Ligand ID: 210

Drugbank ID:
Pamidronic acid
(DB00282)

Indication:
Pamidronic acid is a bisphosphonate used to treat Paget's disease, to treat hypercalcemia of malignancy, and to treat osteolytic bone lesions.

LIST OF BINDING INTERFACES for query 'DB00282'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
3SDR_A_210A822	3sdr	210	Pamidronic acid (DB00282)	Abies grandis	ALPHA-BISABOLENE SYNTHASE	Terpene_synth Terpene_synth_C	6	ASP A 566 ASP A 567 ASP A 570 ILE A 667 ARG A 710 ASP A 713	210 A 822		Details
4KPJ_A_210A901	4kpj	210	Pamidronic acid (DB00282)	Homo sapiens	FARNESYL PYROPHOSPHATE SYNTHASE	polyprenyl_synt	12	LEU A 100 ASP A 103 ASP A 104 ASP A 107 ARG A 112 LYS A 200 THR A 201 GLN A 240 ASP A 243 ASP A 244 LYS A 257 ASP A 261	210 A 901		Details
5ERM_A_210A401	5erm	210	Pamidronic acid (DB00282)	Phomopsis amygdali	FUSICOCCADIENE SYNTHASE	Terpene_syn_C_2	12	PHE A  89 ASP A  92 ASP A  96 ARG A 188 ASP A 191 VAL A 192 ASN A 232 SER A 236 LYS A 239 GLU A 240 ARG A 325 TYR A 326	210 A 401		Details
5ERO_A_210A804	5ero	210	Pamidronic acid (DB00282)	Phomopsis amygdali	FUSICOCCADIENE SYNTHASE	polyprenyl_synt	14	LEU A 471 ASP A 474 ASP A 475 ASP A 478 ARG A 483 LYS A 561 THR A 562 PHE A 601 GLN A 602 ASP A 605 ASP A 606 LYS A 619 ASP A 624 LYS A 629	210 A 804		Details
7KJ8_A_210A405	7kj8	210	Pamidronic acid (DB00282)	Streptomyces coelicolor	EPI-ISOZIZAENE SYNTHASE	Terpene_syn_C_2	11	PHE A  96 ASP A  99 TYR A 172 ARG A 194 PHE A 198 ASN A 240 SER A 244 LYS A 247 GLU A 248 ARG A 338 TYR A 339	210 A 405		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["3SDR_A_210A822","3sdr","210","Pamidronic acid (DB00282)","Abies grandis","ALPHA-BISABOLENE SYNTHASE","Terpene_synth;Terpene_synth_C",6,"ASP A 566;ASP A 567;ASP A 570;ILE A 667;ARG A 710;ASP A 713","210 A 822\r"],["4KPJ_A_210A901","4kpj","210","Pamidronic acid (DB00282)","Homo sapiens","FARNESYL PYROPHOSPHATE SYNTHASE","polyprenyl_synt",12,"LEU A 100;ASP A 103;ASP A 104;ASP A 107;ARG A 112;LYS A 200;THR A 201;GLN A 240;ASP A 243;ASP A 244;LYS A 257;ASP A 261","210 A 901\r"],["5ERM_A_210A401","5erm","210","Pamidronic acid (DB00282)","Phomopsis amygdali","FUSICOCCADIENE SYNTHASE","Terpene_syn_C_2",12,"PHE A 89;ASP A 92;ASP A 96;ARG A 188;ASP A 191;VAL A 192;ASN A 232;SER A 236;LYS A 239;GLU A 240;ARG A 325;TYR A 326","210 A 401\r"],["5ERO_A_210A804","5ero","210","Pamidronic acid (DB00282)","Phomopsis amygdali","FUSICOCCADIENE SYNTHASE","polyprenyl_synt",14,"LEU A 471;ASP A 474;ASP A 475;ASP A 478;ARG A 483;LYS A 561;THR A 562;PHE A 601;GLN A 602;ASP A 605;ASP A 606;LYS A 619;ASP A 624;LYS A 629","210 A 804\r"],["7KJ8_A_210A405","7kj8","210","Pamidronic acid (DB00282)","Streptomyces coelicolor","EPI-ISOZIZAENE SYNTHASE","Terpene_syn_C_2",11,"PHE A 96;ASP A 99;TYR A 172;ARG A 194;PHE A 198;ASN A 240;SER A 244;LYS A 247;GLU A 248;ARG A 338;TYR A 339","210 A 405\r"]]