Ligand ID: AIN


Drugbank ID:
DB00945
(Acetylsalicylic acid)


Indication:
For use in the temporary relief of various forms of pain, inflammation associated with various conditions (including rheumatoid arthritis, juvenile rheumatoid arthritis, systemic lupus erythematosus, osteoarthritis, and ankylosing spondylitis), and is also used to reduce the risk of death and/or nonfatal myocardial infarction in patients with a previous infarction or unstable angina pectoris.

Get human targets for AIN in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'AIN'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		3 / 3
LEU B   0
ALA B 210
ILE B 213
0.75A17.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		1qz8 POLYPROTEIN 1AB
(SARSr-CoV)		4 / 4
LEU B  69
GLY B  17
ASP B  50
TYR B  89
1.33A20.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		1uw7 NSP9
(SARS-COV
HKU-39849)		4 / 4
LEU A  69
GLY A  17
ASP A  50
TYR A  89
1.27A16.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		1wof 3C-LIKE PROTEINASE
(SARSr-CoV)		3 / 3
LEU A  -2
ALA A 210
ILE A 213
0.82A16.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		1ysy REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		3 / 3
LEU A  61
ALA A  67
ILE A  70
0.93A17.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
REPLICASE
POLYPROTEIN 1AB,
LIGHT CHAIN
(SARSr-CoV)		3 / 3
LEU C  64
ALA G 115
ILE G 112
0.67A16.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
(SARSr-CoV)		3 / 3
LEU H 158
ALA H 193
ILE H 161
1.03A17.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		4 / 6
ARG C 294
PHE C 364
GLN B 295
PRO C 365
1.76A13.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		2dd8 IGG LIGHT CHAIN
(Homo
sapiens)		3 / 3
GLU L   4
GLY L  99
THR L 100
1.00A21.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		3 / 3
GLU A 180
GLY A 202
THR A 201
0.74A21.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		2g9t ORF1A POLYPROTEIN
(SARSr-CoV)		4 / 6
HIS R  48
GLU L  66
PHE L  68
PRO L 107
1.09A13.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		2g9t ORF1A POLYPROTEIN
(SARSr-CoV)		4 / 6
HIS R  48
GLU L  66
PHE L  68
PRO L 107
1.06A13.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		3 / 3
LEU A 122
ALA A  94
ILE A  69
1.03A15.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		2jzd REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		3 / 3
GLU A 618
GLY A 646
THR A 643
1.04A18.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		2jzf REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		3 / 3
GLU A 618
GLY A 646
THR A 643
0.92A18.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		2k7x REPLICASE
POLYPROTEIN 1AB MAIN
PROTEASE
(SARS-COV
Sino1-11)		3 / 3
LEU A 220
ALA A 211
ILE A 281
1.00A19.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		2k87 NSP3 OF REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		3 / 3
LEU A  58
ALA A  64
ILE A  85
0.98A22.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		2kqv NSP3
(SARSr-CoV)		3 / 3
GLU A  96
GLY A 124
THR A 121
0.91A21.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		2mm4 ENVELOPE SMALL
MEMBRANE PROTEIN
(SARSr)		3 / 3
GLU A   8
GLY A  10
THR A   9
0.77A10.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		2ofz NUCLEOCAPSID PROTEIN
(SARS-COV
Tor2)		3 / 3
LEU A 114
ALA A 139
ILE A  -3
0.67A18.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 6
HIS B 242
GLU D 326
GLN D 188
PRO D 190
1.46A19.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 6
HIS B 242
GLU D 326
GLN D 188
PRO D 190
1.52A19.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		3 / 3
LEU D 122
ALA D  94
ILE D  69
0.88A15.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		2w2g NSP3
(SARSr)		3 / 3
GLU A 524
GLY A 527
THR A 528
0.90A20.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		3 / 3
LEU A 144
ALA A 164
ILE A 151
1.01A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		3e9s NSP3
(SARSr-CoV)		3 / 3
GLU A 180
GLY A 202
THR A 201
0.64A21.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		3ea9 3C-LIKE PROTEINASE
(SARSr-CoV)		3 / 3
LEU A 220
ALA A 211
ILE A 281
1.05A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		3ee7 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		4 / 4
LEU A  69
GLY A  17
ASP A  50
TYR A  89
1.26A19.71
None
None
GOL  A 126 (-3.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		3i6g BETA-2-MICROGLOBULIN
(Homo
sapiens)		4 / 6
ARG B  12
GLU B  69
PHE B  70
PRO B  72
1.75A10.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		3i6l HLA, A-24
(Homo
sapiens)		3 / 3
GLU D  62
GLY D  65
THR D  64
0.72A20.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		3iwm 3C-LIKE PROTEINASE
(SARSr-CoV)		3 / 3
LEU C 220
ALA C 211
ILE A 281
1.01A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		4m0w REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		3 / 3
GLU A 180
GLY A 202
THR A 201
0.93A22.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		4mm3 PAPAIN-LIKE
PROTEINASE
(SARSr-CoV)		3 / 3
GLU B 180
GLY B 202
THR B 201
0.84A21.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		3 / 3
LEU A 220
ALA A 211
ILE A 281
1.00A17.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		3 / 3
GLU B 132
GLY B 123
THR B 122
1.07A20.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NSB_A_AINA402_1
(CHITINASE-3-LIKE
PROTEIN 1)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 7
THR B 113
ARG B  84
TRP B  86
LEU B 174
1.67A19.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		3 / 3
GLU D 180
GLY D 202
THR D 201
0.56A22.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		5e6j POLYUBIQUITIN-B
REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV;
synthetic
construct)		4 / 4
LEU F  50
GLY F  47
ASP D  63
TYR F  59
1.71A20.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
LEU A 205
ALA A 260
ILE A 259
1.61A22.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
LEU A 220
ALA A 211
ILE A 281
1.20A22.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
GLU A 288
GLY A 283
THR A 280
1.57A17.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
GLU A 178
GLY A 179
THR A 175
1.59A17.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		3 / 3
GLU D 180
GLY D 202
THR D 201
0.66A21.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		5x29 ENVELOPE SMALL
MEMBRANE PROTEIN
(SARSr-CoV)		3 / 3
GLU B   8
GLY B  10
THR B  11
1.08A12.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
GLU A 268
GLY A 270
THR A 271
1.07A22.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		3 / 3
LEU A 597
ALA A 639
ILE A 674
0.73A6.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 4
LEU C 286
GLY C 587
ASP C 296
TYR C 300
1.38A7.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		5x5f S PROTEIN
(MERS-CoV)		3 / 3
LEU C1058
ALA B 432
ILE C1055
0.76A6.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		5x5f S PROTEIN
(MERS-CoV)		4 / 4
LEU A 638
GLY A 578
ASP A 580
TYR A 632
1.43A7.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
GLU C 268
GLY C 270
THR C 271
0.53A14.29
GLU  C 268 ( 0.5A)
GLY  C 270 ( 0.0A)
THR  C 271 ( 0.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 4
LEU B 286
GLY B 587
ASP B 296
TYR B 300
1.29A7.06
LEU  B 286 ( 0.6A)
GLY  B 587 ( 0.0A)
ASP  B 296 ( 0.5A)
TYR  B 300 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		5y3q REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		3 / 3
GLU A 180
GLY A 202
THR A 201
0.62A21.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
LEU B1045
ALA B 912
ILE B 913
0.75A6.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 4
LEU A 286
GLY A 587
ASP A 296
TYR A 300
1.25A7.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
GLU A 268
GLY A 270
THR A 271
1.00A14.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		3 / 3
LEU A 194
ALA A 127
ILE A 226
0.93A7.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		3 / 3
GLU C 268
GLY C 270
THR C 271
1.00A14.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 4
LEU B 286
GLY B 587
ASP B 296
TYR B 300
1.24A6.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		3 / 3
LEU C 355
ALA C 350
ILE C 345
0.81A6.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		3 / 3
GLU B 268
GLY B 270
THR B 271
0.87A14.55
NAG  B1303 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 4
LEU B 286
GLY B 587
ASP B 296
TYR B 300
1.30A7.08
None
None
NAG  B1308 (-4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ARG C 306
PHE A 837
GLN A 835
PRO C 575
1.64A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ARG C 306
PHE A 837
GLN A 835
PRO C 575
1.62A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		3 / 3
GLU A 288
GLY A 283
THR A 280
1.57A23.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6lze VIRAL PROTEASE
(SARS-CoV-2)		3 / 3
LEU A 220
ALA A 211
ILE A 281
1.20A17.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6lzg ACE2
(Homo
sapiens)		3 / 3
LEU A 144
ALA A 164
ILE A 151
1.02A11.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6m0j ACE2
(Homo
sapiens)		3 / 3
LEU A 144
ALA A 164
ILE A 151
1.04A11.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		6m0j ACE2
(Homo
sapiens)		4 / 6
HIS A 540
GLU A 430
PHE A 428
GLN A 429
1.56A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		6m0j ACE2
(Homo
sapiens)		4 / 6
HIS A 540
GLU A 430
PHE A 428
GLN A 429
1.61A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		3 / 3
GLU A 288
GLY A 283
THR A 280
1.56A23.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		3 / 3
LEU A 220
ALA A 211
ILE A 281
1.20A17.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		3 / 3
LEU C 429
ALA C 222
ILE C 225
0.90A10.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		3 / 3
GLU A 217
GLY A 220
THR A 219
0.62A19.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6m1d ACE2
(Homo
sapiens)		3 / 3
LEU B 529
ALA B 533
ILE B 544
0.89A9.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
GLU C 178
GLY C 179
THR C 175
1.63A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
GLU D 178
GLY D 179
THR D 175
1.62A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
GLU A 178
GLY A 179
THR A 175
1.59A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
GLU A 288
GLY A 283
THR A 280
1.57A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
GLU B 178
GLY B 179
THR B 175
1.65A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
GLU B 288
GLY B 283
THR B 280
1.54A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6m2q 3CL PROTEASE
(SARS-CoV-2)		3 / 3
LEU A 220
ALA A 211
ILE A 281
1.20A16.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		3 / 3
GLU A 288
GLY A 283
THR A 280
1.57A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6m3m NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
GLU B 137
GLY C 165
THR C 166
0.97A17.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6m71 NSP7
NSP8
(SARS-CoV-2)		3 / 3
LEU C  59
ALA D 110
ILE C  68
1.15A19.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6m71 NSP7
NSP8
(SARS-CoV-2)		3 / 3
LEU C  59
ALA D 110
ILE D 107
0.85A19.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6m71 NSP12
(SARS-CoV-2)		3 / 3
LEU A 883
ALA A 866
ILE A 837
1.12A8.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6m71 NSP7
NSP8
(SARS-CoV-2)		3 / 3
LEU C  56
ALA D 110
ILE C  68
1.17A19.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6m71 NSP12
(SARS-CoV-2)		3 / 3
LEU A 749
ALA A 699
ILE A 696
1.25A8.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6m71 NSP12
(SARS-CoV-2)		3 / 3
LEU A 758
ALA A 580
ILE A 579
1.36A8.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6m71 NSP12
(SARS-CoV-2)		3 / 3
LEU A 514
ALA A 502
ILE A 562
1.14A8.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6m71 NSP12
(SARS-CoV-2)		3 / 3
LEU A 575
ALA A 580
ILE A 589
1.06A8.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6m71 NSP12
(SARS-CoV-2)		3 / 3
LEU A 437
ALA A 840
ILE A 548
1.14A8.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 4
LEU B 286
GLY B 587
ASP B 296
TYR B 300
1.43A7.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
LIGHT CHAIN
(Homo
sapiens)		4 / 6
ARG L  51
PHE L 103
GLN L  95
PRO L 101
1.57A15.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
LIGHT CHAIN
(Homo
sapiens)		4 / 6
ARG L  51
PHE L 103
GLN L  95
PRO L 101
1.67A15.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6nur NSP8
(SARSr-CoV)		3 / 3
LEU D 103
ALA D 150
ILE D 120
1.04A16.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6nur NSP7
NSP8
(SARSr-CoV)		3 / 3
LEU C  59
ALA D 110
ILE D 107
0.81A17.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6nus NSP12
(SARSr-CoV)		3 / 3
LEU A 883
ALA A 866
ILE A 837
0.84A10.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
GLU A 309
GLY A 311
THR A 599
1.06A14.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
GLU C 281
GLY C 283
THR C 284
0.99A14.00
NAG  C1305 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
GLU C 309
GLY C 601
THR C 602
0.65A14.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6w37 PROTEIN 7A
(SARS-CoV-2)		3 / 3
GLU A  18
GLY A  23
THR A  24
1.72A12.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		3 / 3
LEU C 492
ALA C 352
ILE C 468
1.23A21.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		3 / 3
LEU H  80
ALA H  78
ILE H  51
1.06A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		3 / 3
LEU C 452
ALA C 352
ILE C 468
1.35A21.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		3 / 3
LEU H  80
ALA H  78
ILE H  34
1.28A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		3 / 3
LEU L 179
ALA L 193
ILE L 117
1.56A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		6w4b NSP9
(SARS-CoV-2)		4 / 4
LEU B  70
GLY B  18
ASP B  51
TYR B  90
1.44A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A6924
ALA A6858
ILE A7079
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A6825
ALA A6997
ILE A7035
1.69A21.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A7073
ALA A6960
ILE A7079
1.70A21.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A6959
ALA A6966
ILE A6967
1.55A21.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A7073
ALA A6858
ILE A7079
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
LEU A 220
ALA A 211
ILE A 281
1.16A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
GLU A 288
GLY A 283
THR A 280
1.59A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w6y NSP3
(SARS-CoV-2)		3 / 3
LEU A 126
ALA A 124
ILE A  23
1.57A18.52
AMP  A 201 ( 4.4A)
None
AMP  A 201 ( 4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w6y NSP3
(SARS-CoV-2)		3 / 3
LEU A 126
ALA A 154
ILE A  23
1.43A18.52
AMP  A 201 ( 4.4A)
AMP  A 201 ( 4.5A)
AMP  A 201 ( 4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w6y NSP3
(SARS-CoV-2)		3 / 3
LEU B 126
ALA B 154
ILE B  23
1.47A18.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w6y NSP3
(SARS-CoV-2)		3 / 3
LEU B 126
ALA B 124
ILE B  23
1.60A18.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU A7073
ALA A6858
ILE A7079
1.25A18.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU C7073
ALA C6858
ILE C7079
1.25A18.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU C6924
ALA C6858
ILE C7079
1.27A18.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU C6857
ALA C6966
ILE C7005
1.27A18.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU A7073
ALA A6960
ILE A7079
1.68A18.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU A6924
ALA A6858
ILE A7079
1.27A18.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU A6825
ALA A6997
ILE A7035
1.72A18.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU A6959
ALA A6966
ILE A6967
1.59A18.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU C7073
ALA C6960
ILE C7079
1.69A18.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU C6825
ALA C6997
ILE C7035
1.71A18.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		4 / 4
LEU A  69
GLY A  17
ASP A  50
TYR A  89
1.31A19.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wcf NSP3
(SARS-CoV-2)		3 / 3
LEU A 126
ALA A 154
ILE A  23
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wiq NSP8
(SARS-CoV-2)		3 / 3
LEU B 128
ALA B 150
ILE B 106
1.16A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wiq NSP7
NSP8
(SARS-CoV-2)		3 / 3
LEU A  59
ALA B 110
ILE B 107
0.81A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wiq NSP7
NSP8
(SARS-CoV-2)		3 / 3
LEU A  59
ALA B 110
ILE A  68
0.95A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wiq NSP7
NSP8
(SARS-CoV-2)		3 / 3
LEU A  56
ALA B 110
ILE A  68
1.17A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
GLU C 323
GLY C 328
THR C 329
1.06A13.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
GLU E 323
GLY E 328
THR E 329
1.00A13.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
GLU F 323
GLY F 328
THR F 329
1.04A13.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
LEU B 339
ALA B 336
ILE B 337
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A7073
ALA A6858
ILE A7079
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A6924
ALA A6858
ILE A7079
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU C7073
ALA C6858
ILE C7079
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU C6924
ALA C6858
ILE C7079
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
GLU D 118
GLY D 116
THR D 115
1.28A16.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
GLU B 118
GLY B 116
THR B 115
1.18A16.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
GLU C 118
GLY C 116
THR C 115
1.29A16.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
GLU A 118
GLY A 116
THR A 115
1.28A16.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU A7073
ALA A6858
ILE A7079
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU A6924
ALA A6858
ILE A7079
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU C7073
ALA C6858
ILE C7079
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU C6924
ALA C6858
ILE C7079
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
LEU A 228
ALA A 232
ILE A 236
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
LEU B 228
ALA B 232
ILE B 236
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
GLU A 178
GLY A 179
THR A 175
1.57A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
LEU A 220
ALA A 211
ILE A 281
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A6924
ALA A6858
ILE A7079
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A7073
ALA A6858
ILE A7079
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A6857
ALA A6966
ILE A7005
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wqd NSP7
NSP8
(SARS-CoV-2)		3 / 3
LEU C  59
ALA D 110
ILE D 107
0.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wqd NSP8
(SARS-CoV-2)		3 / 3
LEU B 128
ALA B 150
ILE B 106
1.12A
None
EDO  B 302 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wqd NSP7
NSP8
(SARS-CoV-2)		3 / 3
LEU A  59
ALA B 110
ILE B 107
0.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wqd NSP8
(SARS-CoV-2)		3 / 3
LEU D 128
ALA D 150
ILE D 106
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
LEU A 220
ALA A 211
ILE A 281
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
LEU A 220
ALA A 211
ILE A 281
1.19A22.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
GLU A 178
GLY A 179
THR A 175
1.60A17.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
LEU A 205
ALA A 260
ILE A 259
1.62A22.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		3 / 3
LEU C  59
ALA D 110
ILE D 107
0.81A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		3 / 3
LEU A  59
ALA B 110
ILE B 107
0.85A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		3 / 3
LEU B  95
ALA B 102
ILE B 106
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		3 / 3
LEU B 128
ALA B 150
ILE B 106
1.09A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		3 / 3
LEU D 128
ALA D 150
ILE D 106
1.12A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU E 425
ALA E 419
ILE E 418
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yla HEAVY CHAIN
(Homo
sapiens)		3 / 3
LEU H  81
ALA H  79
ILE H  51
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yla HEAVY CHAIN
(Homo
sapiens)		3 / 3
LEU B  81
ALA B  79
ILE B  34
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yla HEAVY CHAIN
(Homo
sapiens)		3 / 3
LEU B  81
ALA B  79
ILE B  51
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU E 492
ALA E 352
ILE E 468
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU A 492
ALA A 352
ILE A 468
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yla HEAVY CHAIN
(Homo
sapiens)		3 / 3
LEU H  81
ALA H  79
ILE H  34
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6ym0 HEAVY CHAIN
(Homo
sapiens)		3 / 3
LEU H  81
ALA H  79
ILE H  51
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU E 492
ALA E 352
ILE E 468
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6ym0 HEAVY CHAIN
(Homo
sapiens)		3 / 3
LEU H  81
ALA H  79
ILE H  34
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
GLU A 288
GLY A 283
THR A 280
1.59A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
LEU A 220
ALA A 211
ILE A 281
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yor IGG H CHAIN
(Homo
sapiens)		3 / 3
LEU H  81
ALA H  79
ILE H  51
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yor IGG H CHAIN
(Homo
sapiens)		3 / 3
LEU B  81
ALA B  79
ILE B  34
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yor IGG H CHAIN
(Homo
sapiens)		3 / 3
LEU H  81
ALA H  79
ILE H  34
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU A 492
ALA A 352
ILE A 468
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU E 492
ALA E 352
ILE E 468
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU A 425
ALA A 419
ILE A 418
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU E 425
ALA E 419
ILE E 418
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yor IGG H CHAIN
(Homo
sapiens)		3 / 3
LEU B  81
ALA B  79
ILE B  51
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
GLU A 288
GLY A 283
THR A 280
1.60A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
LEU A 220
ALA A 211
ILE A 281
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU D 126
ALA D 154
ILE D  23
1.42A
None
EDO  D 208 (-4.2A)
EDO  D 208 (-4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU A 126
ALA A 154
ILE A  23
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU C 126
ALA C 154
ILE C  23
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU D 126
ALA D 154
ILE D  23
1.40A
APR  D 201 (-4.5A)
APR  D 201 (-4.5A)
APR  D 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU A 126
ALA A 154
ILE A  23
1.41A
APR  A 201 (-4.8A)
APR  A 201 (-4.4A)
APR  A 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU E 126
ALA E 154
ILE E  23
1.42A
APR  E 201 (-4.7A)
APR  E 201 (-4.5A)
APR  E 201 (-4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU B 126
ALA B 154
ILE B  23
1.42A
APR  B 201 (-4.7A)
APR  B 201 (-4.5A)
APR  B 201 (-4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU C 126
ALA C 154
ILE C  23
1.40A
APR  C 201 (-4.8A)
APR  C 201 (-4.5A)
APR  C 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU C 126
ALA C 154
ILE C  23
1.41A
None
EDO  C 206 (-4.4A)
EDO  C 206 (-4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU A 126
ALA A 154
ILE A  23
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		3 / 3
GLU A 288
GLY A 283
THR A 280
1.56A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7bqy MAIN PROTEASE
(SARS-CoV-2)		3 / 3
LEU A 220
ALA A 211
ILE A 281
1.17A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		3 / 3
GLU A 178
GLY A 179
THR A 175
1.62A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7btf NSP12
(SARS-CoV-2)		3 / 3
LEU A 758
ALA A 580
ILE A 579
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7btf NSP7
NSP8
(SARS-CoV-2)		3 / 3
LEU C  59
ALA D 110
ILE D 107
0.83A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7btf NSP12
(SARS-CoV-2)		3 / 3
LEU A 749
ALA A 699
ILE A 696
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7btf NSP12
(SARS-CoV-2)		3 / 3
LEU A 514
ALA A 502
ILE A 562
1.17A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7btf NSP8
(SARS-CoV-2)		3 / 3
LEU D 128
ALA D 150
ILE D 106
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7btf NSP12
(SARS-CoV-2)		3 / 3
LEU A 883
ALA A 866
ILE A 837
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7btf NSP12
(SARS-CoV-2)		3 / 3
LEU A 437
ALA A 840
ILE A 548
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
GLU A 665
GLY A 679
THR A 680
1.34A15.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		3 / 3
LEU A 220
ALA A 211
ILE A 281
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		3 / 3
LEU A 250
ALA A 260
ILE A 259
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		3 / 3
GLU A 288
GLY A 283
THR A 280
1.58A23.63
None
DMS  A 404 ( 4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7bv1 NSP8
(SARS-CoV-2)		3 / 3
LEU D 128
ALA D 150
ILE D 106
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
LEU A 437
ALA A 840
ILE A 548
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
LEU A 758
ALA A 580
ILE A 579
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
LEU A 749
ALA A 699
ILE A 696
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7bv1 NSP7
NSP8
(SARS-CoV-2)		3 / 3
LEU C  59
ALA D 110
ILE D 107
0.93A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
LEU A 883
ALA A 866
ILE A 837
1.04A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7bv1 NSP8
(SARS-CoV-2)		3 / 3
LEU D 153
ALA D 188
ILE D 156
0.86A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7bv1 NSP7
NSP8
(SARS-CoV-2)		3 / 3
LEU C  59
ALA D 110
ILE D 106
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
LEU A 514
ALA A 502
ILE A 562
1.16A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
LEU A 498
ALA A 502
ILE A 562
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
LEU A 758
ALA A 580
ILE A 579
1.38A
None
A  T  13 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
LEU A 883
ALA A 866
ILE A 837
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
LEU A 514
ALA A 502
ILE A 562
1.17A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
LEU A 749
ALA A 699
ILE A 696
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TGM_A_AINA202_1
(PHOSPHOLIPASE A2)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
LEU A 437
ALA A 840
ILE A 548
1.21A
None
U  P  18 ( 3.4A)
None