Results: Ligand

Ligand ID: CTX

Drugbank ID:
Tamoxifen
(DB00675)

Indication:
Tamoxifen is a selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women.

LIST OF BINDING INTERFACES for query 'DB00675'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1YA4_A_CTXA11	1ya4	CTX	Tamoxifen (DB00675)	Homo sapiens	CES1 PROTEIN	COesterase	11	GLY A 356 TRP A 357 PRO A 360 MET A 361 TYR A 366 LEU A 368 SER A 369 GLY A 371 LYS A 414 LEU A 418 PRO A 461	CTX A 11
1YA4_A_CTXA1	1ya4	CTX	Tamoxifen (DB00675)	Homo sapiens	CES1 PROTEIN	COesterase	20	ALA A 93 LEU A 97 PHE A 101 GLY A 142 GLY A 143 VAL A 146 SER A 221 VAL A 254 LEU A 255 PHE A 303 LEU A 304 SER A 305 PRO A 317 LEU A 318 LEU A 358 ILE A 359 LEU A 363 MET A 364 LEU A 388 HIS A 468	CTX A 1
6OHU_A_CTXA301	6ohu	CTX	Tamoxifen (DB00675)	Homo sapiens	3-BETA-HYDROXYSTEROID-DELTA(8),DELTA(7)-ISOMERASE	EBP	21	LEU A 32 LEU A 35 PHE A 36 THR A 39 VAL A 71 PHE A 74 ILE A 75 ILE A 79 GLU A 80 LEU A 100 TRP A 101 TYR A 104 TYR A 111 MET A 121 GLU A 122 ASP A 162 TYR A 165 TYR A 188 MET A 192 ASN A 193 TRP A 196	CTX A 301
6SXF_A_CTXA307	6sxf	CTX	Tamoxifen (DB00675)	Magnetococcus marinus mc-1	ION TRANSPORT PROTEIN	Ion_trans	4	MET A 222 THR A 225 LYS A 226 GLU A 229	CTX A 307
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1YA4_A_CTXA11","1ya4","CTX","Tamoxifen (DB00675)","Homo sapiens","CES1 PROTEIN","COesterase",11,"GLY A 356;TRP A 357;PRO A 360;MET A 361;TYR A 366;LEU A 368;SER A 369;GLY A 371;LYS A 414;LEU A 418;PRO A 461","CTX A  11\r"],["1YA4_A_CTXA1","1ya4","CTX","Tamoxifen (DB00675)","Homo sapiens","CES1 PROTEIN","COesterase",20,"ALA A  93;LEU A  97;PHE A 101;GLY A 142;GLY A 143;VAL A 146;SER A 221;VAL A 254;LEU A 255;PHE A 303;LEU A 304;SER A 305;PRO A 317;LEU A 318;LEU A 358;ILE A 359;LEU A 363;MET A 364;LEU A 388;HIS A 468","CTX A   1\r"],["6OHU_A_CTXA301","6ohu","CTX","Tamoxifen (DB00675)","Homo sapiens","3-BETA-HYDROXYSTEROID-DELTA(8),DELTA(7)-ISOMERASE","EBP",21,"LEU A  32;LEU A  35;PHE A  36;THR A  39;VAL A  71;PHE A  74;ILE A  75;ILE A  79;GLU A  80;LEU A 100;TRP A 101;TYR A 104;TYR A 111;MET A 121;GLU A 122;ASP A 162;TYR A 165;TYR A 188;MET A 192;ASN A 193;TRP A 196","CTX A 301\r"],["6SXF_A_CTXA307","6sxf","CTX","Tamoxifen (DB00675)","Magnetococcus marinus mc-1","ION TRANSPORT PROTEIN","Ion_trans",4,"MET A 222;THR A 225;LYS A 226;GLU A 229","CTX A 307\r"]]