POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IA0_B_TXLB502_1 (TUBULIN BETA CHAIN)	2ed7	NETRIN RECEPTOR DCC (Homo sapiens)	5 / 12	VAL A  24 ASP A  23 LEU A  81 SER A 103 PRO A 105	None	1.32A	15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IA0_B_TXLB502_1 (TUBULIN BETA CHAIN)	2m7s	SERINE/ARGININE-RICH SPLICING FACTOR 1 (Homo sapiens)	5 / 12	VAL A  47 LEU A  70 THR A  73 PRO A  24 GLY A  22	None	1.29A	12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IA0_B_TXLB502_1 (TUBULIN BETA CHAIN)	2wd9	ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL (Homo sapiens)	5 / 12	VAL A 167 ASP A 168 LEU A  97 ARG A 178 GLY A 190	None	1.42A	22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IA0_B_TXLB502_1 (TUBULIN BETA CHAIN)	2y1h	PUTATIVE DEOXYRIBONUCLEASE TATDN3 (Homo sapiens)	5 / 12	LEU A 130 HIS A 147 SER A 190 THR A 155 GLY A 174	None ZN  A1273 ( 3.1A) None None None	1.29A	20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IA0_B_TXLB502_1 (TUBULIN BETA CHAIN)	3hb0	EYES ABSENT HOMOLOG 2 (DROSOPHILA) (Homo sapiens)	5 / 12	VAL A 336 ASP A 339 ASP A 329 PHE A 355 GLY A 373	None	1.23A	21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IA0_B_TXLB502_1 (TUBULIN BETA CHAIN)	3i2n	WD REPEAT-CONTAINING PROTEIN 92 (Homo sapiens)	5 / 12	VAL A 170 ASP A 118 ASP A 166 ARG A 266 GLY A  71	None	1.39A	22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IA0_B_TXLB502_1 (TUBULIN BETA CHAIN)	3j2s	COAGULATION FACTOR VIII LIGHT CHAIN (Homo sapiens)	5 / 12	LEU B1752 HIS B1755 ARG B1764 ARG B1705 GLY B1760	None	1.39A	20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IA0_B_TXLB502_1 (TUBULIN BETA CHAIN)	3thc	BETA-GALACTOSIDASE (Homo sapiens)	5 / 12	VAL A 158 LEU A 233 PHE A 207 THR A 219 PRO A 122	None	1.40A	19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IA0_B_TXLB502_1 (TUBULIN BETA CHAIN)	4eku	PROTEIN-TYROSINE KINASE 2-BETA (Homo sapiens)	5 / 12	ASP A 346 LEU A 144 THR A 150 ARG A 353 GLY A  91	None	1.34A	21.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1IA0_B_TXLB502_1 (TUBULIN BETA CHAIN)	5n5n	TUBULIN BETA CHAIN (Homo sapiens)	5 / 12	LEU B 217 ASP B 226 PHE B 272 ARG B 320 PRO B 360	None	1.01A	97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1IA0_B_TXLB502_1 (TUBULIN BETA CHAIN)	5n5n	TUBULIN BETA CHAIN (Homo sapiens)	5 / 12	LEU B 217 PHE B 272 THR B 276 ARG B 320 PRO B 360	None	0.97A	97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1IA0_B_TXLB502_1 (TUBULIN BETA CHAIN)	5n5n	TUBULIN BETA CHAIN (Homo sapiens)	5 / 12	LEU B 217 THR B 276 ARG B 320 PRO B 360 GLY B 370	None	0.81A	97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1IA0_B_TXLB502_1 (TUBULIN BETA CHAIN)	5n5n	TUBULIN BETA CHAIN (Homo sapiens)	6 / 12	VAL B  23 HIS B 229 SER B 236 ARG B 320 PRO B 360 GLY B 370	None	1.14A	97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1IA0_B_TXLB502_1 (TUBULIN BETA CHAIN)	5n5n	TUBULIN BETA CHAIN (Homo sapiens)	6 / 12	VAL B  23 LEU B 217 HIS B 229 ARG B 320 PRO B 360 GLY B 370	None	1.00A	97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1IA0_B_TXLB502_1 (TUBULIN BETA CHAIN)	5n5n	TUBULIN BETA CHAIN (Homo sapiens)	6 / 12	VAL B  23 LEU B 217 HIS B 229 PHE B 272 ARG B 320 PRO B 360	None	1.01A	97.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TUB_B_TXLB501_1 (TUBULIN)	2ed7	NETRIN RECEPTOR DCC (Homo sapiens)	5 / 12	VAL A  24 ASP A  23 LEU A  81 SER A 103 PRO A 105	None	1.33A	16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TUB_B_TXLB501_1 (TUBULIN)	2m7s	SERINE/ARGININE-RICH SPLICING FACTOR 1 (Homo sapiens)	5 / 12	VAL A  47 LEU A  70 THR A  73 PRO A  24 GLY A  22	None	1.30A	12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TUB_B_TXLB501_1 (TUBULIN)	2wd9	ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL (Homo sapiens)	5 / 12	VAL A 167 ASP A 168 LEU A  97 ARG A 178 GLY A 190	None	1.42A	22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TUB_B_TXLB501_1 (TUBULIN)	2y1h	PUTATIVE DEOXYRIBONUCLEASE TATDN3 (Homo sapiens)	5 / 12	LEU A 130 HIS A 147 SER A 190 THR A 155 GLY A 174	None ZN  A1273 ( 3.1A) None None None	1.29A	20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TUB_B_TXLB501_1 (TUBULIN)	3hb0	EYES ABSENT HOMOLOG 2 (DROSOPHILA) (Homo sapiens)	5 / 12	VAL A 336 ASP A 339 ASP A 329 PHE A 355 GLY A 373	None	1.23A	21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TUB_B_TXLB501_1 (TUBULIN)	3i2n	WD REPEAT-CONTAINING PROTEIN 92 (Homo sapiens)	5 / 12	VAL A 170 ASP A 118 ASP A 166 ARG A 266 GLY A  71	None	1.39A	23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TUB_B_TXLB501_1 (TUBULIN)	3j2s	COAGULATION FACTOR VIII LIGHT CHAIN (Homo sapiens)	5 / 12	LEU B1752 HIS B1755 ARG B1764 ARG B1705 GLY B1760	None	1.39A	20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TUB_B_TXLB501_1 (TUBULIN)	3thc	BETA-GALACTOSIDASE (Homo sapiens)	5 / 12	VAL A 158 LEU A 233 PHE A 207 THR A 219 PRO A 122	None	1.40A	19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TUB_B_TXLB501_1 (TUBULIN)	4eku	PROTEIN-TYROSINE KINASE 2-BETA (Homo sapiens)	5 / 12	ASP A 346 LEU A 144 THR A 150 ARG A 353 GLY A  91	None	1.34A	21.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1TUB_B_TXLB501_1 (TUBULIN)	5n5n	TUBULIN BETA CHAIN (Homo sapiens)	5 / 12	LEU B 217 ASP B 226 PHE B 272 ARG B 320 PRO B 360	None	1.02A	97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1TUB_B_TXLB501_1 (TUBULIN)	5n5n	TUBULIN BETA CHAIN (Homo sapiens)	5 / 12	LEU B 217 PHE B 272 THR B 276 ARG B 320 PRO B 360	None	0.97A	97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1TUB_B_TXLB501_1 (TUBULIN)	5n5n	TUBULIN BETA CHAIN (Homo sapiens)	5 / 12	LEU B 217 THR B 276 ARG B 320 PRO B 360 GLY B 370	None	0.81A	97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1TUB_B_TXLB501_1 (TUBULIN)	5n5n	TUBULIN BETA CHAIN (Homo sapiens)	6 / 12	VAL B  23 HIS B 229 SER B 236 ARG B 320 PRO B 360 GLY B 370	None	1.14A	97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1TUB_B_TXLB501_1 (TUBULIN)	5n5n	TUBULIN BETA CHAIN (Homo sapiens)	6 / 12	VAL B  23 LEU B 217 HIS B 229 ARG B 320 PRO B 360 GLY B 370	None	1.00A	97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1TUB_B_TXLB501_1 (TUBULIN)	5n5n	TUBULIN BETA CHAIN (Homo sapiens)	6 / 12	VAL B  23 LEU B 217 HIS B 229 PHE B 272 ARG B 320 PRO B 360	None	1.01A	97.89