Results: Ligand

Ligand ID: SNL

Drugbank ID:
Spironolactone
(DB00421)

Indication:
Spironolactone is an aldosterone receptor antagonist used for the treatment of hypertension, hyperaldosteronism, edema due to various conditions, hirsutism (off-label) and hypokalemia.

LIST OF BINDING INTERFACES for query 'DB00421'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2AB2_A_SNLA502	2ab2	SNL	Spironolactone (DB00421)	Homo sapiens	MINERALOCORTICOID RECEPTOR	Hormone_recep	22	LEU A 766 LEU A 769 ASN A 770 LEU A 772 ALA A 773 GLN A 776 TRP A 806 MET A 807 LEU A 810 SER A 811 LEU A 814 ARG A 817 PHE A 829 MET A 845 CYS A 849 MET A 852 LEU A 938 PHE A 941 CYS A 942 THR A 945 VAL A 954 PHE A 956	SNL A 502
3VHU_A_SNLA1001	3vhu	SNL	Spironolactone (DB00421)	Homo sapiens	MINERALOCORTICOID RECEPTOR	Hormone_recep	22	LEU A 766 LEU A 769 ASN A 770 LEU A 772 ALA A 773 GLN A 776 TRP A 806 MET A 807 LEU A 810 SER A 811 LEU A 814 ARG A 817 PHE A 829 MET A 845 LEU A 848 CYS A 849 MET A 852 LEU A 938 PHE A 941 CYS A 942 THR A 945 PHE A 956	SNL A1001
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details