Ligand ID: 84G


Drugbank ID:
DB06696
(Arbekacin)


Indication:
Arbekacin is used for the short term treatment of multi-resistant bacterial infections, such as methicillin-resistant Staphylococcus aureus (MRSA).

Get human targets for 84G in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND '84G' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGG_D_84GD600_0
(BIFUNCTIONAL AAC/APH)		6m71 NSP12
(SARS-CoV-2)		5 / 11
ASP A 833
SER A 835
HIS A 439
GLU A 436
GLU A 876
1.51A14.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGG_B_84GB600_0
(BIFUNCTIONAL AAC/APH)		6m71 NSP12
(SARS-CoV-2)		5 / 10
ASP A 833
SER A 835
HIS A 439
GLU A 436
GLU A 876
1.49A14.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGG_D_84GD600_0
(BIFUNCTIONAL AAC/APH)		7btf NSP12
(SARS-CoV-2)		5 / 11
ASP A 833
SER A 835
HIS A 439
GLU A 436
GLU A 876
1.53A14.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGG_D_84GD600_0
(BIFUNCTIONAL AAC/APH)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
ASP A 833
SER A 835
HIS A 439
GLU A 436
GLU A 876
1.54A14.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGG_B_84GB600_0
(BIFUNCTIONAL AAC/APH)		7bv2 NSP12
(SARS-CoV-2)		5 / 10
ASP A 833
SER A 835
HIS A 439
GLU A 436
GLU A 876
1.30A14.09
None