POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		1h4l CELL DIVISION
PROTEIN KINASE 5
(Homo
sapiens)		5 / 12PHE A  80
LEU A  66
ALA A 148
SER A  47
TYR A  15
None
1.44A21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		1hjv CHITINASE-3 LIKE
PROTEIN 1
(Homo
sapiens)		5 / 12TYR A  27
VAL A  25
ALA A 138
SER A  95
SER A 175
NAG  A  -1 (-3.8A)
None
NAG  A  -1 ( 3.9A)
None
None
1.42A19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		1skx ORPHAN NUCLEAR
RECEPTOR PXR
(Homo
sapiens)		5 / 12PHE A 369
LEU A 342
ALA A 157
SER A 262
TYR A 263
None
1.38A19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		1wou THIOREDOXIN -RELATED
PROTEIN, 14 KDA
(Homo
sapiens)		5 / 12PHE A 120
LEU A  57
GLU A   6
ARG A  54
ALA A  49
None
1.13A19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		2aex COPROPORPHYRINOGEN
III OXIDASE,
MITOCHONDRIAL
(Homo
sapiens)		5 / 12PHE A 339
PHE A 353
HIS A 297
SER A 364
TYR A 261
None
0.94A19.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		3apu ALPHA-1-ACID
GLYCOPROTEIN 2
(Homo
sapiens)		6 / 12TYR A  37
GLU A  64
ARG A  90
HIS A  97
SER A  30
TYR A  27
None
PG4  A 190 (-4.1A)
PG4  A 190 (-4.3A)
None
None
PG4  A 190 ( 3.8A)
1.37A100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		3apu ALPHA-1-ACID
GLYCOPROTEIN 2
(Homo
sapiens)		6 / 12TYR A  37
PHE A  49
LEU A  62
HIS A  97
ALA A  99
SER A 114
None
PG4  A 190 ( 4.1A)
None
None
PG4  A 190 ( 4.2A)
None
1.48A100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		3apu ALPHA-1-ACID
GLYCOPROTEIN 2
(Homo
sapiens)		12 / 12TYR A  37
VAL A  41
PHE A  49
PHE A  51
LEU A  62
GLU A  64
ARG A  90
HIS A  97
ALA A  99
SER A 114
SER A 125
TYR A 127
None
PG4  A 190 (-4.9A)
PG4  A 190 ( 4.1A)
None
None
PG4  A 190 (-4.1A)
PG4  A 190 (-4.3A)
None
PG4  A 190 ( 4.2A)
None
PG4  A 190 ( 3.7A)
None
0.61A100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens)		8 / 12PHE A  49
PHE A  51
LEU A  62
GLU A  64
ARG A  90
ALA A  99
SER A 125
TYR A 127
JIM  A 193 (-3.8A)
None
None
None
JIM  A 193 (-4.3A)
JIM  A 193 ( 4.0A)
None
None
0.80A86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens)		5 / 12PHE A  51
HIS A  97
ALA A  99
SER A 125
TYR A 127
None
None
JIM  A 193 ( 4.0A)
None
None
0.76A86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens)		5 / 12PHE A  51
LEU A  62
ARG A  90
ALA A  99
TYR A 110
None
None
JIM  A 193 (-4.3A)
JIM  A 193 ( 4.0A)
None
1.46A86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens)		5 / 12PHE A  51
LEU A  79
HIS A  97
SER A 125
TYR A 127
None
1.34A86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens)		8 / 12VAL A  41
PHE A  49
PHE A  51
LEU A  62
ARG A  90
ALA A  99
SER A 125
TYR A 127
None
JIM  A 193 (-3.8A)
None
None
JIM  A 193 (-4.3A)
JIM  A 193 ( 4.0A)
None
None
0.70A86.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		4goj PROTEIN UNC-119
HOMOLOG A
(Homo
sapiens)		5 / 12PHE C 159
PHE C 149
HIS C 192
SER C 218
TYR C 220
None
1.45A18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		4um8 INTEGRIN ALPHA-V
INTEGRIN BETA-6
(Homo
sapiens)		5 / 12PHE A 427
GLU B 291
ARG A 339
ALA A 343
SER A 279
None
None
SO4  A1597 ( 4.8A)
None
None
1.44A15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		1h4l CELL DIVISION
PROTEIN KINASE 5
(Homo
sapiens)		5 / 12PHE A  80
LEU A  66
ALA A 148
SER A  47
TYR A  15
None
1.43A21.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		3apu ALPHA-1-ACID
GLYCOPROTEIN 2
(Homo
sapiens)		11 / 12PHE A  32
TYR A  37
VAL A  41
PHE A  49
PHE A  51
LEU A  62
GLU A  64
ARG A  90
HIS A  97
ALA A  99
SER A 125
None
None
PG4  A 190 (-4.9A)
PG4  A 190 ( 4.1A)
None
None
PG4  A 190 (-4.1A)
PG4  A 190 (-4.3A)
None
PG4  A 190 ( 4.2A)
PG4  A 190 ( 3.7A)
0.71A100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		3apu ALPHA-1-ACID
GLYCOPROTEIN 2
(Homo
sapiens)		11 / 12PHE A  32
TYR A  37
VAL A  41
PHE A  49
PHE A  51
LEU A  62
GLU A  64
HIS A  97
ALA A  99
SER A 125
TYR A 127
None
None
PG4  A 190 (-4.9A)
PG4  A 190 ( 4.1A)
None
None
PG4  A 190 (-4.1A)
None
PG4  A 190 ( 4.2A)
PG4  A 190 ( 3.7A)
None
0.49A100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		3apu ALPHA-1-ACID
GLYCOPROTEIN 2
(Homo
sapiens)		8 / 12PHE A  32
TYR A  37
VAL A  41
PHE A  51
LEU A  79
HIS A  97
SER A 125
TYR A 127
None
None
PG4  A 190 (-4.9A)
None
None
None
PG4  A 190 ( 3.7A)
None
1.41A100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		3h8m EPHRIN TYPE-A
RECEPTOR 7
(Homo
sapiens)		5 / 12PHE A 944
TYR A 949
VAL A 928
LEU A 989
ARG A 957
PHE  A 944 ( 1.4A)
TYR  A 949 ( 1.3A)
VAL  A 928 ( 0.6A)
LEU  A 989 ( 0.5A)
ARG  A 957 ( 0.6A)
1.49A17.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens)		7 / 12PHE A  32
PHE A  49
PHE A  51
HIS A  97
ALA A  99
SER A 125
TYR A 127
None
JIM  A 193 (-3.8A)
None
None
JIM  A 193 ( 4.0A)
None
None
0.89A86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens)		6 / 12PHE A  32
PHE A  51
LEU A  79
HIS A  97
SER A 125
TYR A 127
None
1.29A86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens)		9 / 12PHE A  32
VAL A  41
PHE A  49
PHE A  51
LEU A  62
GLU A  64
ALA A  99
SER A 125
TYR A 127
None
None
JIM  A 193 (-3.8A)
None
None
None
JIM  A 193 ( 4.0A)
None
None
0.68A86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens)		8 / 12PHE A  32
VAL A  41
PHE A  49
PHE A  51
LEU A  62
GLU A  64
ARG A  90
ALA A  99
None
None
JIM  A 193 (-3.8A)
None
None
None
JIM  A 193 (-4.3A)
JIM  A 193 ( 4.0A)
0.91A86.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		3kq0 ALPHA-1-ACID
GLYCOPROTEIN 1
(Homo
sapiens)		5 / 12PHE A  51
LEU A  62
ARG A  90
ALA A  99
TYR A 110
None
None
JIM  A 193 (-4.3A)
JIM  A 193 ( 4.0A)
None
1.44A86.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		4f92 U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE
(Homo
sapiens)		5 / 12PHE B 979
TYR B 972
VAL B 970
LEU B 411
HIS B 958
None
1.43A9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		4goj PROTEIN UNC-119
HOMOLOG A
(Homo
sapiens)		5 / 12PHE C 159
PHE C 149
HIS C 192
SER C 218
TYR C 220
None
1.45A18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		5do7 ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
5
ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
8
(Homo
sapiens)		5 / 12PHE A 403
PHE B 595
PHE B 654
LEU B 650
SER B 569
None
1.34A13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		5wai POLYCOMB PROTEIN
SUZ12
(Homo
sapiens)		5 / 12PHE B 237
VAL B 301
PHE B 161
LEU B 184
SER B 233
None
1.48A19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		2pqf POLY [ADP-RIBOSE]
POLYMERASE 12
(Homo
sapiens)		5 / 9HIS A 564
ILE A 574
TYR A 596
SER A 604
TYR A 607
GAB  A 701 ( 3.7A)
CIT  A 801 (-4.8A)
GAB  A 701 (-4.5A)
GAB  A 701 (-2.8A)
GAB  A 701 (-3.3A)
0.76A22.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		3c49 POLY(ADP-RIBOSE)
POLYMERASE 3
(Homo
sapiens)		5 / 9HIS A 384
ILE A 394
TYR A 414
SER A 422
TYR A 425
KU8  A 601 (-4.0A)
None
KU8  A 601 (-4.1A)
KU8  A 601 (-2.9A)
KU8  A 601 (-3.5A)
0.48A37.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		3hkv POLY [ADP-RIBOSE]
POLYMERASE 10
(Homo
sapiens)		5 / 9HIS A 887
ILE A 897
TYR A 919
SER A 927
TYR A 932
3AB  A1025 (-3.8A)
None
3AB  A1025 (-4.4A)
3AB  A1025 (-2.8A)
3AB  A1025 (-3.7A)
0.75A19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		4f0d POLY [ADP-RIBOSE]
POLYMERASE 16
(Homo
sapiens)		6 / 9HIS A 152
SER A 154
ASN A 158
ILE A 162
TYR A 182
TYR A 193
3AB  A 301 (-4.0A)
None
None
None
3AB  A 301 (-4.3A)
3AB  A 301 (-3.8A)
0.72A25.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		4l2k TANKYRASE-2
(Homo
sapiens)		6 / 9HIS A1031
SER A1033
ILE A1039
TYR A1060
SER A1068
TYR A1071
1V8  A1201 (-4.2A)
1V8  A1201 (-3.2A)
None
1V8  A1201 (-4.7A)
1V8  A1201 (-2.7A)
1V8  A1201 (-3.3A)
0.66A21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		4oa7 TANKYRASE-1
(Homo
sapiens)		5 / 9HIS A1184
ILE A1192
TYR A1213
SER A1221
TYR A1224
2XS  A1402 (-4.2A)
2XS  A1402 ( 4.7A)
2XS  A1402 (-4.2A)
None
2XS  A1402 ( 3.9A)
0.96A22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		4oa7 TANKYRASE-1
(Homo
sapiens)		5 / 9SER A1186
ILE A1192
TYR A1213
SER A1221
TYR A1224
2XS  A1402 (-3.6A)
2XS  A1402 ( 4.7A)
2XS  A1402 (-4.2A)
None
2XS  A1402 ( 3.9A)
0.92A22.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		4oqa POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens)		6 / 9ASP C 770
SER C 864
ASN C 868
ILE C 872
SER C 904
TYR C 907
None
None
None
None
2US  C1101 (-3.4A)
2US  C1101 (-3.5A)
0.86A86.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		4oqa POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens)		7 / 9HIS C 862
SER C 864
ASN C 868
ILE C 872
TYR C 896
SER C 904
TYR C 907
2US  C1101 (-3.7A)
None
None
None
2US  C1101 (-4.2A)
2US  C1101 (-3.4A)
2US  C1101 (-3.5A)
0.47A86.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		4zzy POLY [ADP-RIBOSE]
POLYMERASE 2
(Homo
sapiens)		7 / 9HIS A 428
SER A 430
ASN A 434
ILE A 438
TYR A 462
SER A 470
TYR A 473
D7N  A1584 (-3.6A)
None
None
None
D7N  A1584 (-3.7A)
D7N  A1584 (-2.7A)
D7N  A1584 (-3.8A)
0.46A45.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		5dcz TANKYRASE-2
(Homo
sapiens)		6 / 9HIS A1031
SER A1033
ILE A1039
TYR A1060
SER A1068
TYR A1071
59B  A1203 (-4.1A)
59B  A1203 (-3.5A)
None
59B  A1203 (-4.3A)
59B  A1203 (-2.8A)
59B  A1203 (-3.3A)
0.65A22.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		5dsy POLY [ADP-RIBOSE]
POLYMERASE 2
(Homo
sapiens)		7 / 9HIS A 415
SER A 417
ASN A 421
ILE A 425
TYR A 449
SER A 457
TYR A 460
UHB  A1001 (-3.7A)
UHB  A1001 (-2.5A)
UHB  A1001 (-3.7A)
UHB  A1001 (-4.6A)
UHB  A1001 (-3.8A)
UHB  A1001 (-2.5A)
UHB  A1001 (-3.4A)
0.53A40.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		5lx6 POLY [ADP-RIBOSE]
POLYMERASE 10
(Homo
sapiens)		5 / 9HIS A 887
ILE A 897
TYR A 919
SER A 927
TYR A 932
78P  A1101 (-4.0A)
None
78P  A1101 (-3.7A)
78P  A1101 (-2.8A)
78P  A1101 (-3.8A)
0.84A20.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens)		8 / 9GLU A 102
ASP A 109
HIS A 201
SER A 203
ASN A 207
ILE A 211
SER A 243
TYR A 246
8E6  A 401 (-4.2A)
None
8E6  A 401 (-3.5A)
None
None
None
8E6  A 401 (-2.6A)
8E6  A 401 (-3.4A)
0.80A98.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens)		7 / 9HIS A 201
SER A 203
ASN A 207
ILE A 211
TYR A 235
SER A 243
TYR A 246
8E6  A 401 (-3.5A)
None
None
None
8E6  A 401 (-4.1A)
8E6  A 401 (-2.6A)
8E6  A 401 (-3.4A)
0.51A98.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens)		7 / 9HIS A 862
SER A 864
ASN A 868
ILE A 872
TYR A 896
SER A 904
TYR A 907
DQV  A1101 (-3.6A)
DQV  A1101 (-2.9A)
DQV  A1101 (-4.2A)
DQV  A1101 (-4.5A)
DQV  A1101 (-3.5A)
DQV  A1101 (-2.7A)
DQV  A1101 (-3.7A)
0.47A31.32