 585
THR B 586
6T0 B 913
DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details