Ligand ID: WPP


Drugbank ID:
DB00319
(Piperacillin)


Indication:
For the treatment of polymicrobial infections.

Get human targets for WPP in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'WPP' AND SARS-RELATED PROTEINS ONLY

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
THR A  26
ASN A  28
SER A 147
GLY A 146
1.38A20.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		5 / 12
GLY B 120
ASN B 142
THR B  25
SER B 147
GLY B 146
1.52A20.81
None
AZP  B 307 (-4.0A)
AZP  B 307 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 12
GLY D 315
ASN B 281
ASN D 281
ASN D 283
GLY D 312
1.38A22.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		2ajf ACE2
(Homo
sapiens)		5 / 12
GLY A 173
ASN A 508
SER A 502
THR A 122
GLY A 130
1.53A18.14
None
None
CL  A 902 ( 4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		2ajf ACE2
SPIKE PROTEIN
(Homo
sapiens;
SARSr-CoV)		5 / 12
GLY E 391
ASN E 424
THR E 485
GLY E 488
ASP A 355
1.48A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		2amd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
THR A  26
ASN A  28
SER A 147
GLY A 146
1.53A21.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		4 / 5
TYR H  43
PRO H  89
THR H  85
THR G  73
1.68A15.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		4 / 5
TYR A  43
PRO A  89
THR A  85
THR B  73
1.77A16.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		4 / 5
TYR E  43
PRO E  89
THR E  85
THR F  73
1.72A16.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
GLY C  48
ASN C 100
ASN B 100
GLY C  47
GLY B 104
1.55A22.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		2gri NSP3
(SARSr)		4 / 5
CYH A 105
PRO A 109
THR A  87
THR A  25
1.10A16.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		2jw8 NUCLEOCAPSID PROTEIN
(SARSr-CoV)		5 / 12
GLY A 279
THR A 363
GLY A 285
GLY A 288
ASP A 289
1.32A18.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		3aw1 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY A 120
ASN A 142
THR A  25
SER A 147
GLY A 146
1.52A20.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		3d0g ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		6 / 12
GLY E 391
ASN E 424
THR E 485
GLY E 490
GLY E 488
ASP A 355
1.72A22.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		3d0h ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
GLY E 391
ASN E 424
THR E 485
GLY E 488
ASP A 355
1.41A22.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		3d0i ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
GLY E 391
ASN E 424
THR E 485
GLY E 488
ASP A 355
1.51A22.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
GLY B 173
ASN B 508
SER B 502
THR B 122
GLY B 130
1.52A18.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY B 170
ASN A 214
GLY B 138
SER B 139
GLY A   2
1.44A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		3sci ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		5 / 12
GLY E 391
ASN E 424
THR E 485
GLY E 488
ASP A 355
1.52A19.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		3scj ACE2
(Homo
sapiens)		5 / 12
GLY B 173
ASN B 508
SER B 502
THR B 122
GLY B 130
1.49A18.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		3scj ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		5 / 12
GLY F 391
THR F 485
GLY F 490
GLY B 354
ASP B 355
1.50A19.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
GLY A 173
ASN A 508
SER A 502
THR A 122
GLY A 130
1.36A18.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		3sck ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
GLY F 391
ASN F 424
THR F 485
GLY F 488
ASP B 355
1.55A21.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		3scl ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
GLY F 391
ASN F 424
THR F 485
GLY F 488
ASP B 355
1.49A21.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		4m0w REPLICASE
POLYPROTEIN 1A
UBIQUITIN
(Bos
taurus;
SARSr-CoV)		5 / 12
GLY B  75
ASN A 110
GLY A 164
GLY A 161
ASP A 109
1.54A14.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		4mds 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY A 120
ASN A 142
THR A  25
SER A 147
GLY A 146
1.54A20.87
None
23H  A 401 (-4.8A)
DMS  A 402 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		4ovz PAPAIN-LIKE
PROTEINASE
(SARS-COV
Urbani)		4 / 5
TYR A 252
PRO A 300
THR A 275
THR A 258
1.79A21.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		5c8s GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		5 / 12
GLY D 102
ASN C   3
THR C   5
GLY C  -1
SER C   0
1.32A16.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		5c8t GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		5 / 12
GLY D 102
ASN C   3
THR C   5
GLY C  -1
SER C   0
1.41A16.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		5e6j REPLICASE
POLYPROTEIN 1AB
UBIQUITIN
(SARSr-CoV;
synthetic
construct)		5 / 12
GLY E  75
ASN D 110
GLY D 164
GLY D 161
ASP D 109
1.49A14.66
AYE  E  76 (-2.4A)
AYE  E  76 ( 4.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 5
CYH C  94
TYR A 465
PRO C 151
THR C  97
1.64A16.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		5tl6 REPLICASE
POLYPROTEIN 1AB
UBIQUITIN-LIKE
PROTEIN ISG15
(Homo
sapiens;
SARSr-CoV)		5 / 12
GLY C 156
ASN D 110
GLY D 164
GLY D 161
ASP D 109
1.51A14.83
AYE  C 157 ( 2.3A)
AYE  C 157 ( 4.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
ASN D  14
THR D  55
GLY D  82
GLY D  39
ASP D  38
1.22A21.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 5
TYR A  88
PRO A  61
THR A 261
THR A 215
1.75A23.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 5
TYR A 886
PRO A 879
THR C 693
THR A 869
1.55A11.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
THR B 533
ASN B 526
SER B 310
GLY B 311
ASP B 312
1.39A11.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 5
TYR B  88
PRO B  61
THR B 260
THR B 215
1.37A11.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER C 362
ASN C 424
THR C 485
GLY C 391
GLY C 490
1.39A11.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 5
TYR A  88
PRO A  61
THR A 261
THR A 215
1.67A11.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
GLY C 580
SER A 717
ASN A 746
ASN C 304
GLY C 579
1.38A11.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 5
TYR B1070
PRO B1061
THR B1059
THR B1098
1.53A11.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
GLY C 580
SER A 717
ASN A 746
ASN C 304
GLY C 579
1.37A11.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		6cs2 ACE2
(Homo
sapiens)		5 / 12
GLY D 173
ASN D 508
SER D 502
THR D 122
GLY D 130
1.46A18.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		6m1d ACE2
(Homo
sapiens)		5 / 12
GLY D 395
ASN D 572
THR D 567
GLY D 561
SER D 563
1.50A15.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
GLY A 391
ASN A 424
THR A 485
GLY A 490
GLY A 488
1.47A11.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
HEAVY CHAIN
(Homo
sapiens)		4 / 5
TYR H 159
PRO H 216
THR H 121
THR H 179
1.76A22.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		6nur NSP12
(SARSr-CoV)		5 / 12
GLY A 683
ASN A 568
SER A 681
GLY A 559
SER A 561
1.54A14.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		6nur NSP12
NSP8
(SARSr-CoV)		4 / 5
TYR B 138
PRO B 133
THR A 393
THR B 187
1.71A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 5
TYR H  32
PRO H  52
THR H  57
THR H 100
1.59A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
ASN L  22
THR L  69
GLY L  64
SER L  65
GLY L  66
1.39A19.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
ASN L  22
THR L  69
GLY L  64
SER L  65
GLY L  66
1.48A19.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 5
TYR H  32
PRO H  52
THR H  57
THR H 100
1.57A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 12
GLY H  28
ASN H  76
GLY H  26
SER H  25
GLY H  24
1.53A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
ASN C  22
THR C  75
GLY C  70
SER C  71
GLY C  72
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
ASN L  22
THR L  75
GLY L  70
SER L  71
GLY L  72
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 5
TYR H  32
PRO H  53
THR H  58
THR H 104
1.48A22.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 5
TYR B  32
PRO B  53
THR B  58
THR B 104
1.58A22.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
ASN C  22
THR C  75
GLY C  70
SER C  71
GLY C  72
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 5
TYR B  32
PRO B  53
THR B  58
THR B 104
1.60A22.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
GLY L  70
SER L  69
SER L  71
GLY L  72
ASP L  76
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
ASN L  22
THR L  75
GLY L  70
SER L  71
GLY L  72
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 5
TYR H  32
PRO H  53
THR H  58
THR H 104
1.45A22.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 5
TYR H  32
PRO H  53
THR H  58
THR H 104
1.46A22.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 5
TYR H  32
PRO H  53
THR H  58
THR H 104
1.49A22.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		6ym0 HEAVY CHAIN
(Homo
sapiens)		5 / 12
GLY H  28
ASN H  77
GLY H  26
SER H  25
GLY H  24
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		5 / 12
SER L  32
ASN L  35
ASN L  37
SER L  28
GLY L  74
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		5 / 12
ASN L  22
THR L  75
GLY L  70
SER L  71
GLY L  72
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		5 / 12
GLY L  70
SER L  69
SER L  71
GLY L  72
ASP L  76
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		5 / 12
ASN L  22
THR L  75
GLY L  70
SER L  71
GLY L  72
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		5 / 12
SER L  32
ASN L  35
ASN L  37
SER L  28
GLY L  74
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
ASN C  22
THR C  75
GLY C  70
SER C  71
GLY C  72
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
ASN L  22
THR L  75
GLY L  70
SER L  71
GLY L  72
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 5
TYR B  32
PRO B  53
THR B  58
THR B 104
1.49A22.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
ASN L  22
THR L  75
GLY L  70
SER L  71
GLY L  72
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 5
TYR H  32
PRO H  53
THR H  58
THR H 104
1.45A22.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 5
TYR B  32
PRO B  53
THR B  58
THR B 104
1.46A22.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
GLY L  70
SER L  69
SER L  71
GLY L  72
ASP L  76
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
ASN C  22
THR C  75
GLY C  70
SER C  71
GLY C  72
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
GLY C  70
SER C  69
SER C  71
GLY C  72
ASP C  76
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 5
TYR H  32
PRO H  53
THR H  58
THR H 104
1.48A22.91
None