Ligand ID: BEP


Drugbank ID:
DB01244
(Bepridil)


Indication:
For the treatment of hypertension, and chronic stable angina (classic effort-associated angina).

Get human targets for BEP in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'BEP' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		5r83 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 11
PHE A  66
LEU A  87
MET A  82
GLU A  55
LEU A  57
1.62A18.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 11
PHE A  66
LEU A  87
MET A  82
GLU A  55
LEU A  57
1.64A19.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 12
ILE F1169
PHE F 970
PHE D 970
LEU F 959
LEU D 959
1.49A24.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6lzg ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLN B 493
GLU B 406
GLU A  37
ASP A  38
1.67A22.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6m17 ACE2
RECEPTOR BINDING
DOMAIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
PRO D 389
GLU D  37
GLU F 406
ASP F 405
1.55A11.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 11
PHE C 219
LEU C 268
GLU C 288
LEU C 286
LEU C 287
1.66A18.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6m3m NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE B  67
ILE B 132
LEU B  65
LEU B 162
GLU B  63
1.60A17.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6m3m NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
PRO B  68
GLU B  63
ASP B  64
ARG B  90
1.50A21.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m71 NSP12
(SARS-CoV-2)		5 / 11
ILE A 145
LEU A 212
MET A 124
LEU A 207
LEU A 241
1.65A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  90
LEU B 117
MET A 666
1.56A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 11
LEU C  55
MET C  52
LEU D 103
VAL C  22
LEU C  71
1.72A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
LEU B 117
MET A 666
MET B  94
1.73A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ALA A 702
PHE A 782
LEU A 749
PHE A 745
LEU A 727
1.41A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 779
PHE A 753
MET A 755
LEU A 786
PHE A 694
1.61A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 11
ILE D 119
LEU C  14
MET C  62
LEU D  95
LEU C  13
1.61A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 589
LEU A 758
ILE A 757
VAL A 587
MET A 601
1.78A6.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 11
ILE B 107
LEU A 270
VAL A 341
LEU A 387
LEU B 122
1.78A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  90
MET A 666
LEU B 117
1.66A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 888
LEU A 891
MET A 855
ILE A 856
VAL A 860
1.51A6.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 757
PHE A 694
PHE A 753
LEU A 749
MET A 755
1.60A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m71 NSP12
(SARS-CoV-2)		5 / 11
LEU A 630
MET A 633
LEU A 308
VAL A 785
LEU A 731
1.64A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
(SARS-CoV-2)		6 / 12
ALA A 777
PHE A 782
MET A 755
LEU A 708
LEU A 707
PHE A 745
1.68A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 11
ILE B 107
LEU B 103
VAL A 330
LEU B  91
LEU B  95
1.24A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA C  48
ILE C  39
LEU D 122
LEU C  56
LEU D 103
1.52A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 11
ILE D 119
LEU C  28
LEU C  14
MET C  62
LEU C  13
1.69A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA C  65
LEU C  71
PHE D  92
LEU C  56
LEU C  60
1.69A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 757
MET A 794
PHE A 753
LEU A 749
MET A 755
1.36A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA A 376
LEU A 401
LEU B 117
MET A 666
MET B  94
1.60A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 11
LEU C  55
MET C  52
LEU D 103
VAL C  22
LEU D  95
1.80A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE C 201
ILE C 231
LEU C 229
VAL C 130
LEU C 241
1.53A7.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
GLN B 644
GLU B 619
ASP B 614
ARG B 646
1.73A7.84
NAG  B1303 ( 4.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6vww URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ILE A 306
LEU A 228
PHE A 233
LEU A 251
MET A 210
1.45A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE C 106
ILE C 235
LEU C 118
LEU C 242
LEU C 241
1.62A7.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE C 927
ILE C 931
LEU C1063
ILE C 818
GLU C 819
1.65A5.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
GLN C 563
PRO C 561
GLU A 224
ASP A  40
1.64A7.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE C 927
ILE C 931
LEU C1063
ILE C 818
GLU C 819
1.60A5.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE C 201
ILE C 231
LEU C 229
VAL C 130
LEU C 241
1.43A7.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		4 / 8
PRO A  67
GLU A  62
ASP A  63
ARG A  89
1.28A20.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
PHE A  66
ILE A 131
LEU A  64
LEU A 161
GLU A  62
1.56A18.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE B 264
ILE B 281
LEU B 246
VAL B 295
LEU B 215
1.48A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ILE A 323
LEU A 298
ILE A 306
GLU A 305
VAL A 321
1.29A14.36
None
None
None
EDO  A 411 (-4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 12
PHE C 377
PHE C 374
LEU C 513
LEU C 425
PHE C 400
1.68A18.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 12
PHE C 377
LEU C 513
PHE C 429
LEU C 425
PHE C 400
1.76A18.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w4h NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
MET A6982
LEU A6959
LEU A6857
1.42A19.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w4h NSP16
(SARS-CoV-2)		5 / 11
ILE A6951
LEU A6883
MET A6982
LEU A6855
LEU A6852
1.47A19.93
None
None
None
BDF  A7105 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
MET A6982
LEU A6959
LEU A6857
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A7005
LEU A6959
LEU A6978
MET A6982
1.76A22.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6925
LEU A6857
LEU A6887
LEU A6883
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
LEU A6959
PHE A6985
MET A6982
1.80A22.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		6 / 12
ALA A6966
ILE A7005
LEU A6959
LEU A6981
MET A6982
LEU A6978
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A7005
LEU A6848
LEU A7050
LEU A6893
LEU A6887
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A6955
LEU A6959
MET A6982
LEU A6855
LEU A6852
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A6955
LEU A6959
MET A6982
LEU A6855
LEU A6857
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
LEU A6978
LEU A6959
MET A6982
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A7005
LEU A6959
LEU A6978
MET A6982
1.75A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
MET A6982
LEU A6959
LEU A6857
1.40A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 11
ILE A7005
LEU A6848
LEU A7050
LEU A6893
LEU A6887
1.78A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6925
LEU A6857
LEU A6893
LEU A6883
1.77A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
LEU A6978
LEU A6959
MET A6982
1.49A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6925
LEU C6857
LEU C6887
LEU C6883
1.64A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6925
LEU C6857
LEU C6893
LEU C6883
1.76A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6926
MET C6982
LEU C6959
LEU C6857
1.39A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6925
LEU A6857
LEU A6887
LEU A6883
1.64A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6926
PHE C7003
LEU C6978
LEU C6959
1.79A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C7005
LEU C6959
MET C6982
LEU C6978
1.53A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 11
ILE A6955
LEU A6959
MET A6982
LEU A6855
LEU A6857
1.73A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6926
LEU C6978
LEU C6959
MET C6982
1.46A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 11
ILE A6951
LEU A6883
MET A6982
LEU A6855
LEU A6852
1.48A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 11
ILE C6955
LEU C6959
MET C6982
LEU C6855
LEU C6857
1.74A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C7005
LEU C6959
LEU C6978
MET C6982
1.73A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 11
ILE C7005
LEU C6848
LEU C7050
LEU C6893
LEU C6887
1.77A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A7005
LEU A6959
MET A6982
LEU A6978
1.56A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 11
ILE C6951
LEU C6883
MET C6982
LEU C6855
LEU C6852
1.44A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 147
ILE A 151
LEU A 172
MET A 169
CYH A 260
1.59A12.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
PHE C 147
ILE C 151
LEU C 172
MET C 169
CYH C 260
1.67A12.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
PHE B 147
ILE B 151
LEU B 172
MET B 169
CYH B 260
1.56A12.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
ALA A  30
PHE A  56
LEU A 106
LEU A  88
PHE A  90
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA B 110
ILE A  68
LEU B 103
LEU B  91
LEU A  59
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA A  65
LEU A  71
PHE B  92
LEU A  56
LEU A  60
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA A  48
ILE A  39
LEU B 122
LEU A  56
LEU B 103
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
PHE B  92
ILE B 107
LEU B  95
MET A  52
CYH A  32
1.74A22.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE A  39
LEU A  56
MET A  52
LEU A  13
MET B  90
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE C 286
ILE D 320
LEU D 331
LEU C 352
MET D 322
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE E 286
ILE F 320
LEU F 331
LEU E 352
MET F 322
1.49A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE D 286
LEU D 353
ILE D 292
GLU D 290
VAL D 270
1.56A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE F 286
ILE E 320
LEU E 331
LEU F 352
MET E 322
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE F 286
LEU F 353
ILE F 292
GLU F 290
VAL F 270
1.59A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE C 307
ILE C 337
LEU C 339
MET D 322
LEU C 291
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE D 286
ILE C 320
LEU C 331
LEU D 352
MET C 322
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE C 286
LEU C 353
ILE C 292
GLU C 290
VAL C 270
1.61A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE E 286
ILE F 320
LEU F 331
LEU E 352
MET F 322
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE B 286
ILE A 320
LEU A 331
LEU B 352
MET A 322
1.53A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE A 286
ILE B 320
LEU B 331
LEU A 352
MET B 322
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE B 286
LEU B 353
ILE B 292
GLU B 290
VAL B 270
1.56A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE D 286
ILE C 320
LEU C 331
LEU D 352
MET C 322
1.49A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE E 286
LEU E 353
ILE E 292
GLU E 290
VAL E 270
1.58A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE B 286
ILE A 320
LEU A 331
LEU B 352
MET A 322
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE A 286
ILE B 320
LEU B 331
LEU A 352
MET B 322
1.46A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE F 286
ILE E 320
LEU E 331
LEU F 352
MET E 322
1.60A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE A 286
LEU A 353
ILE A 292
GLU A 290
VAL A 270
1.62A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE C 286
ILE D 320
LEU D 331
LEU C 352
MET D 322
1.52A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		6 / 12
ALA A6966
ILE A7005
LEU A6959
LEU A6981
MET A6982
LEU A6978
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6926
MET C6982
LEU C6959
LEU C6857
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C7005
LEU C6959
MET C6982
LEU C6978
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE C6955
LEU C6959
MET C6982
LEU C6855
LEU C6857
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A6955
LEU A6959
MET A6982
LEU A6855
LEU A6857
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE C6951
LEU C6883
MET C6982
LEU C6855
LEU C6852
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE C7005
LEU C6848
LEU C7050
LEU C6893
LEU C6887
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C7005
LEU C6959
LEU C6978
MET C6982
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6926
LEU C6978
LEU C6959
MET C6982
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A6951
LEU A6883
MET A6982
LEU A6855
LEU A6852
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A7005
LEU A6848
LEU A7050
LEU A6893
LEU A6887
1.78A
None
None
FMT  A7107 (-4.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6925
LEU A6857
LEU A6887
LEU A6883
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
LEU A6978
LEU A6959
MET A6982
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
MET A6982
LEU A6959
LEU A6857
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6997
ILE A7035
LEU A7042
LEU A6848
MET A6840
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6925
LEU C6857
LEU C6887
LEU C6883
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE D  66
ILE D 131
LEU D  64
LEU D 161
GLU D  62
1.62A18.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
PRO C  67
GLU C  62
ASP C  63
ARG C  89
1.42A21.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
PRO B  67
GLU B  62
ASP B  63
ARG B  89
1.42A21.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE B  66
ILE B 131
LEU B  64
LEU B 161
GLU B  62
1.51A18.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
PRO D  67
GLU D  62
ASP D  63
ARG D  89
1.56A21.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE C  66
ILE C 131
LEU C  64
LEU C 161
GLU C  62
1.61A18.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C7005
LEU C6959
LEU C6978
MET C6982
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6925
LEU C6857
LEU C6887
LEU C6883
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6926
MET C6982
LEU C6959
LEU C6857
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A7005
LEU A6959
LEU A6978
MET A6982
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6926
LEU C6978
LEU C6959
MET C6982
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 11
ILE A7005
LEU A6848
LEU A7050
LEU A6893
LEU A6887
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6925
LEU A6857
LEU A6887
LEU A6883
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 11
ILE C7005
LEU C6848
LEU C7050
LEU C6893
LEU C6887
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 11
ILE C6951
LEU C6883
MET C6982
LEU C6855
LEU C6852
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C7005
LEU C6959
MET C6982
LEU C6978
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 11
ILE A6951
LEU A6883
MET A6982
LEU A6855
LEU A6852
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 11
ILE C6955
LEU C6959
MET C6982
LEU C6855
LEU C6857
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
MET A6982
LEU A6959
LEU A6857
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A7005
LEU A6959
MET A6982
LEU A6978
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA A6997
ILE A7035
LEU A7042
LEU A6848
MET A6840
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
LEU A6978
LEU A6959
MET A6982
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 11
ILE A6955
LEU A6959
MET A6982
LEU A6855
LEU A6857
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ILE B 323
LEU B 298
ILE B 306
GLU B 305
VAL B 321
1.35A14.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ILE A 306
LEU A 228
PHE A 233
LEU A 251
MET A 210
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ILE A 323
LEU A 298
ILE A 306
GLU A 305
VAL A 321
1.32A14.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
PHE B 303
ILE B 306
LEU B 298
ILE B 323
VAL B 321
1.49A14.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ILE B 306
LEU B 228
PHE B 233
LEU B 251
MET B 210
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
PHE A 303
ILE A 306
LEU A 298
ILE A 323
VAL A 321
1.45A14.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6925
LEU A6857
LEU A6887
LEU A6883
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
LEU A6978
LEU A6959
MET A6982
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A6955
LEU A6959
MET A6982
LEU A6855
LEU A6857
1.70A
None
None
None
8NK  A7103 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
MET A6982
LEU A6959
LEU A6857
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A7005
LEU A6959
LEU A6978
MET A6982
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A6955
LEU A6959
MET A6982
LEU A6855
LEU A6852
1.80A
None
None
None
8NK  A7103 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A7005
LEU A6848
LEU A7050
LEU A6893
LEU A6887
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A6951
LEU A6883
MET A6982
LEU A6855
LEU A6852
1.43A
None
None
None
8NK  A7103 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A7005
LEU A6959
MET A6982
LEU A6978
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE A  39
MET D  94
LEU A  56
MET A  52
LEU A  13
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 11
PHE B  92
ILE B 107
LEU B  95
MET A  52
LEU A  17
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 11
LEU A  55
MET A  52
LEU B 103
VAL A  22
LEU A  71
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
PHE D  92
ILE D 107
LEU D  95
MET C  52
CYH C  32
1.72A22.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA A  48
ILE A  39
LEU B 122
LEU A  56
LEU B 103
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 11
LEU C  55
MET C  52
LEU D 103
VAL C  22
LEU C  71
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 11
PHE D  92
ILE D 107
LEU D  95
MET C  52
LEU C  17
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA C  48
ILE C  39
LEU D 122
LEU C  56
LEU D 103
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 11
ILE D 119
LEU C  55
MET C  52
LEU D 103
LEU C  71
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE A  39
LEU A  56
MET A  52
LEU A  13
MET B  90
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE C  39
LEU C  56
MET C  52
LEU C  13
MET D  90
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
PHE B  92
ILE B 107
LEU B  95
MET A  52
CYH A  32
1.68A22.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE C  39
MET B  94
LEU C  56
MET C  52
LEU C  13
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE C  39
MET B  94
LEU D  98
LEU C  56
LEU C  13
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE A  39
MET D  94
LEU B  98
LEU A  56
LEU A  13
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
PHE A 147
ILE A 151
LEU A 172
MET A 169
CYH A 260
1.62A12.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ALA C  48
ILE C  39
LEU D 122
LEU C  56
LEU D 103
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU C  13
MET C  52
LEU D 103
VAL C  16
MET D  90
1.63A24.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ILE C  39
MET B  94
LEU D  98
LEU C  56
LEU C  13
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ALA C  65
LEU C  71
PHE D  92
LEU C  13
LEU C  17
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ILE A  39
LEU A  56
MET A  52
LEU A  13
MET B  90
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 11
PHE D  92
ILE D 107
LEU C  60
LEU C  17
LEU C  20
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 11
LEU C  55
MET C  52
LEU D 103
VAL C  22
LEU C  71
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 11
PHE D  92
ILE D 107
LEU D  95
MET C  52
LEU C  17
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ILE C  39
LEU C  56
MET C  52
LEU C  13
MET D  90
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
PHE B  92
ILE B 107
LEU B  95
MET A  52
CYH A  32
1.72A23.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ALA A  48
ILE A  39
LEU B 122
LEU A  56
LEU B 103
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ILE C  39
MET B  94
LEU C  56
MET C  52
LEU C  13
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ILE A  39
MET D  94
LEU B  98
LEU A  56
LEU A  13
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
PHE D  92
ILE D 107
LEU D  95
MET C  52
CYH C  32
1.66A23.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ILE A  39
MET D  94
LEU A  56
MET A  52
LEU A  13
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE E 377
PHE E 374
PHE E 429
LEU E 425
PHE E 400
1.74A
None
DMS  E 901 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 434
LEU A 368
LEU A 387
GLU A 340
VAL A 511
1.53A16.18
None
None
DMS  A 905 ( 4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE A 377
PHE A 374
PHE A 429
LEU A 425
PHE A 400
1.73A
None
DMS  A 901 (-4.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE E 377
PHE E 374
PHE E 429
LEU E 425
PHE E 400
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE E 434
LEU E 368
LEU E 387
GLU E 340
VAL E 511
1.57A16.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 11
LEU A 630
MET A 633
LEU A 308
VAL A 785
LEU A 731
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		4 / 8
MET A 566
GLN A 524
ASP A 523
MET A 519
1.75A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		6 / 12
ALA A 777
PHE A 782
MET A 755
LEU A 708
LEU A 707
PHE A 745
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 12
ILE A 757
PHE A 694
PHE A 753
LEU A 749
MET A 755
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_2
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES
TROPONIN I, CARDIAC
MUSCLE)		7btf NSP12
(SARS-CoV-2)		4 / 4
ARG A 331
ILE A 333
ALA A 379
MET A 380
1.74A2.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 12
ALA A 702
PHE A 782
LEU A 749
PHE A 745
LEU A 727
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7btf NSP12
(SARS-CoV-2)		5 / 12
PHE A 652
ILE A 307
LEU A 351
ILE A 632
GLU A 658
1.66A6.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7btf NSP12
(SARS-CoV-2)		5 / 12
ILE A 145
LEU A 212
MET A 124
LEU A 207
GLU A 180
1.67A6.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7btf NSP12
(SARS-CoV-2)		5 / 12
ILE A 888
LEU A 891
MET A 855
ILE A 856
VAL A 860
1.53A6.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA C  48
ILE C  39
LEU D 122
LEU C  56
LEU D 103
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 11
ILE A 856
LEU A 891
VAL A 848
LEU A 838
LEU A 883
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  94
MET A 666
LEU B 117
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 12
ILE A 779
PHE A 753
MET A 755
LEU A 786
PHE A 694
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 11
ILE D 119
LEU C  14
MET C  62
LEU D  95
LEU C  13
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 11
LEU A 630
MET A 633
LEU A 308
LEU A 731
LEU A 470
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 11
LEU C  55
MET C  52
LEU D 103
VAL C  22
LEU D  95
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 11
ILE A 145
LEU A 212
MET A 124
LEU A 207
LEU A 241
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 12
ALA A 863
ILE A 888
PHE A 881
PHE A 594
MET A 924
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  90
MET A 666
LEU B 117
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7btf NSP12
(SARS-CoV-2)		5 / 12
ILE A 589
LEU A 758
MET A 756
ILE A 757
VAL A 587
1.77A6.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 12
ALA A 688
ILE A 589
PHE A 480
LEU A 575
LEU A 576
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv1 NSP12
(SARS-CoV-2)		6 / 12
ALA A 777
PHE A 782
MET A 755
LEU A 708
LEU A 707
PHE A 745
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 11
ILE B 107
LEU A 270
VAL A 341
LEU A 387
LEU B 122
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
LEU A 630
MET A 633
LEU A 308
VAL A 785
LEU A 731
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ILE A 589
LEU A 758
ILE A 757
VAL A 587
MET A 601
1.78A7.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  94
MET A 666
LEU B 117
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  90
MET A 666
LEU B 117
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA C  48
ILE C  39
LEU D 122
LEU C  56
LEU D 103
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ALA A 702
PHE A 782
LEU A 749
PHE A 745
LEU A 727
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
PHE A 287
LEU A 316
LEU A 241
VAL A 320
GLU A 180
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 11
ILE B 107
LEU B 103
VAL A 330
LEU B  91
LEU B  95
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 11
ILE D 119
LEU C  14
MET C  62
LEU D  95
LEU C  13
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
ILE A 145
LEU A 212
MET A 124
LEU A 207
LEU A 241
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ILE A 779
PHE A 753
MET A 755
LEU A 786
PHE A 694
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ILE A 757
PHE A 694
PHE A 753
LEU A 749
MET A 755
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ILE A 888
LEU A 891
MET A 855
ILE A 856
VAL A 860
1.53A7.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
PHE A 745
LEU A 749
LEU A 707
ILE A 696
VAL A 476
1.54A7.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
MET A 566
GLN A 524
ASP A 523
MET A 519
1.71A10.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 11
ILE B 107
LEU B 103
VAL A 330
LEU B  91
LEU B  95
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_2
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES
TROPONIN I, CARDIAC
MUSCLE)		7bv2 NSP12
(SARS-CoV-2)		4 / 4
ARG A 331
ILE A 333
ALA A 379
MET A 380
1.55A2.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ILE A 757
PHE A 694
PHE A 753
LEU A 749
MET A 755
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  94
MET A 666
LEU B 117
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7bv2 NSP8
(SARS-CoV-2)		5 / 12
ILE B 107
LEU B 103
LEU B  95
ILE B 106
VAL B 115
1.47A17.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ILE A 589
LEU A 758
MET A 756
ILE A 757
VAL A 587
1.76A7.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
ILE A 856
LEU A 891
LEU A 885
VAL A 848
LEU A 838
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		6 / 12
ALA A 777
PHE A 782
MET A 755
LEU A 708
LEU A 707
PHE A 745
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
LEU A 630
MET A 633
LEU A 308
VAL A 785
LEU A 731
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  90
LEU B 117
MET B  94
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
ILE A 145
LEU A 212
MET A 124
LEU A 207
LEU A 241
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ALA A 702
PHE A 782
LEU A 749
PHE A 745
LEU A 727
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ILE A 779
PHE A 753
MET A 755
LEU A 786
PHE A 694
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  90
MET A 666
LEU B 117
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
LEU A 673
LEU A 388
MET A 666
ILE A 539
GLU A 665
1.55A7.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA A 375
MET B  90
LEU A 401
LEU B 117
MET B  94
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ALA A 688
ILE A 589
PHE A 480
LEU A 575
LEU A 576
1.70A
F86  P 102 ( 4.1A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
ILE A 856
LEU A 891
VAL A 848
LEU A 838
LEU A 883
1.59A
None