POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	1ch4	MODULE-SUBSTITUTED CHIMERA HEMOGLOBIN BETA-ALPHA (Homo sapiens)	5 / 12	LEU A  81 ALA A 135 SER A 129 LEU A 130 LEU A   3	None	1.09A	19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	1cjy	PROTEIN (CYTOSOLIC PHOSPHOLIPASE A2) (Homo sapiens)	5 / 12	LEU A 341 ALA A 486 SER A 398 LEU A 400 MET A 417	None	1.18A	15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	1fns	VON WILLEBRAND FACTOR (Homo sapiens)	5 / 12	LEU A 519 LEU A 621 ALA A 623 SER A 679 LEU A 677	None	0.98A	21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	1lbk	GLUTATHIONE S-TRANSFERASE CLASS PI CHIMAERA (CODA) (Homo sapiens)	5 / 12	LEU A 158 LEU A 155 ASN A 154 ALA A 151 LEU A 132	None	1.16A	18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	1mi1	NEUROBEACHIN (Homo sapiens)	5 / 12	LEU A2290 LEU A2293 ASN A2294 ALA A2297 LEU A2546	None	0.53A	23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	1pcg	ESTROGEN RECEPTOR (Homo sapiens)	5 / 12	LEU A 346 ALA A 350 TRP A 383 LEU A 391 MET A 421	EST  A   1 (-4.4A) EST  A   1 ( 3.7A) None EST  A   1 ( 3.9A) EST  A   1 ( 4.3A)	0.67A	25.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	1t77	LIPOPOLYSACCHARIDE-R ESPONSIVE AND BEIGE-LIKE ANCHOR PROTEIN (Homo sapiens)	5 / 12	LEU A2226 LEU A2229 ASN A2230 ALA A2233 LEU A2482	None	0.52A	23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	1x9d	ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHA RIDE 1,2-ALPHA-MANNOSIDAS E (Homo sapiens)	5 / 12	LEU A 336 LEU A 339 ALA A 342 SER A 349 LEU A 350	None	1.11A	19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	1xb7	STEROID HORMONE RECEPTOR ERR1 (Homo sapiens)	5 / 12	LEU A 327 LEU A 324 ALA A 396 LEU A 401 LEU A 380	None	1.16A	28.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	2ax9	ANDROGEN RECEPTOR (Homo sapiens)	8 / 12	LEU A 701 LEU A 704 ASN A 705 TRP A 741 MET A 742 MET A 780 MET A 787 LEU A 873	None BHM  A   1 (-4.0A) BHM  A   1 (-3.6A) None BHM  A   1 ( 4.0A) BHM  A   1 ( 4.3A) BHM  A   1 (-3.6A) BHM  A   1 (-4.4A)	1.23A	44.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	3kba	PROGESTERONE RECEPTOR (Homo sapiens)	7 / 12	LEU A 715 LEU A 718 ASN A 719 TRP A 755 MET A 756 LEU A 763 LEU A 887	WOW  A   1 (-3.9A) WOW  A   1 (-4.2A) WOW  A   1 (-3.3A) None WOW  A   1 ( 4.1A) WOW  A   1 ( 4.0A) WOW  A   1 (-4.0A)	0.94A	51.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	3rbl	AROMATIC L-AMINO ACID DECARBOXYLASE (Homo sapiens)	5 / 12	LEU A 222 ALA A 216 SER A 250 LEU A 243 MET A 239	None	1.23A	20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	4kng	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 (Homo sapiens)	5 / 12	LEU A 143 LEU A 167 ALA A 190 SER A 211 LEU A 209	None	1.23A	20.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	4p6w	GLUCOCORTICOID RECEPTOR (Homo sapiens)	6 / 12	LEU A 563 ASN A 564 TRP A 600 MET A 601 LEU A 608 LEU A 732	MOF  A 801 (-3.9A) MOF  A 801 (-3.0A) None MOF  A 801 (-3.7A) MOF  A 801 ( 4.6A) MOF  A 801 ( 4.2A)	0.53A	52.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	4qik	ROQUIN-1 (Homo sapiens)	5 / 12	LEU A 183 SER A 305 SER A 304 LEU A 307 MET A 317	None CL  A 505 (-3.7A) None None None	1.11A	22.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	4udb	MINERALOCORTICOID RECEPTOR (Homo sapiens)	7 / 12	ALA A 773 TRP A 806 MET A 807 SER A 811 LEU A 814 MET A 852 LEU A 938	CV7  A1987 (-3.5A) None CV7  A1987 ( 3.9A) None CV7  A1987 ( 4.0A) CV7  A1987 ( 3.7A) CV7  A1987 ( 3.9A)	0.72A	99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	4udb	MINERALOCORTICOID RECEPTOR (Homo sapiens)	9 / 12	LEU A 766 LEU A 769 ASN A 770 ALA A 773 TRP A 806 MET A 807 SER A 811 LEU A 814 LEU A 938	CV7  A1987 (-3.6A) CV7  A1987 (-4.1A) CV7  A1987 (-3.1A) CV7  A1987 (-3.5A) None CV7  A1987 ( 3.9A) None CV7  A1987 ( 4.0A) CV7  A1987 ( 3.9A)	0.33A	99.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	4yub	NICOTINATE PHOSPHORIBOSYLTRANSF ERASE (Homo sapiens)	5 / 12	LEU A 121 LEU A 109 SER A 493 LEU A 496 LEU A  56	None	1.13A	18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	4zlc	ROQUIN-2 (Homo sapiens)	5 / 12	LEU A 180 SER A 302 SER A 301 LEU A 304 MET A 314	None	1.12A	19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	5bv8	VON WILLEBRAND FACTOR (Homo sapiens)	5 / 12	LEU A1282 LEU A1384 ALA A1386 SER A1442 LEU A1440	None	0.95A	20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	5kij	ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHA RIDE 1,2-ALPHA-MANNOSIDAS E (Homo sapiens)	5 / 12	LEU A 336 LEU A 339 ALA A 342 SER A 349 LEU A 350	None	1.18A	21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	5mwp	MINERALOCORTICOID RECEPTOR (Homo sapiens)	11 / 12	LEU A 766 LEU A 769 ASN A 770 ALA A 773 TRP A 806 MET A 807 SER A 810 LEU A 814 MET A 845 MET A 852 LEU A 938	ECV  A1101 ( 3.9A) ECV  A1101 (-4.7A) ECV  A1101 (-3.1A) ECV  A1101 (-3.8A) None ECV  A1101 (-3.6A) ECV  A1101 (-3.4A) ECV  A1101 (-4.1A) ECV  A1101 (-4.0A) ECV  A1101 (-3.7A) ECV  A1101 ( 4.3A)	0.42A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	5mwp	MINERALOCORTICOID RECEPTOR (Homo sapiens)	11 / 12	LEU A 766 LEU A 769 ASN A 770 ALA A 773 TRP A 806 MET A 807 SER A 811 LEU A 814 MET A 845 MET A 852 LEU A 938	ECV  A1101 ( 3.9A) ECV  A1101 (-4.7A) ECV  A1101 (-3.1A) ECV  A1101 (-3.8A) None ECV  A1101 (-3.6A) ECV  A1101 (-3.0A) ECV  A1101 (-4.1A) ECV  A1101 (-4.0A) ECV  A1101 (-3.7A) ECV  A1101 ( 4.3A)	0.42A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	5toa	ESTROGEN RECEPTOR BETA (Homo sapiens)	5 / 12	LEU A 298 ALA A 302 TRP A 335 MET A 336 LEU A 343	EST  A 601 (-4.1A) EST  A 601 ( 3.9A) None EST  A 601 ( 3.7A) EST  A 601 ( 4.4A)	0.57A	26.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_0 (MINERALOCORTICOID RECEPTOR)	6c3p	ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8 (Homo sapiens)	5 / 12	LEU E 318 SER E 581 SER E 579 LEU E 582 LEU E 456	None	1.20A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_1 (MINERALOCORTICOID RECEPTOR)	1wer	P120GAP (Homo sapiens)	4 / 6	ARG A 776 CYH A1002 THR A1030 PHE A 726	None	1.42A	23.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MWY_A_YNUA1101_1 (MINERALOCORTICOID RECEPTOR)	2ax9	ANDROGEN RECEPTOR (Homo sapiens)	4 / 6	GLN A 711 ARG A 752 PHE A 764 PHE A 891	BHM  A   1 (-2.2A) BHM  A   1 (-3.8A) BHM  A   1 (-4.4A) None	0.54A	44.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_1 (MINERALOCORTICOID RECEPTOR)	2cw6	HYDROXYMETHYLGLUTARY L-COA LYASE, MITOCHONDRIAL (Homo sapiens)	4 / 6	PHE A 147 CYH A 170 THR A 205 PHE A 134	None	1.47A	22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_1 (MINERALOCORTICOID RECEPTOR)	3ibj	CGMP-DEPENDENT 3',5'-CYCLIC PHOSPHODIESTERASE (Homo sapiens)	4 / 6	GLN A 463 PHE A 433 THR A 499 PHE A 487	None	1.22A	19.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MWY_A_YNUA1101_1 (MINERALOCORTICOID RECEPTOR)	3kba	PROGESTERONE RECEPTOR (Homo sapiens)	6 / 6	GLN A 725 ARG A 766 PHE A 778 CYH A 891 THR A 894 PHE A 905	WOW  A   1 ( 4.1A) WOW  A   1 (-3.8A) None WOW  A   1 (-3.5A) WOW  A   1 (-3.9A) WOW  A   1 (-4.6A)	0.74A	51.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_1 (MINERALOCORTICOID RECEPTOR)	4hwt	THREONINE--TRNA LIGASE, CYTOPLASMIC (Homo sapiens)	4 / 6	GLN A 599 PHE A 572 CYH A 450 PHE A 499	None	1.43A	21.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MWY_A_YNUA1101_1 (MINERALOCORTICOID RECEPTOR)	4p6w	GLUCOCORTICOID RECEPTOR (Homo sapiens)	6 / 6	GLN A 570 ARG A 611 PHE A 623 CYH A 736 THR A 739 PHE A 749	MOF  A 801 (-2.9A) MOF  A 801 (-4.2A) MOF  A 801 (-4.7A) MOF  A 801 (-3.7A) MOF  A 801 (-3.9A) MOF  A 801 (-4.4A)	0.36A	52.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MWY_A_YNUA1101_1 (MINERALOCORTICOID RECEPTOR)	4udb	MINERALOCORTICOID RECEPTOR (Homo sapiens)	6 / 6	GLN A 776 ARG A 817 PHE A 829 CYH A 942 THR A 945 PHE A 956	CV7  A1987 (-3.0A) CV7  A1987 (-3.7A) CV7  A1987 (-4.9A) CV7  A1987 (-4.0A) CV7  A1987 (-3.1A) CV7  A1987 ( 4.7A)	0.26A	99.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_1 (MINERALOCORTICOID RECEPTOR)	5j97	CAPRIN-2 (Homo sapiens)	4 / 6	PHE A 314 CYH A 262 THR A 261 PHE A 282	None	1.43A	23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_1 (MINERALOCORTICOID RECEPTOR)	5mwp	MINERALOCORTICOID RECEPTOR (Homo sapiens)	6 / 6	GLN A 776 ARG A 817 PHE A 829 CYH A 942 THR A 945 PHE A 956	ECV  A1101 (-2.9A) ECV  A1101 (-4.0A) ECV  A1101 ( 4.9A) ECV  A1101 (-4.0A) ECV  A1101 (-3.2A) ECV  A1101 ( 4.7A)	0.27A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_1 (MINERALOCORTICOID RECEPTOR)	5mwp	MINERALOCORTICOID RECEPTOR (Homo sapiens)	4 / 6	PHE A 835 CYH A 942 THR A 945 PHE A 956	None ECV  A1101 (-4.0A) ECV  A1101 (-3.2A) ECV  A1101 ( 4.7A)	1.14A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_1 (MINERALOCORTICOID RECEPTOR)	6bhc	PSEUDOPODIUM-ENRICHE D ATYPICAL KINASE 1 (Homo sapiens)	4 / 6	GLN A1664 PHE A1730 CYH A1305 PHE A1706	None	1.38A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_1 (MINERALOCORTICOID RECEPTOR)	6c0t	CGMP-DEPENDENT PROTEIN KINASE 1 (Homo sapiens)	4 / 6	ARG A 453 PHE A 456 CYH A 467 PHE A 622	None	1.48A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWY_A_YNUA1101_1 (MINERALOCORTICOID RECEPTOR)	6f0x	MAD2L1-BINDING PROTEIN (Homo sapiens)	4 / 6	GLN P 179 PHE P  60 CYH P  74 PHE P 142	None	1.08A	undetectable