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| PDB ID: 2og3 Macromolecule: NUCLEOCAPSID PROTEIN Source Organism: SARS-COV Tor2 Gene names: N UniProt ID: P59595 |
SIMILAR PATTERN OF AMINO ACIDS MAPPED TO PDBID '2og3'
1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.| DrReposER ID / Desc. | Drug | Res. Matches |
View | Interface | RMSD | Seq. Identity (%) |
HETATM | Dock | |
|---|---|---|---|---|---|---|---|---|---|
 Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5N0W_A_SAMA501_0 (PEPTIDEN-METHYLTRANSFERASE) | S-Adenosylmethionine | 6 / 12 | ILE A 85TYR A 124GLY A 86PHE A 67VAL A 132ALA A 139 | 1.66A | 15.09 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4NJU_A_TPVA500_2 (PROTEASE) | Tipranavir | 5 / 10 | LEU A 140ALA A 135GLY A 125THR A 142ILE A 85 | 1.33A | 25.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QN9_B_DXCB610_0 (N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D) | Deoxycholic Acid | 3 / 3 | GLY A 80PRO A 81ALA A 139 | 1.09A | 15.28 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5CXV_A_0HKA501_2 (MUSCARINICACETYLCHOLINERECEPTORM1,ENDOLYSIN,MUSCARINIC ACETYLCHOLINERECEPTOR M1) | Tiotropium | 3 / 3 | THR A 158THR A 55PHE A 111 | 0.91A | 14.96 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4PD9_A_ADNA501_1 (NUPC FAMILY PROTEIN) | Adenosine | 5 / 12 | GLN A 84ALA A 135TYR A 88ASN A 76SER A 79 | 1.59A | 12.50 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3KP6_B_SALB3007_1 (TRANSCRIPTIONALREGULATOR TCAR) | Salicylic acid | 5 / 9 | ASN A 155THR A 158ALA A 157ALA A 51SER A 52 | 1.50A | 19.38 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2GSS_A_EAAA0_1 (GLUTATHIONES-TRANSFERASE P1-1) | Etacrynic acid | 4 / 8 | TYR A 88PHE A 67VAL A 134ILE A 75 | 1.41A | 21.03 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OU7_A_SAMA300_0 (SAM-DEPENDENTMETHYLTRANSFERASE) | S-Adenosylmethionine | 5 / 12 | LEU A 162TYR A 113GLY A 86GLY A 72LEU A 65 | 1.75A | 19.53 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4A99_C_MIYC391_1 (TETX2 PROTEIN) | Minocycline | 5 / 11 | ASN A 76GLN A 84GLY A 80SER A 79GLY A 115 | 1.69A | 18.72 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6AG0_A_ACRA608_0 (ALPHA-AMYLASE) | Acarbose | 4 / 6 | GLY A 72THR A 136GLN A 84TYR A 113 | 1.63A | 13.52 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3JVY_B_017B401_2 (GAG-POL POLYPROTEIN) | Darunavir | 6 / 12 | GLY A 138ALA A 139ASP A 82ASP A 83VAL A 134ILE A 85 | 1.75A | 20.71 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ECE_C_DVAC3010_0 (VLM2DODECADEPSIPEPTIDE) | L-Valine | 3 / 3 | ALA A 56PHE A 172GLN A 59 | 1.20A | 18.95 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2OCU_A_TYLA3001_1 (LACTOTRANSFERRIN) | Acetaminophen | 3 / 3 | LEU A 65TYR A 88GLY A 86 | 0.69A | 17.54 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2FXE_A_DR7A102_1 (POL PROTEIN) | Atazanavir | 5 / 12 | GLY A 115GLY A 125ILE A 131VAL A 73ILE A 85 | 1.34A | 22.06 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2DR2_A_TRPA479_0 (TRYPTOPHANYL-TRNASYNTHETASE) | L-Tryptophan | 5 / 11 | TYR A 113GLY A 138THR A 136GLN A 84ILE A 147 | 1.44A | 15.30 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4PD5_A_GEOA501_1 (NUPC FAMILY PROTEIN) | Gemcitabine | 6 / 12 | GLN A 84ALA A 135VAL A 134TYR A 88ASN A 76SER A 79 | 1.73A | 12.50 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5N0O_A_SAMA501_0 (PEPTIDEN-METHYLTRANSFERASE) | S-Adenosylmethionine | 6 / 12 | ILE A 85TYR A 124GLY A 86PHE A 67VAL A 132ALA A 139 | 1.62A | 15.52 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2VCD_A_RAPA138_1 (OUTER MEMBRANEPROTEIN MIP) | Sirolimus | 5 / 11 | TYR A 113ASP A 83PHE A 54GLN A 161PRO A 163 | 1.52A | 22.97 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4A6E_A_SAMA1349_0 (HYDROXYINDOLEO-METHYLTRANSFERASE) | S-Adenosylmethionine | 5 / 12 | GLY A 72GLY A 70ILE A 85PHE A 111ARG A 66 | 1.55A | 16.18 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3NS1_L_PM6L1_1 (XANTHINEDEHYDROGENASE/OXIDASE) | Mercaptopurine | 4 / 8 | ARG A 69LEU A 114ALA A 139ALA A 135 | 1.23A | 10.06 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ZIF_A_SAMA298_0 (PUTATIVEMODIFICATIONMETHYLASE) | S-Adenosylmethionine | 5 / 12 | ALA A 139PRO A 68PHE A 67GLY A 70GLU A 137 | 1.48A | 19.05 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2AZX_A_TRPA601_0 (TRYPTOPHANYL-TRNASYNTHETASE) | L-Tryptophan | 5 / 12 | TYR A 113GLY A 138THR A 136GLN A 84ILE A 147 | 1.43A | 12.50 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6FEK_A_ADNA1104_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE RECEPTOR RET) | Adenosine | 6 / 11 | GLY A 148ILE A 85VAL A 73TYR A 87GLY A 115LEU A 114 | 1.62A | 19.19 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5NY7_A_NCAA303_0 (AMIDASE) | Nicotinamide | 4 / 6 | GLY A 117PRO A 118THR A 149SER A 52 | 1.43A | 21.22 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1GWR_A_ESTA600_1 (OESTROGEN RECEPTOR) | Estradiol | 5 / 10 | LEU A 160LEU A 162ALA A 174LEU A 168LEU A 65 | 1.72A | 19.07 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y6O_A_1N1A1892_1 (EPHRIN TYPE-ARECEPTOR 4) | Dasatinib | 5 / 12 | ALA A 126LYS A 128GLU A 119ILE A 131SER A 121 | 0.99A | 18.21 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2VQ5_B_LDPB1197_1 (S-NORCOCLAURINESYNTHASE) | Dopamine | 4 / 7 | LEU A 57LEU A 168PHE A 67PRO A 163 | 1.16A | 23.08 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ICT_D_T44D129_2 (TRANSTHYRETIN) | Levothyroxine | 4 / 7 | THR A 55LEU A 105SER A 106THR A 58 | 1.11A | 20.98 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3G1U_B_ADNB438_1 (ADENOSYLHOMOCYSTEINASE) | Adenosine | 5 / 12 | THR A 166GLN A 71LEU A 160LEU A 162GLY A 72 | 1.56A | 15.10 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3FPJ_B_SAMB301_1 (PUTATIVEUNCHARACTERIZEDPROTEIN) | S-Adenosylmethionine | 4 / 7 | GLY A 61GLY A 171THR A 58GLU A 63 | 1.03A | 19.08 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6EW0_G_TA1G501_2 (TUBULIN BETA CHAIN) | Paclitaxel | 4 / 6 | LEU A 162LEU A 65THR A 55PRO A 118 | 1.35A | 12.81 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6F8C_A_STRA502_1 (CYTOCHROME P450CYP260A1) | Progesterone | 4 / 6 | ALA A 139GLY A 115THR A 116PHE A 54 | 0.94A | 16.45 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1IGX_A_EPAA700_1 (PROSTAGLANDINENDOPEROXIDE HSYNTHASE-1) | Icosapent | 6 / 12 | PHE A 54PHE A 111TYR A 113GLY A 86ALA A 135GLY A 72 | 1.55A | 12.45 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ZXW_P_CHDP1271_0 (CYTOCHROME C OXIDASEPOLYPEPTIDE 7A1CYTOCHROME C OXIDASESUBUNIT 3) | Cholic Acid | 4 / 6 | LEU A 160PHE A 111LEU A 57PHE A 172 | 1.60A | 21.8123.15 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3P2K_A_SAMA6735_0 (16S RRNA METHYLASE) | S-Adenosylmethionine | 5 / 12 | GLY A 171GLY A 61THR A 167LEU A 168TRP A 109 | 1.48A | 17.84 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2FN1_A_SALA506_1 (SALICYLATESYNTHETASE, IRP9) | Salicylic acid | 5 / 11 | ILE A 85GLU A 137GLY A 72ARG A 69GLY A 86 | 1.78A | 17.39 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5N0X_B_SAMB501_0 (PEPTIDEN-METHYLTRANSFERASE) | S-Adenosylmethionine | 6 / 12 | ILE A 85TYR A 124GLY A 86PHE A 67VAL A 132ALA A 139 | 1.67A | 15.09 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2QO5_A_CHDA131_0 (LIVER-BASIC FATTYACID BINDING PROTEIN) | Cholic Acid | 5 / 12 | ILE A 75THR A 136VAL A 132PHE A 111LEU A 162 | 1.61A | 21.09 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5EML_A_SAMA701_0 (PROTEIN ARGININEN-METHYLTRANSFERASE5) | S-Adenosylmethionine | 5 / 12 | PRO A 169LEU A 168GLY A 61GLU A 64LEU A 65 | 1.48A | 13.58 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3BVB_B_017B401_2 (PROTEASE(RETROPEPSIN)) | Darunavir | 6 / 12 | GLY A 138ALA A 139ASP A 82ASP A 83VAL A 134ILE A 85 | 1.76A | 23.53 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1TSN_A_C2FA266_0 (THYMIDYLATE SYNTHASE) | Levomefolic acid | 6 / 12 | HIS A 146ILE A 147LEU A 114GLY A 115TYR A 124ALA A 135 | 1.78A | 18.05 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5I9X_A_DB8A1001_1 (EPHRIN TYPE-ARECEPTOR 2) | Bosutinib | 5 / 12 | ALA A 126LYS A 128GLU A 119ILE A 131SER A 121 | 0.98A | 19.27 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4TWP_A_AXIA601_1 (TYROSINE-PROTEINKINASE ABL1) | Axitinib | 5 / 12 | LEU A 122TYR A 87ALA A 126GLY A 115LEU A 114 | 1.52A | 18.45 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1FE2_A_LAXA700_2 (PROSTAGLANDINENDOPEROXIDE HSYNTHASE-1) | Dihomo-gamma-linolenic acid | 6 / 12 | PHE A 54PHE A 111TYR A 113GLY A 86ALA A 135GLY A 72 | 1.58A | 12.45 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1GTI_F_CCSF47_0 (GLUTATHIONES-TRANSFERASE) | Carbocisteine | 4 / 5 | THR A 116LEU A 122GLY A 86TYR A 87 | 1.71A | 17.79 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6B58_A_ACTA608_0 (FUMARATE REDUCTASEFLAVOPROTEIN SUBUNIT) | Acetic acid | 3 / 3 | GLY A 70THR A 136GLU A 137 | 1.63A | 12.76 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ACB_C_DXCC1478_0 (TRANSLATIONELONGATION FACTORSELB) | Deoxycholic Acid | 4 / 6 | SER A 52THR A 116THR A 158PHE A 54 | 1.38A | 14.78 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4O5F_A_PAUA301_0 (TYPE IIIPANTOTHENATE KINASE) | Pantothenic acid | 5 / 12 | VAL A 73LEU A 114GLY A 86ILE A 147THR A 116 | 1.40A | 21.05 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2AXN_A_EDTA737_0 (6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BIPHOSPHATASE 3(6PF-2-K/FRU-2,6-P2ASEBRAIN/PLACENTA-TYPEISOZYME) (IPFK-2)[INCLUDES: 6-PHOSPHOFRUCTO-2-KINASE (EC 2.7.1.105) FRUCTOSE-2,6-BISPHOSPHATASE (EC3.1.3.46)]) | Edetic Acid | 5 / 12 | PRO A 74GLY A 70PHE A 67ALA A 135TYR A 88 | 1.74A | 14.59 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1LQT_B_ACTB1874_0 (FPRA) | Acetic acid | 4 / 5 | ALA A 157PHE A 54SER A 52TRP A 53 | 1.48A | 14.82 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5SYJ_A_NIZA810_1 (CATALASE-PEROXIDASE) | Isoniazid | 4 / 6 | ARG A 150LEU A 160PRO A 74SER A 52 | 1.79A | 10.55 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4K50_A_ACTA506_0 (RNA POLYMERASE3D-POL) | Acetic acid | 3 / 3 | VAL A 132GLY A 130LYS A 128 | 1.05A | 14.79 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4LG1_C_SAMC301_0 (PROTEIN-LYSINEMETHYLTRANSFERASEMETTL21D) | S-Adenosylmethionine | 5 / 12 | TRP A 133GLY A 130LEU A 65TYR A 87TYR A 112 | 1.68A | 19.66 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4CP4_A_CAMA416_0 (CYTOCHROME P450-CAM) | Camphor | 4 / 7 | TYR A 88THR A 55LEU A 168VAL A 159 | 1.44A | 14.25 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2O4K_A_DR7A301_2 (PROTEASE) | Atazanavir | 5 / 12 | GLY A 138ALA A 139ASP A 82VAL A 134ILE A 85 | 1.37A | 23.53 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2COI_A_GBNA420_1 (BRANCHED CHAINAMINOTRANSFERASE 1,CYTOSOLIC) | Gabapentin | 5 / 10 | TYR A 124GLY A 70THR A 136ALA A 135VAL A 132 | 1.42A | 16.27 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MZE_A_CFXA364_1 (D-ALANYL-D-ALANINECARBOXYPEPTIDASEDACA) | Cefoxitin | 5 / 12 | ALA A 139GLY A 125ASN A 141LEU A 114GLY A 138 | 1.53A | 19.55 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2DXR_A_SORA1002_0 (LACTOTRANSFERRIN) | Sorbitol | 3 / 3 | THR A 50PRO A 118TYR A 112 | 1.45A | 17.54 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3N9J_A_EAAA210_1 (GLUTATHIONES-TRANSFERASE P) | Etacrynic acid | 4 / 8 | TYR A 88PHE A 67VAL A 134ILE A 75 | 1.35A | 21.43 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4PB1_A_RBVA501_1 (NUPC FAMILY PROTEIN) | Ribavirin | 5 / 12 | GLN A 84ALA A 135TYR A 88ASN A 76SER A 79 | 1.57A | 12.50 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4P65_C_IPHC101_0 (INSULIN) | Phenol | 5 / 11 | LEU A 57LEU A 160ALA A 174LEU A 168VAL A 73 | 1.19A | 24.0012.30 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3V4T_A_ACTA504_0 (UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE) | Acetic acid | 3 / 3 | THR A 136VAL A 134GLU A 137 | 1.34A | 14.43 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5IY5_P_CHDP307_0 (CYTOCHROME C OXIDASESUBUNIT 3CYTOCHROME C OXIDASESUBUNIT 7A1,MITOCHONDRIAL) | Cholic Acid | 4 / 5 | LEU A 160PHE A 111LEU A 57PHE A 172 | 1.60A | 21.4018.66 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1LIK_A_ADNA799_1 (ADENOSINE KINASE) | Adenosine | 5 / 10 | GLY A 70VAL A 134VAL A 73ALA A 139GLN A 84 | 1.37A | 19.89 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5VYH_A_FOLA409_0 (S PROTEIN) | Folic Acid | 5 / 10 | TRP A 133ARG A 69ALA A 135GLY A 86ILE A 85 | 1.38A | 17.61 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3VYW_C_SAMC401_0 (MNMC2) | S-Adenosylmethionine | 5 / 12 | GLY A 72GLY A 70ALA A 174PHE A 111LEU A 57 | 1.04A | 17.82 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4EJG_B_NCTB501_1 (CYTOCHROME P450 2A13) | Nicotine | 5 / 8 | PHE A 111PHE A 54ASN A 76THR A 136LEU A 160 | 1.70A | 15.34 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3P2K_B_SAMB6735_0 (16S RRNA METHYLASE) | S-Adenosylmethionine | 5 / 12 | GLY A 171GLY A 61THR A 167LEU A 168TRP A 109 | 1.42A | 17.84 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3NY4_A_SMXA310_1 (BETA-LACTAMASE) | Cefamandole | 5 / 8 | LEU A 65ARG A 90ALA A 91GLY A 171PRO A 169 | 1.72A | 17.60 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MB5_A_NMYA301_0 (AAC(3)-IIIB PROTEIN) | Framycetin | 5 / 11 | ASN A 76TYR A 112ASP A 83THR A 149GLY A 148 | 1.76A | 18.38 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4XUM_A_IMNA501_1 (PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR GAMMA) | Indomethacin | 5 / 12 | PHE A 67ILE A 75LEU A 168LEU A 57LEU A 160 | 1.52A | 17.42 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ACA_B_DXCB1473_0 (TRANSLATIONELONGATION FACTORSELB) | Deoxycholic Acid | 5 / 9 | VAL A 134THR A 136GLN A 71GLY A 70ARG A 66 | 1.28A | 14.78 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2AKE_A_TRPA479_0 (TRYPTOPHANYL-TRNASYNTHETASE) | L-Tryptophan | 5 / 12 | TYR A 113GLY A 138THR A 136GLN A 84ILE A 147 | 1.44A | 15.30 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5XDX_C_CHDC308_0 (CYTOCHROME C OXIDASESUBUNIT 3CYTOCHROME C OXIDASESUBUNIT VIIA-HEART) | Cholic Acid | 4 / 5 | LEU A 160PHE A 111LEU A 57PHE A 172 | 1.68A | 21.4023.15 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1EA1_A_TPFA470_1 (CYTOCHROME P45051-LIKE RV0764C) | Fluconazole | 4 / 8 | PHE A 111ARG A 69PHE A 67THR A 166 | 1.35A | 15.86 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3SO9_A_017A100_2 (HIV-1 PROTEASE) | Darunavir | 5 / 12 | ALA A 139ASP A 82ASP A 83PRO A 163VAL A 73 | 1.38A | 23.57 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4FO4_B_MOAB502_1 (INOSINE5'-MONOPHOSPHATEDEHYDROGENASE) | Mycophenolic acid | 4 / 8 | SER A 79GLY A 138THR A 136GLY A 86 | 1.10A | 17.49 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6FNM_A_1N1A1001_1 (-) | Dasatinib | 5 / 12 | ALA A 126LYS A 128GLU A 119ILE A 131SER A 121 | 1.00A | 20.34 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4Z3O_F_MFXF101_1 (DNA TOPOISOMERASE 4SUBUNITB,PARE30-PARC55FUSED TOPO IV FROMS. PNEUMONIAEE-SITE DNA) | Moxifloxacin | 4 / 5 | ARG A 150ARG A 89GLY A 117GLU A 119 | 1.47A | 11.07 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1AXW_A_MTXA732_1 (THYMIDYLATE SYNTHASE) | Methotrexate | 6 / 12 | HIS A 146ILE A 147LEU A 114GLY A 115TYR A 124ALA A 135 | 1.78A | 18.05 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2A1H_A_GBNA502_1 (BRANCHED CHAINAMINOTRANSFERASE) | Gabapentin | 4 / 8 | GLY A 70THR A 136ALA A 135VAL A 132 | 1.13A | 16.13 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5X1F_C_CHDC304_0 (CYTOCHROME C OXIDASESUBUNIT 3CYTOCHROME C OXIDASESUBUNIT 7A1,MITOCHONDRIAL) | Cholic Acid | 4 / 5 | LEU A 160PHE A 111LEU A 57PHE A 172 | 1.64A | 21.8123.15 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2FXE_A_DR7A102_2 (POL PROTEIN) | Atazanavir | 5 / 11 | GLY A 138ALA A 139ASP A 82VAL A 134ILE A 85 | 1.34A | 22.06 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1I2W_A_CFXA1300_2 (BETA-LACTAMASE) | Cefoxitin | 4 / 5 | TYR A 88PRO A 169THR A 136ARG A 69 | 1.72A | 19.47 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5L6E_B_ACTB401_0 (N6-ADENOSINE-METHYLTRANSFERASE 70 KDASUBUNITN6-ADENOSINE-METHYLTRANSFERASE SUBUNITMETTL14) | Acetic acid | 4 / 6 | GLU A 64ARG A 90LEU A 65ARG A 66 | 1.36A | 20.2819.48 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5N0X_A_SAMA501_0 (PEPTIDEN-METHYLTRANSFERASE) | S-Adenosylmethionine | 6 / 12 | ILE A 85TYR A 124GLY A 86PHE A 67VAL A 132ALA A 139 | 1.66A | 15.09 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4Y0P_A_TE4A201_1 (BETA-LACTOGLOBULIN) | Tetracaine | 5 / 12 | LEU A 114LEU A 65ILE A 131LEU A 160PHE A 111 | 1.29A | 23.21 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2BFP_A_H4BA1290_1 (PTERIDINE REDUCTASE1) | Sapropterin | 4 / 8 | SER A 79TYR A 113LEU A 160LEU A 162 | 1.15A | 17.45 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3VYW_A_SAMA501_0 (MNMC2) | S-Adenosylmethionine | 5 / 12 | TYR A 113GLY A 72ALA A 174PHE A 111LEU A 57 | 1.66A | 17.82 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1H4O_A_BEZA1162_0 (PEROXIREDOXIN 5) | Benzoic Acid | 5 / 10 | PRO A 169THR A 167LEU A 57ARG A 66GLY A 72 | 1.61A | 20.12 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4G1B_A_ECNA403_1 (FLAVOHEMOGLOBIN) | Econazole | 5 / 12 | PHE A 172ALA A 56LEU A 57LEU A 65ILE A 131 | 1.35A | 16.25 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Z97_A_CAMA422_0 (CYTOCHROME P450-CAM) | Camphor | 4 / 6 | THR A 166LEU A 168VAL A 134VAL A 132 | 1.36A | 14.46 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4P65_I_IPHI101_0 (INSULIN) | Phenol | 5 / 12 | VAL A 73LEU A 168LEU A 57LEU A 160ALA A 174 | 1.24A | 12.3024.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ZIF_B_SAMB298_0 (PUTATIVEMODIFICATIONMETHYLASE) | S-Adenosylmethionine | 5 / 12 | ALA A 120SER A 52PHE A 54GLY A 86LEU A 122 | 1.19A | 19.05 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1AO8_A_MTXA170_1 (DIHYDROFOLATEREDUCTASE) | Methotrexate | 5 / 12 | THR A 166PHE A 67LEU A 65ALA A 174THR A 158 | 1.47A | 20.22 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2M2P_B_DHIB24_0 (INSULIN B CHAIN) | L-Histidine | 3 / 3 | TYR A 113GLY A 117PHE A 111 | 1.71A | 14.16 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OU7_C_SAMC300_1 (SAM-DEPENDENTMETHYLTRANSFERASE) | S-Adenosylmethionine | 3 / 3 | GLY A 80ASP A 83ASP A 145 | 0.67A | 19.53 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1AFS_A_TESA325_1 (3-ALPHA-HYDROXYSTEROID DEHYDROGENASE) | Testosterone | 4 / 7 | TYR A 88THR A 149ASN A 76TYR A 113 | 1.59A | 15.95 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3T8N_D_EDTD135_0 (STEROIDDELTA-ISOMERASE) | Edetic Acid | 5 / 11 | PRO A 143THR A 116GLY A 117PRO A 118ASP A 145 | 1.70A | 22.58 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5N0O_B_SAMB501_0 (PEPTIDEN-METHYLTRANSFERASE) | S-Adenosylmethionine | 6 / 12 | ILE A 85TYR A 124GLY A 86PHE A 67VAL A 132ALA A 139 | 1.64A | 15.52 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2WX2_A_TPFA1460_1 (LANOSTEROL14-ALPHA-DEMETHYLASE) | Fluconazole | 4 / 7 | TYR A 113ALA A 135THR A 166LEU A 162 | 1.38A | 16.34 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4OBW_C_SAMC601_0 (2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOLMETHYLASE,MITOCHONDRIAL) | S-Adenosylmethionine | 5 / 12 | ASN A 155GLY A 148GLY A 86ASN A 76PHE A 111 | 1.63A | 19.19 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1E7C_A_HLTA4007_1 (SERUM ALBUMIN) | Halothane | 4 / 8 | TYR A 113LEU A 57PHE A 111LEU A 160 | 1.29A | 11.35 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3V3O_C_T1CC401_1 (TETX2 PROTEIN) | Tigecycline | 5 / 11 | ASN A 76GLN A 84GLY A 80SER A 79GLY A 115 | 1.76A | 17.13 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1LQU_A_ACTA1428_0 (FPRA) | Acetic acid | 4 / 7 | ALA A 157PHE A 54SER A 52TRP A 53 | 1.49A | 14.82 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4EJG_A_NCTA501_1 (CYTOCHROME P450 2A13) | Nicotine | 5 / 7 | PHE A 111PHE A 54ASN A 76THR A 136LEU A 160 | 1.79A | 15.34 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4DXU_A_ACAA711_1 (LACTOTRANSFERRIN) | Aminocaproic Acid | 4 / 6 | GLY A 86VAL A 134GLY A 138GLU A 137 | 1.36A | 18.04 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2UVN_A_ECNA1409_1 (CYTOCHROME P450 130) | Econazole | 5 / 12 | LEU A 65PRO A 169THR A 167GLY A 165LEU A 57 | 1.40A | 15.56 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1LQU_B_ACTB1431_0 (FPRA) | Acetic acid | 4 / 5 | ALA A 157PHE A 54SER A 52TRP A 53 | 1.48A | 14.82 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2QD2_A_CHDA2_0 (FERROCHELATASE) | Cholic Acid | 4 / 8 | LEU A 168ARG A 66PRO A 74VAL A 134 | 1.53A | 16.28 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4K13_A_ETSA304_1 (CARBONIC ANHYDRASE 2) | Dorzolamide | 5 / 12 | HIS A 60LEU A 162LEU A 160LEU A 57THR A 58 | 1.47A | 20.08 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ESW_A_ACRA652_1 (AMYLOMALTASE) | Acarbose | 4 / 6 | TYR A 112GLY A 117GLY A 148TYR A 113 | 1.36A | 16.87 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4O0U_A_ADNA501_1 (AURORA KINASE A) | Adenosine | 4 / 6 | VAL A 134LEU A 160THR A 166LEU A 162 | 1.13A | 20.63 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1SG9_A_SAMA301_0 (HEMK PROTEIN) | S-Adenosylmethionine | 5 / 12 | ILE A 85GLY A 80ILE A 147GLU A 137ASN A 76 | 1.54A | 17.95 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3FSU_A_C2FA995_0 (5,10-METHYLENETETRAHYDROFOLATE REDUCTASE) | Levomefolic acid | 5 / 12 | THR A 55LEU A 65LEU A 168THR A 166TYR A 88 | 1.36A | 21.07 | None | ||
 Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2D55_C_DVAC2_0 (ACTINOMYCIN D) | L-Valine | 3 / 3 | THR A 167PRO A 169PRO A 68 | 1.41A | 40.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HUP_D_DZPD2001_0 (GAMMA-AMINOBUTYRICACID RECEPTORSUBUNITALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTORSUBUNIT ALPHA-1GAMMA-AMINOBUTYRICACID RECEPTORSUBUNIT GAMMA-2) | Diazepam | 5 / 9 | ASN A 76PHE A 54TYR A 88SER A 52TYR A 112 | 1.70A | 14.3418.50 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1BZF_A_TMQA170_1 (DIHYDROFOLATEREDUCTASE) | Trimetrexate | 5 / 12 | THR A 166PHE A 67LEU A 65ALA A 174THR A 158 | 1.47A | 20.22 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4EJG_C_NCTC501_1 (CYTOCHROME P450 2A13) | Nicotine | 5 / 7 | PHE A 111PHE A 54ASN A 76LEU A 162LEU A 160 | 1.65A | 15.34 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2QD3_A_CHDA502_0 (FERROCHELATASE) | Cholic Acid | 4 / 8 | ARG A 69SER A 52VAL A 73GLY A 72 | 1.36A | 15.70 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1TKQ_B_DVAB8_0 (GRAMICIDIN A) | L-Valine | 4 / 5 | VAL A 134GLY A 86VAL A 73TRP A 53 | 1.45A | 7.52 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1MX1_E_THAE5_2 (LIVERCARBOXYLESTERASE I) | Tacrine | 3 / 3 | PHE A 67LEU A 57LEU A 160 | 0.92A | 15.04 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5X2T_I_PEMI202_1 (HEMOGLOBIN SUBUNITALPHAHEMOGLOBIN SUBUNITBETA) | Bezafibrate | 4 / 8 | ALA A 120THR A 50TRP A 133ALA A 91 | 1.33A | 19.7521.25 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3EL0_A_1UNA201_1 (PROTEASE) | Nelfinavir | 4 / 8 | GLY A 138ASP A 82ASP A 83PRO A 163 | 0.95A | 23.08 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3KHM_A_TPFA501_1 (STEROL 14ALPHA-DEMETHYLASE) | Fluconazole | 4 / 8 | TYR A 113ALA A 135THR A 166LEU A 162 | 1.25A | 16.20 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5B8H_A_PAUA302_0 (TYPE IIIPANTOTHENATE KINASE) | Pantothenic acid | 5 / 12 | VAL A 73LEU A 114GLY A 86ILE A 147THR A 116 | 1.42A | 19.59 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6C2M_D_SUED1202_0 (NS3 PROTEASE) | Grazoprevir | 5 / 12 | GLY A 86VAL A 132GLY A 148ARG A 89ALA A 51 | 1.32A | 21.43 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4KLR_B_CHDB504_0 (FERROCHELATASE,MITOCHONDRIAL) | Cholic Acid | 3 / 3 | LEU A 162PRO A 163ARG A 69 | 1.04A | 16.12 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4P65_A_IPHA101_0 (INSULIN) | Phenol | 5 / 10 | LEU A 162LEU A 168ALA A 174LEU A 65LEU A 160 | 1.52A | 24.0012.30 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4AE1_A_NCAA1536_0 (DIPHTHERIA TOXIN) | Nicotinamide | 4 / 6 | GLY A 125TYR A 87ALA A 126GLU A 119 | 1.37A | 15.22 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 11GS_A_EAAA211_1 (GLUTATHIONES-TRANSFERASE) | Etacrynic acid | 4 / 7 | TYR A 88PHE A 67VAL A 134ILE A 75 | 1.40A | 21.43 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QWP_A_GCSA301_1 (CHITOSANASE) | Glucosamine | 3 / 3 | TYR A 87GLY A 117PRO A 118 | 1.27A | 20.33 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2WX2_B_TPFB1460_1 (LANOSTEROL14-ALPHA-DEMETHYLASE) | Fluconazole | 4 / 8 | TYR A 113ALA A 135THR A 166LEU A 162 | 1.32A | 16.34 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3KVR_A_URFA2001_1 (URIDINEPHOSPHORYLASE) | Fluorouracil | 5 / 10 | GLY A 115PHE A 111GLU A 119LEU A 114ILE A 85 | 1.54A | 17.80 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5N0R_A_SAMA501_0 (PEPTIDEN-METHYLTRANSFERASE) | S-Adenosylmethionine | 6 / 12 | ILE A 85TYR A 124GLY A 86PHE A 67VAL A 132ALA A 139 | 1.67A | 15.09 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6EW0_F_TA1F502_2 (TUBULIN BETA CHAIN) | Paclitaxel | 4 / 5 | LEU A 162LEU A 65THR A 55PRO A 118 | 1.35A | 12.81 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5D75_A_FK5A301_1 (PEPTIDYL-PROLYLCIS-TRANS ISOMERASEFKBP3) | Tacrolimus | 5 / 11 | LEU A 162TYR A 124ALA A 139ILE A 85PHE A 111 | 1.58A | 20.14 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1LQT_A_ACTA1871_0 (FPRA) | Acetic acid | 4 / 7 | ALA A 157PHE A 54SER A 52TRP A 53 | 1.49A | 14.82 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4BWL_C_MN9C1297_0 (N-ACETYLNEURAMINATELYASE) | N-Acetyl-D-glucosamine | 5 / 10 | ILE A 147THR A 116GLY A 117SER A 52PHE A 54 | 1.45A | 20.33 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4EJG_D_NCTD501_1 (CYTOCHROME P450 2A13) | Nicotine | 4 / 6 | PHE A 111PHE A 54ASN A 76THR A 136 | 1.32A | 15.34 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4G2Z_A_ID8A711_1 (LACTOTRANSFERRIN) | Mefenamic acid | 3 / 3 | PRO A 74TYR A 88GLY A 86 | 0.94A | 18.04 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3VYW_D_SAMD401_0 (MNMC2) | S-Adenosylmethionine | 5 / 12 | TYR A 113GLY A 72ALA A 174PHE A 111LEU A 57 | 1.61A | 17.82 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ZMQ_I_PACI1_0 (SERINE PROTEASE NS3SERINE PROTEASESUBUNIT NS2BPEPTIDEPAC-DLY-DLY-DAR) | Phenylacetic acid | 3 / 3 | VAL A 132TYR A 88GLU A 64 | 1.18A | 21.9516.91 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4A6D_A_SAMA1350_0 (HYDROXYINDOLEO-METHYLTRANSFERASE) | S-Adenosylmethionine | 6 / 12 | TYR A 124GLY A 72GLY A 70ILE A 85PHE A 111ARG A 66 | 1.75A | 16.18 | None |