Ligand ID: PZA


Drugbank ID:
DB00339
(Pyrazinamide)


Indication:
For the initial treatment of active tuberculosis in adults and children when combined with other antituberculous agents.

Get human targets for PZA in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'PZA' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
VAL A 157
SER A 158
GLY A 149
VAL A  13
1.60A16.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
VAL A 212
ALA A 210
GLY A   2
ARG A 217
1.53A16.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
ASN A  65
SER A  62
GLY A  79
VAL A  77
1.60A16.01
None
None
K1Y  A 404 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
VAL A 125
ALA A 116
GLY A 138
VAL A 114
1.71A16.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
VAL A 212
ALA A 210
GLY A   2
ARG A 217
1.52A16.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
ASN A  65
SER A  62
GLY A  79
VAL A  77
1.59A16.01
None
None
K1Y  A 404 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
VAL A 125
ALA A 116
GLY A 138
VAL A 114
1.72A16.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
VAL A 157
SER A 158
GLY A 149
VAL A  13
1.61A16.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		4 / 7
VAL A 976
SER A 975
ALA A 972
VAL C1164
1.29A17.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6lxt SPIKE PROTEIN S2,
SPIKE PROTEIN S2
(SARS-CoV-2)		4 / 7
VAL B 976
SER B 975
ALA B 972
VAL A1164
1.49A17.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
GLU C 290
PHE C 291
GLN C 127
1.72A19.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6m71 NSP12
(SARS-CoV-2)		4 / 7
ASN A 703
ALA A 762
GLY A 616
VAL A 764
1.36A17.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6m71 NSP12
(SARS-CoV-2)		4 / 7
ASN A 356
VAL A 535
ALA A 660
GLY A 327
1.14A17.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6m71 NSP12
(SARS-CoV-2)		4 / 7
ASN A 356
VAL A 535
ALA A 660
GLY A 327
1.16A17.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6m71 NSP12
(SARS-CoV-2)		4 / 7
ASN A 703
ALA A 762
GLY A 616
VAL A 764
1.38A17.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
ASN A 764
VAL A 736
SER A 735
GLY C 593
1.15A14.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6vxs NSP3
(SARS-CoV-2)		4 / 7
VAL B  36
ALA B  38
GLY B  97
VAL B  95
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6vxs NSP3
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  38
GLY A  97
VAL A  95
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6vxs NSP3
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  38
GLY A  97
VAL A  95
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6vxs NSP3
(SARS-CoV-2)		4 / 7
VAL B  36
ALA B  38
GLY B  97
VAL B  95
1.09A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 7
ASN A   5
VAL A   6
ALA A  60
GLY A  14
VAL A  10
1.69A24.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 7
SER C 375
ALA C 435
GLY C 404
VAL C 407
1.72A17.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 7
ASN C 334
ALA C 363
GLY C 526
VAL C 524
1.78A17.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 7
ASN C 334
ALA C 363
GLY C 526
VAL C 524
1.77A17.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 7
SER C 375
ALA C 435
GLY C 404
VAL C 407
1.74A17.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w4h NSP10
NSP16
(SARS-CoV-2)		4 / 7
SER A6903
ALA B4324
GLY B4322
VAL B4295
1.18A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w4h NSP10
NSP16
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
SER A6872
ALA A6877
GLY A6879
1.69A17.80
BDF  B4403 (-3.8A)
None
SAM  A7102 ( 4.5A)
None
SAM  A7102 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
VAL A6876
SER A6872
ALA A6877
GLY A6879
VAL B4295
1.71A
None
SAM  A7104 (-4.4A)
None
SAM  A7104 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ASN A7033
ALA A6808
GLY A6806
VAL A6992
1.50A19.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6842
ALA A6881
GLY B4322
VAL B4295
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
SER A6872
ALA A6877
GLY A6879
1.68A
None
None
SAM  A7104 (-4.4A)
None
SAM  A7104 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
VAL A6995
SER A7038
ALA A6997
GLY A6806
1.67A19.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ASN A7033
ALA A6808
GLY A6806
VAL A6992
1.49A19.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
VAL A6902
SER A6903
ALA A6877
GLY A6871
1.36A
None
None
None
SAM  A7104 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ASN A6994
VAL A6995
SER A7038
ALA A6832
1.76A19.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6902
SER A6903
ALA B4324
GLY B4322
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
VAL A6995
SER A7038
ALA A6997
GLY A6806
1.67A19.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6882
ALA A6881
GLY B4322
VAL B4295
1.79A19.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL B4295
ALA A6881
GLY A6879
VAL A6842
1.71A17.90
None
None
SAM  A7104 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ASN A6994
VAL A6995
SER A7038
ALA A6832
1.75A19.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
VAL A6902
SER A6903
ALA A6877
GLY A6871
1.36A
None
None
None
SAM  A7104 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6882
ALA A6881
GLY B4322
VAL B4295
1.79A19.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6902
SER A6903
ALA B4324
GLY B4322
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
ASN B4293
VAL A6876
GLY B4322
ARG B4331
1.53A17.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6876
ALA B4324
GLY B4322
VAL B4295
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
SER A6872
ALA A6877
GLY A6879
1.69A
None
None
SAM  A7104 (-4.4A)
None
SAM  A7104 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
VAL A6876
SER A6872
ALA A6877
GLY A6879
VAL B4295
1.72A
None
SAM  A7104 (-4.4A)
None
SAM  A7104 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6876
ALA B4324
GLY B4322
VAL B4295
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6842
ALA A6881
GLY B4322
VAL B4295
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
SER A6903
ALA B4324
GLY B4322
VAL B4295
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
ASN B4293
VAL A6876
GLY B4322
ARG B4331
1.52A17.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
SER A6903
ALA B4324
GLY B4322
VAL B4295
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
ASN A  37
ALA A 112
GLY A  79
VAL A  96
1.75A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  38
GLY A  97
VAL A  95
1.05A
None
AMP  A 201 ( 3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
SER B 111
ALA B 112
GLY B  97
VAL B  96
1.54A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
VAL B  36
ALA B  39
GLY B  97
VAL B  95
1.71A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
VAL B  36
ALA B  39
GLY B  97
VAL B  95
1.72A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
VAL B  36
ALA B  38
GLY B  97
VAL B  95
1.05A
None
MES  B 201 ( 3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
ASN B  37
ALA B 112
GLY B  79
VAL B  96
1.73A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
SER A 111
ALA A 112
GLY A  97
VAL A  96
1.55A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
ASN B 115
VAL B  95
ALA B  39
VAL B  36
1.64A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
ASN B  37
ALA B 112
GLY B  79
VAL B  96
1.75A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
VAL B  36
ALA B  38
GLY B  97
VAL B  95
1.06A
None
MES  B 201 ( 3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
ASN A 115
VAL A  95
ALA A  39
VAL A  36
1.62A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
ASN B  37
VAL B  49
ALA B  52
VAL B  24
1.72A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
SER B 111
ALA B 112
GLY B  97
VAL B  77
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
ASN A 115
VAL A  95
ALA A  39
VAL A  36
1.61A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
ASN B  37
VAL B  49
ALA B  52
VAL B  24
1.74A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
ASN B 115
VAL B  95
ALA B  39
VAL B  36
1.63A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
ASN B 115
VAL B  95
SER B  80
VAL B  36
1.48A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
SER B 111
ALA B 112
GLY B  97
VAL B  96
1.53A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
ASN A  37
ALA A 112
GLY A  79
VAL A  96
1.73A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  39
GLY A  97
VAL A  95
1.71A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
SER A 111
ALA A 112
GLY A  97
VAL A  95
1.75A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
SER A 111
ALA A 112
GLY A  97
VAL A  95
1.75A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
SER A 111
ALA A 112
GLY A  97
VAL A  96
1.55A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  38
GLY A  97
VAL A  95
1.06A
None
AMP  A 201 ( 3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
ASN A  37
VAL A  49
ALA A  52
VAL A  24
1.74A19.29
None
AMP  A 201 ( 3.7A)
AMP  A 201 ( 4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  39
GLY A  97
VAL A  95
1.71A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
ASN A 115
VAL A  95
SER A  80
VAL A  36
1.49A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
ASN A 115
VAL A  95
SER A  80
VAL A  36
1.49A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
ASN A  37
VAL A  49
ALA A  52
VAL A  24
1.72A19.29
None
AMP  A 201 ( 3.7A)
AMP  A 201 ( 4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
ASN B 115
VAL B  95
SER B  80
VAL B  36
1.48A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w6y NSP3
(SARS-CoV-2)		4 / 7
SER B 111
ALA B 112
GLY B  97
VAL B  77
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 7
ASN D4293
VAL C6876
ALA C6877
GLY D4322
ARG D4331
1.77A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 7
ASN D4293
VAL C6876
SER C6872
ALA C6877
GLY C6879
1.73A17.80
None
None
SAM  C7105 ( 4.4A)
None
SAM  C7105 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 7
VAL C6876
SER C6872
ALA C6877
GLY C6879
VAL D4295
1.71A18.91
None
SAM  C7105 ( 4.4A)
None
SAM  C7105 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 7
VAL A6876
SER A6872
ALA A6877
GLY A6879
VAL B4295
1.72A18.91
None
SAM  A7102 ( 4.6A)
None
SAM  A7102 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
ASN A7095
SER C6907
ALA C6905
GLY D4347
1.48A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
SER A6872
ALA A6877
GLY A6879
1.73A17.80
None
None
SAM  A7102 ( 4.6A)
None
SAM  A7102 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ALA C7024
GLY C7019
VAL C7021
ARG C6817
1.67A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ASN C7033
ALA C6808
GLY C6806
VAL C6992
1.47A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 7
VAL A6995
SER A7038
ALA A6997
GLY A6806
1.62A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL A6842
ALA A6881
GLY B4322
VAL B4295
1.41A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
SER A6872
ALA A6877
GLY A6879
1.72A17.80
None
None
SAM  A7102 ( 4.6A)
None
SAM  A7102 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
SER A6903
ALA B4324
GLY B4322
VAL B4295
1.15A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL D4295
SER D4325
ALA C6877
GLY C6875
1.80A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL A6876
ALA B4324
GLY B4322
VAL B4295
1.41A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL C6876
ALA D4324
GLY D4322
VAL D4295
1.38A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL B4295
SER B4325
ALA A6877
GLY A6875
1.80A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 7
VAL A6876
SER A6872
ALA A6877
GLY A6879
VAL B4295
1.71A18.91
None
SAM  A7102 ( 4.6A)
None
SAM  A7102 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ALA C7024
GLY C7019
VAL C7021
ARG C6817
1.68A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL C6876
ALA D4324
GLY D4322
VAL D4295
1.38A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
SER C6903
ALA D4324
GLY D4322
VAL D4295
1.16A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 7
VAL A6995
SER A7038
ALA A6997
GLY A6806
1.62A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 7
VAL A6902
SER A6903
ALA A6877
GLY A6871
1.48A18.91
None
None
None
SAM  A7102 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
SER C6903
ALA D4324
GLY D4322
VAL D4295
1.15A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 7
ASN D4293
VAL C6876
SER C6872
ALA C6877
GLY C6879
1.73A17.80
None
None
SAM  C7105 ( 4.4A)
None
SAM  C7105 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 7
VAL C6902
SER C6903
ALA C6877
GLY C6871
1.49A18.91
None
None
None
SAM  C7105 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL A6876
ALA B4324
GLY B4322
VAL B4295
1.41A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL C6902
SER C6903
ALA D4324
GLY D4322
1.25A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 7
VAL A6902
SER A6903
ALA A6877
GLY A6871
1.49A18.91
None
None
None
SAM  A7102 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
ASN A7095
SER C6907
ALA C6905
GLY D4347
1.48A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL A6842
ALA A6881
GLY B4322
VAL B4295
1.42A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
ALA A6877
GLY B4322
ARG B4331
1.79A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
ALA A6877
GLY B4322
ARG B4331
1.79A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL A6902
SER A6903
ALA B4324
GLY B4322
1.27A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 7
VAL C6995
SER C7038
ALA C6997
GLY C6806
1.65A18.91
None
FMT  C7111 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
SER A6903
ALA B4324
GLY B4322
VAL B4295
1.16A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL C6842
ALA C6881
GLY D4322
VAL D4295
1.42A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL A6902
SER A6903
ALA B4324
GLY B4322
1.26A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 7
ASN C7033
ALA C6808
GLY C6806
VAL C6992
1.48A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 7
VAL C6995
SER C7038
ALA C6997
GLY C6806
1.66A18.91
None
FMT  C7111 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 7
ASN D4293
VAL C6876
ALA C6877
GLY D4322
ARG D4331
1.77A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL C6842
ALA C6881
GLY D4322
VAL D4295
1.42A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 7
VAL C6902
SER C6903
ALA C6877
GLY C6871
1.48A18.91
None
None
None
SAM  C7105 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL C6902
SER C6903
ALA D4324
GLY D4322
1.24A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 7
VAL C6876
SER C6872
ALA C6877
GLY C6879
VAL D4295
1.72A18.91
None
SAM  C7105 ( 4.4A)
None
SAM  C7105 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		4 / 7
ASN A  33
VAL A  -6
GLY A 100
VAL A 102
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		4 / 7
ASN A  33
VAL A  -6
GLY A 100
VAL A 102
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wcf NSP3
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  38
GLY A  97
VAL A  95
1.07A
None
MES  A 201 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wcf NSP3
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  38
GLY A  97
VAL A  95
1.08A
None
MES  A 201 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wen NSP3
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  38
GLY A  97
VAL A  95
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wen NSP3
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  38
GLY A  97
VAL A  95
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wey NSP3
(SARS-CoV-2)		4 / 7
VAL A 240
ALA A 242
GLY A 301
VAL A 299
1.04A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wey NSP3
(SARS-CoV-2)		4 / 7
VAL A 240
ALA A 242
GLY A 301
VAL A 299
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
ASN D4293
VAL C6876
ALA C6877
GLY D4322
ARG D4331
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL C6876
ALA D4324
GLY D4322
VAL D4295
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
SER A6872
ALA A6877
GLY A6879
1.68A
None
None
SAH  A7102 ( 4.6A)
None
SAH  A7102 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6902
SER A6903
ALA B4324
GLY B4322
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
SER C6903
ALA D4324
GLY D4322
VAL D4295
1.14A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
SER A6903
ALA B4324
GLY B4322
VAL B4295
1.15A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
ALA A6877
GLY B4322
ARG B4331
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
ASN D4293
VAL C6876
SER C6872
ALA C6877
GLY C6879
1.66A
None
None
SAH  C7102 (-4.7A)
None
SAH  C7102 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
ASN D4293
VAL C6876
ALA C6877
GLY D4322
ARG D4331
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL C6902
SER C6903
ALA D4324
GLY D4322
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
VAL C6876
SER C6872
ALA C6877
GLY C6879
VAL D4295
1.70A
None
SAH  C7102 (-4.7A)
None
SAH  C7102 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
VAL A6876
SER A6872
ALA A6877
GLY A6879
VAL B4295
1.70A
None
SAH  A7102 ( 4.6A)
None
SAH  A7102 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL C6842
ALA C6881
GLY D4322
VAL D4295
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6876
ALA B4324
GLY B4322
VAL B4295
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
SER C6903
ALA D4324
GLY D4322
VAL D4295
1.13A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6842
ALA A6881
GLY B4322
VAL B4295
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6842
ALA A6881
GLY B4322
VAL B4295
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
VAL C6876
SER C6872
ALA C6877
GLY C6879
VAL D4295
1.71A
None
SAH  C7102 (-4.7A)
None
SAH  C7102 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6876
ALA B4324
GLY B4322
VAL B4295
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6902
SER A6903
ALA B4324
GLY B4322
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL C6876
ALA D4324
GLY D4322
VAL D4295
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
ALA A6877
GLY B4322
ARG B4331
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL C6842
ALA C6881
GLY D4322
VAL D4295
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
VAL A6876
SER A6872
ALA A6877
GLY A6879
VAL B4295
1.69A
None
SAH  A7102 ( 4.6A)
None
SAH  A7102 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
SER A6903
ALA B4324
GLY B4322
VAL B4295
1.15A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
ASN D4293
VAL C6876
SER C6872
ALA C6877
GLY C6879
1.66A
None
None
SAH  C7102 (-4.7A)
None
SAH  C7102 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL C6902
SER C6903
ALA D4324
GLY D4322
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
SER A6872
ALA A6877
GLY A6879
1.68A
None
None
SAH  A7102 ( 4.6A)
None
SAH  A7102 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 7
VAL A6876
SER A6872
ALA A6877
GLY A6879
VAL B4295
1.70A
None
SFG  A7103 ( 4.5A)
None
SFG  A7103 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 7
VAL C6876
SER C6872
ALA C6877
GLY C6879
VAL D4295
1.69A
None
SFG  C7103 ( 4.5A)
None
SFG  C7103 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 7
ASN D4293
VAL C6876
SER C6872
ALA C6877
GLY C6879
1.71A
None
None
SFG  C7103 ( 4.5A)
None
SFG  C7103 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
ALA A6877
GLY B4322
ARG B4331
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 7
VAL A6876
SER A6872
ALA A6877
GLY A6879
VAL B4295
1.69A
None
SFG  A7103 ( 4.5A)
None
SFG  A7103 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL C6902
SER C6903
ALA D4324
GLY D4322
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 7
ASN D4293
VAL C6876
ALA C6877
GLY D4322
ARG D4331
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL A6902
SER A6903
ALA B4324
GLY B4322
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 7
VAL C6876
SER C6872
ALA C6877
GLY C6879
VAL D4295
1.70A
None
SFG  C7103 ( 4.5A)
None
SFG  C7103 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL C6876
ALA D4324
GLY D4322
VAL D4295
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
SER C6903
ALA D4324
GLY D4322
VAL D4295
1.14A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
SER A6903
ALA B4324
GLY B4322
VAL B4295
1.15A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
ALA A6877
GLY B4322
ARG B4331
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL A6876
ALA B4324
GLY B4322
VAL B4295
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL C6902
SER C6903
ALA D4324
GLY D4322
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL A6842
ALA A6881
GLY B4322
VAL B4295
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
SER A6903
ALA B4324
GLY B4322
VAL B4295
1.14A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
SER A6872
ALA A6877
GLY A6879
1.71A
None
None
SFG  A7103 ( 4.5A)
None
SFG  A7103 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL A6842
ALA A6881
GLY B4322
VAL B4295
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL C6842
ALA C6881
GLY D4322
VAL D4295
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL C6876
ALA D4324
GLY D4322
VAL D4295
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
SER C6903
ALA D4324
GLY D4322
VAL D4295
1.15A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 7
ASN D4293
VAL C6876
ALA C6877
GLY D4322
ARG D4331
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL C6842
ALA C6881
GLY D4322
VAL D4295
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 7
ASN D4293
VAL C6876
SER C6872
ALA C6877
GLY C6879
1.70A
None
None
SFG  C7103 ( 4.5A)
None
SFG  C7103 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
ASN A7095
SER C6907
ALA C6905
GLY D4347
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL A6876
ALA B4324
GLY B4322
VAL B4295
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
VAL A6902
SER A6903
ALA B4324
GLY B4322
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
SER A6872
ALA A6877
GLY A6879
1.70A
None
None
SFG  A7103 ( 4.5A)
None
SFG  A7103 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 7
ASN A7095
SER C6907
ALA C6905
GLY D4347
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 7
ASN B   5
VAL B   6
ALA B  60
GLY B  14
VAL B  10
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 7
ASN A   5
VAL A   6
ALA A  60
GLY A  14
VAL A  10
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
VAL B 149
SER B 148
GLY B 126
VAL B 132
1.38A
ACT  B 408 ( 4.0A)
EDO  B 403 (-4.6A)
ACT  B 408 (-4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 7
ASN A   5
VAL A   6
ALA A  60
GLY A  14
VAL A  10
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 7
ASN B   5
VAL B   6
ALA B  60
GLY B  14
VAL B  10
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
VAL B 149
SER B 148
GLY B 126
VAL B 132
1.38A
ACT  B 408 ( 4.0A)
EDO  B 403 (-4.6A)
ACT  B 408 (-4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  38
GLY A  97
VAL A  95
1.05A
None
APR  A 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
SER C 111
ALA C 112
GLY C  97
VAL C  77
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
SER B 111
ALA B 112
GLY B  97
VAL B  77
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
ASN B 115
VAL B  95
SER B  80
VAL B  36
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
ASN B 115
VAL B  95
SER B  80
VAL B  36
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
ASN D 115
VAL D  95
SER D  80
VAL D  36
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
VAL C  36
ALA C  38
GLY C  97
VAL C  95
1.06A
None
APR  C 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
VAL D  36
ALA D  38
GLY D  97
VAL D  95
1.07A
None
APR  D 201 (-3.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
VAL B  36
ALA B  38
GLY B  97
VAL B  95
1.05A
None
APR  B 201 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  38
GLY A  97
VAL A  95
1.06A
None
APR  A 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
ASN D 115
VAL D  95
SER D  80
VAL D  36
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
SER B 111
ALA B 112
GLY B  97
VAL B  77
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
SER D 111
ALA D 112
GLY D  97
VAL D  77
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
VAL C  36
ALA C  38
GLY C  97
VAL C  95
1.07A
None
APR  C 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
SER D 111
ALA D 112
GLY D  97
VAL D  77
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
VAL D  36
ALA D  38
GLY D  97
VAL D  95
1.06A
None
APR  D 201 (-3.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
VAL B  36
ALA B  38
GLY B  97
VAL B  95
1.06A
None
APR  B 201 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
VAL A6876
SER A6872
ALA A6877
GLY A6879
VAL B4295
1.70A
None
SO4  A7109 (-4.5A)
None
SAH  A7101 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6902
SER A6903
ALA B4324
GLY B4322
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6876
ALA B4324
GLY B4322
VAL B4295
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6842
ALA A6881
GLY B4322
VAL B4295
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
ALA A6877
GLY B4322
ARG B4331
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
VAL A6876
SER A6872
ALA A6877
GLY A6879
VAL B4295
1.71A
None
SO4  A7109 (-4.5A)
None
SAH  A7101 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6842
ALA A6881
GLY B4322
VAL B4295
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
SER A6903
ALA B4324
GLY B4322
VAL B4295
1.15A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
SER A6903
ALA B4324
GLY B4322
VAL B4295
1.16A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6876
ALA B4324
GLY B4322
VAL B4295
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
SER A6872
ALA A6877
GLY A6879
1.70A
None
None
SO4  A7109 (-4.5A)
None
SAH  A7101 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
SER A6872
ALA A6877
GLY A6879
1.70A
None
None
SO4  A7109 (-4.5A)
None
SAH  A7101 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 7
VAL A6902
SER A6903
ALA B4324
GLY B4322
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 7
ASN B4293
VAL A6876
ALA A6877
GLY B4322
ARG B4331
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
VAL A 125
ALA A 116
GLY A 138
VAL A 114
1.71A16.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
VAL A 157
SER A 158
GLY A 149
VAL A  13
1.60A16.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
VAL A 125
ALA A 116
GLY A 138
VAL A 114
1.70A16.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
ASN A  65
SER A  62
GLY A  79
VAL A  77
1.60A16.01
DMS  A 402 (-4.0A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
ASN A  65
SER A  62
GLY A  79
VAL A  77
1.61A16.01
DMS  A 402 (-4.0A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
VAL A 157
SER A 158
GLY A 149
VAL A  13
1.60A16.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 7
ASN A  35
VAL A  32
ALA A  94
GLY A  97
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 7
ASN A  35
VAL A  32
ALA A  94
GLY A  97
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
GLU E 484
PHE E 490
GLN E 493
1.77A15.46
None
None
MLI  E 903 ( 4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
GLU E 484
PHE E 490
GLN E 493
1.73A15.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
GLU E 484
PHE E 490
GLN E 493
1.77A15.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
GLU A 484
PHE A 490
GLN A 493
1.77A15.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  38
GLY A  97
VAL A  95
1.08A
None
EDO  A 202 (-3.3A)
EDO  A 202 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL E  36
ALA E  38
GLY E  97
VAL E  95
1.06A
None
EPE  E 202 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER C 111
ALA C 112
GLY C  97
VAL C  77
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
ASN D 115
VAL D  95
SER D  80
VAL D  36
1.46A
EDO  D 201 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
ASN A 115
VAL A  95
SER A  80
VAL A  36
1.46A
EDO  D 201 (-3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL C  36
ALA C  38
GLY C  97
VAL C  95
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL B  36
ALA B  38
GLY B  97
VAL B  95
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER A 111
ALA A 112
GLY A  97
VAL A  77
1.43A
EDO  D 202 (-3.6A)
None
EDO  A 202 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER D 111
ALA D 112
GLY D  97
VAL D  77
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL C  36
ALA C  38
GLY C  97
VAL C  95
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER C 111
ALA C 112
GLY C  97
VAL C  77
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL D  36
ALA D  38
GLY D  97
VAL D  95
1.08A
None
EDO  D 205 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER A 111
ALA A 112
GLY A  97
VAL A  77
1.44A
EDO  D 202 (-3.6A)
None
EDO  A 202 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL D  36
ALA D  38
GLY D  97
VAL D  95
1.07A
None
EDO  D 205 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
ASN D 115
VAL D  95
SER D  80
VAL D  36
1.46A
EDO  D 201 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER E 111
ALA E 112
GLY E  97
VAL E  77
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER D 111
ALA D 112
GLY D  97
VAL D  77
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  38
GLY A  97
VAL A  95
1.07A
None
EDO  A 202 (-3.3A)
EDO  A 202 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL B  36
ALA B  38
GLY B  97
VAL B  95
1.03A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL E  36
ALA E  38
GLY E  97
VAL E  95
1.07A
None
EPE  E 202 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER D 111
ALA D 112
GLY D  97
VAL D  77
1.42A
EDO  A 206 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL D  36
ALA D  38
GLY D  97
VAL D  95
1.06A
None
APR  D 201 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER A 111
ALA A 112
GLY A  97
VAL A  77
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL E  36
ALA E  38
GLY E  97
VAL E  95
1.06A
None
APR  E 201 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
ASN A 115
VAL A  95
SER A  80
VAL A  36
1.46A
EDO  A 207 (-3.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
ASN D 115
VAL D  95
SER D  80
VAL D  36
1.45A
EDO  A 207 ( 3.7A)
None
EDO  D 203 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL C  36
ALA C  38
GLY C  97
VAL C  95
1.06A
None
APR  C 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL D  36
ALA D  38
GLY D  97
VAL D  95
1.08A
None
APR  D 201 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  38
GLY A  97
VAL A  95
1.05A
None
APR  A 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  38
GLY A  97
VAL A  95
1.07A
None
APR  A 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
ASN E 115
VAL E  95
SER E  80
VAL E  36
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL B  36
ALA B  38
GLY B  97
VAL B  95
1.06A
None
APR  B 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL C  36
ALA C  38
GLY C  97
VAL C  95
1.05A
None
APR  C 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
ASN C 115
VAL C  95
SER C  80
VAL C  36
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
ASN D 115
VAL D  95
SER D  80
VAL D  36
1.45A
EDO  A 207 ( 3.7A)
None
EDO  D 203 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER A 111
ALA A 112
GLY A  97
VAL A  77
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER C 111
ALA C 112
GLY C  97
VAL C  77
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER E 111
ALA E 112
GLY E  97
VAL E  77
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER C 111
ALA C 112
GLY C  97
VAL C  77
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL E  36
ALA E  38
GLY E  97
VAL E  95
1.05A
None
APR  E 201 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
ASN A 115
VAL A  95
SER A  80
VAL A  36
1.46A
EDO  A 207 (-3.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER D 111
ALA D 112
GLY D  97
VAL D  77
1.41A
EDO  A 206 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL B  36
ALA B  38
GLY B  97
VAL B  95
1.05A
None
APR  B 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER E 111
ALA E 112
GLY E  97
VAL E  77
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL B  36
ALA B  38
GLY B  97
VAL B  95
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  38
GLY A  97
VAL A  95
1.06A
None
MES  A 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL C  36
ALA C  38
GLY C  97
VAL C  95
1.05A
None
MES  C 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER A 111
ALA A 112
GLY A  97
VAL A  77
1.39A
EDO  C 205 (-3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL B  36
ALA B  38
GLY B  97
VAL B  95
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL C  36
ALA C  38
GLY C  97
VAL C  95
1.06A
None
MES  C 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER C 111
ALA C 112
GLY C  97
VAL C  77
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
ASN A 115
VAL A  95
SER A  80
VAL A  36
1.46A
EDO  A 202 ( 3.5A)
None
EDO  A 204 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER B 111
ALA B 112
GLY B  97
VAL B  77
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER C 111
ALA C 112
GLY C  97
VAL C  77
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL A  36
ALA A  38
GLY A  97
VAL A  95
1.07A
None
MES  A 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER A 111
ALA A 112
GLY A  97
VAL A  77
1.40A
EDO  C 205 (-3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
SER B 111
ALA B 112
GLY B  97
VAL B  77
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		4 / 7
ASN A 703
ALA A 762
GLY A 616
VAL A 764
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		4 / 7
ASN A 356
VAL A 535
ALA A 660
GLY A 327
1.17A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		4 / 7
ASN A 356
VAL A 535
ALA A 660
GLY A 327
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
ASN A 356
VAL A 535
ALA A 660
GLY A 327
1.09A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
ASN A 703
ALA A 762
GLY A 616
VAL A 764
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
ASN A 356
VAL A 535
ALA A 660
GLY A 327
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
ASN A 703
ALA A 762
GLY A 616
VAL A 764
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
ASN A 703
ALA A 762
GLY A 616
VAL A 764
1.46A
None
None
MG  A1005 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
ASN A 356
VAL A 535
ALA A 660
GLY A 327
1.13A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
ASN A 356
VAL A 535
ALA A 660
GLY A 327
1.15A
None