POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	1d1t	ALCOHOL DEHYDROGENASE CLASS IV SIGMA CHAIN (Homo sapiens)	5 / 11	GLY A 204 ALA A 182 GLY A 179 VAL A 197 CYH A 211	None	1.19A	24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	1gq4	EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN-50 (Homo sapiens)	5 / 11	ALA A  51 GLY A  52 VAL A  42 VAL A  90 CYH A  15	None None CL  A1102 ( 4.9A) None None	1.34A	12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	1wl4	ACETYL-COENZYME A ACETYLTRANSFERASE 2 (Homo sapiens)	5 / 11	GLY A  58 ALA A 260 GLY A 117 VAL A  70 MET A 119	None	1.42A	22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	2m0u	NA(+)/H(+) EXCHANGE REGULATORY COFACTOR NHE-RF1 (Homo sapiens)	5 / 11	ALA A  51 GLY A  52 VAL A  42 VAL A  90 CYH A  15	None	1.26A	16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	2vsp	PDZ DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 11	ALA A 415 GLY A 416 VAL A 406 VAL A 454 CYH A 379	None	1.32A	17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3dwd	ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 (Homo sapiens)	5 / 11	GLY A  38 GLY A  79 VAL A  33 MET A  75 VAL A  13	None	1.37A	16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3juc	AIG2-LIKE DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 11	ASP A  22 ALA A  24 GLY A  23 VAL A  19 MET A  74	None	1.16A	19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3o47	ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1, ADP-RIBOSYLATION FACTOR 1 (Homo sapiens)	5 / 11	GLY A  38 GLY A  79 VAL A  33 MET A  75 VAL A  13	None	1.40A	20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3s5n	4-HYDROXY-2-OXOGLUTA RATE ALDOLASE, MITOCHONDRIAL (Homo sapiens)	5 / 11	GLY A  37 ALA A 221 GLY A 238 VAL A 250 CYH A 240	None	1.07A	22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3tju	GRANZYME H (Homo sapiens)	5 / 11	GLY A  46 ALA A  57 GLY A 198 VAL A  33 HIS A  59	None	1.44A	21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3un9	NLR FAMILY MEMBER X1 (Homo sapiens)	5 / 11	GLY A 823 ASP A 821 ALA A 847 GLY A 820 VAL A 842	None	1.11A	21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4ad9	BETA-LACTAMASE-LIKE PROTEIN 2 (Homo sapiens)	5 / 11	GLY A  84 ASP A  81 GLY A  48 VAL A  75 HIS A 199	None ZN  A1000 (-2.8A) None None ZN  A1000 (-3.3A)	1.13A	23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4m9p	FILAMIN-A (Homo sapiens)	5 / 11	GLY A 583 ASP A 596 ALA A 595 GLY A 585 VAL A 645	None	1.05A	22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4mgx	FILAMIN-C (Homo sapiens)	5 / 11	GLY A 578 ASP A 591 ALA A 590 GLY A 580 VAL A 640	None	1.05A	24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_C_UEGC300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	1d1t	ALCOHOL DEHYDROGENASE CLASS IV SIGMA CHAIN (Homo sapiens)	5 / 10	GLY A 204 ALA A 182 GLY A 179 VAL A 197 CYH A 211	None	1.21A	24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_C_UEGC300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	1gq4	EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN-50 (Homo sapiens)	5 / 10	ALA A  51 GLY A  52 VAL A  42 VAL A  90 CYH A  15	None None CL  A1102 ( 4.9A) None None	1.29A	12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_C_UEGC300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	1wl4	ACETYL-COENZYME A ACETYLTRANSFERASE 2 (Homo sapiens)	5 / 10	GLY A  58 ALA A 260 GLY A 117 VAL A  70 MET A 119	None	1.45A	22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_C_UEGC300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	2m0u	NA(+)/H(+) EXCHANGE REGULATORY COFACTOR NHE-RF1 (Homo sapiens)	5 / 10	ALA A  51 GLY A  52 VAL A  42 VAL A  90 CYH A  15	None	1.21A	16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_C_UEGC300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	2vsp	PDZ DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 10	ALA A 415 GLY A 416 VAL A 406 VAL A 454 CYH A 379	None	1.29A	17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_C_UEGC300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3dwd	ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 (Homo sapiens)	5 / 10	GLY A  38 GLY A  79 VAL A  33 MET A  75 VAL A  13	None	1.42A	16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_C_UEGC300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3juc	AIG2-LIKE DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 10	ASP A  22 ALA A  24 GLY A  23 VAL A  19 MET A  74	None	1.12A	19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_C_UEGC300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3o47	ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1, ADP-RIBOSYLATION FACTOR 1 (Homo sapiens)	5 / 10	GLY A  38 GLY A  79 VAL A  33 MET A  75 VAL A  13	None	1.45A	20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_C_UEGC300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3tju	GRANZYME H (Homo sapiens)	5 / 10	GLY A  46 ALA A  57 GLY A 198 VAL A  33 HIS A  59	None	1.39A	21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_C_UEGC300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3un9	NLR FAMILY MEMBER X1 (Homo sapiens)	5 / 10	GLY A 823 ASP A 821 ALA A 847 GLY A 820 VAL A 842	None	1.11A	21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_C_UEGC300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4ad9	BETA-LACTAMASE-LIKE PROTEIN 2 (Homo sapiens)	5 / 10	GLY A  84 ASP A  81 GLY A  48 VAL A  75 HIS A 199	None ZN  A1000 (-2.8A) None None ZN  A1000 (-3.3A)	1.13A	23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_C_UEGC300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4m9p	FILAMIN-A (Homo sapiens)	5 / 10	GLY A 583 ASP A 596 ALA A 595 GLY A 585 VAL A 645	None	1.13A	22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_C_UEGC300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4mgx	FILAMIN-C (Homo sapiens)	5 / 10	GLY A 578 ASP A 591 ALA A 590 GLY A 580 VAL A 640	None	1.12A	24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	1d1t	ALCOHOL DEHYDROGENASE CLASS IV SIGMA CHAIN (Homo sapiens)	5 / 10	GLY A 204 ALA A 182 GLY A 179 VAL A 197 CYH A 211	None	1.17A	24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	1gq4	EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN-50 (Homo sapiens)	5 / 10	ALA A  51 GLY A  52 VAL A  42 VAL A  90 CYH A  15	None None CL  A1102 ( 4.9A) None None	1.32A	12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	1wl4	ACETYL-COENZYME A ACETYLTRANSFERASE 2 (Homo sapiens)	5 / 10	GLY A  58 ALA A 260 GLY A 117 VAL A  70 MET A 119	None	1.46A	22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	2m0u	NA(+)/H(+) EXCHANGE REGULATORY COFACTOR NHE-RF1 (Homo sapiens)	5 / 10	ALA A  51 GLY A  52 VAL A  42 VAL A  90 CYH A  15	None	1.24A	16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	2vsp	PDZ DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 10	ALA A 415 GLY A 416 VAL A 406 VAL A 454 CYH A 379	None	1.30A	17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3dwd	ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 (Homo sapiens)	5 / 10	GLY A  38 GLY A  79 VAL A  33 MET A  75 VAL A  13	None	1.38A	16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3juc	AIG2-LIKE DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 10	ASP A  22 ALA A  24 GLY A  23 VAL A  19 MET A  74	None	1.15A	19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3o47	ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1, ADP-RIBOSYLATION FACTOR 1 (Homo sapiens)	5 / 10	GLY A  38 GLY A  79 VAL A  33 MET A  75 VAL A  13	None	1.41A	20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3s5n	4-HYDROXY-2-OXOGLUTA RATE ALDOLASE, MITOCHONDRIAL (Homo sapiens)	5 / 10	GLY A  37 ALA A 221 GLY A 238 VAL A 250 CYH A 240	None	1.07A	22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3un9	NLR FAMILY MEMBER X1 (Homo sapiens)	5 / 10	GLY A 823 ASP A 821 ALA A 847 GLY A 820 VAL A 842	None	1.14A	21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4ad9	BETA-LACTAMASE-LIKE PROTEIN 2 (Homo sapiens)	5 / 10	GLY A  84 ASP A  81 GLY A  48 VAL A  75 HIS A 199	None ZN  A1000 (-2.8A) None None ZN  A1000 (-3.3A)	1.14A	23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4m9p	FILAMIN-A (Homo sapiens)	5 / 10	GLY A 583 ASP A 596 ALA A 595 GLY A 585 VAL A 645	None	1.12A	22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4mgx	FILAMIN-C (Homo sapiens)	5 / 10	GLY A 578 ASP A 591 ALA A 590 GLY A 580 VAL A 640	None	1.11A	24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	1d1t	ALCOHOL DEHYDROGENASE CLASS IV SIGMA CHAIN (Homo sapiens)	5 / 10	GLY A 204 ALA A 182 GLY A 179 VAL A 197 CYH A 211	None	1.16A	24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	1gq4	EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN-50 (Homo sapiens)	5 / 10	ALA A  51 GLY A  52 VAL A  42 VAL A  90 CYH A  15	None None CL  A1102 ( 4.9A) None None	1.22A	12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	1gz4	NAD-DEPENDENT MALIC ENZYME (Homo sapiens)	5 / 10	GLY A 182 ALA A 189 VAL A 111 VAL A 468 CYH A 190	None	1.40A	19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	1t2f	L-LACTATE DEHYDROGENASE B CHAIN (Homo sapiens)	5 / 10	GLY A  27 ALA A  34 GLY A  32 VAL A 136 CYH A  35	NAD  A 401 ( 4.5A) None None NAD  A 401 (-4.0A) None	1.34A	22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	1wl4	ACETYL-COENZYME A ACETYLTRANSFERASE 2 (Homo sapiens)	5 / 10	GLY A  58 ALA A 260 GLY A 117 VAL A  70 MET A 119	None	1.41A	22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	1yb5	QUINONE OXIDOREDUCTASE (Homo sapiens)	5 / 10	GLY A 159 ALA A 165 GLY A 162 VAL A 189 CYH A 166	CL  A 816 ( 3.1A) None CL  A 816 (-3.3A) None None	1.41A	21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	2fzw	ALCOHOL DEHYDROGENASE CLASS III CHI CHAIN (Homo sapiens)	5 / 10	GLY A 203 ALA A 181 GLY A 178 VAL A 196 CYH A 210	None	1.26A	24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	2m0u	NA(+)/H(+) EXCHANGE REGULATORY COFACTOR NHE-RF1 (Homo sapiens)	5 / 10	ALA A  51 GLY A  52 VAL A  42 VAL A  90 CYH A  15	None	1.22A	16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	2vsp	PDZ DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 10	ALA A 415 GLY A 416 VAL A 406 VAL A 454 CYH A 379	None	1.19A	17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	2y7b	ACTIN-BINDING PROTEIN ANILLIN (Homo sapiens)	5 / 10	GLY A 998 ALA A1001 GLY A1000 VAL A1073 HIS A1003	None	1.27A	13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3dwd	ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 (Homo sapiens)	5 / 10	GLY A  38 GLY A  79 VAL A  33 MET A  75 VAL A  13	None	1.45A	16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3ihp	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 5 (Homo sapiens)	5 / 10	GLY A 137 ASP A 134 ALA A 132 GLY A 135 VAL A 147	None	1.28A	16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3juc	AIG2-LIKE DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 10	ASP A  22 ALA A  24 GLY A  23 VAL A  19 MET A  74	None	1.15A	19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	3un9	NLR FAMILY MEMBER X1 (Homo sapiens)	5 / 10	GLY A 823 ASP A 821 ALA A 847 GLY A 820 VAL A 842	None	1.16A	21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4ad9	BETA-LACTAMASE-LIKE PROTEIN 2 (Homo sapiens)	5 / 10	GLY A  84 ASP A  81 GLY A  48 VAL A  75 HIS A 199	None ZN  A1000 (-2.8A) None None ZN  A1000 (-3.3A)	1.15A	23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4m9p	FILAMIN-A (Homo sapiens)	5 / 10	GLY A 583 ASP A 596 ALA A 595 GLY A 585 VAL A 645	None	1.15A	22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4mgx	FILAMIN-C (Homo sapiens)	5 / 10	GLY A 578 ASP A 591 ALA A 590 GLY A 580 VAL A 640	None	1.14A	24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB3_A_UEGA202_1 (YFIR)	1zcm	CALPAIN 1, LARGE [CATALYTIC] SUBUNIT (Homo sapiens)	4 / 4	LEU A 175 ILE A 170 PRO A  88 LEU A  92	None	0.84A	19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB3_A_UEGA202_1 (YFIR)	2pkg	SERINE/THREONINE-PRO TEIN PHOSPHATASE 2A 65 KDA REGULATORY SUBUNIT A ALPHA ISOFORM (Homo sapiens)	4 / 4	LEU A 551 ILE A 547 PRO A 523 LEU A 526	None	0.99A	15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB3_A_UEGA202_1 (YFIR)	3v8d	CHOLESTEROL 7-ALPHA-MONOOXYGENAS E (Homo sapiens)	4 / 4	LEU A  71 ILE A  39 PRO A  52 LEU A  56	None	0.88A	16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB3_A_UEGA202_1 (YFIR)	4lac	PP2A SCAFFOLD SUBUNIT A, TRUNCATED, AN INTERNAL DELETION OF PP2A A (Homo sapiens)	4 / 4	LEU A 551 ILE A 547 PRO A 523 LEU A 526	None	1.18A	21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB3_A_UEGA202_1 (YFIR)	4nj8	ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 3 (Homo sapiens)	4 / 4	LEU A  15 ILE A  18 PRO A  55 LEU A  45	None	1.00A	21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB3_A_UEGA202_1 (YFIR)	5exr	DNA POLYMERASE ALPHA CATALYTIC SUBUNIT (Homo sapiens)	4 / 4	LEU C 537 ILE C 633 PRO C 763 LEU C 766	None	1.21A	9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB3_A_UEGA202_1 (YFIR)	5ggg	PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLU COSAMINYLTRANSFERASE 1 (Homo sapiens)	4 / 4	LEU A 406 ILE A 422 PRO A 493 LEU A 530	None	1.20A	15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB3_A_UEGA202_1 (YFIR)	5iud	DNA POLYMERASE ALPHA CATALYTIC SUBUNIT (Homo sapiens)	4 / 4	LEU A 537 ILE A 633 PRO A 763 LEU A 766	None	1.14A	10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB3_A_UEGA202_1 (YFIR)	5tbk	IMPORTIN SUBUNIT ALPHA-3 (Homo sapiens)	4 / 4	LEU A 205 ILE A 208 PRO A 245 LEU A 247	None	1.19A	14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB3_A_UEGA202_1 (YFIR)	5vi6	HISTONE DEACETYLASE 8 (Homo sapiens)	4 / 4	LEU A 366 ILE A 362 PRO A 230 LEU A 200	None	1.04A	20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB3_A_UEGA202_1 (YFIR)	5wbg	CYTOCHROME P450 2B6 (Homo sapiens)	4 / 4	LEU A 431 ILE A 435 PRO A 428 LEU A 392	None	1.23A	22.15