POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_A_RGZA601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	1gq4	EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN-50 (Homo sapiens)	5 / 11	LEU A  59 LEU A  17 CYH A  16 ILE A  79 TYR A  24	None	1.45A	11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_A_RGZA601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	2gkw	TNF RECEPTOR-ASSOCIATED FACTOR 3 (Homo sapiens)	5 / 11	LEU A 396 LEU A 434 ILE A 485 GLN A 437 ILE A 358	None	1.49A	15.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4A7A_A_RGZA601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	2z5x	AMINE OXIDASE [FLAVIN-CONTAINING] A (Homo sapiens)	6 / 11	TYR A  69 GLN A 215 ILE A 325 PHE A 352 TYR A 407 TYR A 444	FAD  A 600 (-4.2A) HRM  A 700 (-3.4A) None HRM  A 700 (-4.3A) HRM  A 700 ( 3.9A) FAD  A 600 ( 4.6A)	0.21A	72.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_A_RGZA601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	3ihp	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 5 (Homo sapiens)	5 / 11	TYR A 568 LEU A 533 ILE A 571 ILE A 599 TYR A 778	None	1.23A	19.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4A7A_A_RGZA601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	3zyx	AMINE OXIDASE [FLAVIN-CONTAINING] B (Homo sapiens)	9 / 11	TYR A  60 LEU A 164 LEU A 171 CYH A 172 GLN A 206 ILE A 316 PHE A 343 TYR A 398 TYR A 435	FAD  A 600 (-4.4A) None MBT  A 601 (-4.2A) None MBT  A 601 (-3.4A) MBT  A 601 (-4.6A) MBT  A 601 (-4.7A) MBT  A 601 ( 3.6A) MBT  A 601 ( 4.6A)	0.20A	99.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_A_RGZA601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	4obs	ALPHA-L-IDURONIDASE (Homo sapiens)	5 / 11	TYR A  64 LEU A 604 LEU A  74 PHE A  52 TYR A 117	None	1.23A	22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_A_RGZA601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	4rh7	GREEN FLUORESCENT PROTEIN/CYTOPLASMIC DYNEIN 2 HEAVY CHAIN 1 (Homo sapiens; synthetic construct)	5 / 11	LEU A2730 LEU A2710 GLN A2716 ILE A2726 PHE A2677	None	1.46A	9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_A_RGZA601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	4s0v	HUMAN OREXIN RECEPTOR TYPE 2 FUSION PROTEIN TO P. ABYSII GLYCOGEN SYNTHASE (Homo sapiens; Pyrococcus abyssi)	5 / 11	LEU A1058 LEU A1051 ILE A1170 PHE A1037 TYR A1120	None	1.40A	21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_A_RGZA601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	4xvm	DNA POLYMERASE NU (Homo sapiens)	5 / 11	LEU A 842 ILE A 631 PHE A 654 TYR A 682 TYR A 686	None	1.38A	21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_A_RGZA601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	4zch	TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13,TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B,TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B (Homo sapiens)	5 / 11	LEU A 186 ILE A 203 ILE A 193 PHE A 286 TYR A 405	None	1.41A	21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_A_RGZA601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	5of4	TFIIH BASAL TRANSCRIPTION FACTOR COMPLEX HELICASE XPD SUBUNIT (Homo sapiens)	5 / 11	ILE B 432 GLN B 347 ILE B 417 PHE B 357 TYR B 339	None	1.23A	22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_A_RGZA601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	5u09	CANNABINOID RECEPTOR 1,GLGA GLYCOGEN SYNTHASE (Homo sapiens; Pyrococcus abyssi)	5 / 11	LEU A1058 LEU A1051 ILE A1170 PHE A1037 TYR A1120	None	1.42A	21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_B_RGZB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	1qag	UTROPHIN ACTIN BINDING REGION (Homo sapiens)	5 / 12	LEU A  73 LEU A  70 LEU A  66 ILE A  41 ILE A 130	None	0.95A	16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_B_RGZB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	1w8d	2,4-DIENOYL-COA REDUCTASE, MITOCHONDRIAL PRECURSOR (Homo sapiens)	5 / 12	PRO A 240 LEU A 277 LEU A 280 LEU A 284 CYH A 285	NAP  A1330 (-4.5A) None None None None	1.08A	19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_B_RGZB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	1zvd	SMAD UBIQUITINATION REGULATORY FACTOR 2 (Homo sapiens)	5 / 12	LEU A 442 LEU A 445 ILE A 500 ILE A 489 TYR A 459	None	1.14A	19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_B_RGZB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	2b3x	IRON-RESPONSIVE ELEMENT BINDING PROTEIN 1 (Homo sapiens)	5 / 12	PRO A 171 GLN A 179 ILE A 616 TYR A 613 PHE A 609	None	0.99A	20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_B_RGZB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	2hz0	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 (Homo sapiens)	5 / 12	LEU A 364 LEU A 428 LEU A 429 ILE A 489 ILE A 347	None	1.07A	19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_B_RGZB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	2y0n	MALE-SPECIFIC LETHAL 1 HOMOLOG MALE-SPECIFIC LETHAL 3 HOMOLOG (Homo sapiens; Mus musculus)	5 / 12	PRO E 582 LEU E 584 LEU A 459 ILE A 466 PHE A 460	None	1.14A	7.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4A7A_B_RGZB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	2z5x	AMINE OXIDASE [FLAVIN-CONTAINING] A (Homo sapiens)	7 / 12	PRO A 113 LEU A 176 GLN A 215 ILE A 325 PHE A 352 TYR A 407 TYR A 444	None None HRM  A 700 (-3.4A) None HRM  A 700 (-4.3A) HRM  A 700 ( 3.9A) FAD  A 600 ( 4.6A)	0.48A	72.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_B_RGZB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	2z7x	TOLL-LIKE RECEPTOR 1, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	LEU B  95 LEU B  71 LEU B  50 ILE B  76 ILE B  65	None	1.14A	21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_B_RGZB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	3c49	POLY(ADP-RIBOSE) POLYMERASE 3 (Homo sapiens)	5 / 12	LEU A 322 LEU A 395 LEU A 528 ILE A 196 TYR A 438	None	1.14A	21.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4A7A_B_RGZB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	3zyx	AMINE OXIDASE [FLAVIN-CONTAINING] B (Homo sapiens)	10 / 12	PRO A 104 LEU A 164 LEU A 167 LEU A 171 CYH A 172 GLN A 206 ILE A 316 PHE A 343 TYR A 398 TYR A 435	None None None MBT  A 601 (-4.2A) None MBT  A 601 (-3.4A) MBT  A 601 (-4.6A) MBT  A 601 (-4.7A) MBT  A 601 ( 3.6A) MBT  A 601 ( 4.6A)	0.42A	99.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_B_RGZB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	4krf	PROTEIN ARGONAUTE-1 (Homo sapiens)	5 / 12	LEU A 777 LEU A 780 LEU A 784 CYH A 785 ILE A 663	None	0.80A	20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_B_RGZB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	4wlh	KYNURENINE--OXOGLUTA RATE TRANSAMINASE 1 (Homo sapiens)	5 / 12	LEU A 162 LEU A 198 LEU A 202 CYH A 203 ILE A 119	None	1.10A	20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_B_RGZB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	4z94	GELSOLIN, TROPOMODULIN-1, LEIOMODIN-1 CHIMERA (Homo sapiens)	5 / 12	LEU G1366 LEU G1394 LEU G1420 ILE G1389 ILE G1379	None	1.11A	22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_B_RGZB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	5e1t	TNF RECEPTOR-ASSOCIATED FACTOR 1 (Homo sapiens)	5 / 12	LEU A 291 LEU A 309 LEU A 322 ILE A 273 PHE A 388	None	0.89A	17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_B_RGZB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	5vm9	PROTEIN ARGONAUTE-3 (Homo sapiens)	5 / 12	LEU A 780 LEU A 783 LEU A 787 CYH A 788 ILE A 666	None	0.80A	20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7A_B_RGZB601_1 (AMINE OXIDASE [FLAVIN-CONTAINING] B)	5wea	PROTEIN ARGONAUTE-2 (Homo sapiens)	5 / 12	LEU A 779 LEU A 782 LEU A 786 CYH A 787 ILE A 665	None	0.73A	9.47