POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	1o5t	TRYPTOPHANYL-TRNA SYNTHETASE (Homo sapiens)	4 / 7	ASP A 198 MET A 195 ASP A 197 ASP A 237	None	1.48A	20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	1p32	MITOCHONDRIAL MATRIX PROTEIN, SF2P32 (Homo sapiens)	4 / 7	TYR A 236 MET A 240 ASP A 241 ASP A 237	None	1.21A	18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	1r6u	TRYPTOPHANYL-TRNA SYNTHETASE (Homo sapiens)	4 / 7	ASP A 198 MET A 195 ASP A 197 ASP A 237	None	1.45A	20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	2vx8	NUCLEOPORIN-LIKE PROTEIN RIP, VESICLE-ASSOCIATED MEMBRANE PROTEIN 7 (Homo sapiens; Mus musculus)	4 / 7	ASP A 112 TYR A  93 ASP A 111 ASP A 110	None	1.44A	13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	2xh1	KYNURENINE/ALPHA-AMI NOADIPATE AMINOTRANSFERASE, MITOCHONDRIAL (Homo sapiens)	4 / 7	TYR A 233 ASP A 230 ASP A 231 HIS A  95	PLP  A1427 (-4.9A) PLP  A1427 (-2.8A) None None	1.18A	23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	3c5r	BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1 (Homo sapiens)	4 / 7	ASP A 500 TYR A 492 ASP A 495 HIS A 471	None	1.19A	13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	3kyd	SUMO-ACTIVATING ENZYME SUBUNIT 1 (Homo sapiens)	4 / 7	ASP A 239 TYR A 161 MET A 334 ASP A 332	EDO  A 347 (-3.9A) None None None	1.48A	22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	3kyd	SUMO-ACTIVATING ENZYME SUBUNIT 1 (Homo sapiens)	4 / 7	ASP A 239 TYR A 294 MET A 334 ASP A 332	EDO  A 347 (-3.9A) None None None	1.32A	22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	4p0v	FARNESYL PYROPHOSPHATE SYNTHASE (Homo sapiens)	4 / 7	MET A 106 ASP A 107 ASP A 104 LYS A 257	None MG  A 405 (-2.4A) None 1WO  A 402 ( 2.8A)	1.22A	21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	4qtb	MITOGEN-ACTIVATED PROTEIN KINASE 3 (Homo sapiens)	4 / 7	ASP A 335 ASP A 338 LYS A 155 HIS A  97	None	1.43A	20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	4z7g	SERINE/THREONINE-PRO TEIN KINASE/ENDORIBONUCLE ASE IRE1 (Homo sapiens)	4 / 7	ASP A 844 ASP A 847 LYS A 908 HIS A 909	None	1.28A	21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	5i85	SPHINGOMYELIN PHOSPHODIESTERASE (Homo sapiens)	4 / 7	TYR A 213 ASP A 251 ASP A 210 HIS A 286	None	1.10A	21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	5td2	TYROSINE-PROTEIN KINASE MER (Homo sapiens)	4 / 7	TYR A 676 MET A 735 ASP A 734 ASP A 733	None	1.47A	20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	5veb	CADHERIN-6 (Homo sapiens)	4 / 7	ASP X 572 TYR X 575 ASP X 574 HIS X 521	None	1.48A	11.15