POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FR8_A_TNGA601_1 (ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL)	4kwg	ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL (Homo sapiens)	8 / 11	ASN A 169 PHE A 170 LEU A 173 MET A 174 TRP A 177 CYH A 302 ASP A 457 PHE A 459	None 2AK  A 601 (-4.1A) 2AK  A 601 (-4.9A) 2AK  A 601 ( 3.9A) None 2AK  A 601 (-4.6A) 2AK  A 601 (-2.6A) 2AK  A 601 (-4.0A)	0.24A	99.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FR8_A_TNGA601_1 (ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL)	5fhz	ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER A3 (Homo sapiens)	5 / 11	ASN A 181 LEU A 185 MET A 186 TRP A 189 PHE A 477	REA  A 602 (-3.9A) None REA  A 602 (-4.4A) REA  A 602 ( 4.5A) None	1.41A	63.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FR8_A_TNGA601_1 (ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL)	5fhz	ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER A3 (Homo sapiens)	6 / 11	ASN A 181 PHE A 182 LEU A 185 MET A 186 TRP A 189 CYH A 314	REA  A 602 (-3.9A) REA  A 602 (-4.0A) None REA  A 602 (-4.4A) REA  A 602 ( 4.5A) REA  A 602 (-2.8A)	0.82A	63.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FR8_A_TNGA601_1 (ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL)	5y3r	DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT (Homo sapiens)	5 / 11	ASN C2217 LEU C2219 MET C2220 SER C2250 ASP C2208	None	1.23A	7.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FR8_A_TNGA601_1 (ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL)	6b5i	RETINAL DEHYDROGENASE 2 (Homo sapiens)	6 / 11	ASN A 187 PHE A 188 LEU A 191 MET A 192 TRP A 195 CYH A 320	CU4  A 601 (-4.2A) CU4  A 601 (-3.6A) None CU4  A 601 ( 4.7A) CU4  A 601 (-4.2A) CU4  A 601 (-4.2A)	0.62A	55.17