 |
| Ligand ID: K5Y Drugbank ID: DB00938(Salmeterol) Indication:For the treatment of asthma and chronic obstructive pulmonary disease (COPD). |
| DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
View | Interface | RMSD | Seq. Identity (%) |
HETATM | Dock | |
|---|---|---|---|---|---|---|---|---|---|---|
 Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 5r80 | 3C-LIKE PROTEINASE (SARS-CoV-2) | 5 / 12 | VAL A 13ASP A 176PHE A 159ILE A 106ASN A 151 | 1.61A | 20.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 5rfc | 3C-LIKE PROTEINASE (SARS-CoV-2) | 5 / 12 | VAL A 13ASP A 176PHE A 159ILE A 106ASN A 151 | 1.64A | 16.48 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_1 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6lxt | SPIKE PROTEIN S2 (SARS-CoV-2) | 3 / 3 | ASP B1184SER F 939SER F 940 | 1.55A | 16.10 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6lxt | SPIKE PROTEIN S2 (SARS-CoV-2) | 5 / 12 | VAL B 951VAL A1177ASP C 950ASN A 955ILE C1179 | 1.62A | 16.10 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6lze | VIRAL PROTEASE (SARS-CoV-2) | 5 / 12 | VAL A 13ASP A 176PHE A 159ILE A 106ASN A 151 | 1.67A | 20.12 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6m0k | VIRAL PROTEASE (SARS-CoV-2) | 5 / 12 | VAL A 13ASP A 176PHE A 159ILE A 106ASN A 151 | 1.68A | 19.92 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6m2n | 3CL PROTEASE (SARS-CoV-2) | 5 / 12 | VAL C 13ASP C 176PHE C 159ILE C 106ASN C 151 | 1.63A | 20.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6m2n | 3CL PROTEASE (SARS-CoV-2) | 5 / 12 | VAL B 13ASP B 176PHE B 159ILE B 106ASN B 151 | 1.66A | 20.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6m2n | 3CL PROTEASE (SARS-CoV-2) | 5 / 12 | VAL A 13ASP A 176PHE A 159ILE A 106ASN A 151 | 1.67A | 20.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6m2n | 3CL PROTEASE (SARS-CoV-2) | 5 / 12 | VAL D 13ASP D 176PHE D 159ILE D 106ASN D 151 | 1.66A | 20.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6m2q | 3CL PROTEASE (SARS-CoV-2) | 5 / 12 | VAL A 13ASP A 176PHE A 159ILE A 106ASN A 151 | 1.66A | 20.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6m71 | NSP12 (SARS-CoV-2) | 5 / 12 | VAL A 354ASP A 304PHE A 652ASN A 314ILE A 632 | 1.79A | 19.55 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_1 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6m71 | NSP12 (SARS-CoV-2) | 3 / 3 | ASP A 452SER A 682SER A 681 | 1.68A | 19.55 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_1 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6m71 | NSP12 (SARS-CoV-2) | 3 / 3 | ASP A 452SER A 681SER A 682 | 1.45A | 19.55 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6m71 | NSP12 (SARS-CoV-2) | 5 / 12 | VAL A 354VAL A 299PHE A 348ASN A 657ILE A 632 | 1.73A | 19.55 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6m71 | NSP12 (SARS-CoV-2) | 5 / 12 | VAL A 764VAL A 763PHE A 782ASN A 695TYR A 619 | 1.42A | 19.55 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_1 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6vsb | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 3 / 3 | ASP C 663SER C 698SER C 659 | 1.01A | 16.96 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_1 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6w37 | PROTEIN 7A (SARS-CoV-2) | 3 / 3 | ASP A 54SER A 22SER A 21 | 1.60A | 8.55 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6w41 | SPIKE PROTEIN S1 (SARS-CoV-2) | 5 / 12 | VAL C 512VAL C 510ASP C 427PHE C 429TYR C 380 | 1.78A | 17.20 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6w4h | NSP16 (SARS-CoV-2) | 5 / 12 | VAL A6894ASP A6912PHE A6954HIS A6917TYR A6950 | 1.61A | 19.91 | NoneSAM A7102 (-3.6A)NoneNoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6w63 | 3C-LIKE PROTEINASE (SARS-CoV-2) | 5 / 12 | VAL A 13ASP A 176PHE A 159ILE A 106ASN A 151 | 1.68A | 20.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_1 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6w75 | NSP16 (SARS-CoV-2) | 3 / 3 | ASP C6928SER C7000SER C6999 | 1.36A | 16.25 | SAM C7105 ( 3.7A)FMT C7110 ( 2.8A)FMT C7108 ( 2.7A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_1 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6wkq | NSP16 (SARS-CoV-2) | 3 / 3 | ASP C6928SER C7000SER C6999 | 1.37A | 19.91 | SFG C7103 ( 3.7A)FMT C7110 ( 3.0A)FMT C7110 ( 3.1A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6wnp | 3C-LIKE PROTEINASE (SARS-CoV-2) | 5 / 12 | VAL A 13ASP A 176PHE A 159ILE A 106ASN A 151 | 1.68A | 20.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6wqf | 3C-LIKE PROTEINASE (SARS-CoV-2) | 5 / 12 | VAL A 13ASP A 176PHE A 159ILE A 106ASN A 151 | 1.65A | 20.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6yb7 | REPLICASEPOLYPROTEIN 1AB (SARS-CoV-2) | 5 / 12 | VAL A 13ASP A 176PHE A 159ILE A 106ASN A 151 | 1.64A | 16.48 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_1 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6yhu | REPLICASEPOLYPROTEIN 1A (SARS-CoV-2) | 3 / 3 | ASP A 5SER C 4SER C 1 | 1.76A | 9.05 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_1 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6yhu | REPLICASEPOLYPROTEIN 1A (SARS-CoV-2) | 3 / 3 | ASP C 5SER A 4SER A 1 | 1.79A | 9.05 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_1 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6yhu | REPLICASEPOLYPROTEIN 1A (SARS-CoV-2) | 3 / 3 | ASP C 5SER A 1SER A 4 | 1.09A | 9.05 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6yla | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | VAL E 512VAL E 510ASP E 427PHE E 429TYR E 380 | 1.80A | 15.14 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6yla | LIGHT CHAINSPIKE GLYCOPROTEIN (Homosapiens;SARS-CoV-2) | 5 / 12 | VAL A 433ASP A 428PHE A 429PHE A 515ILE C 34 | 1.76A | 15.14 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6ym0 | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | VAL E 512VAL E 510ASP E 427PHE E 429TYR E 380 | 1.80A | 15.14 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6ynq | REPLICASEPOLYPROTEIN 1AB (SARS-CoV-2) | 5 / 12 | VAL A 13ASP A 176PHE A 159ILE A 106ASN A 151 | 1.65A | 20.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6yor | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | VAL A 512VAL A 510ASP A 427PHE A 429TYR A 380 | 1.79A | 15.02 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6yor | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | VAL E 512VAL E 510ASP E 427PHE E 429TYR E 380 | 1.80A | 15.02 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6yt8 | REPLICASEPOLYPROTEIN 1AB (SARS-CoV-2) | 5 / 12 | VAL A 13ASP A 176PHE A 159ILE A 106ASN A 151 | 1.64A | 20.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_1 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6ywk | NSP3 MACRODOMAIN (SARS-CoV-2) | 3 / 3 | ASP B 66SER E 167SER E 166 | 1.75A | 17.36 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_1 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6ywk | NSP3 MACRODOMAIN (SARS-CoV-2) | 3 / 3 | ASP B 66SER E 166SER E 167 | 1.14A | 17.36 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_1 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6ywl | NSP3 MACRODOMAIN (SARS-CoV-2) | 3 / 3 | ASP B 66SER E 166SER E 167 | 1.10A | 17.36 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_1 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 6ywl | NSP3 MACRODOMAIN (SARS-CoV-2) | 3 / 3 | ASP B 66SER E 167SER E 166 | 1.73A | 17.36 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 7bqy | MAIN PROTEASE (SARS-CoV-2) | 5 / 12 | VAL A 13ASP A 176PHE A 159ILE A 106ASN A 151 | 1.67A | 20.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_1 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 7btf | NSP12NSP7 (SARS-CoV-2) | 3 / 3 | ASP A 421SER C 4SER C 1 | 1.75A | 19.55 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 7btf | NSP12 (SARS-CoV-2) | 5 / 12 | VAL A 354VAL A 299PHE A 348ASN A 657ILE A 632 | 1.78A | 19.55 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_1 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 7btf | NSP12 (SARS-CoV-2) | 3 / 3 | ASP A 291SER A 236SER A 239 | 1.16A | 19.55 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_1 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 7btf | NSP12NSP7 (SARS-CoV-2) | 3 / 3 | ASP A 421SER C 1SER C 4 | 0.79A | 19.55 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 7btf | NSP12 (SARS-CoV-2) | 5 / 12 | VAL A 764VAL A 763PHE A 782ASN A 695TYR A 619 | 1.31A | 19.55 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 7buy | VIRUS MAIN PROTEASE (SARS-CoV-2) | 5 / 12 | VAL A 13ASP A 176PHE A 159ILE A 106ASN A 151 | 1.67A | 20.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MXT_A_K5YA1401_0 (ENDOLYSIN, BETA-2ADRENERGIC RECEPTORCHIMERA) | 7bv1 | NSP12 (SARS-CoV-2) | 5 / 12 | VAL A 764VAL A 763PHE A 782ASN A 695TYR A 619 | 1.43A | 19.64 | None |