Ligand ID: R1Q

Drugbank ID:
Vincristine
(DB00541)


Indication:
Vincristine is a vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.


LIST OF BINDING INTERFACES for query 'DB00541'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details
7A69_A_R1QA14007a69 R1QVincristine
(DB00541)
Homo sapiens;
mus musculus
MULTIDRUG RESISTANCE PROTEIN 1 ABC_membrane
ABC_tran
21LEU A  65
MET A  68
MET A  69
PHE A 303
ILE A 306
TYR A 310
LEU A 339
ILE A 340
PHE A 343
SER A 344
GLN A 347
GLN A 725
PHE A 728
GLU A 875
GLN A 946
MET A 949
TYR A 953
PHE A 983
MET A 986
ALA A 987
GLN A 990
R1Q A1400
DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details