Ligand ID: BZ1


Drugbank ID:
DB01194
(Brinzolamide)


Indication:
For the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.

Get human targets for BZ1 in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'BZ1' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		5r84 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
HIS A 164
VAL A  13
LEU A  30
1.20A21.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.79A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
HIS A  41
HIS A 164
VAL A  42
PHE A  66
LEU A  87
1.66A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
VAL A  73
GLY A 120
VAL A  18
LEU A  75
THR A  93
1.75A18.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
HIS A 163
VAL A  20
LEU A  27
1.58A18.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.73A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.72A18.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
HIS A 164
VAL A  13
LEU A  30
1.21A18.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		6lu7 MAIN PROTEASE
(SARS-CoV-2)		5 / 10
HIS A  41
HIS A 164
VAL A  42
PHE A  66
LEU A  87
1.56A19.09
PJE  C   5 ( 4.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A  58
HIS A 164
GLY A  79
VAL A  77
VAL A  42
1.62A21.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 10
HIS A  41
HIS A 164
VAL A  42
PHE A  66
LEU A  87
1.68A19.36
ALC  D   2 ( 4.1A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6lze VIRAL PROTEASE
(SARS-CoV-2)		3 / 3
HIS A 164
VAL A  13
LEU A  30
1.25A21.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.64A21.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 10
HIS A  41
HIS A 164
VAL A  42
PHE A  66
LEU A  87
1.67A19.13
N0A  D   2 ( 4.0A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		3 / 3
HIS A 164
VAL A  13
LEU A  30
1.24A21.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A  58
HIS A 164
GLY A  79
VAL A  77
VAL A  42
1.65A21.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
HIS D  41
HIS D 164
VAL D  42
PHE D  66
LEU D  87
1.62A19.09
3WL  D 401 (-3.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
HIS A  41
HIS A 164
VAL A  42
PHE A  66
LEU A  87
1.63A19.09
3WL  A 401 (-3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
VAL A 297
GLY D  71
VAL D  73
THR A 304
THR A 257
1.57A21.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A  58
HIS A 164
GLY A  79
VAL A  77
VAL A  42
1.59A21.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU C  58
HIS C 164
GLY C  79
VAL C  77
VAL C  42
1.56A21.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU D 205
VAL D 247
LEU D 262
THR D 224
THR D 225
1.62A21.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU D  58
HIS D 164
GLY D  79
VAL D  77
VAL D  42
1.64A21.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLN C 244
VAL C 247
LEU C 262
THR C 225
THR C 226
1.68A21.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
HIS B  41
HIS B 164
VAL B  42
PHE B  66
LEU B  87
1.64A19.09
3WL  B 401 (-3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU B  58
HIS B 164
GLY B  79
VAL B  77
VAL B  42
1.59A21.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
HIS A 164
VAL A  13
LEU A  30
1.19A21.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
HIS C  41
HIS C 164
VAL C  42
PHE C  66
LEU C  87
1.66A19.09
3WL  C 401 (-3.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
HIS C 164
VAL C  13
LEU C  30
1.23A21.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLN D 244
VAL D 247
LEU D 262
THR D 225
THR D 226
1.77A22.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
HIS B 164
VAL B  13
LEU B  30
1.18A21.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
HIS D 164
VAL D  13
LEU D  30
1.16A21.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLN C 244
VAL C 247
LEU C 262
THR C 225
THR C 226
1.69A22.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
GLN C 244
VAL C 247
LEU C 262
THR C 225
THR C 226
1.73A19.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6m2q 3CL PROTEASE
(SARS-CoV-2)		3 / 3
HIS A 164
VAL A  13
LEU A  30
1.19A21.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 10
HIS A  41
HIS A 164
VAL A  42
PHE A  66
LEU A  87
1.67A19.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 131
VAL A 128
GLY A 179
VAL A 182
LEU A 241
1.31A14.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ASN A 312
VAL A 128
LEU A 247
THR A 248
THR A 246
1.59A14.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6m71 NSP12
NSP7
(SARS-CoV-2)		3 / 3
HIS A 439
VAL C  11
LEU C  40
0.86A14.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6m71 NSP12
(SARS-CoV-2)		3 / 3
HIS A 810
VAL A 605
LEU A 614
0.99A14.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 638
VAL A 693
GLY A 485
VAL A 476
THR A 586
1.68A14.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU A 366
HIS A 381
GLY A 337
VAL A 338
LEU B  95
1.57A14.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU B  98
VAL A 341
GLY A 385
VAL A 342
LEU B 117
1.49A22.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6m71 NSP12
(SARS-CoV-2)		4 / 4
HIS A 613
GLU A 610
HIS A 752
LEU A 749
1.52A14.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 247
GLY A 179
VAL A 182
VAL A 128
LEU A 241
1.52A14.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ASN B 317
GLN B 314
LEU C 861
THR C 734
THR C 859
1.45A11.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ASN B 317
ILE B 312
LEU C 861
THR C 734
THR C 859
1.73A11.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6vww URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ASN A  75
PHE A 330
VAL A 295
LEU A 298
THR A 196
1.25A22.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6vww URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
HIS A  96
VAL A  54
LEU A  58
1.07A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		5 / 12
LEU A  93
HIS A  86
GLY A  79
VAL A  96
LEU A  43
1.65A
None
None
SO4  A 201 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		5 / 12
LEU B  12
VAL B  16
VAL B 155
VAL B 151
LEU B 126
1.19A
None
None
SO4  B 204 (-3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A 155
LEU A 164
1.27A
None
SO4  A 203 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL B  16
PHE B 168
VAL B 151
LEU B 126
PRO B 136
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A 155
LEU A 126
1.22A
None
SO4  A 203 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		5 / 12
LEU B  93
HIS B  86
GLY B  79
VAL B  96
LEU B  43
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		3 / 3
HIS B 138
VAL B 155
LEU B 126
1.20A
None
SO4  B 204 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		5 / 12
LEU A  12
VAL A  16
VAL A 155
VAL A 151
LEU A 126
1.19A
None
None
SO4  A 203 (-4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL A 144
PHE A 168
VAL A  16
LEU A 126
PRO A 136
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL A  16
PHE A 168
VAL A 151
LEU A 126
PRO A 136
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		3 / 3
HIS B 138
VAL B 155
LEU B 164
1.24A
None
SO4  B 204 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ASN A 317
GLN A 314
LEU B 861
THR B 734
THR B 859
1.58A11.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE B 882
HIS B1064
PHE B 898
LEU B1049
THR B1066
1.48A11.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ASN B 317
ILE B 312
LEU C 861
THR C 734
THR C 859
1.73A11.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ASN C 317
GLN C 314
LEU A 861
THR A 734
THR A 859
1.59A11.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w02 NSP3
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A 155
LEU A 164
1.19A22.02
None
APR  A 201 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 10
GLN A   6
PHE A  48
LEU A  41
THR A  42
THR A  13
1.64A15.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 12
ASN C 422
VAL C 512
VAL C 433
LEU C 425
PRO C 463
1.75A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w4h NSP16
(SARS-CoV-2)		5 / 12
VAL A6882
PHE A7048
VAL A6842
THR A6993
PRO A6805
1.58A22.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
HIS A6917
VAL A6894
LEU A6909
1.39A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
VAL A6882
PHE A7048
VAL A6842
THR A6993
PRO A6805
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
HIS A6867
VAL A6859
LEU A6887
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A  58
HIS A 164
GLY A  79
VAL A  77
VAL A  42
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
HIS A  41
HIS A 164
VAL A  42
PHE A  66
LEU A  87
1.68A19.09
X77  A 401 (-3.2A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
HIS A 164
VAL A  13
LEU A  30
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A 155
LEU A 164
1.20A
None
AMP  A 201 ( 4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A  12
VAL A  16
VAL A 155
VAL A 151
LEU A 126
1.32A
None
None
AMP  A 201 ( 4.4A)
None
AMP  A 201 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		3 / 3
HIS B 138
VAL B  95
LEU B 127
1.48A22.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		3 / 3
HIS B  91
VAL B 147
LEU B 122
1.63A22.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A  93
HIS A  86
GLY A  79
VAL A  96
LEU A  43
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A  93
HIS A  86
GLY A  78
VAL A  96
LEU A  43
1.76A22.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		3 / 3
HIS B 119
VAL B  30
LEU B 123
1.64A22.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A 155
LEU A 126
1.40A22.67
None
AMP  A 201 ( 4.4A)
AMP  A 201 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLN A 118
VAL A  34
VAL A  95
LEU A 122
THR A 149
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A  95
LEU A 127
1.45A22.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		3 / 3
HIS B 138
VAL B 155
LEU B 164
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B  12
VAL B  16
VAL B 155
VAL B 151
LEU B 126
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B  93
HIS B  86
GLY B  79
VAL B  96
LEU B  43
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		3 / 3
HIS B 138
VAL B 155
LEU B 126
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B  93
HIS B  86
GLY B  78
VAL B  96
LEU B  43
1.80A22.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w75 NSP16
(SARS-CoV-2)		3 / 3
HIS A6867
VAL C7092
LEU A6909
1.10A20.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w75 NSP16
(SARS-CoV-2)		3 / 3
HIS C6867
VAL C6859
LEU C6887
1.31A20.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w75 NSP16
(SARS-CoV-2)		5 / 12
VAL C6882
PHE C7048
VAL C6842
THR C6993
PRO C6805
1.58A20.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w75 NSP16
(SARS-CoV-2)		3 / 3
HIS A6867
VAL A6859
LEU A6887
1.34A20.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w75 NSP16
(SARS-CoV-2)		3 / 3
HIS C6917
VAL C6894
LEU C6909
1.22A20.54
FMT  C7113 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w75 NSP16
(SARS-CoV-2)		3 / 3
HIS A6917
VAL A6894
LEU A6909
1.24A20.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w75 NSP16
(SARS-CoV-2)		3 / 3
HIS C6867
VAL A7092
LEU C6909
1.05A20.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w75 NSP16
(SARS-CoV-2)		5 / 12
VAL A6882
PHE A7048
VAL A6842
THR A6993
PRO A6805
1.58A20.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
HIS A 255
VAL A 303
LEU A 253
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
LEU C 211
VAL C 303
GLY C 298
THR C 119
THR C 115
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
HIS B 175
VAL B 205
LEU B 178
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
LEU B 211
VAL B 303
GLY B 298
THR B 119
THR B 115
1.65A
None
None
None
None
CL  B 502 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 211
VAL A 303
GLY A 298
THR A 119
THR A 115
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
HIS A 175
VAL A 205
LEU A 178
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
LEU C 289
HIS C 272
VAL C  98
LEU C 118
THR C 115
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
HIS C 175
VAL C 205
LEU C 178
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wcf NSP3
(SARS-CoV-2)		5 / 12
LEU A  12
VAL A  16
VAL A 155
VAL A 151
LEU A 126
1.16A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wcf NSP3
(SARS-CoV-2)		3 / 3
HIS A  94
VAL A 147
LEU A 122
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wcf NSP3
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A 155
LEU A 164
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wcf NSP3
(SARS-CoV-2)		5 / 12
VAL A  16
PHE A 168
VAL A 151
LEU A 126
PRO A 136
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wcf NSP3
(SARS-CoV-2)		5 / 12
LEU A  93
HIS A  86
GLY A  79
VAL A  96
LEU A  43
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wcf NSP3
(SARS-CoV-2)		5 / 12
VAL A 144
PHE A 168
VAL A  16
LEU A 126
PRO A 136
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wcf NSP3
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A 155
LEU A 126
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wen NSP3
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A 155
LEU A 164
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wen NSP3
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A 155
LEU A 126
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wen NSP3
(SARS-CoV-2)		5 / 12
LEU A  93
HIS A  86
GLY A  79
VAL A  96
LEU A  43
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wen NSP3
(SARS-CoV-2)		5 / 12
LEU A  12
VAL A  16
VAL A 155
VAL A 151
LEU A 126
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wen NSP3
(SARS-CoV-2)		3 / 3
HIS A  94
VAL A 147
LEU A 122
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wey NSP3
(SARS-CoV-2)		5 / 12
ASN A 244
GLN A 266
HIS A 249
HIS A 298
PRO A 278
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wey NSP3
(SARS-CoV-2)		3 / 3
HIS A 342
VAL A 359
LEU A 368
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wey NSP3
(SARS-CoV-2)		5 / 12
LEU A 297
HIS A 290
GLY A 283
VAL A 300
LEU A 247
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wey NSP3
(SARS-CoV-2)		3 / 3
HIS A 342
VAL A 359
LEU A 330
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wey NSP3
(SARS-CoV-2)		5 / 12
LEU A 216
VAL A 220
VAL A 359
VAL A 355
LEU A 330
1.11A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
HIS A6867
VAL C7092
LEU A6909
1.14A
None
FMT  C7107 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
HIS C6867
VAL A7092
LEU C6909
1.13A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
VAL C6882
PHE C7048
VAL C6842
THR C6993
PRO C6805
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
HIS A6917
VAL A6894
LEU A6909
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
VAL A6882
PHE A7048
VAL A6842
THR A6993
PRO A6805
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
HIS A6867
VAL A6859
LEU A6887
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
HIS C6867
VAL C6859
LEU C6887
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wkq NSP16
(SARS-CoV-2)		3 / 3
HIS C6917
VAL C6894
LEU C6909
1.22A
FMT  C7108 ( 4.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wkq NSP16
(SARS-CoV-2)		5 / 12
VAL A6882
PHE A7048
VAL A6842
THR A6993
PRO A6805
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wkq NSP16
(SARS-CoV-2)		3 / 3
HIS A6867
VAL A6859
LEU A6887
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wkq NSP16
(SARS-CoV-2)		5 / 12
VAL C6882
PHE C7048
VAL C6842
THR C6993
PRO C6805
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wkq NSP16
(SARS-CoV-2)		3 / 3
HIS A6917
VAL A6894
LEU A6909
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wkq NSP16
(SARS-CoV-2)		3 / 3
HIS A6867
VAL C7092
LEU A6909
1.09A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wkq NSP16
(SARS-CoV-2)		3 / 3
HIS C6867
VAL A7092
LEU C6909
1.11A
None
NA  A7102 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wkq NSP16
(SARS-CoV-2)		3 / 3
HIS C6867
VAL C6859
LEU C6887
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ASN B  75
GLN B 347
PHE B 330
LEU B 298
THR B 196
1.75A23.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
HIS B  96
VAL B  54
LEU B  58
1.11A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
HIS A  96
VAL A  54
LEU A  58
1.10A
None
EDO  A 403 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ASN A  75
GLN A 347
PHE A 330
LEU A 298
THR A 196
1.78A23.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A  58
HIS A 164
GLY A  79
VAL A  77
VAL A  42
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
HIS A  41
HIS A 164
VAL A  42
PHE A  66
LEU A  87
1.63A19.09
U5G  A 401 (-3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
HIS A 164
VAL A 148
PHE A 159
LEU A 177
THR A 175
1.67A19.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
HIS A 164
VAL A  13
LEU A  30
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A  93
HIS A  86
GLY A  79
VAL A  96
LEU A  43
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
HIS B 138
VAL B 155
LEU B 126
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
HIS C 138
VAL C 155
LEU C 164
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A  12
VAL A  16
VAL A 155
VAL A 151
LEU A 126
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A 155
LEU A 126
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU B  12
VAL B  16
VAL B 155
VAL B 151
LEU B 126
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU D  12
VAL D  16
VAL D 155
VAL D 151
LEU D 126
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
HIS D 138
VAL D 155
LEU D 126
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A 155
LEU A 164
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
HIS B 138
VAL B 155
LEU B 164
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU C  12
VAL C  16
VAL C 155
VAL C 151
LEU C 126
1.23A
None
None
None
None
APR  C 201 (-4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU D  93
HIS D  86
GLY D  79
VAL D  96
LEU D  43
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
HIS C 138
VAL C 155
LEU C 126
1.30A
None
None
APR  C 201 (-4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
HIS D 138
VAL D 155
LEU D 164
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
VAL A6882
PHE A7048
VAL A6842
THR A6993
PRO A6805
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wqd NSP8
(SARS-CoV-2)		5 / 12
VAL D 130
VAL D 159
VAL D 131
THR D 137
THR D 141
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wqd NSP8
(SARS-CoV-2)		5 / 12
ASN D 105
VAL D 130
VAL D 131
THR D 137
THR D 141
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wqd NSP8
(SARS-CoV-2)		5 / 12
ASN B 105
VAL B 130
VAL B 131
THR B 137
THR B 141
1.78A
EDO  B 301 (-3.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
HIS A 164
VAL A  13
LEU A  30
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
HIS A  41
HIS A 164
VAL A  42
PHE A  66
LEU A  87
1.61A19.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
LEU A 211
VAL A 303
GLY A 298
THR A 119
THR A 115
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6wrh PEPTIDASE C16
(SARS-CoV-2)		3 / 3
HIS A 175
VAL A 205
LEU A 178
1.36A
PO4  A 504 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6xez NSP12
NSP7
(SARS-CoV-2)		3 / 3
HIS A 439
VAL C  11
LEU C  40
0.86A14.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL A  73
GLY A 120
VAL A  18
LEU A  75
THR A  93
1.77A18.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.75A21.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
HIS A  41
HIS A 164
VAL A  42
PHE A  66
LEU A  87
1.67A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
HIS A 163
VAL A  20
LEU A  27
1.58A18.99
DMS  A 405 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.74A18.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
HIS A 164
VAL A  13
LEU A  30
1.22A18.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
TRP B 154
ASN B 118
GLN A  31
LEU B 122
THR B 123
1.64A18.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
TRP D 154
ASN D 118
GLN C  31
LEU D 122
THR D 123
1.45A18.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ASN A 422
VAL A 512
VAL A 433
LEU A 425
PRO A 463
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ASN E 422
VAL E 512
VAL E 433
LEU E 425
PRO E 463
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
HIS A 164
VAL A  13
LEU A  30
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
HIS A  41
HIS A 164
VAL A  42
PHE A  66
LEU A  87
1.64A19.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ASN E 422
VAL E 512
VAL E 433
LEU E 425
PRO E 463
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ASN A 422
VAL A 512
VAL A 433
LEU A 425
PRO A 463
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
HIS A 164
VAL A  13
LEU A  30
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
HIS A  41
HIS A 164
VAL A  42
PHE A  66
LEU A  87
1.61A19.08
PK8  A 401 (-3.2A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E  93
HIS E  86
GLY E  79
VAL E  96
LEU E  43
1.62A
None
None
EPE  E 203 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B  12
VAL B  16
VAL B 155
VAL B 151
LEU B 126
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLN B 118
VAL B  34
VAL B  95
LEU B 122
THR B 149
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D  12
VAL D  16
VAL D 155
VAL D 151
LEU D 126
1.27A
None
None
EDO  D 208 ( 4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A 155
LEU A 126
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C  12
VAL C  16
VAL C 155
VAL C 151
LEU C 126
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS B 138
VAL B 155
LEU B 164
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A  12
VAL A  16
VAL A 155
VAL A 151
LEU A 126
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS C 138
VAL C 155
LEU C 126
1.35A
EDO  C 208 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS E 138
VAL E 155
LEU E 126
1.25A
None
EDO  E 205 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS D 138
VAL D 155
LEU D 126
1.37A
EDO  D 204 (-4.1A)
EDO  D 208 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D  93
HIS D  86
GLY D  78
VAL D  96
LEU D  43
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A  93
HIS A  86
GLY A  79
VAL A  96
LEU A  43
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS B 138
VAL B 155
LEU B 126
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D  93
HIS D  86
GLY D  79
VAL D  96
LEU D  43
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS D 138
VAL D 155
LEU D 164
1.26A
EDO  D 204 (-4.1A)
EDO  D 208 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E  12
VAL E  16
VAL E 155
VAL E 151
LEU E 126
1.24A
None
None
EDO  E 205 ( 4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS E 138
VAL E 155
LEU E 164
1.21A
None
EDO  E 205 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A 155
LEU A 164
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS C 138
VAL C 155
LEU C 164
1.26A
EDO  C 208 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B  93
HIS B  86
GLY B  79
VAL B  96
LEU B  43
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C  93
HIS C  86
GLY C  79
VAL C  96
LEU C  43
1.61A
None
None
EPE  C 202 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A  93
HIS A  86
GLY A  79
VAL A  96
LEU A  43
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B  12
VAL B  16
VAL B 155
VAL B 151
LEU B 126
1.22A
None
None
None
None
APR  B 201 (-4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS E 138
VAL E 155
LEU E 126
1.26A
None
APR  E 201 ( 4.9A)
APR  E 201 (-4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A 155
LEU A 164
1.28A
EDO  A 204 ( 4.0A)
APR  A 201 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E  12
VAL E  16
VAL E 155
VAL E 151
LEU E 126
1.27A
None
None
APR  E 201 ( 4.9A)
None
APR  E 201 (-4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A  12
VAL A  16
VAL A 155
VAL A 151
LEU A 126
1.24A
None
None
APR  A 201 ( 4.8A)
None
APR  A 201 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A 155
LEU A 126
1.33A
EDO  A 204 ( 4.0A)
APR  A 201 ( 4.8A)
APR  A 201 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D  93
HIS D  86
GLY D  78
VAL D  96
LEU D  43
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E  93
HIS E  86
GLY E  79
VAL E  96
LEU E  43
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS C 138
VAL C 155
LEU C 126
1.34A
None
APR  C 201 ( 4.9A)
APR  C 201 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS E 138
VAL E 155
LEU E 164
1.24A
None
APR  E 201 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C  12
VAL C  16
VAL C 155
VAL C 151
LEU C 126
1.24A
None
None
APR  C 201 ( 4.9A)
None
APR  C 201 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS D 138
VAL D 155
LEU D 164
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B  93
HIS B  86
GLY B  78
VAL B  96
LEU B  43
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS B 138
VAL B 155
LEU B 126
1.32A
None
None
APR  B 201 (-4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS C 138
VAL C 155
LEU C 164
1.29A
None
APR  C 201 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D  93
HIS D  86
GLY D  79
VAL D  96
LEU D  43
1.54A
None
None
EDO  D 203 (-3.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C  93
HIS C  86
GLY C  79
VAL C  96
LEU C  43
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D  12
VAL D  16
VAL D 155
VAL D 151
LEU D 126
1.25A
None
None
None
None
APR  D 201 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A  93
HIS A  86
GLY A  78
VAL A  96
LEU A  43
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLN B 118
VAL B  34
VAL B  95
LEU B 122
THR B 149
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B  93
HIS B  86
GLY B  79
VAL B  96
LEU B  43
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS B 138
VAL B 155
LEU B 164
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS D 138
VAL D 155
LEU D 126
1.34A
None
None
APR  D 201 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS B 138
VAL B 155
LEU B 126
1.33A
EDO  B 204 ( 4.6A)
EDO  B 202 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C  12
VAL C  16
VAL C 155
VAL C 151
LEU C 126
1.23A
None
None
EDO  C 206 ( 4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS C 138
VAL C 155
LEU C 126
1.34A
None
EDO  C 206 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A 155
LEU A 164
1.26A
EDO  A 205 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLN B 118
VAL B  34
VAL B  95
LEU B 122
THR B 149
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS B 138
VAL B 155
LEU B 164
1.27A
EDO  B 204 ( 4.6A)
EDO  B 202 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS C 138
VAL C 155
LEU C 164
1.26A
None
EDO  C 206 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A  93
HIS A  86
GLY A  79
VAL A  96
LEU A  43
1.61A
None
None
EDO  A 204 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
HIS A 138
VAL A 155
LEU A 126
1.28A
EDO  A 205 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C  93
HIS C  86
GLY C  79
VAL C  96
LEU C  43
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ASN B  40
GLN B  62
HIS B  45
HIS B  94
PRO B  74
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A  12
VAL A  16
VAL A 155
VAL A 151
LEU A 126
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B  93
HIS B  86
GLY B  79
VAL B  96
LEU B  43
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B  12
VAL B  16
VAL B 155
VAL B 151
LEU B 126
1.25A
None
None
EDO  B 202 (-4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		7bqy MAIN PROTEASE
(SARS-CoV-2)		3 / 3
HIS A 164
VAL A  13
LEU A  30
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 10
HIS A  41
HIS A 164
VAL A  42
PHE A  66
LEU A  87
1.64A19.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7btf NSP12
(SARS-CoV-2)		5 / 12
LEU A 131
VAL A 128
GLY A 179
VAL A 182
LEU A 241
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7btf NSP12
(SARS-CoV-2)		5 / 12
LEU A 638
VAL A 693
GLY A 485
VAL A 476
THR A 586
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7btf NSP8
(SARS-CoV-2)		5 / 12
ASN D 105
VAL D 130
VAL D 131
THR D 137
THR D 141
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7btf NSP12
(SARS-CoV-2)		5 / 12
ASN A 312
VAL A 128
LEU A 247
THR A 248
THR A 246
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU B 117
VAL A 330
GLY A 385
VAL B 115
LEU B 103
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU A 366
HIS A 381
GLY A 337
VAL A 338
LEU B  95
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
VAL A 330
VAL A 398
VAL B 115
THR B 123
THR B 124
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU A 329
VAL A 330
VAL A 341
THR B 124
THR B 123
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		7btf NSP12
NSP7
(SARS-CoV-2)		3 / 3
HIS A 439
VAL C  11
LEU C  40
0.86A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		7btf NSP12
(SARS-CoV-2)		3 / 3
HIS A 810
VAL A 605
LEU A 614
0.93A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7btf NSP12
(SARS-CoV-2)		5 / 12
LEU A 245
GLY A 179
VAL A 128
LEU A 212
THR A 123
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU B  98
VAL A 341
GLY A 385
VAL A 342
LEU B 117
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7btf NSP8
(SARS-CoV-2)		5 / 12
LEU D 128
VAL D 130
VAL D 131
THR D 137
THR D 141
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		3 / 3
HIS A 164
VAL A  13
LEU A  30
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 10
HIS A  41
HIS A 164
VAL A  42
PHE A  66
LEU A  87
1.67A19.09
JRY  A 401 (-3.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 12
TRP D 154
ASN D 118
GLN C  31
LEU D 122
THR D 123
1.36A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
LEU A 131
VAL A 128
GLY A 179
VAL A 182
LEU A 241
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
HIS A 810
VAL A 605
LEU A 614
0.95A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
LEU A 638
VAL A 693
GLY A 485
VAL A 476
THR A 586
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU B  98
VAL A 341
GLY A 385
VAL A 342
LEU B 117
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ASN A 312
VAL A 128
LEU A 247
THR A 248
THR A 246
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		7bv1 NSP12
NSP7
(SARS-CoV-2)		3 / 3
HIS A 439
VAL C  11
LEU C  40
0.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU A 329
VAL A 330
VAL A 341
THR B 124
THR B 123
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU B 117
VAL A 330
GLY A 385
VAL B 115
LEU B 103
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU B 117
VAL A 330
GLY A 385
VAL B 115
LEU B 103
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ASN A 909
HIS A 882
LEU A 869
THR A 870
PRO A 868
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		7bv2 NSP12
NSP7
(SARS-CoV-2)		3 / 3
HIS A 439
VAL C  11
LEU C  40
0.96A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
LEU A 247
GLY A 179
VAL A 182
VAL A 128
LEU A 241
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU B  98
VAL A 341
GLY A 385
VAL A 342
LEU B 117
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU A 329
VAL A 330
VAL A 341
THR B 124
THR B 123
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
LEU A 131
VAL A 128
GLY A 179
VAL A 182
LEU A 241
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
HIS A 810
VAL A 605
LEU A 614
0.97A
None