POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B0Q_A_NMYA305_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E)		5b4x LOW DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 8,
APOLIPOPROTEIN E
RECEPTOR, ISOFORM
CRA_E
REELIN
(Homo
sapiens;
Mus
musculus)		5 / 12GLU B 519
GLU B 537
ASP A2474
SER A2350
ASP A2327
None
None
CA  A4003 (-2.0A)
None
None
1.48A19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B0Q_A_NMYA305_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E)		5c1b TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
(Homo
sapiens)		5 / 12GLU A  80
GLU A 221
GLU A 218
ASP A  29
SER A  78
None
1.35A16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		1kq0 METHIONINE
AMINOPEPTIDASE 2
(Homo
sapiens)		5 / 12LEU A 447
PRO A 220
ASP A 262
ILE A 338
HIS A 331
None
None
ZN  A 479 (-2.2A)
MED  A 601 ( 4.7A)
ZN  A 480 ( 3.4A)
1.39A21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		1zr5 H2AFY PROTEIN
(Homo
sapiens)		5 / 12LEU A 205
ASN A 317
LEU A 329
PHE A 349
ILE A 328
None
1.44A20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		2adu METHIONINE
AMINOPEPTIDASE 2
(Homo
sapiens)		5 / 12LEU A 447
PRO A 220
ASP A 262
ILE A 338
HIS A 331
None
None
CO  A 501 (-2.2A)
R20  A 906 ( 4.5A)
CO  A 502 ( 3.2A)
1.39A22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		2fy2 CHOLINE
O-ACETYLTRANSFERASE
(Homo
sapiens)		5 / 12TYR A 552
ASP A 414
LEU A 597
PHE A 573
ILE A 417
None
1.14A20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		2ibn INOSITOL OXYGENASE
(Homo
sapiens)		5 / 12LEU A 254
HIS A 194
PRO A 224
ASP A 195
LEU A 185
None
FE  A 704 ( 3.5A)
None
I1N  A 710 ( 4.8A)
None
1.40A21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		2x2u PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
(Homo
sapiens)		5 / 12LEU A 118
ASN A  83
LEU A  95
PHE A 147
ILE A  86
None
1.27A20.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		3ngo CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE
(Homo
sapiens)		12 / 12LEU A 206
TYR A 207
ASN A 325
HIS A 360
PRO A 365
LYS A 371
ASP A 410
ASN A 412
LEU A 414
PHE A 484
ILE A 488
HIS A 529
None
None
None
None
None
None
MG  A 556 (-2.8A)
MG  A 556 (-3.2A)
None
None
None
MG  A 556 (-4.2A)
0.32A100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		3ngo CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE
(Homo
sapiens)		6 / 12TYR A 207
ASP A 489
LEU A 414
PHE A 484
ILE A 488
HIS A 529
None
None
None
None
None
MG  A 556 (-4.2A)
1.25A100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		3s95 LIM DOMAIN KINASE 1
(Homo
sapiens)		5 / 12LEU A 391
ASN A 462
ASP A 531
ILE A 457
HIS A 452
None
1.21A22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		3tni CYCLIN-T1
(Homo
sapiens)		5 / 12LEU B 184
HIS B 154
ASN B  60
LEU B  88
ILE B  59
None
1.43A22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		3x1o ROQUIN-1
(Homo
sapiens)		5 / 12LEU A 204
TYR A 276
LEU A 324
ILE A 320
HIS A 316
None
1.14A19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		4fdj N-ACETYLGALACTOSAMIN
E-6-SULFATASE
(Homo
sapiens)		5 / 12ASN A 303
PRO A  77
ASP A  40
ASN A 289
HIS A 236
None
None
CA  A 603 (-3.0A)
CA  A 603 (-2.9A)
NGA  A 604 (-3.3A)
1.42A22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		4hl4 TBC1 DOMAIN FAMILY
MEMBER 20
(Homo
sapiens)		5 / 12HIS A 227
ASP A 148
LEU A 155
PHE A 110
HIS A 147
None
1.29A20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		4qik ROQUIN-1
(Homo
sapiens)		5 / 12LEU A 204
TYR A 276
LEU A 324
ILE A 320
HIS A 316
None
1.16A23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		4qpm MITOTIC CHECKPOINT
SERINE/THREONINE-PRO
TEIN KINASE BUB1
(Homo
sapiens)		5 / 12LEU A 841
ASN A 922
ASP A 987
ILE A 914
HIS A 909
None
MG  A1502 ( 2.6A)
None
None
None
1.38A22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		4ux8 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
(Homo
sapiens)		5 / 12LEU A 118
ASN A  83
LEU A  95
PHE A 147
ILE A  86
None
1.26A19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		4z0v 2',5'-PHOSPHODIESTER
ASE 12
(Homo
sapiens)		8 / 12LEU A 317
TYR A 318
HIS A 456
PRO A 461
ASP A 496
ASN A 498
PHE A 556
HIS A 599
None
None
None
GOL  A 706 (-3.9A)
None
GOL  A 706 (-4.8A)
GOL  A 706 ( 4.7A)
None
0.64A25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		4z31 ROQUIN-2
(Homo
sapiens)		5 / 12LEU A 201
TYR A 273
LEU A 321
ILE A 317
HIS A 313
None
1.13A21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		5aho 5' EXONUCLEASE
APOLLO
(Homo
sapiens)		5 / 12ASN A 148
HIS A 276
ASP A 120
ILE A 297
HIS A  36
None
TLA  A1319 ( 3.9A)
ZN  A1320 (-2.5A)
None
ZN  A1320 ( 3.4A)
1.31A22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1
(Homo
sapiens)		5 / 12LEU A 597
HIS A 520
ASN A 426
LEU A 439
PHE A 615
None
1.37A21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		5i85 SPHINGOMYELIN
PHOSPHODIESTERASE
(Homo
sapiens)		5 / 12HIS A 208
ASP A 278
LEU A 341
PHE A 327
HIS A 425
 ZN  A 715 ( 3.4A)
ZN  A 714 (-2.6A)
None
None
ZN  A 714 (-3.2A)
1.34A20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		5uvg SPHINGOMYELIN
PHOSPHODIESTERASE
3,SPHINGOMYELIN
PHOSPHODIESTERASE 3
(Homo
sapiens)		5 / 12HIS A 461
ASP A 510
ASN A 512
ILE A 606
HIS A 639
None
0.24A21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		5vbn DNA POLYMERASE
EPSILON SUBUNIT 2
(Homo
sapiens)		5 / 12ASN A 324
PRO A 402
ASP A 482
LEU A 478
ILE A 480
None
1.11A21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		6fqc BIFUNCTIONAL
ARGININE DEMETHYLASE
AND
LYSYL-HYDROXYLASE
JMJD6
(Homo
sapiens)		5 / 12TYR A 131
PRO A 171
ASP A 189
ASN A 287
HIS A 187
None
None
MN  A 501 ( 2.6A)
OGA  A 506 ( 4.6A)
MN  A 501 ( 3.4A)
1.38A12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		1itu RENAL DIPEPTIDASE
(Homo
sapiens)		3 / 3GLU A 125
TRP A 162
ASN A 250
 ZN  A 401 ( 2.5A)
None
CIL  A 451 ( 4.7A)
0.58A22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		1kcw CERULOPLASMIN
(Homo
sapiens)		3 / 3GLU A  11
TRP A 211
ASN A  92
None
0.67A16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		1kcw CERULOPLASMIN
(Homo
sapiens)		3 / 3GLU A 721
TRP A 910
ASN A 807
None
0.82A16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		1wch PROTEIN TYROSINE
PHOSPHATASE,
NON-RECEPTOR TYPE 13
(Homo
sapiens)		3 / 3GLU A2313
TRP A2376
ASN A2372
None
None
PO4  A3480 (-2.8A)
1.06A21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		2dlw DOCKING PROTEIN 2,
ISOFORM A
(Homo
sapiens)		3 / 3GLU A  81
TRP A  54
ASN A  83
None
1.15A16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		2ej4 ZINC FINGER PROTEIN
ZIC 3
(Homo
sapiens)		3 / 3GLU A  21
TRP A  18
ASN A  57
None
1.14A10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		2f8a GLUTATHIONE
PEROXIDASE 1
(Homo
sapiens)		3 / 3GLU A 163
TRP A 160
ASN A 116
None
MLA  A 501 (-4.1A)
None
1.01A19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		2gjt RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE PTPRO
(Homo
sapiens)		3 / 3GLU A1041
TRP A1100
ASN A1096
None
1.13A18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		2he3 GLUTATHIONE
PEROXIDASE 2
(Homo
sapiens)		3 / 3GLU A 155
TRP A 152
ASN A 108
None
1.02A19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		2i3y EPIDIDYMAL SECRETORY
GLUTATHIONE
PEROXIDASE
(Homo
sapiens)		3 / 3GLU A 184
TRP A 181
ASN A 141
None
EDO  A 221 ( 3.7A)
None
0.88A19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		2nna MHC CLASS II ANTIGEN
(Homo
sapiens)		3 / 3GLU B 187
TRP B 188
ASN B 134
None
1.09A19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		2r37 GLUTATHIONE
PEROXIDASE 3
(Homo
sapiens)		3 / 3GLU A 184
TRP A 181
ASN A 141
None
CL  A   1 (-4.7A)
None
0.83A19.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		3ngo CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE
(Homo
sapiens)		3 / 3GLU A 240
TRP A 363
ASN A 479
 MG  A 557 (-2.6A)
None
None
0.16A100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		4ap5 GDP-FUCOSE PROTEIN
O-FUCOSYLTRANSFERASE
2
(Homo
sapiens)		3 / 3GLU A 232
TRP A 234
ASN A 116
None
1.05A19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		4d8p PEPTIDE FROM
GAMMA-GLIADIN,HLA
CLASS II
HISTOCOMPATIBILITY
ANTIGEN, DQ BETA 1
CHAIN
(Homo
sapiens;
Triticum
aestivum)		3 / 3GLU B 187
TRP B 188
ASN B 134
None
1.08A19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		4kxb GLUTAMYL
AMINOPEPTIDASE
(Homo
sapiens)		3 / 3GLU A 236
TRP A 133
ASN A  98
None
0.65A18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		4z0v 2',5'-PHOSPHODIESTER
ASE 12
(Homo
sapiens)		3 / 3GLU A 351
TRP A 459
ASN A 551
 MG  A 701 (-2.4A)
None
None
0.37A25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		5anb ELONGATION FACTOR TU
GTP-BINDING
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens)		3 / 3GLU K 802
TRP K 801
ASN K 818
None
1.06A16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_A_NMYA600_1
(BIFUNCTIONAL AAC/APH)		5lz6 3A
GOLGI RESIDENT
PROTEIN GCP60
(Aichivirus
B;
Homo
sapiens)		5 / 11SER B  13
ASP B  16
TYR A 525
SER A 393
GLU B  22
None
1.36A11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_A_NMYA600_1
(BIFUNCTIONAL AAC/APH)		5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens)		5 / 11ASP A  39
SER A  37
ASP A 199
TYR A 194
SER A 139
 ZN  A 501 (-2.0A)
None
ZN  A 502 (-2.3A)
None
None
1.17A19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_A_NMYA600_1
(BIFUNCTIONAL AAC/APH)		6bck N49P7 FAB HEAVY
CHAIN OF N29P7 IGG
N49P7 FAB LIGHT
CHAIN FROM N49P7 IGG
(Homo
sapiens)		5 / 11ASP H 144
SER H 120
GLU L 124
SER L 121
GLU L 160
None
1.45A9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_C_NMYC600_1
(BIFUNCTIONAL AAC/APH)		4rh7 GREEN FLUORESCENT
PROTEIN/CYTOPLASMIC
DYNEIN 2 HEAVY CHAIN
1
(Homo
sapiens;
synthetic
construct)		5 / 12SER A1536
ASP A1602
SER A1478
GLU A1480
GLU A1482
None
1.49A6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_C_NMYC600_1
(BIFUNCTIONAL AAC/APH)		5fhz ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3
(Homo
sapiens)		5 / 12ASP A 345
SER A  55
ASN A  53
ASP A 348
GLU A  58
None
1.13A19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_C_NMYC600_1
(BIFUNCTIONAL AAC/APH)		5lz6 3A
GOLGI RESIDENT
PROTEIN GCP60
(Aichivirus
B;
Homo
sapiens)		5 / 12SER B  13
ASP B  16
TYR A 525
SER A 393
GLU B  22
None
1.37A11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_C_NMYC600_1
(BIFUNCTIONAL AAC/APH)		5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens)		5 / 12ASP A  39
SER A  37
ASP A 199
TYR A 194
SER A 139
 ZN  A 501 (-2.0A)
None
ZN  A 502 (-2.3A)
None
None
1.18A19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_D_NMYD600_1
(BIFUNCTIONAL AAC/APH)		5lz6 3A
GOLGI RESIDENT
PROTEIN GCP60
(Aichivirus
B;
Homo
sapiens)		5 / 12SER B  13
ASP B  16
TYR A 525
SER A 393
GLU B  22
None
1.49A11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_D_NMYD600_1
(BIFUNCTIONAL AAC/APH)		5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens)		5 / 12ASP A  39
SER A  37
ASP A 199
TYR A 194
SER A 139
 ZN  A 501 (-2.0A)
None
ZN  A 502 (-2.3A)
None
None
1.19A19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		1pkr PLASMINOGEN
(Homo
sapiens)		5 / 11TYR A   9
ASP A  73
THR A  16
GLY A  60
ASP A  57
None
1.41A18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		1r47 ALPHA-GALACTOSIDASE
A
(Homo
sapiens)		5 / 11ASP A 136
ASN A 139
ASP A 175
GLY A 183
ASP A 182
None
NAG  A 639 (-1.9A)
NAG  A 639 ( 3.4A)
None
None
1.47A12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		2feb APOLIPOPROTEIN(A)
(Homo
sapiens)		5 / 11ASP A  17
THR A   9
HIS A   5
GLY A  36
ASP A  82
None
1.41A17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		4bkx METASTASIS-ASSOCIATE
D PROTEIN MTA1
HISTONE DEACETYLASE
1
(Homo
sapiens;
Homo
sapiens)		5 / 11TYR B  48
ASP B 332
HIS B  39
GLY B  17
GLU A 325
None
1.43A11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		4bvv APOLIPOPROTEIN(A)
(Homo
sapiens)		5 / 11TYR A   9
ASP A  73
THR A  16
GLY A  60
ASP A  57
SO4  A1082 (-4.7A)
None
None
None
CPF  A1081 (-3.9A)
1.35A16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		4duu PLASMINOGEN
(Homo
sapiens)		5 / 11TYR A  92
ASP A 155
THR A  99
GLY A 142
ASP A 139
None
1.41A7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		4duu PLASMINOGEN
(Homo
sapiens)		5 / 11TYR A 470
ASP A 534
THR A 477
GLY A 521
ASP A 518
None
1.33A7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		4uy4 SPINDLIN-4
(Homo
sapiens)		5 / 11TYR A 161
ASP A  82
TYR A 152
ASP A 169
HIS A 125
None
1.36A15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		4yj5 PYRUVATE KINASE PKM
(Homo
sapiens)		5 / 11ASP A 296
ASN A 273
ASP A 250
GLY A 116
ASP A 225
PYR  A 601 (-3.5A)
None
None
None
None
1.32A10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		5a1h SPINDLIN-3
(Homo
sapiens)		5 / 11TYR A 175
ASP A  91
TYR A 166
ASP A 183
HIS A 135
None
1.34A17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		5jz8 ASPARTYL/ASPARAGINYL
BETA-HYDROXYLASE
(Homo
sapiens)		5 / 11ASP A 720
HIS A 725
THR A 680
GLY A 681
GLU A 617
None
MN  A 801 ( 3.4A)
None
None
None
1.36A11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)		1pkr PLASMINOGEN
(Homo
sapiens)		5 / 10TYR A   9
ASP A  73
THR A  16
GLY A  60
ASP A  57
None
1.44A18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)		2feb APOLIPOPROTEIN(A)
(Homo
sapiens)		5 / 10ASP A  17
THR A   9
HIS A   5
GLY A  36
ASP A  82
None
1.41A17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)		4bkx METASTASIS-ASSOCIATE
D PROTEIN MTA1
HISTONE DEACETYLASE
1
(Homo
sapiens;
Homo
sapiens)		5 / 10ASP A 256
ASP B 332
HIS B  39
GLY B  17
GLU A 325
None
1.35A17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)		4bkx METASTASIS-ASSOCIATE
D PROTEIN MTA1
HISTONE DEACETYLASE
1
(Homo
sapiens;
Homo
sapiens)		5 / 10TYR B  48
ASP B 332
HIS B  39
GLY B  17
GLU A 325
None
1.47A11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)		4bvv APOLIPOPROTEIN(A)
(Homo
sapiens)		5 / 10TYR A   9
ASP A  73
THR A  16
GLY A  60
ASP A  57
SO4  A1082 (-4.7A)
None
None
None
CPF  A1081 (-3.9A)
1.38A16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)		4duu PLASMINOGEN
(Homo
sapiens)		5 / 10TYR A 470
ASP A 534
THR A 477
GLY A 521
ASP A 518
None
1.37A7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)		4obs ALPHA-L-IDURONIDASE
(Homo
sapiens)		5 / 10TYR A 258
ASP A 349
GLY A 222
ASP A 223
GLU A 182
None
1.18A10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)		5a1h SPINDLIN-3
(Homo
sapiens)		5 / 10TYR A 175
ASP A  91
TYR A 166
ASP A 183
HIS A 135
None
1.38A17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		2feb APOLIPOPROTEIN(A)
(Homo
sapiens)		5 / 10ASP A  17
THR A   9
HIS A   5
GLY A  36
ASP A  82
None
1.41A17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		2ggz GUANYLYL
CYCLASE-ACTIVATING
PROTEIN 3
(Homo
sapiens)		5 / 10ASP A  57
THR A  62
GLY A  69
ASP A  68
GLU A  75
None
None
None
CA  A 500 (-2.4A)
CA  A 500 (-2.0A)
1.35A17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		4bkx METASTASIS-ASSOCIATE
D PROTEIN MTA1
HISTONE DEACETYLASE
1
(Homo
sapiens;
Homo
sapiens)		5 / 10ASP A 256
ASP B 332
HIS B  39
GLY B  17
GLU A 325
None
1.31A17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		4bkx METASTASIS-ASSOCIATE
D PROTEIN MTA1
HISTONE DEACETYLASE
1
(Homo
sapiens;
Homo
sapiens)		5 / 10TYR B  48
ASP B 332
HIS B  39
GLY B  17
GLU A 325
None
1.41A11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		4bvv APOLIPOPROTEIN(A)
(Homo
sapiens)		5 / 10TYR A   9
ASP A  73
THR A  16
GLY A  60
ASP A  57
SO4  A1082 (-4.7A)
None
None
None
CPF  A1081 (-3.9A)
1.38A16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		4duu PLASMINOGEN
(Homo
sapiens)		5 / 10TYR A  92
ASP A 155
THR A  99
GLY A 142
ASP A 139
None
1.45A7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		4duu PLASMINOGEN
(Homo
sapiens)		5 / 10TYR A 470
ASP A 534
THR A 477
GLY A 521
ASP A 518
None
1.37A7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		4uy4 SPINDLIN-4
(Homo
sapiens)		5 / 10TYR A 161
ASP A  82
TYR A 152
ASP A 169
HIS A 125
None
1.37A15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		5a1h SPINDLIN-3
(Homo
sapiens)		5 / 10TYR A 175
ASP A  91
TYR A 166
ASP A 183
HIS A 135
None
1.36A17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		2feb APOLIPOPROTEIN(A)
(Homo
sapiens)		5 / 10ASP A  17
THR A   9
HIS A   5
GLY A  36
ASP A  82
None
1.42A17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		2ggz GUANYLYL
CYCLASE-ACTIVATING
PROTEIN 3
(Homo
sapiens)		5 / 10ASP A  57
THR A  62
GLY A  69
ASP A  68
GLU A  75
None
None
None
CA  A 500 (-2.4A)
CA  A 500 (-2.0A)
1.31A17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		4bkx METASTASIS-ASSOCIATE
D PROTEIN MTA1
HISTONE DEACETYLASE
1
(Homo
sapiens;
Homo
sapiens)		5 / 10ASP A 256
ASP B 332
HIS B  39
GLY B  17
GLU A 325
None
1.32A17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		4bkx METASTASIS-ASSOCIATE
D PROTEIN MTA1
HISTONE DEACETYLASE
1
(Homo
sapiens;
Homo
sapiens)		5 / 10TYR B  48
ASP B 332
HIS B  39
GLY B  17
GLU A 325
None
1.37A11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		4bvv APOLIPOPROTEIN(A)
(Homo
sapiens)		5 / 10TYR A   9
ASP A  73
THR A  16
GLY A  60
ASP A  57
SO4  A1082 (-4.7A)
None
None
None
CPF  A1081 (-3.9A)
1.39A16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		4duu PLASMINOGEN
(Homo
sapiens)		5 / 10TYR A  92
ASP A 155
THR A  99
GLY A 142
ASP A 139
None
1.45A7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		4duu PLASMINOGEN
(Homo
sapiens)		5 / 10TYR A 470
ASP A 534
THR A 477
GLY A 521
ASP A 518
None
1.38A7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		5a1h SPINDLIN-3
(Homo
sapiens)		5 / 10TYR A 175
ASP A  91
TYR A 166
ASP A 183
HIS A 135
None
1.38A17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		1pkr PLASMINOGEN
(Homo
sapiens)		5 / 10TYR A   9
ASP A  73
THR A  16
GLY A  60
ASP A  57
None
1.45A18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		2doi ANGIOSTATIN
(Homo
sapiens)		5 / 10TYR X  92
ASP X 155
THR X  99
GLY X 142
ASP X 139
None
1.50A16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		2feb APOLIPOPROTEIN(A)
(Homo
sapiens)		5 / 10ASP A  17
THR A   9
HIS A   5
GLY A  36
ASP A  82
None
1.42A17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens)		5 / 10TYR A1438
TYR A1242
THR A1238
GLY A1291
GLU A1367
None
1.27A10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		4bvv APOLIPOPROTEIN(A)
(Homo
sapiens)		5 / 10TYR A   9
ASP A  73
THR A  16
GLY A  60
ASP A  57
SO4  A1082 (-4.7A)
None
None
None
CPF  A1081 (-3.9A)
1.40A16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		4duu PLASMINOGEN
(Homo
sapiens)		5 / 10TYR A  92
ASP A 155
THR A  99
GLY A 142
ASP A 139
None
1.49A7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		4duu PLASMINOGEN
(Homo
sapiens)		5 / 10TYR A 470
ASP A 534
THR A 477
GLY A 521
ASP A 518
None
1.40A7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		4ui9 CELL DIVISION CYCLE
PROTEIN 23 HOMOLOG
(Homo
sapiens)		5 / 10TYR C 364
ASP C 301
THR C 369
GLY C 338
GLU C 374
None
1.45A11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		5a1h SPINDLIN-3
(Homo
sapiens)		5 / 10TYR A 175
ASP A  91
TYR A 166
ASP A 183
HIS A 135
None
1.38A17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		5hpg PLASMINOGEN
(Homo
sapiens)		5 / 10TYR A   9
ASP A  73
THR A  16
GLY A  60
ASP A  57
None
1.48A17.78