POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	1elv	COMPLEMENT C1S COMPONENT (Homo sapiens)	7 / 12	ASP A 611 SER A 617 VAL A 638 TRP A 640 GLY A 641 GLY A 648 TYR A 650	None SO4  A2001 ( 2.7A) None None None None None	0.35A	28.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	1fxy	COAGULATION FACTOR XA-TRYPSIN CHIMERA (Homo sapiens)	8 / 12	ASP A 189 SER A 195 VAL A 213 TRP A 215 GLY A 216 GLY A 219 GLY A 226 TYR A 228	0G6  A   1 (-2.8A) 0G6  A   1 (-1.4A) None None 0G6  A   1 (-3.9A) None 0G6  A   1 (-3.3A) None	0.41A	65.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	1fxy	COAGULATION FACTOR XA-TRYPSIN CHIMERA (Homo sapiens)	8 / 12	TYR A  99 ASP A 189 VAL A 213 TRP A 215 GLY A 216 GLY A 219 GLY A 226 TYR A 228	0G6  A   1 (-4.0A) 0G6  A   1 (-2.8A) None None 0G6  A   1 (-3.9A) None 0G6  A   1 (-3.3A) None	0.54A	65.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	1gvl	KALLIKREIN 6 (Homo sapiens)	5 / 12	SER A 195 VAL A 213 GLY A 216 GLY A 226 TYR A 228	None	0.71A	34.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	1gvl	KALLIKREIN 6 (Homo sapiens)	5 / 12	VAL A 213 TRP A 215 GLY A 216 GLY A 226 TYR A 228	None	0.35A	34.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	1h4w	TRYPSIN IVA (Homo sapiens)	8 / 12	ASP A 189 SER A 195 VAL A 213 TRP A 215 GLY A 216 GLY A 219 GLY A 226 TYR A 228	BEN  A 250 (-2.9A) BEN  A 250 (-3.6A) None None BEN  A 250 (-3.9A) None BEN  A 250 (-3.3A) None	0.37A	36.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	1o5f	SERINE PROTEASE HEPSIN (Homo sapiens)	9 / 12	ASP H 189 ALA H 190 SER H 195 VAL H 213 TRP H 215 GLY H 216 GLY H 219 GLY H 226 TYR H 228	CR9  H 256 (-2.4A) CR9  H 256 (-2.9A) CR9  H 256 (-1.5A) CR9  H 256 (-4.3A) None CR9  H 256 ( 3.8A) CR9  H 256 (-4.3A) CR9  H 256 (-3.0A) None	0.28A	36.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	1orf	GRANZYME A (Homo sapiens)	5 / 12	ASP A 189 SER A 195 GLY A 216 GLY A 226 TYR A 228	0G6  A   1 (-2.9A) 0G6  A   1 (-1.3A) 0G6  A   1 (-3.3A) 0G6  A   1 (-3.5A) None	0.35A	29.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	1q3x	MANNAN-BINDING LECTIN SERINE PROTEASE 2 (Homo sapiens)	7 / 12	ASP A 627 SER A 633 VAL A 653 TRP A 655 GLY A 656 GLY A 667 TYR A 669	NA  A 800 ( 4.6A) GOL  A 701 (-3.0A) GOL  A 701 (-4.9A) None GOL  A 701 ( 4.1A) GOL  A 701 ( 4.0A) None	0.47A	26.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	1ybw	HEPATOCYTE GROWTH FACTOR ACTIVATOR PRECURSOR (Homo sapiens)	5 / 12	ASP A 592 ALA A 593 SER A 598 CYH A 622 TYR A 631	None	0.77A	33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	1ybw	HEPATOCYTE GROWTH FACTOR ACTIVATOR PRECURSOR (Homo sapiens)	5 / 12	ASP A 592 ALA A 593 SER A 598 GLY A 629 TYR A 631	None	0.68A	33.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	1zjk	MANNAN-BINDING LECTIN SERINE PROTEASE 2 (Homo sapiens)	5 / 12	VAL A 653 TRP A 655 GLY A 656 GLY A 667 TYR A 669	None	0.23A	26.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	1zlr	COAGULATION FACTOR XI (Homo sapiens)	8 / 12	ASP A 189 ALA A 190 SER A 195 TRP A 215 GLY A 216 GLY A 218 GLY A 226 TYR A 228	368  A 901 (-2.8A) 368  A 901 (-3.7A) 368  A 901 (-1.4A) None 368  A 901 (-3.6A) 368  A 901 (-4.3A) 368  A 901 (-3.5A) None	0.43A	34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	2ei8	COAGULATION FACTOR X, HEAVY CHAIN (Homo sapiens)	11 / 12	TYR A  99 PHE A 174 ASP A 189 ALA A 190 SER A 195 VAL A 213 TRP A 215 GLY A 216 GLY A 218 GLY A 226 TYR A 228	DT8  A 700 (-3.4A) DT8  A 700 (-3.4A) DT8  A 700 (-3.5A) DT8  A 700 (-3.6A) DT8  A 700 ( 3.9A) DT8  A 700 ( 4.1A) DT8  A 700 (-3.9A) DT8  A 700 (-3.5A) DT8  A 700 (-4.1A) DT8  A 700 (-3.5A) DT8  A 700 (-3.5A)	0.32A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	2odp	COMPLEMENT C2 (Homo sapiens)	5 / 12	TYR A 538 SER A 659 VAL A 677 TRP A 679 GLY A 680	None	0.45A	18.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	2oq5	TRANSMEMBRANE PROTEASE, SERINE 11E (Homo sapiens)	8 / 12	ASP A 189 ALA A 190 SER A 195 VAL A 213 TRP A 215 GLY A 216 GLY A 226 TYR A 228	BEN  A 245 (-3.0A) BEN  A 245 (-3.9A) BEN  A 245 (-3.3A) None None BEN  A 245 ( 3.8A) BEN  A 245 (-3.4A) None	0.35A	34.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	2pks	THROMBIN HEAVY CHAIN FRAGMENT (Homo sapiens)	9 / 12	ASP C 229 ALA C 230 SER C 235 VAL C 255 TRP C 257 GLY C 258 GLY C 260 GLY C 268 TYR C 270	G44  C 101 (-2.6A) G44  C 101 (-3.8A) G44  C 101 (-3.5A) None G44  C 101 (-4.1A) G44  C 101 (-3.3A) None G44  C 101 (-3.0A) None	0.37A	23.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	2psy	KALLIKREIN-5 (Homo sapiens)	7 / 12	ASP A 189 SER A 195 VAL A 213 TRP A 215 GLY A 216 GLY A 226 TYR A 228	None	0.33A	31.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	2qy0	COMPLEMENT C1R SUBCOMPONENT (Homo sapiens)	9 / 12	ASP B 631 ALA B 632 SER B 637 VAL B 657 TRP B 659 GLY B 660 GLY B 662 GLY B 668 TYR B 670	None	0.48A	40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	2r0l	HEPATOCYTE GROWTH FACTOR ACTIVATOR (Homo sapiens)	8 / 12	ASP A 189 ALA A 190 SER A 195 TRP A 215 GLY A 216 GLY A 219 GLY A 226 TYR A 228	None	0.47A	33.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	2r2w	PLASMINOGEN ACTIVATOR, UROKINASE (Homo sapiens)	7 / 12	ASP U 189 VAL U 213 TRP U 215 GLY U 216 GLY U 219 GLY U 226 TYR U 228	4PG  U 300 (-2.8A) None None 4PG  U 300 (-3.3A) None 4PG  U 300 (-3.2A) None	0.39A	32.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	2wpm	COAGULATION FACTOR IXA HEAVY CHAIN (Homo sapiens)	8 / 12	TYR S  99 PHE S 174 ASP S 189 SER S 195 TRP S 215 GLY S 216 GLY S 226 TYR S 228	None	0.44A	46.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	2xrc	HUMAN COMPLEMENT FACTOR I (Homo sapiens)	5 / 12	TYR A 408 VAL A 526 TRP A 528 GLY A 539 TYR A 541	None	0.39A	16.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	2zec	TRYPTASE BETA 2 (Homo sapiens)	8 / 12	ASP A 203 SER A 209 VAL A 227 TRP A 229 GLY A 230 GLY A 232 GLY A 240 TYR A 242	11N  A   1 (-2.6A) 11N  A   1 (-3.3A) None None 11N  A   1 (-3.9A) 11N  A   1 (-3.8A) 11N  A   1 (-3.6A) None	0.47A	34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	3f6u	VITAMIN K-DEPENDENT PROTEIN C HEAVY CHAIN (Homo sapiens)	9 / 12	ASP H 189 ALA H 190 SER H 195 VAL H 213 TRP H 215 GLY H 216 GLY H 219 GLY H 226 TYR H 228	0G6  H   1 (-2.8A) 0G6  H   1 (-3.4A) 0G6  H   1 (-1.8A) None 0G6  H   1 (-4.1A) 0G6  H   1 (-3.8A) None 0G6  H   1 ( 3.9A) None	0.51A	37.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	3gov	MASP-1 (Homo sapiens)	8 / 12	ASP B 640 ALA B 641 SER B 646 VAL B 666 TRP B 668 GLY B 669 GLY B 679 TYR B 681	None	0.42A	32.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	3gym	PROSTASIN (Homo sapiens)	8 / 12	ASP A 189 ALA A 190 SER A 195 VAL A 213 TRP A 215 GLY A 216 GLY A 226 TYR A 228	None	0.36A	33.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	3r3g	THROMBIN HEAVY CHAIN (Homo sapiens)	9 / 12	ASP B 189 ALA B 190 SER B 195 VAL B 213 TRP B 215 GLY B 216 GLY B 219 GLY B 226 TYR B 228	None	0.38A	40.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	4d9r	COMPLEMENT FACTOR D (Homo sapiens)	5 / 12	ASP A 189 SER A 195 VAL A 213 GLY A 226 TYR A 228	None	0.25A	32.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	4fxg	MANNAN-BINDING LECTIN SERINE PROTEASE 2 B CHAIN (Homo sapiens)	6 / 12	ASP H 627 VAL H 653 TRP H 655 GLY H 656 GLY H 667 TYR H 669	None	0.35A	34.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	4h4f	CHYMOTRYPSIN-C (Homo sapiens)	5 / 12	ALA A 190 SER A 195 VAL A 213 GLY A 216 TYR A 228	None	0.30A	34.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	4igd	MANNAN-BINDING LECTIN SERINE PROTEASE 1 (Homo sapiens)	6 / 12	SER A 646 VAL A 666 TRP A 668 GLY A 673 GLY A 679 TYR A 681	None None GOL  A 702 (-3.9A) None None None	0.75A	21.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	4iw4	MANNAN-BINDING LECTIN SERINE PROTEASE 3 (Homo sapiens)	8 / 12	ASP E 639 SER E 645 VAL E 665 TRP E 667 GLY E 668 GLY E 669 GLY E 680 TYR E 682	None	0.75A	35.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	4iw4	MANNAN-BINDING LECTIN SERINE PROTEASE 3 (Homo sapiens)	8 / 12	TYR E 531 ASP E 639 VAL E 665 TRP E 667 GLY E 668 GLY E 669 GLY E 680 TYR E 682	None	0.94A	35.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	4k8y	KALLIKREIN-4 (Homo sapiens)	6 / 12	ASP A 189 SER A 195 VAL A 213 GLY A 216 GLY A 226 TYR A 228	None	0.43A	29.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	4kkd	MANNAN-BINDING LECTIN SERINE PROTEASE 1 (Homo sapiens)	6 / 12	TYR A 550 VAL A 684 GLY A 687 GLY A 688 GLY A 699 TYR A 701	None	1.02A	23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	4kkd	MANNAN-BINDING LECTIN SERINE PROTEASE 1 (Homo sapiens)	6 / 12	TYR A 550 VAL A 684 TRP A 686 GLY A 687 GLY A 699 TYR A 701	None	0.61A	23.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	4nff	KALLIKREIN-2 (Homo sapiens)	5 / 12	ASP A 189 SER A 195 TRP A 215 GLY A 216 TYR A 228	0G6  A 301 (-3.0A) 0G6  A 301 (-1.4A) 0G6  A 301 (-3.7A) 0G6  A 301 (-3.4A) None	0.37A	34.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	4r0i	SUPPRESSOR OF TUMORIGENICITY 14 PROTEIN (Homo sapiens)	8 / 12	ASP A 189 SER A 195 VAL A 213 TRP A 215 GLY A 216 GLY A 219 GLY A 226 TYR A 228	3KM  A 900 (-2.9A) 3KM  A 900 (-3.6A) None None 3KM  A 900 (-3.4A) 3KM  A 900 (-3.9A) 3KM  A 900 (-3.2A) None	0.32A	33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	4wwy	TRYPSIN-1 (Homo sapiens)	8 / 12	ASP A 189 SER A 195 VAL A 213 TRP A 215 GLY A 216 GLY A 219 GLY A 226 TYR A 228	None	0.37A	35.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	4ylq	COAGULATION FACTOR VII (Homo sapiens)	8 / 12	ASP H 189 SER H 195 VAL H 213 TRP H 215 GLY H 216 GLY H 218 GLY H 226 TYR H 228	0Z7  H 501 (-2.3A) 0Z7  H 501 (-1.4A) 0Z7  H 501 ( 4.7A) TMA  H 508 ( 3.9A) 0Z7  H 501 (-3.4A) 0Z7  H 501 (-3.5A) 0Z7  H 501 (-3.0A) None	0.32A	40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	5brr	TISSUE-TYPE PLASMINOGEN ACTIVATOR (Homo sapiens)	7 / 12	TYR E  99 ASP E 189 ALA E 190 TRP E 215 GLY E 216 GLY E 226 TYR E 228	None	0.44A	38.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	5eod	COAGULATION FACTOR XI (Homo sapiens)	5 / 12	SER A 557 TRP A 577 GLY A 578 GLY A 588 TYR A 590	None	0.74A	15.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	5f8z	PLASMA KALLIKREIN LIGHT CHAIN (Homo sapiens)	7 / 12	ASP A 189 ALA A 190 SER A 195 GLY A 216 GLY A 219 GLY A 226 TYR A 228	None	0.50A	35.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	5f8z	PLASMA KALLIKREIN LIGHT CHAIN (Homo sapiens)	7 / 12	ASP A 189 ALA A 190 TRP A 215 GLY A 216 GLY A 219 GLY A 226 TYR A 228	None	0.34A	35.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	5fah	KALLIKREIN-7 (Homo sapiens)	6 / 12	ALA A 190 SER A 195 VAL A 213 TRP A 215 GLY A 226 TYR A 228	5VT  A 302 (-3.8A) 5VT  A 302 (-4.0A) None None 5VT  A 302 ( 4.3A) None	0.78A	33.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	5fah	KALLIKREIN-7 (Homo sapiens)	6 / 12	ALA A 190 VAL A 213 TRP A 215 GLY A 216 GLY A 226 TYR A 228	5VT  A 302 (-3.8A) None None 5VT  A 302 (-3.4A) 5VT  A 302 ( 4.3A) None	0.45A	33.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	5ms3	KALLIKREIN-8 (Homo sapiens)	6 / 12	ASP A 189 SER A 195 TRP A 215 GLY A 216 GLY A 226 TYR A 228	None	0.33A	21.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	5o32	COMPLEMENT FACTOR I (Homo sapiens)	7 / 12	ASP I 519 ALA I 520 VAL I 544 TRP I 546 GLY I 547 GLY I 557 TYR I 559	None	0.79A	33.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	5o32	COMPLEMENT FACTOR I (Homo sapiens)	7 / 12	TYR I 426 ASP I 519 VAL I 544 TRP I 546 GLY I 547 GLY I 557 TYR I 559	None	0.78A	33.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	5to3	PROTHROMBIN,THROMBOM ODULIN (Homo sapiens)	8 / 12	ASP B 214 ALA B 215 SER B 220 VAL B 240 GLY B 243 GLY B 245 GLY B 253 TYR B 255	0G6  B 501 (-2.9A) 0G6  B 501 (-3.4A) 0G6  B 501 (-1.3A) None 0G6  B 501 (-3.7A) None 0G6  B 501 (-3.6A) None	0.36A	26.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	5ubm	COMPLEMENT C1S SUBCOMPONENT (Homo sapiens)	7 / 12	ASP A 626 SER A 632 VAL A 653 TRP A 655 GLY A 656 GLY A 663 TYR A 665	None	0.51A	33.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	6b74	COAGULATION FACTOR XII (Homo sapiens)	9 / 12	TYR B  99 ASP B 189 ALA B 190 SER B 195 TRP B 215 GLY B 216 GLY B 219 GLY B 226 TYR B 228	None BEN  B 301 (-2.7A) BEN  B 301 (-4.1A) SO4  B 304 ( 2.5A) None BEN  B 301 (-3.3A) SO4  B 307 ( 3.4A) BEN  B 301 (-3.1A) None	0.58A	17.87