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SIMILAR PATTERN OF AMINO ACIDS MAPPED TO UNIPROT ID 'T2B9R0'
| DrReposER ID / Desc. | Drug | Hit PDBID |
Hit Macromolecule |
Res. Matches |
View | Interface | RMSD | Seq. Identity (%) |
HETATM | Dock | |
|---|---|---|---|---|---|---|---|---|---|---|---|
 Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4K50_A_ACTA506_0 (RNA POLYMERASE3D-POL) | Acetic acid | 4ud1 | N PROTEIN (MERS-CoV) | 3 / 3 | VAL D 121GLY D 119LYS D 117 | 1.09A | 15.74 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3Q70_A_RITA2001_2 (CANDIDAPEPSIN-2) | Ritonavir | 4ud1 | N PROTEIN (MERS-CoV) | 4 / 6 | ILE D 120TYR D 77ASP D 130THR D 134 | 1.42A | 19.35 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5X24_A_LSNA503_1 (CYTOCHROME P450 2C9) | Losartan | 4ud1 | N PROTEIN (MERS-CoV) | 4 / 6 | PRO E 152GLY E 153THR E 154LYS E 155 | 1.01A | 15.06 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2PGR_A_DCFA501_2 (ADENOSINE DEAMINASE) | Pentostatin | 4ud1 | N PROTEIN (MERS-CoV) | 3 / 3 | LEU D 47LEU D 65PHE D 57 | 1.32A | 16.28 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2AVV_A_MK1A901_2 (POL POLYPROTEIN) | Indinavir | 4ud1 | N PROTEIN (MERS-CoV) | 3 / 3 | ASP D 130VAL B 121PRO B 54 | 1.34A | 23.90 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2AVV_A_MK1A901_2 (POL POLYPROTEIN) | Indinavir | 4ud1 | N PROTEIN (MERS-CoV) | 3 / 3 | ASP E 130VAL D 121PRO D 54 | 1.35A | 23.90 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6BAA_E_GBME2001_2 (ATP-BINDING CASSETTESUB-FAMILY C MEMBER8) | Glyburide | 4ud1 | N PROTEIN (MERS-CoV) | 3 / 3 | LEU C 111THR C 40ASN C 38 | 1.38A | 6.97 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5X24_A_LSNA503_1 (CYTOCHROME P450 2C9) | Losartan | 4ud1 | N PROTEIN (MERS-CoV) | 4 / 6 | PRO A 152GLY A 153THR A 154LYS A 155 | 1.02A | 15.06 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2PGR_A_DCFA501_2 (ADENOSINE DEAMINASE) | Pentostatin | 4ud1 | N PROTEIN (MERS-CoV) | 3 / 3 | LEU A 47LEU A 65PHE A 57 | 1.33A | 16.28 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2PGR_A_DCFA501_2 (ADENOSINE DEAMINASE) | Pentostatin | 4ud1 | N PROTEIN (MERS-CoV) | 3 / 3 | LEU B 156LEU B 65PHE B 57 | 0.79A | 16.28 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6BAA_E_GBME2001_2 (ATP-BINDING CASSETTESUB-FAMILY C MEMBER8) | Glyburide | 4ud1 | N PROTEIN (MERS-CoV) | 3 / 3 | LEU B 111THR B 40ASN B 38 | 1.39A | 6.97 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5NY7_A_NCAA303_0 (AMIDASE) | Nicotinamide | 4ud1 | N PROTEIN (MERS-CoV) | 4 / 6 | GLY E 106PRO E 107THR E 137SER E 42 | 1.45A | 20.45 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5X24_A_LSNA503_1 (CYTOCHROME P450 2C9) | Losartan | 4ud1 | N PROTEIN (MERS-CoV) | 4 / 6 | PRO D 152GLY D 153THR D 154LYS D 155 | 1.00A | 15.06 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2PGR_A_DCFA501_2 (ADENOSINE DEAMINASE) | Pentostatin | 4ud1 | N PROTEIN (MERS-CoV) | 3 / 3 | LEU D 156LEU D 65PHE D 57 | 0.85A | 16.28 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5X24_A_LSNA503_1 (CYTOCHROME P450 2C9) | Losartan | 4ud1 | N PROTEIN (MERS-CoV) | 4 / 6 | PRO B 152GLY B 153THR B 154LYS B 155 | 0.94A | 15.06 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2PGR_A_DCFA501_2 (ADENOSINE DEAMINASE) | Pentostatin | 4ud1 | N PROTEIN (MERS-CoV) | 3 / 3 | LEU A 156LEU A 65PHE A 57 | 0.86A | 16.28 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2PGR_A_DCFA501_2 (ADENOSINE DEAMINASE) | Pentostatin | 4ud1 | N PROTEIN (MERS-CoV) | 3 / 3 | LEU C 156LEU C 65PHE C 57 | 0.80A | 16.28 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3Q70_A_RITA2001_2 (CANDIDAPEPSIN-2) | Ritonavir | 4ud1 | N PROTEIN (MERS-CoV) | 4 / 6 | ILE E 120TYR E 77ASP E 130THR E 134 | 1.44A | 19.35 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4WQ4_B_ACTB403_0 (TRNA N6-ADENOSINETHREONYLCARBAMOYLTRANSFERASE) | Acetic acid | 4ud1 | N PROTEIN (MERS-CoV) | 3 / 3 | ARG A 83ASP A 82ARG A 80 | 1.08A | 17.10 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2PGR_A_DCFA501_2 (ADENOSINE DEAMINASE) | Pentostatin | 4ud1 | N PROTEIN (MERS-CoV) | 3 / 3 | LEU E 156LEU E 65PHE E 57 | 0.82A | 16.28 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6BAA_E_GBME2001_2 (ATP-BINDING CASSETTESUB-FAMILY C MEMBER8) | Glyburide | 4ud1 | N PROTEIN (MERS-CoV) | 3 / 3 | LEU A 111THR A 40ASN A 38 | 1.40A | 6.97 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4WQ4_B_ACTB403_0 (TRNA N6-ADENOSINETHREONYLCARBAMOYLTRANSFERASE) | Acetic acid | 4ud1 | N PROTEIN (MERS-CoV) | 3 / 3 | ARG C 83ASP C 82ARG C 80 | 1.06A | 17.10 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6N91_A_DCFA401_1 (ADENOSINE DEAMINASE) | Pentostatin | 4ud1 | N PROTEIN (MERS-CoV) | 4 / 4 | HIS E 124LEU D 111TYR D 77GLY D 119 | 1.44A | 18.66 | NH4 E1164 (-3.7A)NoneNoneNone | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2AVV_A_MK1A901_2 (POL POLYPROTEIN) | Indinavir | 4ud1 | N PROTEIN (MERS-CoV) | 3 / 3 | ASP C 130VAL A 121PRO A 54 | 1.34A | 23.90 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3Q70_A_RITA2001_2 (CANDIDAPEPSIN-2) | Ritonavir | 4ud1 | N PROTEIN (MERS-CoV) | 4 / 6 | ILE B 120TYR B 77ASP B 130THR B 134 | 1.43A | 19.35 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2AVV_A_MK1A901_2 (POL POLYPROTEIN) | Indinavir | 4ud1 | N PROTEIN (MERS-CoV) | 3 / 3 | ASP B 130VAL C 121PRO C 54 | 1.33A | 23.90 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3Q70_A_RITA2001_2 (CANDIDAPEPSIN-2) | Ritonavir | 4ud1 | N PROTEIN (MERS-CoV) | 4 / 6 | ILE A 120TYR A 77ASP A 130THR A 134 | 1.44A | 19.35 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4FOR_A_FLPA711_1 (LACTOTRANSFERRIN) | Flurbiprofen | 4ud1 | N PROTEIN (MERS-CoV) | 4 / 7 | THR D 154GLY D 62VAL D 123PRO D 64 | 1.48A | 19.17 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5NY7_A_NCAA303_0 (AMIDASE) | Nicotinamide | 4ud1 | N PROTEIN (MERS-CoV) | 4 / 6 | GLY A 106PRO A 107THR A 137SER A 42 | 1.44A | 20.45 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3Q70_A_RITA2001_2 (CANDIDAPEPSIN-2) | Ritonavir | 4ud1 | N PROTEIN (MERS-CoV) | 4 / 6 | ILE C 120TYR C 77ASP C 130THR C 134 | 1.43A | 19.35 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5X24_A_LSNA503_1 (CYTOCHROME P450 2C9) | Losartan | 4ud1 | N PROTEIN (MERS-CoV) | 4 / 6 | PRO C 152GLY C 153THR C 154LYS C 155 | 0.96A | 15.06 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1W0G_A_MYTA1499_1 (CYTOCHROME P450 3A4) | Metyrapone | 4ud1 | N PROTEIN (MERS-CoV) | 4 / 6 | ARG C 114ILE A 120THR A 56ALA B 131 | 1.49A | 15.26 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5K4P_A_SORA611_0 (PROBABLEPHOSPHATIDYLETHANOLAMINE TRANSFERASEMCR-1) | Sorbitol | 4ud1 | N PROTEIN (MERS-CoV) | 4 / 6 | GLY D 106THR D 105TYR D 101GLY D 136 | 1.49A | 20.44 | None |