Ligand ID: SAN


Drugbank ID:
DB00259
(Sulfanilamide)


Indication:
For the treatment of vulvovaginitis caused by Candida albicans.

Get human targets for SAN in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'SAN' AND SARS-RELATED PROTEINS ONLY

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.66A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		1uk4 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.45A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLU B1166
ASN A 214
GLY A   2
SER A   1
1.35A11.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.58A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		2alv REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.70A21.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		2amq 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
ASN B 214
GLN B 299
GLY B   2
SER A 139
1.45A11.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		2amq 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
HIS A 246
GLU A 240
TYR A 239
ASN A 203
GLY A 109
1.34A11.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		4 / 8
HIS A 335
ASN B 286
GLN B 284
GLY B 285
1.37A5.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.54A20.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		2duc REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 9
HIS A 246
GLU A 240
TYR A 239
ASN A 203
GLY A 109
1.33A11.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 10
GLN C  31
HIS C  51
VAL C  22
VAL C   8
THR C  35
1.65A19.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		2ga6 ORF1A POLYPROTEIN
(SARSr-CoV)		4 / 8
GLU T  60
ASN T  62
GLN T  98
GLY T  52
1.51A6.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		2gib NUCLEOCAPSID PROTEIN
(SARSr-CoV)		4 / 8
HIS B 335
ASN A 286
GLN A 284
GLY A 285
1.30A4.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		5 / 9
HIS B 246
GLU B 240
TYR B 239
ASN B 203
GLY B 109
1.37A11.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		4 / 8
GLU B 290
GLU B 166
GLY A   2
SER A   1
1.51A11.57
None
WR1  B 602 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.67A22.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.67A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 9
HIS B 246
GLU B 240
TYR B 239
ASN B 203
GLY B 109
1.49A11.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.52A20.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		2q6g POLYPEPTIDE CHAIN
REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		4 / 8
GLU B 166
ASN B 142
GLY D   8
SER D   7
1.48A11.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 9
HIS B 246
GLU B 240
TYR B 239
ASN B 203
GLY B 109
1.43A11.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.44A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.64A21.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 9
HIS A 246
GLU A 240
TYR A 239
ASN A 203
GLY A 109
1.37A11.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
GLU A 240
ASN A 203
GLY A 109
1.44A11.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		3avz 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.58A22.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		3aw1 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
HIS B 246
GLU B 240
TYR B 239
ASN B 203
GLY B 109
1.38A11.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		3bgf F26G19 FAB
(Mus
musculus)		5 / 10
VAL B 121
VAL B 144
LEU B 154
THR B 153
THR B 155
1.63A23.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		3bgf F26G19 FAB
(Mus
musculus)		5 / 9
VAL B 121
VAL B 144
LEU B 154
THR B 153
THR B 155
1.62A23.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 8
GLU B 398
GLN B 221
GLY B 220
SER B 218
1.45A15.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		3d62 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
HIS A 246
GLU A 240
TYR A 239
ASN A 203
GLY A 109
1.49A11.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		3e91 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.55A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
HIS A 246
GLU A 240
TYR A 239
ASN A 203
GLY A 109
1.38A11.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLU B 290
GLU B 166
GLY A   2
SER A   1
1.45A11.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		3eaj 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.69A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		3ebn REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.61A18.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.63A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.69A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
HIS B 246
GLU B 240
TYR B 239
ASN B 203
GLY B 109
1.60A11.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.67A22.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
HIS A 246
GLU A 240
TYR A 239
ASN A 203
GLY A 109
1.44A11.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.71A22.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
HIS A 246
GLU A 240
TYR A 239
ASN A 203
GLY A 109
1.43A11.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		3iwm 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLU C 290
GLU A 166
GLY B   2
SER B   1
1.25A11.67
None
PJE  H   5 (-3.4A)
None
PJE  H   5 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLU B 290
GLU B 166
GLY A   2
SER A   1
1.47A11.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
VAL B 261
THR B 225
THR B 226
1.59A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
HIS A 246
GLU A 240
TYR A 239
ASN A 203
GLY A 109
1.36A11.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.68A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 10
GLN A  31
HIS A  51
VAL A  22
VAL A   8
THR A  35
1.56A21.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 8
GLU B 398
GLN B 221
GLY B 220
SER B 218
1.31A15.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		3sna 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
HIS A 246
GLU A 240
TYR A 239
ASN A 203
GLY A 109
1.56A11.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
HIS A 246
GLU A 240
TYR A 239
ASN A 203
GLY A 109
1.43A11.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.67A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLU A 290
GLU A 166
GLY B   2
SER B   1
1.39A11.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		4m0w REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 10
GLN A  31
HIS A  51
VAL A  22
VAL A   8
THR A  35
1.64A23.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		4tww 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLU B 290
GLU B 166
GLY A   2
SER A   1
1.35A11.67
None
3A7  B 401 (-4.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.63A23.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLU B 290
GLU B 166
GLY A   2
SER A   1
1.43A11.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
HIS B 246
GLU B 240
TYR B 239
ASN B 203
GLY B 109
1.36A11.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		5c8u NSP10
(SARSr-CoV)		4 / 8
GLU A  60
ASN A  62
GLN A  98
GLY A  52
1.35A6.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 8
GLU P  60
ASN P  62
GLN P  98
GLY P  52
1.37A5.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 8
HIS A 229
GLN C 168
GLY C 232
SER C 230
1.38A14.94
 ZN  A 601 (-2.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 9
GLU D 264
HIS D 276
TYR D 274
GLY D 288
SER D 115
1.79A10.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 10
GLN B  31
HIS B  51
VAL B  22
VAL B   8
THR B  35
1.64A21.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
TRP D  94
HIS D  90
GLY D  39
SER D  86
1.49A10.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 8
GLU C1074
GLU A1074
ASN A 889
GLY A 892
1.39A21.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 8
GLU C1074
ASN C1090
GLN C1088
GLY C 892
1.48A21.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		6jyt HELICASE
(SARSr-CoV)		4 / 8
GLU A 418
HIS A 554
ASN A 557
SER A 555
1.49A15.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		6m18 ACE2
(Homo
sapiens)		4 / 8
GLU D 145
GLU D 171
GLN D 175
GLY D 173
1.29A18.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 8
HIS C 524
GLU C 519
ASN C 527
GLN C 531
1.45A17.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F92_B_SANB2201_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		6m1d ACE2
(Homo
sapiens)		5 / 9
GLU D 208
TYR D 207
GLN D 221
GLY D 220
SER D 218
1.57A18.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
GLU A1074
ASN A1090
GLN A1088
GLY A 892
1.24A22.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		6nur NSP12
(SARSr-CoV)		4 / 8
ASN A 215
GLN A 210
GLY A 214
SER A 185
1.39A19.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
GLU L  81
GLU L  55
GLY L  57
SER L  56
1.55A6.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 8
ASN H  77
GLN C  48
GLY H  24
SER H  25
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 8
GLU L  87
GLU L  61
GLY L  63
SER L  62
1.72A
None
None
None
MLI  B 303 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 8
GLU C  87
GLU C  61
GLY C  63
SER C  62
1.73A
None
None
None
MLI  B 303 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 8
ASN B  77
GLN L  48
GLY B  24
SER B  25
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 8
GLU L  87
GLU L  61
GLY L  63
SER L  62
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 8
GLU L  87
GLU L  61
GLY L  63
SER L  62
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 8
GLU C  87
GLU C  61
GLY C  63
SER C  62
1.72A
None