POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	1h4l	CELL DIVISION PROTEIN KINASE 5 (Homo sapiens)	6 / 12	ALA A  31 LYS A  33 VAL A  64 PHE A  82 CYH A  83 LEU A 133	None	0.56A	28.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	1rjb	FL CYTOKINE RECEPTOR (Homo sapiens)	9 / 12	LEU A 616 GLY A 617 ALA A 642 LYS A 644 VAL A 675 CYH A 694 GLY A 697 LEU A 818 CYH A 828	None	0.60A	51.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	1s9i	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	LEU A  78 GLY A  79 ALA A  99 LYS A 101 GLY A 153 LEU A 201 CYH A 211	ATP  A 535 (-3.9A) ATP  A 535 ( 3.9A) ATP  A 535 (-3.6A) ATP  A 535 ( 2.5A) ATP  A 535 ( 4.7A) ATP  A 535 (-4.8A) ATP  A 535 ( 4.5A)	0.83A	23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	1s9i	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	LEU A  78 GLY A  79 ALA A  99 VAL A 131 GLY A 153 LEU A 201 CYH A 211	ATP  A 535 (-3.9A) ATP  A 535 ( 3.9A) ATP  A 535 (-3.6A) 5EA  A1001 (-4.5A) ATP  A 535 ( 4.7A) ATP  A 535 (-4.8A) ATP  A 535 ( 4.5A)	0.67A	23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	1t46	HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG (Homo sapiens)	10 / 12	LEU A 595 GLY A 596 GLU A 605 ALA A 621 LYS A 623 VAL A 654 CYH A 673 GLY A 676 LEU A 799 CYH A 809	STI  A   3 ( 3.8A) None None STI  A   3 (-3.5A) STI  A   3 (-3.7A) STI  A   3 (-4.3A) STI  A   3 (-4.5A) STI  A   3 ( 3.8A) STI  A   3 (-4.4A) STI  A   3 (-4.5A)	0.79A	53.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	1u59	TYROSINE-PROTEIN KINASE ZAP-70 (Homo sapiens)	6 / 12	LEU A 344 GLY A 345 ALA A 367 VAL A 399 GLY A 420 LEU A 468	STU  A 100 (-3.8A) STU  A 100 (-3.3A) STU  A 100 (-3.2A) None STU  A 100 (-3.5A) STU  A 100 (-4.5A)	0.48A	33.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	1zlt	SERINE/THREONINE-PRO TEIN KINASE CHK1 (Homo sapiens)	8 / 12	LEU A  15 GLY A  16 ALA A  36 LYS A  38 VAL A  68 CYH A  87 GLY A  90 LEU A 137	HYM  A 400 (-4.2A) HYM  A 400 ( 3.8A) HYM  A 400 (-3.5A) HYM  A 400 (-3.2A) HYM  A 400 (-4.8A) HYM  A 400 (-4.2A) None HYM  A 400 (-4.5A)	0.61A	26.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2buj	SERINE/THREONINE-PRO TEIN KINASE 16 (Homo sapiens)	7 / 12	LEU A  26 GLY A  27 ALA A  47 LYS A  49 PHE A 100 GLY A 104 LEU A 155	STU  A1301 (-4.2A) STU  A1301 ( 3.8A) STU  A1301 (-3.6A) STU  A1301 ( 4.0A) STU  A1301 (-4.5A) STU  A1301 ( 4.0A) STU  A1301 ( 4.8A)	0.71A	23.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	7 / 12	LEU X  17 GLY X  18 ALA X  37 LYS X  39 VAL X  67 GLY X  88 LEU X 137	STU  X 902 (-3.8A) STU  X 902 ( 3.7A) STU  X 902 (-3.1A) STU  X 902 (-3.1A) None STU  X 902 (-3.5A) STU  X 902 (-4.4A)	0.67A	33.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2eu9	DUAL SPECIFICITY PROTEIN KINASE CLK3 (Homo sapiens)	7 / 12	LEU A 162 GLU A 172 ALA A 184 LYS A 186 VAL A 220 GLY A 240 LEU A 290	None	1.05A	24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2eu9	DUAL SPECIFICITY PROTEIN KINASE CLK3 (Homo sapiens)	7 / 12	LEU A 162 GLY A 163 GLU A 172 ALA A 184 LYS A 186 VAL A 220 LEU A 290	None	0.71A	24.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	7 / 12	LEU A 273 GLY A 274 ALA A 293 LYS A 295 PHE A 340 GLY A 344 LEU A 393	QUE  A   1 (-3.9A) QUE  A   1 ( 4.2A) QUE  A   1 (-3.5A) None QUE  A   1 (-4.2A) QUE  A   1 (-3.0A) QUE  A   1 (-4.4A)	0.94A	34.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2hck	HEMATOPOETIC CELL KINASE HCK (Homo sapiens)	7 / 12	LEU A 273 GLY A 274 ALA A 293 VAL A 323 PHE A 340 GLY A 344 LEU A 393	QUE  A   1 (-3.9A) QUE  A   1 ( 4.2A) QUE  A   1 (-3.5A) None QUE  A   1 (-4.2A) QUE  A   1 (-3.0A) QUE  A   1 (-4.4A)	0.76A	34.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2hk5	TYROSINE-PROTEIN KINASE HCK (Homo sapiens)	8 / 12	LEU A 251 GLY A 252 ALA A 271 LYS A 273 VAL A 301 PHE A 318 GLY A 322 LEU A 371	1BM  A 499 ( 3.7A) None 1BM  A 499 (-3.6A) 1BM  A 499 (-3.8A) None 1BM  A 499 (-4.1A) 1BM  A 499 (-3.5A) 1BM  A 499 (-4.4A)	0.83A	39.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2hw6	MAP KINASE-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 1 (Homo sapiens)	6 / 12	LEU A  55 GLY A  56 ALA A  76 GLY A 130 LEU A 177 CYH A 190	None	0.57A	26.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	9 / 12	LEU A 248 GLY A 249 GLU A 258 ALA A 269 LYS A 271 VAL A 299 PHE A 317 GLY A 321 LEU A 370	GIN  A 600 ( 4.6A) None None GIN  A 600 (-3.1A) GIN  A 600 (-3.6A) GIN  A 600 (-4.6A) GIN  A 600 (-4.3A) None GIN  A 600 (-4.7A)	0.62A	37.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2ogv	MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR PRECURSOR (Homo sapiens)	9 / 12	LEU A 588 GLY A 589 GLU A 598 ALA A 614 LYS A 616 VAL A 647 CYH A 666 GLY A 669 LEU A 785	None	0.56A	51.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2ozo	TYROSINE-PROTEIN KINASE ZAP-70 (Homo sapiens)	7 / 12	LEU A 344 GLY A 345 ALA A 367 LYS A 369 VAL A 399 GLY A 419 LEU A 468	ANP  A 615 (-4.4A) ANP  A 615 ( 4.4A) ANP  A 615 (-3.3A) ANP  A 615 (-3.1A) None None ANP  A 615 (-4.7A)	0.84A	22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2ozo	TYROSINE-PROTEIN KINASE ZAP-70 (Homo sapiens)	7 / 12	LEU A 344 GLY A 345 ALA A 367 LYS A 369 VAL A 399 GLY A 420 LEU A 468	ANP  A 615 (-4.4A) ANP  A 615 ( 4.4A) ANP  A 615 (-3.3A) ANP  A 615 (-3.1A) None ANP  A 615 ( 3.9A) ANP  A 615 (-4.7A)	0.92A	22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2z7r	RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 (Homo sapiens)	8 / 12	LEU A  68 GLY A  69 ALA A  92 LYS A  94 VAL A 125 PHE A 143 GLY A 147 LEU A 194	STU  A   1 (-3.8A) STU  A   1 (-3.3A) STU  A   1 (-3.3A) STU  A   1 (-2.8A) None STU  A   1 (-4.6A) STU  A   1 ( 3.9A) STU  A   1 (-4.6A)	0.65A	29.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	2z8c	INSULIN RECEPTOR (Homo sapiens)	6 / 12	LEU A1002 GLY A1003 GLU A1012 ALA A1028 LYS A1030 VAL A1060	S91  A   1 ( 4.1A) S91  A   1 ( 3.9A) None S91  A   1 (-3.2A) S91  A   1 ( 4.2A) None	0.61A	36.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3b2t	FIBROBLAST GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	7 / 12	LEU A 487 GLY A 488 ALA A 515 LYS A 517 VAL A 564 GLY A 570 LEU A 633	M33  A1996 (-4.0A) M33  A1996 ( 3.8A) M33  A1996 (-3.3A) M33  A1996 ( 4.5A) None M33  A1996 ( 4.8A) M33  A1996 (-4.5A)	0.63A	53.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3fzp	PROTEIN TYROSINE KINASE 2 BETA (Homo sapiens)	8 / 12	LEU A 431 GLY A 432 GLU A 441 ALA A 455 LYS A 457 VAL A 487 GLY A 508 LEU A 556	AGS  A 999 ( 4.4A) AGS  A 999 ( 4.2A) None AGS  A 999 (-3.6A) AGS  A 999 (-2.5A) None None AGS  A 999 (-4.5A)	0.65A	34.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3hng	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	9 / 12	LEU A 833 GLY A 834 ALA A 859 LYS A 861 VAL A 892 VAL A 909 CYH A 912 GLY A 915 LEU A1029	8ST  A2001 ( 4.7A) None 8ST  A2001 ( 3.8A) 8ST  A2001 (-4.0A) 8ST  A2001 ( 4.7A) 8ST  A2001 (-4.1A) 8ST  A2001 (-3.8A) None None	0.47A	67.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3hng	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	9 / 12	LEU A 833 GLY A 834 ALA A 859 VAL A 892 VAL A 909 CYH A 912 GLY A 915 LEU A1029 CYH A1039	8ST  A2001 ( 4.7A) None 8ST  A2001 ( 3.8A) 8ST  A2001 ( 4.7A) 8ST  A2001 (-4.1A) 8ST  A2001 (-3.8A) None None 8ST  A2001 (-4.2A)	0.60A	67.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3mi9	CELL DIVISION PROTEIN KINASE 9 (Homo sapiens)	6 / 12	ALA A  46 LYS A  48 VAL A  79 PHE A 105 CYH A 106 LEU A 156	None	0.59A	26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3nuu	PKB-LIKE (Homo sapiens)	6 / 12	LEU A  88 GLY A  89 ALA A 109 LYS A 111 GLY A 165 LEU A 212	JOZ  A 361 (-4.1A) JOZ  A 361 ( 4.3A) JOZ  A 361 (-3.4A) SO4  A   5 (-2.8A) None None	0.59A	25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	7 / 12	LEU A 192 GLY A 193 ALA A 213 LYS A 215 VAL A 247 GLY A 269 LEU A 318	AMP  A 577 ( 4.3A) AMP  A 577 ( 3.7A) AMP  A 577 (-3.4A) AMP  A 577 (-2.8A) None None AMP  A 577 (-4.8A)	0.73A	22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3she	MAP KINASE-ACTIVATED PROTEIN KINASE 3 (Homo sapiens)	8 / 12	LEU A  50 GLY A  51 GLU A  60 ALA A  71 LYS A  73 VAL A  98 GLY A 124 LEU A 173	I85  A 350 (-3.7A) I85  A 350 (-3.5A) None I85  A 350 (-3.3A) I85  A 350 (-2.8A) None I85  A 350 (-3.0A) None	0.84A	23.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3tt0	BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	7 / 12	LEU A 484 GLY A 485 ALA A 512 LYS A 514 VAL A 561 GLY A 567 LEU A 630	07J  A   1 ( 4.3A) 07J  A   1 ( 4.9A) 07J  A   1 (-3.5A) 07J  A   1 (-4.5A) 07J  A   1 (-4.7A) 07J  A   1 (-3.7A) 07J  A   1 ( 4.4A)	0.66A	48.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3txo	PROTEIN KINASE C ETA TYPE (Homo sapiens)	6 / 12	LEU A 361 GLY A 362 ALA A 382 PHE A 435 GLY A 439 LEU A 486	07U  A   1 ( 4.8A) 07U  A   1 ( 4.2A) 07U  A   1 (-3.3A) None None 07U  A   1 (-4.3A)	0.45A	23.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3vid	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	7 / 12	LEU A 840 GLY A 841 GLU A 850 ALA A 866 LYS A 868 VAL A 916 PHE A 918	4TT  A2001 ( 4.0A) 4TT  A2001 ( 4.8A) None 4TT  A2001 (-3.5A) None None 4TT  A2001 (-4.5A)	0.71A	85.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3vid	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	11 / 12	LEU A 840 GLY A 841 GLU A 850 ALA A 866 VAL A 899 VAL A 916 PHE A 918 CYH A 919 GLY A 922 LEU A1035 CYH A1045	4TT  A2001 ( 4.0A) 4TT  A2001 ( 4.8A) None 4TT  A2001 (-3.5A) None None 4TT  A2001 (-4.5A) 4TT  A2001 (-4.3A) 4TT  A2001 (-3.7A) 4TT  A2001 (-4.8A) None	0.46A	85.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3wig	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1 (Homo sapiens)	7 / 12	LEU A  75 GLY A  76 ALA A  96 LYS A  98 VAL A 128 GLY A 149 LEU A 198	ANP  A 401 (-3.8A) ANP  A 401 ( 3.7A) ANP  A 401 (-3.2A) ANP  A 401 (-2.7A) CHU  A 403 (-4.2A) None ANP  A 401 (-4.8A)	0.90A	24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3wig	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1 (Homo sapiens)	8 / 12	LEU A  75 GLY A  76 ALA A  96 LYS A  98 VAL A 128 GLY A 150 LEU A 198 CYH A 208	ANP  A 401 (-3.8A) ANP  A 401 ( 3.7A) ANP  A 401 (-3.2A) ANP  A 401 (-2.7A) CHU  A 403 (-4.2A) ANP  A 401 ( 4.3A) ANP  A 401 (-4.8A) CHU  A 403 ( 3.7A)	1.10A	24.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	10 / 12	LEU A 840 GLU A 850 ALA A 866 VAL A 899 VAL A 916 PHE A 918 CYH A 919 GLY A 922 LEU A1035 CYH A1045	LEV  A1201 ( 3.8A) None LEV  A1201 (-3.5A) None LEV  A1201 ( 4.6A) LEV  A1201 (-4.7A) LEV  A1201 (-4.1A) LEV  A1201 (-3.6A) LEV  A1201 (-4.8A) GOL  A1210 ( 3.3A)	0.47A	99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	10 / 12	LEU A 840 GLY A 841 GLU A 850 ALA A 866 VAL A 899 VAL A 916 PHE A 918 CYH A 919 LEU A1035 CYH A1045	LEV  A1201 ( 3.8A) LEV  A1201 (-3.1A) None LEV  A1201 (-3.5A) None LEV  A1201 ( 4.6A) LEV  A1201 (-4.7A) LEV  A1201 (-4.1A) LEV  A1201 (-4.8A) GOL  A1210 ( 3.3A)	0.81A	99.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	3zdu	CYCLIN-DEPENDENT KINASE-LIKE 3 (Homo sapiens)	7 / 12	GLY A  11 ALA A  31 LYS A  33 VAL A  63 PHE A  81 LEU A 132 CYH A 142	38R  A 350 ( 3.9A) 38R  A 350 (-3.4A) 38R  A 350 (-2.9A) 38R  A 350 ( 4.9A) 38R  A 350 (-4.2A) 38R  A 350 (-4.3A) 38R  A 350 ( 3.9A)	0.69A	27.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4a4l	SERINE/THREONINE-PRO TEIN KINASE PLK1 (Homo sapiens)	6 / 12	LEU A  59 GLY A  60 ALA A  80 LYS A  82 VAL A 114 CYH A 133	939  A1331 (-3.7A) 939  A1331 ( 4.7A) 939  A1331 (-3.5A) 939  A1331 (-2.6A) None 939  A1331 (-4.0A)	0.53A	27.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4agd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	12 / 12	LEU A 840 GLY A 841 GLU A 850 ALA A 866 LYS A 868 VAL A 899 VAL A 916 PHE A 918 CYH A 919 GLY A 922 LEU A1035 CYH A1045	B49  A2000 (-3.7A) B49  A2000 ( 4.6A) None B49  A2000 (-3.5A) B49  A2000 (-3.0A) B49  A2000 ( 4.6A) B49  A2000 (-4.8A) B49  A2000 (-4.4A) B49  A2000 (-4.2A) B49  A2000 ( 3.7A) B49  A2000 (-4.5A) B49  A2000 ( 4.1A)	0.62A	89.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4agu	CYCLIN-DEPENDENT KINASE-LIKE 1 (Homo sapiens)	7 / 12	GLY A  11 ALA A  31 LYS A  33 VAL A  64 CYH A  83 LEU A 133 CYH A 143	D15  A 500 (-3.8A) D15  A 500 (-3.4A) D15  A 500 ( 4.1A) None D15  A 500 (-4.3A) D15  A 500 (-4.5A) D15  A 500 ( 4.0A)	0.53A	27.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4aw5	EPHRIN TYPE-B RECEPTOR 4 (Homo sapiens)	6 / 12	GLY A  98 ALA A 121 LYS A 123 PHE A 171 GLY A 175 LEU A 223	30K  A1365 ( 3.9A) 30K  A1365 (-3.2A) 30K  A1365 (-3.8A) 30K  A1365 (-4.4A) 30K  A1365 (-3.5A) 30K  A1365 (-4.5A)	0.58A	32.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4b6l	SERINE/THREONINE-PRO TEIN KINASE PLK3 (Homo sapiens)	6 / 12	LEU A  68 GLY A  69 ALA A  89 LYS A  91 VAL A 123 CYH A 142	9ZP  A1333 (-3.9A) 9ZP  A1333 (-3.6A) 9ZP  A1333 (-3.5A) None 9ZP  A1333 (-4.4A) 9ZP  A1333 (-4.1A)	0.58A	25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4bc6	SERINE/THREONINE-PRO TEIN KINASE 10 (Homo sapiens)	8 / 12	LEU A  42 GLY A  43 ALA A  63 VAL A  94 PHE A 112 CYH A 113 GLY A 116 LEU A 164	XZN  A1317 (-3.6A) XZN  A1317 ( 4.9A) XZN  A1317 (-3.5A) XZN  A1317 (-4.4A) XZN  A1317 (-4.5A) XZN  A1317 (-3.7A) XZN  A1317 ( 3.7A) XZN  A1317 (-4.7A)	0.60A	27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4crs	SERINE/THREONINE-PRO TEIN KINASE N2 (Homo sapiens)	6 / 12	LEU A 663 ALA A 684 LYS A 686 VAL A 721 GLY A 743 LEU A 789	AGS  A1985 (-4.2A) AGS  A1985 (-3.5A) AGS  A1985 (-3.0A) None None AGS  A1985 (-4.8A)	0.60A	24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4eut	SERINE/THREONINE-PRO TEIN KINASE TBK1 (Homo sapiens)	8 / 12	LEU A  15 GLY A  16 ALA A  36 LYS A  38 VAL A  68 PHE A  88 CYH A  89 GLY A  92	BX7  A 401 (-3.7A) BX7  A 401 ( 3.7A) BX7  A 401 (-3.4A) BX7  A 401 ( 4.0A) None BX7  A 401 ( 4.6A) BX7  A 401 (-4.1A) BX7  A 401 (-3.5A)	0.69A	21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4euu	SERINE/THREONINE-PRO TEIN KINASE TBK1 (Homo sapiens)	7 / 12	LEU A  15 GLY A  16 ALA A  36 LYS A  38 PHE A  88 CYH A  89 GLY A  92	BX7  A 401 (-3.9A) BX7  A 401 ( 3.8A) BX7  A 401 (-3.4A) BX7  A 401 (-3.5A) BX7  A 401 ( 4.6A) BX7  A 401 (-4.1A) BX7  A 401 (-3.3A)	0.72A	25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4euu	SERINE/THREONINE-PRO TEIN KINASE TBK1 (Homo sapiens)	7 / 12	LEU A  15 GLY A  16 ALA A  36 VAL A  68 PHE A  88 CYH A  89 GLY A  92	BX7  A 401 (-3.9A) BX7  A 401 ( 3.8A) BX7  A 401 (-3.4A) None BX7  A 401 ( 4.6A) BX7  A 401 (-4.1A) BX7  A 401 (-3.3A)	0.41A	25.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4f4p	TYROSINE-PROTEIN KINASE SYK (Homo sapiens)	7 / 12	LEU A 377 GLY A 378 ALA A 400 LYS A 402 VAL A 433 GLY A 454 LEU A 501	0SB  A 701 ( 3.9A) 0SB  A 701 (-3.6A) 0SB  A 701 (-3.3A) 0SB  A 701 ( 4.8A) None 0SB  A 701 (-3.5A) 0SB  A 701 (-4.4A)	0.84A	34.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4fie	SERINE/THREONINE-PRO TEIN KINASE PAK 4 (Homo sapiens)	7 / 12	GLY A 328 ALA A 348 LYS A 350 VAL A 379 PHE A 397 GLY A 401 LEU A 447	ANP  A1001 (-4.4A) ANP  A1001 (-3.6A) ANP  A1001 (-3.0A) None ANP  A1001 ( 4.6A) None ANP  A1001 (-4.7A)	0.61A	24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4fl3	TYROSINE-PROTEIN KINASE SYK (Homo sapiens)	7 / 12	LEU A 377 GLY A 378 ALA A 400 LYS A 402 VAL A 433 GLY A 454 LEU A 501	ANP  A 701 ( 4.6A) ANP  A 701 ( 4.0A) ANP  A 701 (-3.3A) ANP  A 701 (-2.7A) ANP  A 701 (-4.8A) ANP  A 701 ( 4.2A) ANP  A 701 (-4.5A)	0.83A	22.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4fod	ALK TYROSINE KINASE RECEPTOR (Homo sapiens)	7 / 12	LEU A1122 GLU A1132 ALA A1148 LYS A1150 VAL A1180 GLY A1201 LEU A1256	0UV  A1501 (-3.8A) None 0UV  A1501 (-3.4A) 0UV  A1501 (-3.7A) 0UV  A1501 ( 4.9A) 0UV  A1501 (-4.4A) 0UV  A1501 (-4.6A)	1.08A	34.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4fod	ALK TYROSINE KINASE RECEPTOR (Homo sapiens)	8 / 12	LEU A1122 GLY A1123 GLU A1132 ALA A1148 LYS A1150 VAL A1180 GLY A1202 LEU A1256	0UV  A1501 (-3.8A) 0UV  A1501 ( 4.3A) None 0UV  A1501 (-3.4A) 0UV  A1501 (-3.7A) 0UV  A1501 ( 4.9A) 0UV  A1501 (-3.6A) 0UV  A1501 (-4.6A)	1.00A	34.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4fr4	SERINE/THREONINE-PRO TEIN KINASE 32A (Homo sapiens)	6 / 12	GLY A  30 ALA A  50 VAL A  84 VAL A 100 GLY A 106 LEU A 153	STU  A 401 (-3.3A) STU  A 401 (-3.2A) None None STU  A 401 ( 3.7A) STU  A 401 (-4.7A)	0.36A	25.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	7 / 12	LEU A 828 GLY A 829 ALA A 853 LYS A 855 VAL A 884 GLY A 908 LEU A 956	19S  A1201 (-3.9A) 19S  A1201 (-3.7A) 19S  A1201 (-3.3A) 19S  A1201 (-3.5A) None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.74A	33.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4hzs	ACTIVATED CDC42 KINASE 1 (Homo sapiens)	6 / 12	LEU A 132 GLY A 133 ALA A 156 LYS A 158 GLY A 211 LEU A 259	None	0.47A	31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4idt	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 14 (Homo sapiens)	7 / 12	LEU A 406 ALA A 427 LYS A 429 VAL A 453 GLY A 475 LEU A 522 CYH A 533	T28  A 701 (-3.8A) T28  A 701 (-3.0A) T28  A 701 ( 3.8A) None T28  A 701 ( 3.0A) T28  A 701 (-3.9A) T28  A 701 (-3.7A)	0.80A	25.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4k11	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Homo sapiens)	7 / 12	LEU A 273 GLY A 274 ALA A 293 LYS A 295 VAL A 323 GLY A 344 LEU A 393	0J9  A 601 (-4.0A) 0J9  A 601 ( 4.0A) 0J9  A 601 (-3.3A) 0J9  A 601 ( 4.7A) None 0J9  A 601 ( 4.1A) 0J9  A 601 (-4.5A)	0.87A	27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4ks8	SERINE/THREONINE-PRO TEIN KINASE PAK 6 (Homo sapiens)	7 / 12	GLY A 414 ALA A 434 LYS A 436 VAL A 465 PHE A 483 GLY A 487 LEU A 533	B49  A 701 ( 4.3A) B49  A 701 (-3.2A) None None B49  A 701 (-4.3A) B49  A 701 ( 3.7A) B49  A 701 (-4.5A)	0.73A	28.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4lg4	SERINE/THREONINE-PRO TEIN KINASE 3 (Homo sapiens)	8 / 12	LEU A  33 GLY A  34 ALA A  54 LYS A  56 VAL A  83 CYH A 102 GLY A 105 LEU A 153	GOL  A 404 ( 3.6A) None GOL  A 404 ( 3.1A) GOL  A 403 ( 4.6A) GOL  A 403 (-4.1A) GOL  A 403 (-4.0A) GOL  A 404 (-3.6A) GOL  A 403 ( 4.4A)	0.64A	26.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4o38	CYCLIN-G-ASSOCIATED KINASE (Homo sapiens)	9 / 12	LEU A  46 GLU A  56 ALA A  67 LYS A  69 VAL A  99 CYH A 126 GLY A 128 LEU A 180 CYH A 190	SIN  A 401 ( 3.9A) None SIN  A 401 ( 3.7A) None None SIN  A 401 (-4.3A) SIN  A 401 (-3.5A) SIN  A 401 ( 4.5A) None	0.72A	24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4otd	SERINE/THREONINE-PRO TEIN KINASE N1 (Homo sapiens)	6 / 12	LEU A 627 GLY A 628 ALA A 648 VAL A 685 GLY A 707 LEU A 753	None	0.59A	27.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4rt7	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	8 / 12	LEU A 616 GLY A 617 ALA A 642 LYS A 644 VAL A 675 CYH A 694 GLY A 697 LEU A 818	P30  A1001 (-3.8A) None P30  A1001 (-3.4A) P30  A1001 (-3.4A) None None P30  A1001 (-3.4A) P30  A1001 (-4.6A)	0.47A	45.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4rt7	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	8 / 12	LEU A 616 GLY A 617 ALA A 642 VAL A 675 CYH A 694 GLY A 697 LEU A 818 CYH A 828	P30  A1001 (-3.8A) None P30  A1001 (-3.4A) None None P30  A1001 (-3.4A) P30  A1001 (-4.6A) P30  A1001 (-4.1A)	0.55A	45.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4usf	STE20-LIKE SERINE/THREONINE-PRO TEIN KINASE (Homo sapiens)	7 / 12	LEU A  40 GLY A  41 ALA A  61 PHE A 110 CYH A 111 GLY A 114 LEU A 162	6UI  A 700 ( 4.9A) None 6UI  A 700 (-3.3A) 6UI  A 700 (-4.3A) 6UI  A 700 (-4.2A) 6UI  A 700 ( 4.2A) 6UI  A 700 (-4.2A)	1.15A	27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4wb7	DNAJ HOMOLOG SUBFAMILY B MEMBER 1,CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA (Homo sapiens)	7 / 12	LEU A 104 GLY A 105 ALA A 125 LYS A 127 VAL A 159 GLY A 181 LEU A 228	ATP  A 501 ( 4.3A) ATP  A 501 (-3.5A) ATP  A 501 (-3.4A) ATP  A 501 (-2.6A) None None ATP  A 501 (-4.5A)	0.94A	23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4wsq	AP2-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	8 / 12	LEU A  52 ALA A  72 VAL A 104 PHE A 128 CYH A 129 GLY A 132 LEU A 183 CYH A 193	KSA  A 405 ( 4.0A) KSA  A 405 (-3.2A) None KSA  A 405 (-4.8A) KSA  A 405 (-4.5A) KSA  A 405 (-3.5A) KSA  A 405 (-4.6A) KSA  A 405 (-3.4A)	0.56A	23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	7 / 12	GLY A 328 ALA A 348 LYS A 350 VAL A 379 PHE A 397 GLY A 401 LEU A 447	ATP  A 601 ( 4.1A) ATP  A 601 ( 3.7A) ATP  A 601 (-2.8A) None ATP  A 601 (-4.6A) None None	0.54A	25.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xcu	FIBROBLAST GROWTH FACTOR RECEPTOR 4 (Homo sapiens)	7 / 12	LEU A 473 GLY A 474 ALA A 501 LYS A 503 VAL A 550 GLY A 556 LEU A 619	40M  A1002 ( 4.6A) None 40M  A1002 ( 4.1A) 40M  A1002 (-4.0A) 40M  A1002 (-4.7A) 40M  A1002 ( 3.7A) 40M  A1002 (-4.5A)	0.59A	52.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xey	TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	8 / 12	LEU B 267 GLU B 277 ALA B 288 LYS B 290 VAL B 318 PHE B 336 GLY B 340 LEU B 389	1N1  B 601 (-3.7A) None 1N1  B 601 (-3.5A) 1N1  B 601 (-4.6A) 1N1  B 601 ( 4.3A) 1N1  B 601 ( 4.2A) 1N1  B 601 (-3.5A) 1N1  B 601 (-4.3A)	0.83A	32.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xuf	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	8 / 12	LEU A 616 GLY A 617 ALA A 642 LYS A 644 VAL A 675 CYH A 694 GLY A 697 LEU A 818	P30  A1001 (-4.0A) None P30  A1001 (-3.5A) P30  A1001 ( 4.0A) None P30  A1001 (-4.2A) P30  A1001 (-3.5A) P30  A1001 (-4.3A)	0.81A	52.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4xuf	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	8 / 12	LEU A 616 GLY A 617 ALA A 642 VAL A 675 CYH A 694 GLY A 697 LEU A 818 CYH A 828	P30  A1001 (-4.0A) None P30  A1001 (-3.5A) None P30  A1001 (-4.2A) P30  A1001 (-3.5A) P30  A1001 (-4.3A) P30  A1001 (-4.8A)	0.77A	52.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	4yhj	G PROTEIN-COUPLED RECEPTOR KINASE 4 (Homo sapiens)	7 / 12	LEU A 193 GLY A 194 ALA A 214 LYS A 216 VAL A 248 GLY A 270 LEU A 319	AN2  A 601 ( 4.2A) AN2  A 601 (-3.4A) AN2  A 601 (-3.6A) AN2  A 601 ( 3.9A) None None None	0.67A	21.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5a46	FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B (Homo sapiens)	7 / 12	LEU A 484 GLY A 485 ALA A 512 LYS A 514 VAL A 561 GLY A 567 LEU A 630	38O  A1769 (-3.2A) 38O  A1769 ( 4.7A) 38O  A1769 (-3.6A) 38O  A1769 ( 3.1A) 38O  A1769 (-4.3A) 38O  A1769 (-3.4A) 38O  A1769 (-4.6A)	0.33A	46.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5ci7	SERINE/THREONINE-PRO TEIN KINASE ULK1 (Homo sapiens)	7 / 12	GLY A  23 ALA A  44 LYS A  46 VAL A  76 CYH A  95 GLY A  98 LEU A 145	51W  A 401 (-3.3A) 51W  A 401 (-3.4A) GOL  A 404 ( 3.1A) None 51W  A 401 (-3.9A) 51W  A 401 (-3.7A) 51W  A 401 (-4.5A)	0.64A	29.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5e8y	TGF-BETA RECEPTOR TYPE-2 (Homo sapiens)	7 / 12	GLY A 251 ALA A 275 LYS A 277 PHE A 327 GLY A 331 LEU A 386 CYH A 396	STU  A 601 (-2.9A) STU  A 601 (-3.1A) STU  A 601 (-2.4A) STU  A 601 (-3.4A) STU  A 601 (-3.5A) STU  A 601 (-3.9A) STU  A 601 (-3.2A)	0.77A	29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5fm2	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET (Homo sapiens)	7 / 12	LEU A 730 GLY A 731 ALA A 756 LYS A 758 VAL A 804 GLY A 810 LEU A 881	PP1  A2012 (-4.6A) PP1  A2012 ( 3.9A) PP1  A2012 (-3.2A) PP1  A2012 (-4.1A) PP1  A2012 (-4.5A) PTR  A 809 (-2.4A) PP1  A2012 (-4.6A)	0.74A	41.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5grn	PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA (Homo sapiens)	10 / 12	LEU A 599 GLY A 600 GLU A 609 ALA A 625 LYS A 627 VAL A 658 CYH A 677 GLY A 680 LEU A 825 CYH A 835	748  A1001 (-3.8A) None None 748  A1001 (-3.7A) 748  A1001 (-4.0A) 748  A1001 ( 4.8A) 748  A1001 (-4.5A) 748  A1001 ( 4.0A) 748  A1001 (-4.3A) 748  A1001 (-4.5A)	0.68A	49.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5i3o	BMP-2-INDUCIBLE PROTEIN KINASE (Homo sapiens)	7 / 12	LEU A  57 ALA A  77 VAL A 109 CYH A 133 GLY A 136 LEU A 187 CYH A 197	IDV  A 401 (-3.8A) IDV  A 401 (-3.6A) None IDV  A 401 (-4.6A) IDV  A 401 (-3.4A) IDV  A 401 (-4.4A) IDV  A 401 (-3.6A)	0.79A	25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5j5t	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 (Homo sapiens)	7 / 12	GLY A  23 ALA A  43 LYS A  45 PHE A  92 CYH A  93 GLY A  96 LEU A 143	None 6G2  A 901 (-3.2A) 6G2  A 901 ( 3.9A) 6G2  A 901 (-4.1A) TPO  A 145 (-4.1A) 6G2  A 901 (-3.6A) 6G2  A 901 (-4.7A)	0.81A	22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5j5t	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 (Homo sapiens)	7 / 12	GLY A  23 ALA A  43 VAL A  74 PHE A  92 CYH A  93 GLY A  95 LEU A 143	None 6G2  A 901 (-3.2A) None 6G2  A 901 (-4.1A) TPO  A 145 (-4.1A) TPO  A 145 ( 4.7A) 6G2  A 901 (-4.7A)	1.04A	22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5j5t	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 (Homo sapiens)	7 / 12	GLY A  23 ALA A  43 VAL A  74 PHE A  92 CYH A  93 GLY A  96 LEU A 143	None 6G2  A 901 (-3.2A) None 6G2  A 901 (-4.1A) TPO  A 145 (-4.1A) 6G2  A 901 (-3.6A) 6G2  A 901 (-4.7A)	0.57A	22.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5j9z	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	6 / 12	LEU A 718 GLY A 719 ALA A 743 LYS A 745 GLY A 796 LEU A 844	6HJ  A1101 ( 4.6A) 6HJ  A1101 ( 4.2A) 6HJ  A1101 (-3.1A) 6HJ  A1101 (-4.2A) 6HJ  A1101 ( 4.5A) 6HJ  A1101 ( 4.8A)	0.61A	33.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	5jzn	SERINE/THREONINE-PRO TEIN KINASE DCLK1 (Homo sapiens)	7 / 12	GLY A 397 GLU A 406 ALA A 417 LYS A 419 VAL A 449 GLY A 471 LEU A 518	GUI  A 701 ( 3.8A) GUI  A 701 ( 4.7A) GUI  A 701 ( 3.9A) GUI  A 701 (-3.1A) None GUI  A 701 (-3.6A) GUI  A 701 (-4.4A)	0.55A	27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	1gng	GLYCOGEN SYNTHASE KINASE-3 BETA (Homo sapiens)	8 / 12	ILE A  62 GLY A  63 VAL A  70 ALA A  83 LYS A  85 GLU A  97 LEU A 132 TYR A 134	None	0.57A	11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	1py5	TGF-BETA RECEPTOR TYPE I (Homo sapiens)	8 / 12	GLU A 209 ILE A 211 GLY A 212 VAL A 219 ALA A 230 LYS A 232 GLU A 245 GLY A 286	None PY1  A 700 (-3.6A) None PY1  A 700 ( 4.7A) PY1  A 700 (-3.5A) PY1  A 700 (-3.9A) PY1  A 700 ( 4.9A) PY1  A 700 (-3.6A)	0.85A	15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	1py5	TGF-BETA RECEPTOR TYPE I (Homo sapiens)	8 / 12	ILE A 211 GLY A 212 VAL A 219 ALA A 230 LYS A 232 GLU A 245 TYR A 282 GLY A 286	PY1  A 700 (-3.6A) None PY1  A 700 ( 4.7A) PY1  A 700 (-3.5A) PY1  A 700 (-3.9A) PY1  A 700 ( 4.9A) PY1  A 700 (-4.6A) PY1  A 700 (-3.6A)	0.77A	15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	1rjb	FL CYTOKINE RECEPTOR (Homo sapiens)	7 / 12	GLY A 617 VAL A 624 ALA A 642 LYS A 644 GLU A 661 TYR A 693 GLY A 697	None	0.71A	12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	1t46	HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG (Homo sapiens)	7 / 12	GLY A 596 VAL A 603 ALA A 621 LYS A 623 GLU A 640 TYR A 672 GLY A 676	None STI  A   3 ( 4.6A) STI  A   3 (-3.5A) STI  A   3 (-3.7A) STI  A   3 (-3.6A) STI  A   3 ( 4.0A) STI  A   3 ( 3.8A)	0.81A	14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	1zlt	SERINE/THREONINE-PRO TEIN KINASE CHK1 (Homo sapiens)	9 / 12	GLY A  16 VAL A  23 ALA A  36 LYS A  38 GLU A  55 LEU A  84 TYR A  86 GLY A  90 GLU A  91	HYM  A 400 ( 3.8A) HYM  A 400 (-4.3A) HYM  A 400 (-3.5A) HYM  A 400 (-3.2A) None HYM  A 400 (-4.2A) HYM  A 400 (-4.7A) None HYM  A 400 ( 4.7A)	0.65A	11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	1zrz	PROTEIN KINASE C, IOTA (Homo sapiens)	7 / 12	ILE A 251 GLY A 252 VAL A 259 ALA A 272 LYS A 274 GLU A 293 TYR A 325	BI1  A1000 (-3.9A) BI1  A1000 (-3.6A) BI1  A1000 (-4.2A) BI1  A1000 (-3.4A) BI1  A1000 (-3.5A) BI1  A1000 ( 4.9A) BI1  A1000 (-4.2A)	0.56A	10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	1zws	DAP-KINASE RELATED PROTEIN 1 (Homo sapiens)	7 / 12	GLU A  17 GLY A  20 VAL A  27 ALA A  40 LYS A  42 GLU A  64 LEU A  93	None	0.64A	15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2a2a	DEATH-ASSOCIATED PROTEIN KINASE 2 (Homo sapiens)	7 / 12	GLU A  17 GLY A  20 VAL A  27 ALA A  40 LYS A  42 GLU A  64 LEU A  93	None None None GOL  A3001 (-3.5A) None None GOL  A3001 ( 4.5A)	0.65A	13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2a2a	DEATH-ASSOCIATED PROTEIN KINASE 2 (Homo sapiens)	7 / 12	GLY A  20 VAL A  27 ALA A  40 LYS A  42 LEU A  93 GLY A  99 ILE A 160	None None GOL  A3001 (-3.5A) None GOL  A3001 ( 4.5A) None GOL  A3001 ( 3.9A)	0.76A	13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2buj	SERINE/THREONINE-PRO TEIN KINASE 16 (Homo sapiens)	7 / 12	GLY A  27 VAL A  34 ALA A  47 LYS A  49 GLU A  65 LEU A  98 GLY A 104	STU  A1301 ( 3.8A) STU  A1301 (-4.8A) STU  A1301 (-3.6A) STU  A1301 ( 4.0A) None STU  A1301 ( 4.7A) STU  A1301 ( 4.0A)	0.76A	13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	7 / 12	GLY X  18 VAL X  25 ALA X  37 LYS X  39 GLU X  54 TYR X  84 GLY X  88	STU  X 902 ( 3.7A) STU  X 902 ( 4.8A) STU  X 902 (-3.1A) STU  X 902 (-3.1A) STU  X 902 ( 4.4A) STU  X 902 (-4.6A) STU  X 902 (-3.5A)	0.59A	15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2ogv	MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR PRECURSOR (Homo sapiens)	7 / 12	GLY A 589 VAL A 596 ALA A 614 LYS A 616 GLU A 633 TYR A 665 GLY A 669	None	0.75A	13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2r2p	EPHRIN TYPE-A RECEPTOR 5 (Homo sapiens)	8 / 12	ILE A 681 GLY A 682 VAL A 689 ALA A 705 LYS A 707 GLU A 724 TYR A 755 GLY A 759	None	0.86A	21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2v55	RHO-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	8 / 12	ILE A  82 GLY A  83 VAL A  90 ALA A 103 LYS A 105 GLU A 124 TYR A 155 GLY A 159	None ANP  A1480 ( 4.3A) None ANP  A1480 ( 3.9A) ANP  A1480 (-3.4A) None ANP  A1480 ( 4.9A) None	0.58A	11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2vuw	SERINE/THREONINE-PRO TEIN KINASE HASPIN (Homo sapiens)	7 / 12	ILE A 490 GLY A 491 VAL A 498 ALA A 509 LYS A 511 GLU A 535 ILE A 686	None 5ID  A1800 (-3.5A) 5ID  A1800 ( 4.5A) 5ID  A1800 (-3.4A) IOD  A1799 (-3.2A) None IOD  A1799 (-4.2A)	0.67A	12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2w4k	DEATH-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	7 / 12	GLU A  17 GLY A  20 VAL A  27 ALA A  40 LYS A  42 GLU A  64 LEU A  93	None ADP  A1303 (-3.4A) ADP  A1303 (-4.0A) ADP  A1303 (-3.5A) ADP  A1303 (-2.7A) ADP  A1303 ( 4.8A) ADP  A1303 ( 4.1A)	0.56A	13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2w4k	DEATH-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	7 / 12	GLY A  20 VAL A  27 ALA A  40 LYS A  42 LEU A  93 GLY A  99 ILE A 160	ADP  A1303 (-3.4A) ADP  A1303 (-4.0A) ADP  A1303 (-3.5A) ADP  A1303 (-2.7A) ADP  A1303 ( 4.1A) None ADP  A1303 ( 4.1A)	0.74A	13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2x4f	MYOSIN LIGHT CHAIN KINASE FAMILY MEMBER 4 (Homo sapiens)	7 / 12	GLU A 110 VAL A 120 ALA A 133 LYS A 135 TYR A 182 GLY A 186 ILE A 246	None 16X  A1374 (-4.8A) 16X  A1374 ( 3.8A) 16X  A1374 ( 4.3A) 16X  A1374 (-4.1A) 16X  A1374 (-4.0A) 16X  A1374 (-4.1A)	0.78A	11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2y7j	PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM (Homo sapiens)	7 / 12	ILE A  30 GLY A  31 VAL A  38 ALA A  51 LYS A  53 GLY A 113 GLU A 114	B49  A1294 (-3.9A) B49  A1294 (-4.0A) None B49  A1294 (-3.2A) None B49  A1294 (-3.6A) B49  A1294 ( 4.7A)	0.72A	11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2y7j	PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM (Homo sapiens)	7 / 12	ILE A  30 GLY A  31 VAL A  38 LYS A  53 GLU A  77 GLY A 113 GLU A 114	B49  A1294 (-3.9A) B49  A1294 (-4.0A) None None None B49  A1294 (-3.6A) B49  A1294 ( 4.7A)	0.80A	11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2z2w	WEE1-LIKE PROTEIN KINASE (Homo sapiens)	8 / 12	GLU A 303 ILE A 305 GLY A 306 VAL A 313 ALA A 326 LYS A 328 GLU A 346 TYR A 378	None 770  A 901 (-3.8A) 770  A 901 ( 4.6A) 770  A 901 ( 4.7A) 770  A 901 (-3.5A) 770  A 901 (-4.6A) 770  A 901 (-3.9A) 770  A 901 (-4.2A)	0.98A	16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2z2w	WEE1-LIKE PROTEIN KINASE (Homo sapiens)	7 / 12	ILE A 305 GLY A 306 VAL A 313 ALA A 326 GLU A 346 TYR A 378 GLY A 382	770  A 901 (-3.8A) 770  A 901 ( 4.6A) 770  A 901 ( 4.7A) 770  A 901 (-3.5A) 770  A 901 (-3.9A) 770  A 901 (-4.2A) 770  A 901 (-3.4A)	0.60A	16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3a62	RIBOSOMAL PROTEIN S6 KINASE BETA-1 (Homo sapiens)	8 / 12	GLY A  98 VAL A 105 ALA A 121 GLU A 143 LEU A 172 TYR A 174 GLY A 178 GLU A 179	STU  A 400 (-3.6A) STU  A 400 (-4.9A) STU  A 400 (-3.1A) STU  A 400 ( 4.3A) STU  A 400 ( 4.1A) STU  A 400 (-4.7A) STU  A 400 ( 4.4A) STU  A 400 (-3.6A)	0.92A	14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3b2t	FIBROBLAST GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	7 / 12	GLY A 488 VAL A 495 ALA A 515 LYS A 517 GLU A 534 TYR A 566 GLY A 570	M33  A1996 ( 3.8A) M33  A1996 ( 4.7A) M33  A1996 (-3.3A) M33  A1996 ( 4.5A) None M33  A1996 ( 4.7A) M33  A1996 ( 4.8A)	0.79A	12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3bqr	DEATH-ASSOCIATED PROTEIN KINASE 3 (Homo sapiens)	8 / 12	GLU A  17 GLY A  20 VAL A  27 ALA A  40 LYS A  42 GLU A  64 LEU A  93 GLU A 100	None 4RB  A 401 (-3.6A) 4RB  A 401 ( 4.4A) 4RB  A 401 (-3.3A) 4RB  A 401 ( 2.8A) GOL  A 503 (-2.8A) 4RB  A 401 ( 4.1A) 4RB  A 401 (-3.8A)	0.83A	13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3bqr	DEATH-ASSOCIATED PROTEIN KINASE 3 (Homo sapiens)	9 / 12	GLU A  17 GLY A  20 VAL A  27 ALA A  40 LYS A  42 LEU A  93 GLY A  99 GLU A 100 ILE A 160	None 4RB  A 401 (-3.6A) 4RB  A 401 ( 4.4A) 4RB  A 401 (-3.3A) 4RB  A 401 ( 2.8A) 4RB  A 401 ( 4.1A) None 4RB  A 401 (-3.8A) 4RB  A 401 (-3.5A)	0.80A	13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3c1x	HEPATOCYTE GROWTH FACTOR RECEPTOR (Homo sapiens)	7 / 12	ILE A1084 GLY A1085 VAL A1092 ALA A1108 LEU A1157 TYR A1159 GLY A1163	CKK  A1500 ( 4.4A) None CKK  A1500 ( 4.3A) CKK  A1500 (-3.2A) CKK  A1500 (-4.7A) CKK  A1500 (-4.5A) CKK  A1500 ( 4.5A)	0.66A	11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3d7u	TYROSINE-PROTEIN KINASE CSK (Homo sapiens)	8 / 12	ILE A 201 GLY A 202 VAL A 209 ALA A 220 LYS A 222 GLU A 236 TYR A 268 GLY A 272	None	0.82A	15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3dko	EPHRIN TYPE-A RECEPTOR 7 (Homo sapiens)	7 / 12	ILE A 639 GLY A 640 VAL A 647 ALA A 663 LYS A 665 GLU A 682 GLY A 717	IHZ  A1001 ( 4.8A) None IHZ  A1001 ( 4.4A) IHZ  A1001 (-3.3A) IHZ  A1001 ( 4.5A) IHZ  A1001 (-3.8A) IHZ  A1001 ( 3.9A)	0.77A	13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3fzp	PROTEIN TYROSINE KINASE 2 BETA (Homo sapiens)	7 / 12	GLY A 432 VAL A 439 ALA A 455 LYS A 457 GLU A 474 GLY A 508 GLU A 509	AGS  A 999 ( 4.2A) AGS  A 999 (-4.6A) AGS  A 999 (-3.6A) AGS  A 999 (-2.5A) AGS  A 999 (-3.6A) None AGS  A 999 (-3.8A)	0.76A	16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3g2f	BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-2 (Homo sapiens)	9 / 12	GLU A 207 ILE A 209 GLY A 210 VAL A 217 ALA A 228 LYS A 230 GLU A 243 TYR A 281 GLY A 285	None ADP  A 900 (-4.6A) ADP  A 900 (-3.4A) ADP  A 900 (-4.3A) ADP  A 900 (-3.4A) ADP  A 900 (-2.8A) ADP  A 900 ( 4.7A) None ADP  A 900 ( 4.2A)	0.83A	15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3hng	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	7 / 12	GLY A 834 VAL A 841 ALA A 859 LYS A 861 GLU A 878 TYR A 911 GLY A 915	None 8ST  A2001 ( 4.6A) 8ST  A2001 ( 3.8A) 8ST  A2001 (-4.0A) 8ST  A2001 (-3.7A) 8ST  A2001 (-4.9A) None	0.69A	12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3iec	SERINE/THREONINE-PRO TEIN KINASE MARK2 (Homo sapiens)	8 / 12	ILE A  59 GLY A  60 VAL A  67 ALA A  80 LYS A  82 TYR A 131 GLY A 135 GLU A 136	None	0.71A	14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3iec	SERINE/THREONINE-PRO TEIN KINASE MARK2 (Homo sapiens)	8 / 12	ILE A  59 GLY A  60 VAL A  67 LYS A  82 GLU A 100 TYR A 131 GLY A 135 GLU A 136	None	0.89A	14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3lm5	SERINE/THREONINE-PRO TEIN KINASE 17B (Homo sapiens)	8 / 12	GLY A  40 VAL A  47 ALA A  60 GLU A  80 LEU A 110 TYR A 112 GLY A 116 GLU A 117	None QUE  A   1 ( 4.6A) QUE  A   1 (-3.2A) QUE  A   1 (-3.1A) QUE  A   1 (-4.1A) QUE  A   1 (-4.9A) None None	0.74A	15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3mdy	BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-1B (Homo sapiens)	8 / 12	ILE A 210 GLY A 211 VAL A 218 ALA A 229 LYS A 231 GLU A 244 TYR A 281 GLY A 285	LDN  A   1 (-4.1A) LDN  A   1 ( 4.7A) LDN  A   1 ( 4.8A) LDN  A   1 (-3.6A) None None LDN  A   1 ( 4.8A) LDN  A   1 (-3.3A)	0.79A	16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3mvj	CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA (Homo sapiens)	8 / 12	GLY A  50 VAL A  57 ALA A  70 LYS A  72 GLU A  91 TYR A 122 GLY A 126 GLU A 127	XFE  A 351 ( 4.0A) XFE  A 351 ( 4.5A) XFE  A 351 (-3.2A) None None None None XFE  A 351 (-4.2A)	0.87A	18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3nuu	PKB-LIKE (Homo sapiens)	9 / 12	GLY A  89 VAL A  96 ALA A 109 LYS A 111 GLU A 130 LEU A 159 TYR A 161 GLY A 165 GLU A 166	JOZ  A 361 ( 4.3A) JOZ  A 361 ( 4.7A) JOZ  A 361 (-3.4A) SO4  A   5 (-2.8A) SO4  A   5 (-3.1A) JOZ  A 361 (-4.0A) None None None	0.75A	15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	7 / 12	GLY A 193 VAL A 200 ALA A 213 LYS A 215 GLU A 234 LEU A 263 GLY A 269	AMP  A 577 ( 3.7A) AMP  A 577 (-4.3A) AMP  A 577 (-3.4A) AMP  A 577 (-2.8A) None AMP  A 577 ( 4.7A) None	0.49A	9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3qfv	CDC42BPB PROTEIN (Homo sapiens)	7 / 12	ILE A  82 GLY A  83 VAL A  90 ALA A 103 LYS A 105 GLU A 124 TYR A 155	None NM7  A 416 (-3.0A) NM7  A 416 (-3.7A) NM7  A 416 ( 3.7A) EDO  A 417 (-3.5A) EDO  A 417 (-4.0A) NM7  A 416 (-4.4A)	0.68A	13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3tt0	BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	7 / 12	GLY A 485 VAL A 492 ALA A 512 LYS A 514 GLU A 531 TYR A 563 GLY A 567	07J  A   1 ( 4.9A) 07J  A   1 (-4.0A) 07J  A   1 (-3.5A) 07J  A   1 (-4.5A) 07J  A   1 (-3.8A) 07J  A   1 (-4.7A) 07J  A   1 (-3.7A)	0.67A	13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3zfx	EPHRIN TYPE-B RECEPTOR 1 (Homo sapiens)	8 / 12	GLU A 623 ILE A 625 GLY A 626 VAL A 633 ALA A 649 LYS A 651 GLU A 668 GLY A 703	None	0.83A	11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4af3	AURORA KINASE B (Homo sapiens)	8 / 12	GLY A  84 VAL A  91 ALA A 104 LYS A 106 LEU A 154 TYR A 156 GLY A 160 GLU A 161	VX6  A 500 ( 4.1A) VX6  A 500 ( 4.8A) VX6  A 500 (-3.4A) VX6  A 500 (-3.3A) None VX6  A 500 (-4.2A) VX6  A 500 (-3.3A) VX6  A 500 ( 4.6A)	0.97A	13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4aw5	EPHRIN TYPE-B RECEPTOR 4 (Homo sapiens)	8 / 12	GLU A  95 ILE A  97 GLY A  98 VAL A 105 ALA A 121 LYS A 123 GLU A 140 GLY A 175	None 30K  A1365 (-4.5A) 30K  A1365 ( 3.9A) 30K  A1365 ( 4.6A) 30K  A1365 (-3.2A) 30K  A1365 (-3.8A) None 30K  A1365 (-3.5A)	0.74A	14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4ckr	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 (Homo sapiens)	7 / 12	GLU A 614 GLY A 617 VAL A 624 ALA A 653 LYS A 655 GLU A 672 TYR A 703	None None DI1  A1000 (-4.8A) DI1  A1000 (-3.6A) DI1  A1000 (-3.9A) DI1  A1000 (-3.8A) DI1  A1000 (-4.0A)	0.71A	13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4e93	TYROSINE-PROTEIN KINASE FES/FPS (Homo sapiens)	7 / 12	ILE A 567 GLY A 568 VAL A 575 ALA A 588 LYS A 590 GLU A 607 GLY A 642	GUI  A 901 (-4.0A) GUI  A 901 ( 4.3A) GUI  A 901 (-4.5A) GUI  A 901 (-3.4A) GUI  A 901 (-2.8A) None GUI  A 901 (-3.5A)	0.80A	13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4f99	CELL DIVISION CYCLE 7-RELATED PROTEIN KINASE (Homo sapiens)	7 / 12	ILE A  64 GLY A  65 VAL A  72 ALA A  88 LYS A  90 GLU A 104 TYR A 136	None ADP  A 601 ( 3.8A) ADP  A 601 (-4.0A) ADP  A 601 (-3.5A) ADP  A 601 (-2.6A) None ADP  A 601 (-4.1A)	0.50A	13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4gv1	RAC-ALPHA SERINE/THREONINE-PRO TEIN KINASE (Homo sapiens)	8 / 12	GLY A 157 VAL A 164 ALA A 177 LYS A 179 GLU A 198 TYR A 229 GLY A 233 GLU A 234	GOL  A 505 ( 3.4A) 0XZ  A 501 (-4.5A) 0XZ  A 501 (-3.3A) GOL  A 503 ( 2.8A) GOL  A 503 (-3.6A) 0XZ  A 501 ( 4.9A) None GOL  A 505 ( 2.9A)	0.44A	11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4k33	FIBROBLAST GROWTH FACTOR RECEPTOR 3 (Homo sapiens)	7 / 12	GLY A 479 VAL A 486 ALA A 506 LYS A 508 GLU A 525 TYR A 557 GLY A 561	ACP  A 801 (-3.4A) ACP  A 801 (-4.2A) ACP  A 801 (-3.3A) ACP  A 801 (-2.7A) ACP  A 801 ( 4.8A) None ACP  A 801 ( 4.6A)	0.72A	13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4l52	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7, TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1 CHIMERA (Homo sapiens)	8 / 12	GLU A  40 GLY A  43 VAL A  50 ALA A  61 LYS A  63 GLU A  77 TYR A 106 GLY A 110	None 1UL  A 501 ( 4.1A) 1UL  A 501 ( 4.9A) 1UL  A 501 (-3.1A) None None 1UL  A 501 (-4.1A) 1UL  A 501 ( 3.7A)	1.02A	14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4lg4	SERINE/THREONINE-PRO TEIN KINASE 3 (Homo sapiens)	8 / 12	GLU A  31 GLY A  34 VAL A  41 ALA A  54 LYS A  56 GLU A  70 TYR A 101 GLY A 105	None None GOL  A 404 (-4.5A) GOL  A 404 ( 3.1A) GOL  A 403 ( 4.6A) None GOL  A 404 ( 4.9A) GOL  A 404 (-3.6A)	0.79A	18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4mk0	BETA-ADRENERGIC RECEPTOR KINASE 1 (Homo sapiens)	7 / 12	ILE A 197 GLY A 198 VAL A 205 ALA A 218 LYS A 220 GLU A 239 LEU A 271	29X  A 702 (-4.7A) 29X  A 702 ( 4.1A) 29X  A 702 (-4.7A) 29X  A 702 (-3.1A) 29X  A 702 (-3.6A) None 29X  A 702 ( 4.7A)	0.49A	8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4mk0	BETA-ADRENERGIC RECEPTOR KINASE 1 (Homo sapiens)	7 / 12	ILE A 197 VAL A 205 ALA A 218 LYS A 220 GLU A 239 LEU A 271 GLY A 277	29X  A 702 (-4.7A) 29X  A 702 (-4.7A) 29X  A 702 (-3.1A) 29X  A 702 (-3.6A) None 29X  A 702 ( 4.7A) None	0.81A	8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4o27	SERINE/THREONINE-PRO TEIN KINASE 24 (Homo sapiens)	8 / 12	GLU B  28 GLY B  31 VAL B  38 ALA B  51 LYS B  53 GLU B  70 TYR B 101 GLY B 105	None ADP  B 500 ( 3.8A) ADP  B 500 (-4.5A) ADP  B 500 (-3.3A) ADP  B 500 (-3.1A) None ADP  B 500 ( 4.7A) None	0.83A	16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4p2k	EPHRIN TYPE-A RECEPTOR 2 (Homo sapiens)	8 / 12	ILE A 619 GLY A 620 VAL A 627 ALA A 644 LYS A 646 GLU A 663 TYR A 694 GLY A 698	None	1.13A	15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4rt7	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	7 / 12	GLY A 617 VAL A 624 ALA A 642 LYS A 644 GLU A 661 TYR A 693 GLY A 697	None None P30  A1001 (-3.4A) P30  A1001 (-3.4A) P30  A1001 (-3.6A) P30  A1001 (-4.1A) P30  A1001 (-3.4A)	0.66A	10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4tnb	G PROTEIN-COUPLED RECEPTOR KINASE 5 (Homo sapiens)	7 / 12	GLY A 193 VAL A 200 ALA A 213 LYS A 215 GLU A 234 LEU A 263 GLY A 269	SGV  A 601 (-3.4A) SGV  A 601 ( 4.6A) SGV  A 601 (-3.3A) SGV  A 601 ( 4.2A) None SGV  A 601 (-4.5A) None	0.57A	10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4wb7	DNAJ HOMOLOG SUBFAMILY B MEMBER 1,CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA (Homo sapiens)	8 / 12	GLY A 105 VAL A 112 ALA A 125 LYS A 127 GLU A 146 TYR A 177 GLY A 181 GLU A 182	ATP  A 501 (-3.5A) ATP  A 501 (-4.0A) ATP  A 501 (-3.4A) ATP  A 501 (-2.6A) None None None ATP  A 501 (-3.5A)	0.83A	16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4xuf	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	7 / 12	GLY A 617 VAL A 624 ALA A 642 LYS A 644 GLU A 661 TYR A 693 GLY A 697	None P30  A1001 ( 4.8A) P30  A1001 (-3.5A) P30  A1001 ( 4.0A) P30  A1001 (-3.1A) P30  A1001 ( 4.4A) P30  A1001 (-3.5A)	0.76A	18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4yff	SERINE/THREONINE-PRO TEIN KINASE TNNI3K (Homo sapiens)	7 / 12	ILE A 469 GLY A 470 VAL A 477 ALA A 488 LYS A 490 GLU A 509 TYR A 541	4CV  A 801 (-4.3A) 4CV  A 801 ( 3.9A) None 4CV  A 801 (-3.5A) 4CV  A 801 (-3.9A) None 4CV  A 801 (-3.9A)	0.53A	13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4yhj	G PROTEIN-COUPLED RECEPTOR KINASE 4 (Homo sapiens)	7 / 12	GLY A 194 VAL A 201 ALA A 214 LYS A 216 GLU A 235 LEU A 264 GLY A 270	AN2  A 601 (-3.4A) AN2  A 601 (-4.0A) AN2  A 601 (-3.6A) AN2  A 601 ( 3.9A) None AN2  A 601 ( 4.8A) None	0.46A	11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	5a46	FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B (Homo sapiens)	7 / 12	GLY A 485 VAL A 492 ALA A 512 LYS A 514 GLU A 531 TYR A 563 GLY A 567	38O  A1769 ( 4.7A) 38O  A1769 (-4.5A) 38O  A1769 (-3.6A) 38O  A1769 ( 3.1A) EDO  A1766 (-4.1A) 38O  A1769 (-4.2A) 38O  A1769 (-3.4A)	0.51A	11.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	5ci7	SERINE/THREONINE-PRO TEIN KINASE ULK1 (Homo sapiens)	8 / 12	ILE A  22 GLY A  23 VAL A  30 ALA A  44 LYS A  46 GLU A  63 TYR A  94 GLY A  98	51W  A 401 (-3.9A) 51W  A 401 (-3.3A) 51W  A 401 ( 4.3A) 51W  A 401 (-3.4A) GOL  A 404 ( 3.1A) None 51W  A 401 ( 3.4A) 51W  A 401 (-3.7A)	0.59A	36.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	5es1	MAP/MICROTUBULE AFFINITY-REGULATING KINASE 4 (Homo sapiens)	7 / 12	ILE A  62 GLY A  63 VAL A  70 ALA A  83 LYS A  85 GLU A 103 TYR A 134	5RC  A4000 (-4.0A) 5RC  A4000 ( 4.3A) 5RC  A4000 (-4.6A) 5RC  A4000 (-3.6A) 5RC  A4000 (-2.8A) None 5RC  A4000 (-4.5A)	0.65A	14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	5es1	MAP/MICROTUBULE AFFINITY-REGULATING KINASE 4 (Homo sapiens)	8 / 12	ILE A  62 GLY A  63 VAL A  70 ALA A  83 LYS A  85 TYR A 134 GLY A 138 GLU A 139	5RC  A4000 (-4.0A) 5RC  A4000 ( 4.3A) 5RC  A4000 (-4.6A) 5RC  A4000 (-3.6A) 5RC  A4000 (-2.8A) 5RC  A4000 (-4.5A) 5RC  A4000 (-3.3A) None	0.72A	14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	5f1z	NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 (Homo sapiens)	7 / 12	GLY A 904 VAL A 911 ALA A 928 LYS A 930 GLU A 947 TYR A 980 GLY A 984	5U3  A1200 ( 3.7A) 5U3  A1200 ( 4.4A) 5U3  A1200 (-3.5A) None None 5U3  A1200 (-4.5A) 5U3  A1200 (-3.2A)	0.76A	15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	5fm2	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET (Homo sapiens)	7 / 12	GLY A 731 VAL A 738 ALA A 756 LYS A 758 GLU A 775 TYR A 806 GLY A 810	PP1  A2012 ( 3.9A) PP1  A2012 (-4.4A) PP1  A2012 (-3.2A) PP1  A2012 (-4.1A) PP1  A2012 (-3.5A) None PTR  A 809 (-2.4A)	0.64A	13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_1 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	5grn	PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA (Homo sapiens)	7 / 12	GLY A 600 VAL A 607 ALA A 625 LYS A 627 GLU A 644 TYR A 676 GLY A 680	None 748  A1001 ( 4.7A) 748  A1001 (-3.7A) 748  A1001 (-4.0A) 748  A1001 (-3.3A) 748  A1001 (-4.0A) 748  A1001 ( 4.0A)	0.73A	14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	1h4l	CELL DIVISION PROTEIN KINASE 5 (Homo sapiens)	4 / 5	LEU A  55 CYH A  83 LEU A 133 ASP A 144	None	0.82A	14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	1t6n	PROBABLE ATP-DEPENDENT RNA HELICASE (Homo sapiens)	4 / 5	LEU A 231 CYH A  87 CYH A  75 ASP A 196	None	1.22A	21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2ecl	RING-BOX PROTEIN 2 (Homo sapiens)	4 / 5	CYH A  48 CYH A  70 LEU A  69 ASP A  16	ZN  A 601 (-2.3A) ZN  A 601 (-2.2A) ZN  A 601 ( 4.6A) None	1.50A	17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2h0d	UBIQUITIN LIGASE PROTEIN RING2 (Homo sapiens)	4 / 5	LEU B 100 CYH B  51 LEU B  58 ASP B 103	None ZN  B 203 (-2.3A) None None	1.22A	25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	2ou2	HISTONE ACETYLTRANSFERASE HTATIP (Homo sapiens)	4 / 5	LEU A 185 CYH A 211 CYH A 231 LEU A 233	None ZN  A 490 (-2.3A) ZN  A 490 (-2.4A) None	1.37A	16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3gtu	GLUTATHIONE S-TRANSFERASE (Homo sapiens)	4 / 5	LEU B 114 CYH B 177 LEU B 178 ASP B 168	None	1.43A	17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3ldz	SIGNAL TRANSDUCING ADAPTER MOLECULE 1 (Homo sapiens)	4 / 5	CYH A  46 CYH A  72 LEU A  68 ASP A  12	None	1.36A	21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3lzb	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	4 / 5	LEU A 753 CYH A 751 LEU A 820 ASP A 831	ITI  A   1 (-3.8A) ITI  A   1 (-3.7A) ITI  A   1 (-4.6A) ITI  A   1 ( 4.6A)	1.46A	11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3mi9	CELL DIVISION PROTEIN KINASE 9 (Homo sapiens)	4 / 5	LEU A  70 CYH A 106 LEU A 156 ASP A 167	None	0.80A	12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	4 / 5	LEU A 889 CYH A 919 LEU A1035 ASP A1046	LEV  A1201 ( 4.4A) LEV  A1201 (-4.1A) LEV  A1201 (-4.8A) GOL  A1210 ( 3.4A)	0.43A	14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4bc6	SERINE/THREONINE-PRO TEIN KINASE 10 (Homo sapiens)	4 / 5	LEU A  85 CYH A 113 LEU A 164 ASP A 175	None XZN  A1317 (-3.7A) XZN  A1317 (-4.7A) XZN  A1317 (-3.2A)	0.42A	15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4jgv	NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 1 (Homo sapiens)	4 / 5	CYH A 505 CYH A 534 LEU A 365 ASP A 499	None None None GOL  A 606 (-3.8A)	1.20A	18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4k6j	WINGS APART-LIKE PROTEIN HOMOLOG (Homo sapiens)	4 / 5	LEU A 747 CYH A 675 LEU A 671 ASP A 709	None	1.41A	9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4oav	PROTEIN (RNASE L) (Homo sapiens)	4 / 5	LEU B 408 CYH B 437 LEU B 492 ASP B 503	None ACP  B 801 (-4.5A) ACP  B 801 (-4.5A) MG  B 803 (-1.8A)	0.86A	9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4z7g	SERINE/THREONINE-PRO TEIN KINASE/ENDORIBONUCLE ASE IRE1 (Homo sapiens)	4 / 5	LEU A 616 CYH A 645 LEU A 695 ASP A 711	None	0.88A	12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	4zzh	NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1 (Homo sapiens)	4 / 5	LEU A 250 CYH A 490 CYH A 501 LEU A 500	None	1.33A	15.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	5ci7	SERINE/THREONINE-PRO TEIN KINASE ULK1 (Homo sapiens)	4 / 5	LEU A  67 CYH A  95 LEU A 145 ASP A 165	None 51W  A 401 (-3.9A) 51W  A 401 (-4.5A) GOL  A 404 (-3.2A)	0.56A	36.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	5mr8	E3 UBIQUITIN-PROTEIN LIGASE TRIM33 (Homo sapiens)	4 / 5	LEU A1060 CYH A 966 LEU A 958 ASP A1022	None	1.36A	20.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	5tvt	MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE (Homo sapiens)	4 / 5	LEU A  61 CYH A  70 CYH A  89 ASP A 150	None 7LV  A 401 ( 3.7A) 7LV  A 401 (-4.3A) 7LV  A 401 (-4.2A)	0.72A	98.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	5tvt	MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE (Homo sapiens)	4 / 5	LEU A  61 CYH A  70 CYH A  89 LEU A 139	None 7LV  A 401 ( 3.7A) 7LV  A 401 (-4.3A) 7LV  A 401 (-4.9A)	0.19A	98.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	6dnh	CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4 (Homo sapiens)	4 / 5	LEU C  28 CYH C  55 CYH C  49 ASP C  80	None ZN  C 301 (-2.8A) ZN  C 301 (-2.4A) None	1.26A	17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	1h4l	CELL DIVISION PROTEIN KINASE 5 (Homo sapiens)	6 / 12	GLU A   8 ALA A  31 GLU A  51 VAL A  64 PHE A  82 LEU A 133	None	0.86A	25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	1snx	TYROSINE-PROTEIN KINASE ITK/TSK (Homo sapiens)	6 / 12	LEU A 379 ALA A 389 VAL A 419 PHE A 437 GLY A 441 LEU A 489	None	0.53A	23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	1snx	TYROSINE-PROTEIN KINASE ITK/TSK (Homo sapiens)	6 / 12	LEU A 379 MET A 410 VAL A 419 PHE A 437 GLY A 441 LEU A 489	None	0.76A	23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	1u59	TYROSINE-PROTEIN KINASE ZAP-70 (Homo sapiens)	6 / 12	ALA A 367 GLU A 386 MET A 390 VAL A 399 GLY A 420 LEU A 468	STU  A 100 (-3.2A) None None None STU  A 100 (-3.5A) STU  A 100 (-4.5A)	0.35A	22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	1zlt	SERINE/THREONINE-PRO TEIN KINASE CHK1 (Homo sapiens)	6 / 12	LEU A  25 ALA A  36 GLU A  55 VAL A  68 GLY A  90 LEU A 137	None HYM  A 400 (-3.5A) None HYM  A 400 (-4.8A) None HYM  A 400 (-4.5A)	0.49A	25.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	2buj	SERINE/THREONINE-PRO TEIN KINASE 16 (Homo sapiens)	7 / 12	LEU A  36 ALA A  47 GLU A  65 PHE A 100 GLY A 104 ASN A 108 LEU A 155	None STU  A1301 (-3.6A) None STU  A1301 (-4.5A) STU  A1301 ( 4.0A) None STU  A1301 ( 4.8A)	0.82A	31.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	2dq7	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FYN (Homo sapiens)	6 / 12	ALA X  37 GLU X  54 MET X  58 VAL X  67 GLY X  88 LEU X 137	STU  X 902 (-3.1A) STU  X 902 ( 4.4A) None None STU  X 902 (-3.5A) STU  X 902 (-4.4A)	0.53A	26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	2hak	SERINE/THREONINE-PRO TEIN KINASE MARK1 (Homo sapiens)	6 / 12	LEU A  69 ALA A  80 MET A 104 VAL A 113 GLY A 134 LEU A 182	None	1.01A	28.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	2hak	SERINE/THREONINE-PRO TEIN KINASE MARK1 (Homo sapiens)	6 / 12	LEU A  69 ALA A  80 MET A 104 VAL A 113 GLY A 135 LEU A 182	None	0.88A	28.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	2hk5	TYROSINE-PROTEIN KINASE HCK (Homo sapiens)	6 / 12	ALA A 271 MET A 292 VAL A 301 PHE A 318 GLY A 322 LEU A 371	1BM  A 499 (-3.6A) 1BM  A 499 ( 3.8A) None 1BM  A 499 (-4.1A) 1BM  A 499 (-3.5A) 1BM  A 499 (-4.4A)	0.72A	23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	7 / 12	ALA A 269 GLU A 286 MET A 290 VAL A 299 PHE A 317 GLY A 321 LEU A 370	GIN  A 600 (-3.1A) GIN  A 600 (-3.6A) GIN  A 600 (-3.2A) GIN  A 600 (-4.6A) GIN  A 600 (-4.3A) None GIN  A 600 (-4.7A)	0.49A	23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	2og8	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK (Homo sapiens)	7 / 12	GLU A 249 ALA A 271 GLU A 288 MET A 292 VAL A 301 GLY A 322 LEU A 371	None 1N8  A 501 ( 3.4A) 1N8  A 501 ( 3.6A) 1N8  A 501 ( 3.6A) None 1N8  A 501 ( 3.5A) 1N8  A 501 ( 4.3A)	0.76A	24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	2ogv	MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR PRECURSOR (Homo sapiens)	6 / 12	ALA A 614 GLU A 633 MET A 637 VAL A 647 GLY A 669 LEU A 785	None	0.69A	21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	2v55	RHO-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	6 / 12	LEU A  92 ALA A 103 GLU A 124 MET A 128 GLY A 158 LEU A 205	None ANP  A1480 ( 3.9A) None None None ANP  A1480 ( 4.7A)	1.13A	25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	2v55	RHO-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	7 / 12	LEU A  92 ALA A 103 GLU A 124 MET A 128 GLY A 159 ASN A 163 LEU A 205	None ANP  A1480 ( 3.9A) None None None None ANP  A1480 ( 4.7A)	1.05A	25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	2v55	RHO-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	6 / 12	LEU A  92 ALA A 103 GLU A 124 VAL A 137 GLY A 158 LEU A 205	None ANP  A1480 ( 3.9A) None ANP  A1480 (-4.7A) None ANP  A1480 ( 4.7A)	1.02A	25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	2v55	RHO-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	7 / 12	LEU A  92 ALA A 103 GLU A 124 VAL A 137 GLY A 159 ASN A 163 LEU A 205	None ANP  A1480 ( 3.9A) None ANP  A1480 (-4.7A) None None ANP  A1480 ( 4.7A)	1.00A	25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	2wtk	STE20-RELATED KINASE ADAPTER PROTEIN ALPHA (Homo sapiens)	6 / 12	LEU B  87 GLU B 118 VAL B 131 PHE B 149 GLY B 153 LEU B 202	None None None ANP  B 432 ( 4.9A) ANP  B 432 ( 4.2A) ANP  B 432 ( 4.7A)	0.88A	24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	2z7r	RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 (Homo sapiens)	6 / 12	LEU A  78 ALA A  92 VAL A 125 PHE A 143 GLY A 146 LEU A 194	None STU  A   1 (-3.3A) None STU  A   1 (-4.6A) None STU  A   1 (-4.6A)	0.92A	28.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	2z7r	RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 (Homo sapiens)	6 / 12	LEU A  78 ALA A  92 VAL A 125 PHE A 143 GLY A 147 LEU A 194	None STU  A   1 (-3.3A) None STU  A   1 (-4.6A) STU  A   1 ( 3.9A) STU  A   1 (-4.6A)	0.37A	28.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	3c0i	PERIPHERAL PLASMA MEMBRANE PROTEIN CASK (Homo sapiens)	6 / 12	GLU A  16 ALA A  39 VAL A  75 PHE A  93 GLY A  96 LEU A 148	None 3AM  A 338 (-3.3A) None 3AM  A 338 ( 4.6A) None 3AM  A 338 (-4.7A)	0.84A	27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	3c4f	BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	6 / 12	LEU A 494 ALA A 512 GLU A 531 MET A 535 GLY A 567 LEU A 630	None C4F  A   1 (-3.3A) None C4F  A   1 ( 3.7A) None C4F  A   1 (-4.6A)	0.61A	24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	3d7u	TYROSINE-PROTEIN KINASE CSK (Homo sapiens)	7 / 12	LEU A 211 ALA A 220 GLU A 236 MET A 240 VAL A 249 GLY A 272 LEU A 321	None	0.55A	23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	3iec	SERINE/THREONINE-PRO TEIN KINASE MARK2 (Homo sapiens)	6 / 12	LEU A  69 ALA A  80 MET A 104 VAL A 113 GLY A 135 LEU A 182	None	0.60A	27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	3iec	SERINE/THREONINE-PRO TEIN KINASE MARK2 (Homo sapiens)	6 / 12	LEU A  69 GLU A 100 MET A 104 VAL A 113 GLY A 135 LEU A 182	None	0.69A	27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	3mvj	CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA (Homo sapiens)	6 / 12	LEU A  59 ALA A  70 GLU A  91 VAL A 104 GLY A 126 LEU A 173	None XFE  A 351 (-3.2A) None None None XFE  A 351 (-4.6A)	0.64A	25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	3nuu	PKB-LIKE (Homo sapiens)	6 / 12	LEU A  98 ALA A 109 GLU A 130 MET A 134 GLY A 165 LEU A 212	None JOZ  A 361 (-3.4A) SO4  A   5 (-3.1A) None None None	0.38A	26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	3nuu	PKB-LIKE (Homo sapiens)	6 / 12	LEU A  98 ALA A 109 GLU A 130 VAL A 143 GLY A 165 LEU A 212	None JOZ  A 361 (-3.4A) SO4  A   5 (-3.1A) None None None	0.61A	26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	3sxs	CYTOPLASMIC TYROSINE-PROTEIN KINASE BMX (Homo sapiens)	6 / 12	LEU A 433 ALA A 443 MET A 464 VAL A 473 GLY A 495 LEU A 543	None PP2  A   1 (-3.2A) PP2  A   1 ( 4.3A) None PP2  A   1 ( 4.2A) PP2  A   1 (-4.6A)	0.59A	25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	3tt0	BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	6 / 12	LEU A 494 ALA A 512 GLU A 531 MET A 535 GLY A 567 LEU A 630	None 07J  A   1 (-3.5A) 07J  A   1 (-3.8A) 07J  A   1 (-3.8A) 07J  A   1 (-3.7A) 07J  A   1 ( 4.4A)	0.53A	24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	3txo	PROTEIN KINASE C ETA TYPE (Homo sapiens)	6 / 12	LEU A 371 ALA A 382 GLU A 403 PHE A 435 GLY A 439 LEU A 486	None 07U  A   1 (-3.3A) 07U  A   1 ( 4.8A) None None 07U  A   1 (-4.3A)	0.58A	25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	3v5q	NT-3 GROWTH FACTOR RECEPTOR (Homo sapiens)	6 / 12	LEU A 554 ALA A 570 GLU A 588 VAL A 601 GLY A 623 LEU A 686	None 0F4  A 902 (-3.2A) 0F4  A 902 (-3.6A) None 0F4  A 902 (-3.4A) 0F4  A 902 (-4.5A)	0.71A	22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	3vid	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	6 / 12	ALA A 866 GLU A 885 VAL A 899 PHE A 918 GLY A 922 LEU A1035	4TT  A2001 (-3.5A) None None 4TT  A2001 (-4.5A) 4TT  A2001 (-3.7A) 4TT  A2001 (-4.8A)	0.44A	23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	6 / 12	ALA A 866 GLU A 885 VAL A 899 PHE A 918 GLY A 922 LEU A1035	LEV  A1201 (-3.5A) LEV  A1201 (-3.7A) None LEV  A1201 (-4.7A) LEV  A1201 (-3.6A) LEV  A1201 (-4.8A)	0.61A	24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4agd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	6 / 12	ALA A 866 GLU A 885 VAL A 899 PHE A 918 GLY A 922 LEU A1035	B49  A2000 (-3.5A) None B49  A2000 ( 4.6A) B49  A2000 (-4.4A) B49  A2000 ( 3.7A) B49  A2000 (-4.5A)	0.57A	25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4bc6	SERINE/THREONINE-PRO TEIN KINASE 10 (Homo sapiens)	6 / 12	ALA A  63 GLU A  81 VAL A  94 PHE A 112 GLY A 116 LEU A 164	XZN  A1317 (-3.5A) XZN  A1317 (-3.9A) XZN  A1317 (-4.4A) XZN  A1317 (-4.5A) XZN  A1317 ( 3.7A) XZN  A1317 (-4.7A)	0.61A	27.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4ckr	EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 (Homo sapiens)	7 / 12	GLU A 614 LEU A 626 ALA A 653 GLU A 672 MET A 676 GLY A 707 LEU A 773	None None DI1  A1000 (-3.6A) DI1  A1000 (-3.8A) DI1  A1000 (-3.6A) None DI1  A1000 (-4.5A)	0.82A	22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4crs	SERINE/THREONINE-PRO TEIN KINASE N2 (Homo sapiens)	6 / 12	LEU A 673 ALA A 684 GLU A 705 VAL A 721 GLY A 743 LEU A 789	None AGS  A1985 (-3.5A) None None None AGS  A1985 (-4.8A)	0.39A	25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4fie	SERINE/THREONINE-PRO TEIN KINASE PAK 4 (Homo sapiens)	6 / 12	ALA A 348 GLU A 366 VAL A 379 PHE A 397 GLY A 401 LEU A 447	ANP  A1001 (-3.6A) ANP  A1001 (-3.6A) None ANP  A1001 ( 4.6A) None ANP  A1001 (-4.7A)	0.72A	23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4fie	SERINE/THREONINE-PRO TEIN KINASE PAK 4 (Homo sapiens)	6 / 12	ALA A 348 MET A 370 VAL A 379 PHE A 397 GLY A 401 LEU A 447	ANP  A1001 (-3.6A) None None ANP  A1001 ( 4.6A) None ANP  A1001 (-4.7A)	0.76A	23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4hvi	TYROSINE-PROTEIN KINASE JAK3 (Homo sapiens)	6 / 12	LEU A 838 ALA A 853 GLU A 871 VAL A 884 GLY A 908 LEU A 956	None 19S  A1201 (-3.3A) None None 19S  A1201 ( 3.8A) 19S  A1201 (-4.5A)	0.54A	25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4ks8	SERINE/THREONINE-PRO TEIN KINASE PAK 6 (Homo sapiens)	6 / 12	LEU A 423 ALA A 434 GLU A 452 PHE A 483 GLY A 487 LEU A 533	None B49  A 701 (-3.2A) None B49  A 701 (-4.3A) B49  A 701 ( 3.7A) B49  A 701 (-4.5A)	0.73A	27.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4ks8	SERINE/THREONINE-PRO TEIN KINASE PAK 6 (Homo sapiens)	6 / 12	LEU A 423 ALA A 434 VAL A 465 PHE A 483 GLY A 487 LEU A 533	None B49  A 701 (-3.2A) None B49  A 701 (-4.3A) B49  A 701 ( 3.7A) B49  A 701 (-4.5A)	0.54A	27.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4l52	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7, TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1 CHIMERA (Homo sapiens)	6 / 12	GLU A  40 ALA A  61 GLU A  77 VAL A  90 GLY A 110 ASN A 114	None 1UL  A 501 (-3.1A) None None 1UL  A 501 ( 3.7A) 1UL  A 501 ( 4.4A)	0.90A	25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4l52	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7, TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1 CHIMERA (Homo sapiens)	6 / 12	GLU A  40 ALA A  61 GLU A  77 VAL A  90 GLY A 110 LEU A 163	None 1UL  A 501 (-3.1A) None None 1UL  A 501 ( 3.7A) 1UL  A 501 (-4.3A)	0.72A	25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4lg4	SERINE/THREONINE-PRO TEIN KINASE 3 (Homo sapiens)	6 / 12	ALA A  54 GLU A  70 MET A  74 VAL A  83 GLY A 105 LEU A 153	GOL  A 404 ( 3.1A) None None GOL  A 403 (-4.1A) GOL  A 404 (-3.6A) GOL  A 403 ( 4.4A)	1.01A	29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4lg4	SERINE/THREONINE-PRO TEIN KINASE 3 (Homo sapiens)	6 / 12	GLU A  31 ALA A  54 GLU A  70 MET A  74 VAL A  83 GLY A 105	None GOL  A 404 ( 3.1A) None None GOL  A 403 (-4.1A) GOL  A 404 (-3.6A)	1.11A	29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4lg4	SERINE/THREONINE-PRO TEIN KINASE 3 (Homo sapiens)	6 / 12	LEU A  33 ALA A  54 GLU A  70 MET A  74 VAL A  83 LEU A 153	GOL  A 404 ( 3.6A) GOL  A 404 ( 3.1A) None None GOL  A 403 (-4.1A) GOL  A 403 ( 4.4A)	1.42A	29.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4o38	CYCLIN-G-ASSOCIATED KINASE (Homo sapiens)	6 / 12	ALA A  47 ALA A  67 GLU A  85 VAL A  99 GLY A 128 LEU A 180	None SIN  A 401 ( 3.7A) None None SIN  A 401 (-3.5A) SIN  A 401 ( 4.5A)	0.85A	35.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4o38	CYCLIN-G-ASSOCIATED KINASE (Homo sapiens)	7 / 12	ALA A  67 GLU A  85 MET A  89 VAL A  99 GLY A 128 GLN A 129 LEU A 180	SIN  A 401 ( 3.7A) None None None SIN  A 401 (-3.5A) None SIN  A 401 ( 4.5A)	0.79A	35.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4wb7	DNAJ HOMOLOG SUBFAMILY B MEMBER 1,CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA (Homo sapiens)	6 / 12	LEU A 114 ALA A 125 GLU A 146 VAL A 159 GLY A 181 LEU A 228	None ATP  A 501 (-3.4A) None None None ATP  A 501 (-4.5A)	0.58A	23.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4wsq	AP2-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	10 / 12	GLU A  50 ALA A  53 LEU A  62 ALA A  72 GLU A  90 MET A  94 VAL A 104 PHE A 128 GLY A 132 LEU A 183	None KSA  A 405 (-3.3A) None KSA  A 405 (-3.2A) None None None KSA  A 405 (-4.8A) KSA  A 405 (-3.5A) KSA  A 405 (-4.6A)	0.76A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4wsq	AP2-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	8 / 12	GLU A  50 ALA A  53 LEU A  62 ALA A  72 MET A  94 VAL A 104 PHE A 128 GLY A 131	None KSA  A 405 (-3.3A) None KSA  A 405 (-3.2A) None None KSA  A 405 (-4.8A) None	0.88A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4wsq	AP2-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	9 / 12	GLU A  50 LEU A  62 ALA A  72 MET A  94 VAL A 104 PHE A 128 GLY A 132 GLN A 133 LEU A 183	None None KSA  A 405 (-3.2A) None None KSA  A 405 (-4.8A) KSA  A 405 (-3.5A) KSA  A 405 (-3.2A) KSA  A 405 (-4.6A)	0.67A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	6 / 12	ALA A 348 MET A 370 VAL A 379 PHE A 397 GLY A 400 LEU A 447	ATP  A 601 ( 3.7A) None None ATP  A 601 (-4.6A) None None	1.23A	25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4xbr	PROTEIN FAM212A,SERINE/THREO NINE-PROTEIN KINASE PAK 4 (Homo sapiens)	6 / 12	ALA A 348 MET A 370 VAL A 379 PHE A 397 GLY A 401 LEU A 447	ATP  A 601 ( 3.7A) None None ATP  A 601 (-4.6A) None None	0.76A	25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	4xey	TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	6 / 12	ALA B 288 MET B 309 VAL B 318 PHE B 336 GLY B 340 LEU B 389	1N1  B 601 (-3.5A) 1N1  B 601 (-3.7A) 1N1  B 601 ( 4.3A) 1N1  B 601 ( 4.2A) 1N1  B 601 (-3.5A) 1N1  B 601 (-4.3A)	0.58A	24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	5a46	FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B (Homo sapiens)	6 / 12	LEU A 494 ALA A 512 GLU A 531 MET A 535 GLY A 567 LEU A 630	None 38O  A1769 (-3.6A) EDO  A1766 (-4.1A) EDO  A1766 (-3.5A) 38O  A1769 (-3.4A) 38O  A1769 (-4.6A)	0.55A	23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	5d7a	TRAF2 AND NCK-INTERACTING PROTEIN KINASE (Homo sapiens)	6 / 12	GLU A  29 ALA A  52 GLU A  69 PHE A 107 GLY A 111 LEU A 160	GLU  A  29 ( 0.6A) ALA  A  52 (-0.0A) GLU  A  69 ( 0.6A) PHE  A 107 ( 1.3A) GLY  A 111 (-0.0A) LEU  A 160 (-0.6A)	0.65A	26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	5es1	MAP/MICROTUBULE AFFINITY-REGULATING KINASE 4 (Homo sapiens)	6 / 12	LEU A  72 ALA A  83 GLU A 103 VAL A 116 GLY A 138 LEU A 185	None 5RC  A4000 (-3.6A) None None 5RC  A4000 (-3.3A) None	0.62A	28.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	5grn	PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA (Homo sapiens)	6 / 12	ALA A 625 GLU A 644 MET A 648 VAL A 658 GLY A 680 LEU A 825	748  A1001 (-3.7A) 748  A1001 (-3.3A) 748  A1001 (-3.4A) 748  A1001 ( 4.8A) 748  A1001 ( 4.0A) 748  A1001 (-4.3A)	0.45A	24.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	5i3o	BMP-2-INDUCIBLE PROTEIN KINASE (Homo sapiens)	8 / 12	GLU A  55 ALA A  58 LEU A  67 ALA A  77 GLU A  95 MET A  99 VAL A 109 LEU A 187	None IDV  A 401 (-3.3A) None IDV  A 401 (-3.6A) None None None IDV  A 401 (-4.4A)	0.93A	77.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	5i3o	BMP-2-INDUCIBLE PROTEIN KINASE (Homo sapiens)	9 / 12	GLU A  55 LEU A  67 ALA A  77 GLU A  95 MET A  99 VAL A 109 GLY A 136 GLN A 137 LEU A 187	None None IDV  A 401 (-3.6A) None None None IDV  A 401 (-3.4A) IDV  A 401 (-3.7A) IDV  A 401 (-4.4A)	0.85A	77.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	5i3o	BMP-2-INDUCIBLE PROTEIN KINASE (Homo sapiens)	8 / 12	GLU A  55 LEU A  67 GLU A  95 VAL A 109 GLY A 136 GLN A 137 ASN A 140 LEU A 187	None None None None IDV  A 401 (-3.4A) IDV  A 401 (-3.7A) IDV  A 401 ( 4.5A) IDV  A 401 (-4.4A)	0.99A	77.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	5j5t	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3 (Homo sapiens)	7 / 12	ALA A  43 GLU A  61 MET A  65 VAL A  74 PHE A  92 GLY A  96 LEU A 143	6G2  A 901 (-3.2A) None None None 6G2  A 901 (-4.1A) 6G2  A 901 (-3.6A) 6G2  A 901 (-4.7A)	0.50A	26.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	5kbr	SERINE/THREONINE-PRO TEIN KINASE PAK 1 (Homo sapiens)	6 / 12	ALA A 297 GLU A 315 MET A 319 VAL A 328 GLY A 350 LEU A 396	IPW  A 601 (-3.5A) IPW  A 601 (-3.9A) IPW  A 601 (-4.1A) None IPW  A 601 ( 3.8A) IPW  A 601 (-4.5A)	0.61A	26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	5u7q	RHO-ASSOCIATED PROTEIN KINASE 2 (Homo sapiens)	6 / 12	LEU A 108 ALA A 119 MET A 144 GLY A 175 ASN A 179 LEU A 221	None	1.06A	22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	5u7q	RHO-ASSOCIATED PROTEIN KINASE 2 (Homo sapiens)	6 / 12	LEU A 108 ALA A 119 VAL A 153 GLY A 175 ASN A 179 LEU A 221	None	0.86A	22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	5vef	SERINE/THREONINE-PRO TEIN KINASE PAK 4 (Homo sapiens)	6 / 12	ALA A 348 GLU A 366 VAL A 379 PHE A 397 GLY A 401 LEU A 447	M77  A 601 ( 3.5A) None None M77  A 601 (-4.1A) M77  A 601 ( 4.8A) M77  A 601 (-4.6A)	0.60A	28.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	5vil	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 (Homo sapiens)	5 / 12	ALA A 707 GLU A 725 VAL A 738 GLY A 760 LEU A 810	9E1  A1001 (-3.5A) None 9E1  A1001 (-4.1A) 9E1  A1001 (-3.4A) 9E1  A1001 (-4.5A)	0.32A	15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	5vo1	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 12 (Homo sapiens)	6 / 12	LEU A 141 ALA A 150 PHE A 192 GLY A 196 GLN A 197 LEU A 243	None 9FS  A 501 (-3.4A) 9FS  A 501 (-4.3A) 9FS  A 501 (-3.6A) 9FS  A 501 ( 4.0A) 9FS  A 501 (-4.7A)	0.69A	25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	6c0t	CGMP-DEPENDENT PROTEIN KINASE 1 (Homo sapiens)	6 / 12	LEU A 376 ALA A 388 GLU A 409 MET A 413 VAL A 422 GLY A 444	None EE4  A 701 (-3.3A) DMS  A 702 ( 4.2A) None None None	0.71A	13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	6c7y	TYROSINE-PROTEIN KINASE JAK1 (Homo sapiens)	7 / 12	LEU A 891 ALA A 906 GLU A 925 VAL A 938 PHE A 958 GLY A 962 LEU A1010	None ADP  A1201 (-3.4A) None None None ADP  A1201 ( 4.1A) ADP  A1201 (-4.5A)	0.65A	14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	6c9d	SERINE/THREONINE-PRO TEIN KINASE MARK1,SERINE/THREONI NE-PROTEIN KINASE MARK1 (Homo sapiens)	7 / 12	LEU A  76 ALA A  87 GLU A 107 MET A 111 VAL A 120 GLY A 142 LEU A 189	None	0.65A	14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 12	LEU A 181 ALA A 192 GLU A 236 VAL A 249 GLY A 273 LEU A 319	None F6J  A 501 (-3.4A) F6J  A 501 ( 4.7A) None F6J  A 501 ( 3.7A) F6J  A 501 (-4.5A)	0.65A	10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	1rjb	FL CYTOKINE RECEPTOR (Homo sapiens)	4 / 5	LEU A 616 VAL A 624 CYH A 694 CYH A 828	None	0.58A	23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	1t46	HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG (Homo sapiens)	4 / 5	LEU A 595 VAL A 603 CYH A 673 CYH A 809	STI  A   3 ( 3.8A) STI  A   3 ( 4.6A) STI  A   3 (-4.5A) STI  A   3 (-4.5A)	0.52A	21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	2wtk	SERINE/THREONINE-PRO TEIN KINASE 11 (Homo sapiens)	4 / 5	LEU C  55 VAL C  63 MET C 129 CYH C 132	ANP  C   2 ( 4.4A) ANP  C   2 (-4.2A) None ANP  C   2 (-4.5A)	0.94A	27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	3fme	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 6 (Homo sapiens)	4 / 5	LEU A  59 VAL A  67 MET A 129 CYH A 196	STU  A   1 (-3.8A) None STU  A   1 ( 3.8A) STU  A   1 ( 3.7A)	0.62A	24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	3hng	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 (Homo sapiens)	4 / 5	LEU A 833 VAL A 841 CYH A 912 CYH A1039	8ST  A2001 ( 4.7A) 8ST  A2001 ( 4.6A) 8ST  A2001 (-3.8A) 8ST  A2001 (-4.2A)	0.42A	24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	3i4u	ATP-DEPENDENT RNA HELICASE DHX8 (Homo sapiens)	4 / 5	LEU A1006 VAL A1009 MET A 992 CYH A1001	None	1.37A	22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	3un9	NLR FAMILY MEMBER X1 (Homo sapiens)	4 / 5	LEU A 701 VAL A 730 CYH A 713 CYH A 735	None	1.40A	22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	3vid	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	4 / 5	LEU A 840 VAL A 848 CYH A 919 CYH A1045	4TT  A2001 ( 4.0A) 4TT  A2001 ( 4.5A) 4TT  A2001 (-4.3A) None	0.49A	23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	3wzd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	4 / 5	LEU A 840 VAL A 848 CYH A 919 CYH A1045	LEV  A1201 ( 3.8A) LEV  A1201 ( 4.9A) LEV  A1201 (-4.1A) GOL  A1210 ( 3.3A)	0.38A	24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	4agd	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (Homo sapiens)	4 / 5	LEU A 840 VAL A 848 CYH A 919 CYH A1045	B49  A2000 (-3.7A) None B49  A2000 (-4.2A) B49  A2000 ( 4.1A)	0.59A	25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	4da1	PROTEIN PHOSPHATASE 1K, MITOCHONDRIAL (Homo sapiens)	4 / 5	LEU A 160 VAL A 192 CYH A 145 CYH A 138	None None BME  A 502 (-2.0A) None	1.28A	21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	4eut	SERINE/THREONINE-PRO TEIN KINASE TBK1 (Homo sapiens)	4 / 5	LEU A  15 VAL A  23 MET A  86 CYH A  89	BX7  A 401 (-3.7A) BX7  A 401 (-4.4A) BX7  A 401 (-4.5A) BX7  A 401 (-4.1A)	0.83A	24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	4euu	SERINE/THREONINE-PRO TEIN KINASE TBK1 (Homo sapiens)	4 / 5	LEU A  15 VAL A  23 MET A  86 CYH A  89	BX7  A 401 (-3.9A) BX7  A 401 ( 4.6A) BX7  A 401 (-3.7A) BX7  A 401 (-4.1A)	0.64A	25.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	4idt	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 14 (Homo sapiens)	4 / 5	LEU A 406 VAL A 414 MET A 469 CYH A 533	T28  A 701 (-3.8A) T28  A 701 (-4.7A) T28  A 701 (-2.6A) T28  A 701 (-3.7A)	0.85A	23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	4lg4	SERINE/THREONINE-PRO TEIN KINASE 3 (Homo sapiens)	4 / 5	LEU A  33 VAL A  41 MET A  99 CYH A 102	GOL  A 404 ( 3.6A) GOL  A 404 (-4.5A) GOL  A 403 (-2.7A) GOL  A 403 (-4.0A)	0.52A	29.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	4o38	CYCLIN-G-ASSOCIATED KINASE (Homo sapiens)	4 / 5	LEU A  46 VAL A  54 CYH A 126 CYH A 190	SIN  A 401 ( 3.9A) None SIN  A 401 (-4.3A) None	0.52A	35.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	4rt7	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	4 / 5	LEU A 616 VAL A 624 CYH A 694 CYH A 828	P30  A1001 (-3.8A) None None P30  A1001 (-4.1A)	0.44A	22.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	4wsq	AP2-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	5 / 5	LEU A  52 VAL A  60 MET A 126 CYH A 129 CYH A 193	KSA  A 405 ( 4.0A) KSA  A 405 ( 4.9A) KSA  A 405 ( 3.7A) KSA  A 405 (-4.5A) KSA  A 405 (-3.4A)	0.57A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	4xuf	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3 (Homo sapiens)	4 / 5	LEU A 616 VAL A 624 CYH A 694 CYH A 828	P30  A1001 (-4.0A) P30  A1001 ( 4.8A) P30  A1001 (-4.2A) P30  A1001 (-4.8A)	0.58A	24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	5grn	PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA (Homo sapiens)	4 / 5	LEU A 599 VAL A 607 CYH A 677 CYH A 835	748  A1001 (-3.8A) 748  A1001 ( 4.7A) 748  A1001 (-4.5A) 748  A1001 (-4.5A)	0.56A	24.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	5i3o	BMP-2-INDUCIBLE PROTEIN KINASE (Homo sapiens)	5 / 5	LEU A  57 VAL A  65 MET A 130 CYH A 133 CYH A 197	IDV  A 401 (-3.8A) IDV  A 401 (-4.6A) IDV  A 401 (-3.4A) IDV  A 401 (-4.6A) IDV  A 401 (-3.6A)	0.68A	77.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	6ao5	SERINE/THREONINE-PRO TEIN KINASE 3 (Homo sapiens)	4 / 5	LEU A  33 VAL A  41 MET A  99 CYH A 102	ANP  A 501 ( 3.8A) ANP  A 501 (-4.4A) ANP  A 501 (-2.5A) ANP  A 501 (-4.2A)	0.72A	26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_2 (AP2-ASSOCIATED PROTEIN KINASE 1)	6c0t	CGMP-DEPENDENT PROTEIN KINASE 1 (Homo sapiens)	4 / 5	LEU A 366 VAL A 374 MET A 438 CYH A 441	EE4  A 701 ( 4.6A) EE4  A 701 (-4.4A) EE4  A 701 ( 3.8A) EE4  A 701 (-4.6A)	0.62A	13.45