Results: Ligand

Ligand ID: 95E

Drugbank ID:
Ethambutol
(DB00330)

Indication:
Ethambutol is an antituberculosis agent used in the prophylaxis and treatment of tuberculosis (TB).

LIST OF BINDING INTERFACES for query 'DB00330'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
5NR3_A_95EA401	5nr3	95E	Ethambutol (DB00330)	Homo sapiens	DNA (CYTOSINE-5)-METHYLTRANSFERASE 3B	PWWP	7	ILE A 233 PHE A 236 TRP A 239 TRP A 263 ASP A 266 LYS A 268 SER A 297	95E A 401
7BVC_B_95EB1203	7bvc	95E	Ethambutol (DB00330)	Mycolicibacterium smegmatis mc2 155	INTEGRAL MEMBRANE INDOLYLACETYLINOSITOL ARABINOSYLTRANSFERASE EMBB	Arabino_trans_C Arabino_trans_N Arabinose_trans	12	ASP B 285 TYR B 288 ILE B 289 ASN B 304 GLU B 313 TYR B 320 ARG B 389 GLN B 431 TRP B 578 HIS B 580 TRP B 972 TRP B1012	95E B1203
7BVE_A_95EA1103	7bve	95E	Ethambutol (DB00330)	Mycolicibacterium smegmatis (strain atcc 700084 / mc(2)155); mycolicibacterium smegmatis mc2 155	INTEGRAL MEMBRANE INDOLYLACETYLINOSITOL ARABINOSYLTRANSFERASE EMBC	Arabino_trans_C Arabino_trans_N Arabinose_trans	12	ASP A 279 TYR A 282 ILE A 283 ASN A 298 TRP A 302 GLU A 307 TYR A 314 ARG A 383 TRP A 572 HIS A 574 TRP A 965 VAL A1004	95E A1103
7BVF_B_95EB1402	7bvf	95E	Ethambutol (DB00330)	Mycobacterium tuberculosis h37rv; mycolicibacterium smegmatis mc2 155	PROBABLE ARABINOSYLTRANSFERASE B	Arabino_trans_C Arabino_trans_N Arabinose_trans	12	SER B 298 ASP B 299 TYR B 302 ILE B 303 MET B 306 GLU B 327 TYR B 334 ARG B 403 GLN B 445 HIS B 594 TRP B 988 TRP B1028	95E B1402
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["5NR3_A_95EA401","5nr3","95E","Ethambutol (DB00330)","Homo sapiens","DNA (CYTOSINE-5)-METHYLTRANSFERASE 3B","PWWP",7,"ILE A 233;PHE A 236;TRP A 239;TRP A 263;ASP A 266;LYS A 268;SER A 297","95E A 401\r"],["7BVC_B_95EB1203","7bvc","95E","Ethambutol (DB00330)","Mycolicibacterium smegmatis mc2 155","INTEGRAL MEMBRANE INDOLYLACETYLINOSITOL ARABINOSYLTRANSFERASE EMBB","Arabino_trans_C;Arabino_trans_N;Arabinose_trans",12,"ASP B 285;TYR B 288;ILE B 289;ASN B 304;GLU B 313;TYR B 320;ARG B 389;GLN B 431;TRP B 578;HIS B 580;TRP B 972;TRP B1012","95E B1203\r"],["7BVE_A_95EA1103","7bve","95E","Ethambutol (DB00330)","Mycolicibacterium smegmatis (strain atcc 700084 \/ mc(2)155);mycolicibacterium smegmatis mc2 155","INTEGRAL MEMBRANE INDOLYLACETYLINOSITOL ARABINOSYLTRANSFERASE EMBC","Arabino_trans_C;Arabino_trans_N;Arabinose_trans",12,"ASP A 279;TYR A 282;ILE A 283;ASN A 298;TRP A 302;GLU A 307;TYR A 314;ARG A 383;TRP A 572;HIS A 574;TRP A 965;VAL A1004","95E A1103\r"],["7BVF_B_95EB1402","7bvf","95E","Ethambutol (DB00330)","Mycobacterium tuberculosis h37rv;mycolicibacterium smegmatis mc2 155","PROBABLE ARABINOSYLTRANSFERASE B","Arabino_trans_C;Arabino_trans_N;Arabinose_trans",12,"SER B 298;ASP B 299;TYR B 302;ILE B 303;MET B 306;GLU B 327;TYR B 334;ARG B 403;GLN B 445;HIS B 594;TRP B 988;TRP B1028","95E B1402\r"]]