Ligand ID: 803


Drugbank ID:
DB00227
(Lovastatin)


Indication:
For management as an adjunct to diet to reduce elevated total-C, LDL-C, apo B, and TG levels in patients with primary hypercholesterolemia and mixed dyslipidemia. For primary prevention of coronary heart disease and to slow progression of coronary atherosclerosis in patients with coronary heart disease.

Get human targets for 803 in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND '803' AND SARS-RELATED PROTEINS ONLY

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		1zvb E2 GLYCOPROTEIN
(SARSr-CoV)		4 / 7
VAL B   6
LEU C   9
VAL C   6
LEU A   5
1.22A8.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		1zvb E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 10
LEU C  24
ILE B  23
GLU B  31
LEU A  27
VAL C  30
1.45A8.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 10
LEU A 194
VAL A 198
ILE A 200
LEU A 342
LEU A 319
1.04A22.28
None
None
None
GOL  A1010 (-4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		4 / 7
LEU A 194
VAL A 198
LEU A 342
LEU A 319
1.16A22.28
None
None
GOL  A1010 (-4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		2ahm REPLICASE
POLYPROTEIN 1AB,
LIGHT CHAIN
(SARSr-CoV)		4 / 7
VAL C  71
LEU C  22
VAL C  27
LEU C  65
1.06A21.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
LEU C 920
VAL E1171
LEU D1179
LEU D1175
1.02A12.09
None
None
ACE  B 913 ( 4.8A)
ACE  B 913 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		5 / 10
LEU E  22
VAL E  93
ILE E  45
LEU E  53
VAL F  77
1.48A15.47
D10  F1099 ( 4.8A)
None
D10  F1099 ( 4.5A)
None
D10  F1099 (-4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		5 / 10
LEU H  22
VAL H  93
ILE H  45
LEU H  53
VAL G  77
1.46A22.69
None
None
D10  H1099 ( 4.5A)
D10  H1099 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		4 / 7
VAL A  93
LEU B  22
LEU B  53
LEU B  55
1.21A16.02
None
None
D10  B1099 (-4.4A)
D10  B1099 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		4 / 7
VAL C  93
LEU D  22
LEU D  53
LEU D  55
1.18A22.69
None
None
D10  C1099 ( 4.8A)
D10  C1099 ( 4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		4 / 7
VAL E  93
LEU F  22
LEU F  53
LEU F  55
1.17A15.47
None
None
D10  F1099 ( 4.7A)
D10  F1099 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		5 / 10
LEU A  22
VAL A  93
ILE A  45
LEU A  53
VAL B  77
1.48A16.02
None
None
None
D10  B1099 ( 4.6A)
D10  B1099 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		4 / 7
VAL B  93
LEU A  22
LEU A  53
LEU A  55
1.18A16.57
None
None
D10  B1099 ( 4.6A)
D10  B1099 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		5 / 10
LEU B  22
VAL B  93
ILE B  45
LEU B  53
VAL A  77
1.46A16.57
None
None
None
D10  B1099 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		2dd8 IGG HEAVY CHAIN
IGG LIGHT CHAIN
(Homo
sapiens)		4 / 7
VAL H 181
LEU H 141
VAL H 142
LEU L 136
1.03A18.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 10
LEU B  13
VAL B  17
ILE B  19
LEU B 161
LEU B 138
1.04A22.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		4 / 7
LEU B  13
VAL B  17
LEU B 161
LEU B 138
1.15A22.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		5 / 10
LEU A 248
ILE A 280
TYR A 278
GLU A 201
LEU A 200
1.26A20.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		2hsx LEADER PROTEIN
P65 HOMOLOG
NSP1
(SARSr-CoV)		5 / 10
LEU A  42
VAL A  95
ILE A  60
LEU A 112
LEU A  35
1.58A21.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 10
LEU A 122
VAL A 141
ILE A 143
TYR A 178
LYS A  70
1.46A20.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		2qc2 3C-LIKE PROTEINASE
(-)		4 / 7
LEU A  89
VAL A  77
LEU A  57
LEU A  58
1.20A19.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 10
VAL C 320
ILE C 322
TYR C 193
GLU C 210
LEU C 250
1.17A20.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		2wct NSP3
(SARSr-CoV)		4 / 7
VAL A 589
TYR A 583
LEU A 546
LEU A 603
1.20A21.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 7
VAL A 288
LEU A 111
VAL A 118
LEU A  94
1.23A18.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		2xyr PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 10
LEU A 262
ILE A 267
LEU A 212
GLU A 276
LEU A 275
1.59A17.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		4 / 7
LEU B 217
VAL B 221
LYS B 196
LEU B 200
1.18A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 7
VAL A 288
LEU A 111
VAL A 118
LEU A  94
1.26A18.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 7
VAL D 316
VAL D 381
TYR D 511
LEU D 442
1.17A16.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 10
VAL D 381
ILE D 397
TYR D 511
LYS D 440
LEU D 442
1.55A16.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 7
VAL B 316
VAL B 381
TYR B 511
LEU B 442
1.19A16.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 10
VAL D 381
ILE D 397
TYR D 511
LYS D 440
LEU D 442
1.51A16.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		5f22 NSP7
(SARSr-CoV)		5 / 10
LEU A  76
ILE A  73
LEU A  65
LEU A  64
VAL A  21
1.47A21.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 7
VAL C 316
VAL C 381
TYR C 511
LEU C 442
1.12A15.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 10
VAL A 381
ILE A 397
TYR A 511
LYS A 440
LEU A 442
1.59A15.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		5tl6 UBIQUITIN-LIKE
PROTEIN ISG15
(Homo
sapiens)		5 / 7
VAL C 148
LEU C 137
VAL C  98
TYR C  96
LEU C 124
1.68A20.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 7
LEU D 217
VAL D 221
LYS D 196
LEU D 200
1.19A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		5tl7 UBIQUITIN-LIKE
PROTEIN ISG15
(Mus
musculus)		5 / 7
VAL C 146
LEU C 135
VAL C  96
TYR C  94
LEU C 122
1.60A17.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		5tl7 UBIQUITIN-LIKE
PROTEIN ISG15
(Mus
musculus)		5 / 10
LEU A 135
VAL A  96
LEU A 122
LYS A 148
VAL A 146
1.49A17.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		5x29 ENVELOPE SMALL
MEMBRANE PROTEIN
(SARSr-CoV)		4 / 7
VAL C  25
LEU C  19
LEU A  19
LEU B  19
1.06A18.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		5x5f S PROTEIN
(MERS-CoV)		4 / 7
VAL B 360
VAL B 659
LEU B 759
LEU B 735
1.23A9.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		5x5f S PROTEIN
(MERS-CoV)		5 / 10
LEU B 441
VAL B 575
ILE B 573
LEU B 415
LEU B 411
1.41A9.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
LEU A1045
ILE A 916
LEU A 803
LEU A 804
VAL A 708
1.53A9.39
LEU  A1045 ( 0.6A)
ILE  A 916 ( 0.7A)
LEU  A 803 ( 0.6A)
LEU  A 804 ( 0.5A)
VAL  A 708 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		5y3e REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		4 / 7
LEU A 217
VAL A 221
LYS A 196
LEU A 200
1.25A18.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		5zvm SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
VAL C 958
LEU A 959
VAL A 958
LEU B 966
1.22A19.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		5zvm SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
LEU A 959
VAL A 958
ILE A 962
LEU B 966
VAL C 958
1.33A19.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
VAL C 196
VAL C 123
LEU C 224
LEU C 222
1.13A9.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		6ack ACE2
(Homo
sapiens)		5 / 10
LEU D 554
VAL D 404
ILE D 407
LEU D 539
VAL D 574
1.61A15.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
LEU B 224
ILE B 125
TYR B 163
LYS B 198
VAL B 196
1.40A9.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 7
VAL A 990
LEU A 941
TYR A 723
LEU A 749
1.23A9.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		6crz SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 10
LEU C 224
ILE C 125
TYR C 163
LYS C 198
VAL C 196
1.32A9.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 10
VAL A 103
ILE A 287
LEU A  85
LEU A  88
VAL A 505
1.54A16.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		6m1d ACE2
(Homo
sapiens)		4 / 7
LEU B 262
VAL B 487
LEU B 444
LEU B 278
1.21A13.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 7
VAL A 448
LYS A 112
LEU A 101
LEU A 446
1.24A16.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
LEU C 983
ILE C 724
TYR C 723
LEU C 959
LEU C 978
1.56A10.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		6nur NSP12
NSP8
(SARSr-CoV)		4 / 7
VAL A 335
LEU B  95
LEU A 371
LEU A 366
1.22A12.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		6vw1 ACE2
(Homo
sapiens)		4 / 7
VAL A 404
LEU A 529
LEU A 560
LEU A 558
1.23A15.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
VAL H  67
LEU H  18
VAL H 109
TYR H  90
1.65A20.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 7
LEU L  11
VAL L  13
LEU L  47
LEU L  73
1.43A23.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 10
LEU H  18
VAL H 109
ILE H  20
TYR H  90
VAL H  67
1.72A20.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 10
ILE H  20
TYR H  90
LEU H  82
LYS H  83
VAL H 111
1.35A20.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
VAL H 169
LEU H 141
VAL H 142
TYR H 145
1.57A20.11
GOL  L 301 (-4.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 10
ILE B  20
TYR B  94
LEU B  86
LYS B  87
VAL B 117
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 10
ILE H  20
TYR H  94
LEU H  86
LYS H  87
VAL H 117
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 10
LEU H  18
VAL H 115
ILE H  20
TYR H  94
VAL H  68
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 10
LEU B  18
VAL B 115
ILE B  20
TYR B  94
VAL B  68
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		6ym0 HEAVY CHAIN
(Homo
sapiens)		5 / 10
LEU H  18
VAL H 115
ILE H  20
TYR H  94
VAL H  68
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		6ym0 HEAVY CHAIN
(Homo
sapiens)		5 / 10
ILE H  20
TYR H  94
LEU H  86
LYS H  87
VAL H 117
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		6yor IGG H CHAIN
(Homo
sapiens)		5 / 10
LEU B  18
VAL B 115
ILE B  20
TYR B  94
VAL B  68
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		6yor IGG H CHAIN
(Homo
sapiens)		5 / 10
ILE H  20
TYR H  94
LEU H  86
LYS H  87
VAL H 117
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		6yor IGG H CHAIN
(Homo
sapiens)		5 / 10
LEU H  18
VAL H 115
ILE H  20
TYR H  94
VAL H  68
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		6yor IGG H CHAIN
(Homo
sapiens)		5 / 10
ILE B  20
TYR B  94
LEU B  86
LYS B  87
VAL B 117
1.26A
None