Ligand ID: AZZ


Drugbank ID:
DB00495
(Zidovudine)


Indication:
Used in combination with other antiretroviral agents for the treatment of human immunovirus (HIV) infections.

Get human targets for AZZ in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'AZZ' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
LEU A  87
HIS A 164
PHE A 181
TYR A  54
1.78A15.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
SER A 113
GLN A 127
VAL A 297
ARG A 298
1.59A15.61
DMS  A 402 ( 4.7A)
DMS  A 402 (-3.4A)
None
DMS  A 402 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
PHE A 140
ARG A 131
GLY A 138
LYS A 137
1.79A15.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
LEU A 250
ILE A 249
HIS A 246
GLY A 109
1.66A15.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
LEU A 250
ILE A 249
HIS A 246
GLY A 109
1.72A18.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
LEU A 167
HIS A 172
PHE A 140
ARG A 131
1.63A18.14
DMS  A 401 ( 4.9A)
ELL  D   3 (-4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		6lzg SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
THR B 430
LEU B 513
TYR B 365
VAL B 524
LEU B 517
1.45A18.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6m03 MAIN PROTEASE
(SARS-CoV-2)		4 / 8
SER A 113
GLN A 127
VAL A 297
ARG A 298
1.51A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
PHE A 140
ARG A 131
GLY A 138
LYS A 137
1.66A17.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
LEU A 167
HIS A 172
PHE A 140
ARG A 131
1.64A17.97
None
ELL  D   3 (-4.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
LEU A 250
ILE A 249
HIS A 246
GLY A 109
1.71A17.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
LEU D 250
ILE D 249
HIS D 246
GLY D 109
1.63A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
PHE B 140
ARG B 131
GLY B 138
LYS B 137
1.77A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
LEU B  87
HIS B 164
PHE B 181
TYR B  54
1.76A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
LEU C 250
ILE C 249
HIS C 246
GLY C 109
1.67A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
PHE A 140
ARG A 131
GLY A 138
LYS A 137
1.68A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
LEU A 250
ILE A 249
HIS A 246
GLY A 109
1.69A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
PHE A 140
ARG A 131
GLY A 138
LYS A 137
1.60A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
LEU A  87
HIS A 164
PHE A 181
TYR A  54
1.76A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
LEU A 167
HIS A 172
PHE A 140
LYS A 137
1.72A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		6m71 NSP7
(SARS-CoV-2)		5 / 12
GLU C  23
TRP C  29
LEU C  14
ARG C  21
MET C  62
1.73A17.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6m71 NSP12
NSP7
(SARS-CoV-2)		4 / 8
LEU C  35
ILE C  39
HIS C  36
PHE A 440
1.76A10.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
LEU A 351
ILE A 632
ARG A 349
GLY A 678
1.75A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
SER A 635
HIS A 642
CYH A 646
ARG A 654
1.30A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
ILE A 864
PHE A 881
TYR A 915
LYS A 906
1.67A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 11
THR C   9
LEU C  14
VAL C  58
MET C  52
LEU D  95
1.75A15.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_B_AZZB1211_1
(DEOXYNUCLEOSIDE
KINASE)		6m71 NSP7
(SARS-CoV-2)		5 / 12
GLU C  23
TRP C  29
LEU C  14
ARG C  21
MET C  62
1.71A17.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
PHE A 429
TYR A 884
ARG A 836
GLY A 839
1.54A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
GLU C 819
SER C 816
GLN C1054
VAL C1033
1.66A17.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
ASN C 969
PHE C 970
GLY A 757
TYR A 756
1.32A20.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 8
LEU A 806
ILE A 882
PHE A 800
TYR C 707
GLY A 798
1.71A17.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6vww URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
GLU A  69
SER A 198
GLN A 160
VAL A 173
1.06A20.50
GOL  A 405 (-4.6A)
GOL  A 405 (-4.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6vxs NSP3
(SARS-CoV-2)		4 / 8
LEU B 109
ILE B 106
GLY B 103
LYS B 102
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
ASN A 928
PHE A 927
ALA A 924
GLY A 799
1.41A20.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 8
LEU C 806
ILE C 882
PHE C 800
TYR B 707
GLY C 798
1.68A17.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
ASN C 928
PHE C 927
ALA C 924
GLY C 799
1.39A20.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
THR A 430
LEU A 513
TYR A 365
VAL A 524
LEU A 517
1.41A16.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 8
LEU B 806
ILE B 882
PHE B 800
TYR A 707
GLY B 798
1.68A17.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
LEU B 228
VAL B 237
ILE B 253
PHE B 222
LEU B 215
1.76A21.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w41 CR3022 FAB LIGHT
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 8
ILE L  28
PHE C 515
TYR L  32
GLY C 431
1.48A13.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		6w4h NSP16
(SARS-CoV-2)		5 / 12
ILE A6838
MET A7045
PHE A7048
GLN A6885
ALA A6881
1.78A20.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A7004
ILE A7005
ARG A7030
GLY A6806
1.78A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A6924
ILE A6925
PHE A6868
ARG A6864
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A6848
ILE A6926
PHE A6868
GLY A6869
1.65A
None
None
None
SAM  A7104 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A7073
ILE A7079
ARG A7077
GLY A7054
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6925
PHE A6985
ARG A7081
GLY A6963
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A6838
MET A7045
PHE A7048
GLN A6885
ALA A6881
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A6924
ILE A6925
PHE A6954
ARG A7081
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
ILE A 136
PHE A 140
TYR A 182
GLY A 149
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
LEU A 250
ILE A 249
HIS A 246
GLY A 109
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		6w6y NSP3
(SARS-CoV-2)		4 / 5
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.75A
None
AMP  A 201 ( 4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU C6848
ILE C6926
PHE C6868
GLY C6869
1.65A13.08
None
None
None
SAM  C7105 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU A6848
ILE A6926
PHE A6868
GLY A6869
1.66A13.08
None
None
None
SAM  A7102 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ILE A6838
MET A7045
PHE A7048
GLN A6885
ALA A6881
1.80A19.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU C7004
ILE C7005
ARG C7030
GLY C6806
1.79A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A6925
PHE A6985
ARG A7081
GLY A6963
1.65A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU C7078
ILE C7069
GLY C7063
LYS C7061
1.70A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		6w75 NSP16
(SARS-CoV-2)		4 / 5
ASN C6975
ALA C6976
GLY C7019
TYR C7020
1.76A12.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 8
SER C6872
HIS D4333
CYH D4330
ARG D4331
1.45A13.08
SAM  C7105 ( 4.4A)
None
ZN  D4401 ( 2.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU C7073
ILE C7079
ARG C7077
GLY C7054
1.19A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		6w75 NSP16
(SARS-CoV-2)		4 / 5
ASN C6975
PHE C6948
ALA C6976
TYR C6979
1.80A12.25
None
FMT  C7115 ( 4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C6925
PHE C6985
ARG C7081
GLY C6963
1.67A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU A6924
ILE A6925
PHE A6868
ARG A6864
1.59A13.08
None
None
None
FMT  A7106 ( 2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A6926
HIS A6867
PHE A6868
ARG A6884
1.74A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
LEU C6924
ILE C6925
PHE C6868
ARG C6864
1.60A13.08
None
None
None
FMT  C7106 ( 2.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C6926
HIS C6867
PHE C6868
ARG C6884
1.74A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		4 / 8
SER A6872
HIS B4333
CYH B4330
ARG B4331
1.48A13.08
SAM  A7102 ( 4.6A)
None
ZN  B4401 ( 2.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		6wen NSP3
(SARS-CoV-2)		4 / 5
ASN A  40
PHE A 132
ALA A  50
GLY A  47
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		6wey NSP3
(SARS-CoV-2)		4 / 5
ASN A 244
PHE A 336
ALA A 254
GLY A 251
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 11
THR A   9
LEU A  14
VAL A  58
MET A  52
LEU B  95
1.74A16.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE A 337
LEU A 353
PHE A 286
ALA B 311
PHE B 314
1.64A
None
None
None
CL  A 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE F 337
LEU F 353
PHE F 286
ALA E 311
PHE E 314
1.62A
None
None
None
CL  F 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE D 337
LEU D 353
PHE D 286
ALA C 311
PHE C 314
1.59A
None
None
None
CL  D 401 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
LEU E 331
ILE E 320
TYR F 333
GLY E 316
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE E 337
LEU E 353
PHE E 286
ALA F 311
PHE F 314
1.59A
None
None
None
CL  E 401 ( 4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE C 337
LEU C 353
PHE C 286
ALA D 311
PHE D 314
1.61A
None
None
None
CL  C 401 ( 3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE B 337
LEU B 353
PHE B 286
ALA A 311
PHE A 314
1.59A
None
None
None
CL  B 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A6848
ILE A6926
PHE A6868
GLY A6869
1.65A
None
None
None
SAH  A7102 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
SER C6872
HIS D4333
CYH D4330
ARG D4331
1.47A18.29
SAH  C7102 (-4.7A)
None
ZN  D4401 (-2.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU C6924
ILE C6925
PHE C6868
ARG C6864
1.61A
None
None
None
FMT  C7103 (-2.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU C7004
ILE C7005
ARG C7030
GLY C6806
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6925
PHE A6985
ARG A7081
GLY A6963
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
SER A6872
HIS B4333
CYH B4330
ARG B4331
1.48A18.29
SAH  A7102 ( 4.6A)
None
ZN  B4401 (-2.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A6924
ILE A6925
PHE A6868
ARG A6864
1.59A
None
None
None
FMT  A7106 (-2.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU C7073
ILE C7079
ARG C7077
GLY C7054
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE C6925
PHE C6985
ARG C7081
GLY C6963
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU C6848
ILE C6926
PHE C6868
GLY C6869
1.65A
None
None
None
SAH  C7102 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU C7078
ILE C7069
GLY C7063
LYS C7061
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
LEU D 139
ILE D  84
TYR D 123
GLY D  69
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
LEU C6848
ILE C6926
PHE C6868
GLY C6869
1.65A
None
None
None
SFG  C7103 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
LEU A6924
ILE A6925
PHE A6868
ARG A6864
1.62A
None
None
None
FMT  A7109 ( 2.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
LEU C7073
ILE C7079
ARG C7077
GLY C7054
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
LEU C6924
ILE C6925
PHE C6868
ARG C6864
1.63A
None
None
None
FMT  C7106 ( 2.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 8
SER C6872
HIS D4333
CYH D4330
ARG D4331
1.45A18.29
SFG  C7103 ( 4.5A)
None
ZN  D4401 ( 2.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
LEU A6848
ILE A6926
PHE A6868
GLY A6869
1.65A
None
None
None
SFG  A7103 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE A6925
PHE A6985
ARG A7081
GLY A6963
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE C6925
PHE C6985
ARG C7081
GLY C6963
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE C6926
HIS C6867
PHE C6868
ARG C6884
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6wkq NSP10
NSP16
(SARS-CoV-2)		4 / 8
SER A6872
HIS B4333
CYH B4330
ARG B4331
1.45A18.29
SFG  A7103 ( 4.5A)
None
ZN  B4401 ( 2.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
LEU A  73
ILE A  72
TYR A 325
GLY A 157
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
LEU A 251
ILE A 236
HIS A 250
GLY A 247
1.54A
None
None
U5P  A 401 (-4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
LEU A 255
ILE A 281
ARG A 258
GLY A 287
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
LEU A  73
ILE A  72
PHE A 195
GLY A 157
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
LEU B  73
ILE B  72
PHE B 195
GLY B 157
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
LEU B  73
ILE B  72
TYR B 325
GLY B 157
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
LEU A 228
VAL A 237
ILE A 253
PHE A 222
LEU A 215
1.75A21.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
LEU B 228
VAL B 237
ILE B 253
PHE B 222
LEU B 215
1.77A21.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
LEU B 251
ILE B 236
HIS B 250
GLY B 247
1.56A
None
None
U5P  B 401 (-4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
LEU B 255
ILE B 281
ARG B 258
GLY B 287
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
GLU B  69
SER B 198
GLN B 160
VAL B 173
1.11A19.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
GLU A  69
SER A 198
GLN A 160
VAL A 173
1.07A19.80
EDO  A 408 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
ILE A 136
PHE A 140
TYR A 182
GLY A 149
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
LEU A 250
ILE A 249
HIS A 246
GLY A 109
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
LEU A 167
HIS A 172
PHE A 140
ARG A 131
1.63A
U5G  A 401 (-3.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A7004
ILE A7005
ARG A7030
GLY A6806
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A6924
ILE A6925
PHE A6954
ARG A7081
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A6848
ILE A6926
PHE A6868
GLY A6869
1.66A
None
None
None
SAH  A7101 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A6924
ILE A6925
PHE A6868
ARG A6864
1.60A
None
None
None
SO4  A7106 (-3.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 8
SER A6872
HIS B4333
CYH B4330
ARG B4331
1.48A18.29
SO4  A7109 (-4.5A)
None
ZN  B4401 (-2.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A6838
MET A7045
PHE A7048
GLN A6885
ALA A6881
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6925
PHE A6985
ARG A7081
GLY A6963
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
LEU A7073
ILE A7079
ARG A7077
GLY A7054
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 11
THR C   9
LEU C  14
VAL C  58
MET C  52
LEU D  95
1.70A16.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 11
THR A   9
LEU A  14
VAL A  58
MET A  52
LEU B  95
1.68A16.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
LEU A  87
HIS A 164
PHE A 181
TYR A  54
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
LEU A 250
ILE A 249
HIS A 246
GLY A 109
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
PHE A 140
ARG A 131
GLY A 138
LYS A 137
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
ILE A 106
PHE A 112
TYR A 182
GLY A 149
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
LEU A 167
HIS A 172
PHE A 140
LYS A 137
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
PHE A 140
ARG A 131
GLY A 138
LYS A 137
1.77A15.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
SER A 113
GLN A 127
VAL A 297
ARG A 298
1.64A15.82
DMS  A 403 ( 4.9A)
DMS  A 403 (-3.4A)
None
DMS  A 403 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
LEU A 250
ILE A 249
HIS A 246
GLY A 109
1.65A15.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
LEU A  87
HIS A 164
PHE A 181
TYR A  54
1.78A15.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 8
LEU A 119
TYR A  71
ARG A 109
GLY A 107
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 8
LEU A  99
ILE A  44
TYR A  83
GLY A  29
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6yla LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
ILE L  34
PHE E 515
TYR L  38
GLY E 431
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6yla LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
ILE C  34
PHE A 515
TYR C  38
GLY A 431
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
LEU E 335
PHE E 342
TYR E 365
LYS E 356
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
LEU A 250
ILE A 249
HIS A 246
GLY A 109
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6yor IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
ILE L  34
PHE E 515
TYR L  38
GLY E 431
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6yor IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
ILE C  34
PHE A 515
TYR C  38
GLY A 431
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ILE A 136
PHE A 140
TYR A 182
GLY A 149
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
LEU A 250
ILE A 249
HIS A 246
GLY A 109
1.67A
None
None
PEG  A 405 (-3.2A)
PEG  A 405 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 5
ASN B  40
PHE B 132
ALA B  50
GLY B  47
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
LEU C  12
ILE C 137
SER C 139
PHE C 168
MET C 171
1.68A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLU A 114
SER A 111
VAL D  36
HIS D 119
1.77A13.95
None
EDO  D 202 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLU D 114
SER D 111
VAL A  36
HIS A 119
1.78A13.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 5
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 5
ASN D  40
PHE D 132
ALA D  50
GLY D  47
1.75A
EDO  D 206 (-3.9A)
EDO  D 205 ( 3.6A)
EDO  D 206 (-3.6A)
EDO  D 206 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
LEU C  12
ILE C 137
SER C 139
PHE C 168
MET C 171
1.64A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLU D 114
SER D 111
VAL A  36
HIS A 119
1.79A13.95
None
EDO  A 206 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 5
ASN B  40
PHE B 132
ALA B  50
GLY B  47
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLU A 114
SER A 111
VAL C  36
HIS C 119
1.78A13.95
None
EDO  C 205 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 5
ASN C  40
PHE C 132
ALA C  50
GLY C  47
1.74A
MES  C 201 (-4.2A)
MES  C 201 (-3.6A)
MES  C 201 ( 3.8A)
MES  C 201 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
GLU C 114
SER C 111
VAL A  36
HIS A 119
1.78A13.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
LEU A 250
ILE A 249
HIS A 246
GLY A 109
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
LEU A 167
HIS A 172
PHE A 140
ARG A 131
1.60A
None
PJE  C   5 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 11
THR C   9
LEU C  14
VAL C  58
MET C  52
LEU D  95
1.64A15.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 11
THR C   9
LEU C  14
VAL C  58
MET C  52
LEU D 103
1.75A15.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
LEU A 869
PHE A 429
TYR A 884
GLY A 839
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
PHE A 429
TYR A 884
ARG A 836
GLY A 839
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 8
GLU A 658
SER A 635
HIS A 642
CYH A 646
ARG A 654
1.70A20.48
None
None
ZN  A1002 (-3.3A)
ZN  A1002 (-2.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		7btf NSP12
NSP7
(SARS-CoV-2)		4 / 8
LEU C  35
ILE C  39
HIS C  36
PHE A 440
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
LEU A 351
ILE A 632
ARG A 349
GLY A 678
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
VAL A 880
LEU A 883
PHE A 419
ALA A 840
MET A 855
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
ILE A 106
HIS A 113
PHE A   7
GLY A  25
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
LEU A 167
HIS A 172
PHE A 140
ARG A 131
1.65A
DMS  A 405 ( 4.9A)
DMS  A 402 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
LEU A 250
ILE A 249
HIS A 246
GLY A 109
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
LEU A 308
ILE A 307
PHE A 652
GLY A 352
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
PHE A 429
TYR A 884
ARG A 836
GLY A 839
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
SER A 635
HIS A 642
CYH A 646
ARG A 654
1.55A20.61
None
ZN  A1002 (-3.1A)
ZN  A1002 (-2.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
LEU A 869
PHE A 429
TYR A 884
GLY A 839
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
LEU A 891
ILE A 888
TYR A 884
ARG A 858
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
LEU A 308
ILE A 307
PHE A 652
GLY A 352
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
SER A 635
HIS A 642
CYH A 646
ARG A 654
1.38A20.61
None
ZN  A1002 (-3.2A)
ZN  A1002 (-2.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
ILE A 864
PHE A 881
TYR A 915
LYS A 906
1.74A
None
None
U  T  16 ( 4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
LEU A 351
ILE A 632
ARG A 349
GLY A 678
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
LEU A 891
ILE A 888
TYR A 884
ARG A 858
1.41A
None
None
None
U  P  17 ( 3.2A)