Ligand ID: AQ4

Drugbank ID:
Erlotinib
(DB00530)

Indication:
Erlotinib is an EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers.

LIST OF BINDING INTERFACES for query 'DB00530'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1M17_A_AQ4A999	1m17	AQ4	Erlotinib (DB00530)	Homo sapiens	EPIDERMAL GROWTH FACTOR RECEPTOR	PK_Tyr_Ser-Thr	17	LEU A 694 VAL A 702 ALA A 719 LYS A 721 GLU A 738 LEU A 764 ILE A 765 THR A 766 GLN A 767 LEU A 768 MET A 769 PRO A 770 PHE A 771 GLY A 772 LEU A 820 THR A 830 ASP A 831	AQ4 A 999		Details
6DWN_A_AQ4A602	6dwn	AQ4	Erlotinib (DB00530)	Homo sapiens	CYTOCHROME P450 1A1	p450	28	ILE A 115 SER A 116 SER A 120 SER A 122 PHE A 123 TYR A 187 VAL A 218 ASN A 222 ASN A 223 PHE A 224 GLY A 225 ALA A 250 PHE A 251 LEU A 254 ASN A 255 PHE A 258 LEU A 312 ASP A 313 GLY A 316 ALA A 317 PHE A 319 ASP A 320 THR A 321 VAL A 382 ILE A 386 LEU A 496 THR A 497 LYS A 499	AQ4 A 602		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1M17_A_AQ4A999","1m17","AQ4","Erlotinib (DB00530)","Homo sapiens","EPIDERMAL GROWTH FACTOR RECEPTOR","PK_Tyr_Ser-Thr",17,"LEU A 694;VAL A 702;ALA A 719;LYS A 721;GLU A 738;LEU A 764;ILE A 765;THR A 766;GLN A 767;LEU A 768;MET A 769;PRO A 770;PHE A 771;GLY A 772;LEU A 820;THR A 830;ASP A 831","AQ4 A 999\r"],["6DWN_A_AQ4A602","6dwn","AQ4","Erlotinib (DB00530)","Homo sapiens","CYTOCHROME P450 1A1","p450",28,"ILE A 115;SER A 116;SER A 120;SER A 122;PHE A 123;TYR A 187;VAL A 218;ASN A 222;ASN A 223;PHE A 224;GLY A 225;ALA A 250;PHE A 251;LEU A 254;ASN A 255;PHE A 258;LEU A 312;ASP A 313;GLY A 316;ALA A 317;PHE A 319;ASP A 320;THR A 321;VAL A 382;ILE A 386;LEU A 496;THR A 497;LYS A 499","AQ4 A 602\r"]]