POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.


DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1ism BONE MARROW STROMAL
CELL ANTIGEN 1
(Homo
sapiens)
5 / 12ALA A  20
ARG A  23
ILE A  38
ASP A  34
PHE A  15
None
1.25A21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1jhw MACROPHAGE CAPPING
PROTEIN
(Homo
sapiens)
5 / 12ALA A 266
VAL A 265
GLN A 332
ILE A 277
PHE A 282
None
1.20A20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2jdx PROTEIN
(L-ARGININE:GLYCINE
AMIDINOTRANSFERASE)
(Homo
sapiens)
5 / 12ALA A 261
THR A 307
PHE A 296
ILE A 294
PHE A 308
None
1.19A20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2nz1 SMALL INDUCIBLE
CYTOKINE A2
(Homo
sapiens)
5 / 12ALA D  53
VAL D  41
ILE D  64
LYS D  58
TRP D  59
None
1.25A11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2q9g CYTOCHROME P450 46A1
(Homo
sapiens)
5 / 12THR A 298
PHE A 299
ILE A 141
ASP A 142
TRP A 134
None
HEM  A 505 (-4.0A)
None
None
HEM  A 505 (-3.7A)
1.19A23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
3ud2 ANKYRIN-1
(Homo
sapiens)
5 / 12ALA C 945
PRO C 946
THR C1057
ILE C 938
PHE C 985
None
1.30A23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4aej COLLAGEN
ALPHA-1(III) CHAIN
(Homo
sapiens)
5 / 12ALA A  84
VAL A 239
PHE A 235
ILE A 223
ASP A 222
None
1.30A21.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
8 / 12ALA A  18
VAL A  22
GLN A 232
THR A 240
PHE A 242
ARG A 260
ILE A 263
PHE A 366
None
1.04A61.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4l6e E3 SUMO-PROTEIN
LIGASE RANBP2
(Homo
sapiens)
5 / 12ALA A2938
VAL A3022
THR A3036
ILE A2971
PHE A3033
None
1.10A18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4p22 UBIQUITIN-LIKE
MODIFIER-ACTIVATING
ENZYME 1
(Homo
sapiens)
5 / 12VAL A 248
THR A 274
ILE A 277
ASP A  51
PHE A 275
None
1.27A22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4uom FAB FRAGMENT HEAVY
CHAIN
FAB FRAGMENT LIGHT
CHAIN
(Homo
sapiens)
5 / 12VAL L  59
THR H 101
ARG L  55
ILE L  49
ASP L  53
None
1.31A21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5h64 SERINE/THREONINE-PRO
TEIN KINASE MTOR
(Homo
sapiens)
5 / 12PRO A1116
VAL A1119
GLN A1183
ARG A1154
ILE A1155
None
1.11A9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
6bf6 INSULIN-DEGRADING
ENZYME
(Homo
sapiens)
5 / 12PRO A 837
GLN A 770
PHE A1005
ARG A 839
ILE A 843
None
1.16A13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1hi2 EOSINOPHIL-DERIVED
NEUROTOXIN
(Homo
sapiens)
5 / 12THR A  42
ILE A  30
ASN A  31
PHE A  43
HIS A  82
None
1.43A15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2bo9 HUMAN LATEXIN
(Homo
sapiens)
5 / 12VAL B  58
PHE B  89
ILE B  21
ASN B  22
PHE B  91
None
1.33A19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2gf9 RAS-RELATED PROTEIN
RAB-3D
(Homo
sapiens)
5 / 12VAL A 180
ARG A  66
ILE A  71
SER A  19
PHE A  23
None
1.42A20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2nvu MALTOSE BINDING
PROTEIN/NEDD8-ACTIVA
TING ENZYME E1
CATALYTIC SUBUNIT
CHIMERA
NEDD8-CONJUGATING
ENZYME UBC12
(Homo
sapiens)
5 / 12SER B2396
PHE C  80
ILE C 125
ASN C 126
PHE C  60
None
1.39A17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2r0b SERINE/THREONINE/TYR
OSINE-INTERACTING
PROTEIN
(Homo
sapiens)
5 / 12THR A 102
PHE A 130
ILE A  95
ASN A  94
PHE A  99
None
1.28A18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4a2y EOSINOPHIL CATIONIC
PROTEIN
(Homo
sapiens)
5 / 12THR A  42
ILE A  30
ASN A  31
PHE A  43
HIS A  82
None
1.47A14.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
5 / 12GLN A 232
PHE A 242
ASN A 264
SER A 267
HIS A 368
None
1.17A96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
5 / 12GLN A 232
THR A 240
PHE A 242
ASN A 264
SER A 267
None
0.85A96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
5 / 12SER A  19
VAL A  22
GLN A 232
ARG A 260
PHE A 366
None
1.10A96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
7 / 12VAL A  22
GLN A 232
PHE A 242
ILE A 263
ASN A 264
PHE A 366
HIS A 368
None
0.96A96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
7 / 12VAL A  22
GLN A 232
THR A 240
PHE A 242
ARG A 260
ILE A 263
PHE A 366
None
1.13A96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
7 / 12VAL A  22
GLN A 232
THR A 240
PHE A 242
ILE A 263
ASN A 264
PHE A 366
None
0.67A96.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4e93 TYROSINE-PROTEIN
KINASE FES/FPS
(Homo
sapiens)
5 / 12SER A 494
VAL A 495
GLN A 535
THR A 533
HIS A 529
None
1.22A21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4nen INTEGRIN ALPHA-X
(Homo
sapiens)
5 / 12SER A 767
VAL A 786
THR A 842
PHE A 802
HIS A 804
None
1.35A16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5d2n C25 BETA
(Homo
sapiens)
5 / 12SER F   7
GLN F  54
THR F  47
PHE F  49
ARG F  22
None
1.02A24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5e13 NON-SECRETORY
RIBONUCLEASE
(Homo
sapiens)
5 / 12THR A  42
ILE A  30
ASN A  31
PHE A  43
HIS A  82
None
1.44A16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5erd DESMOGLEIN-2
(Homo
sapiens)
5 / 12SER A 148
GLN A 112
PHE A 115
ILE A 132
PHE A 110
None
1.32A20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens)
5 / 12SER A 746
VAL A 452
ILE A 479
SER A 489
PHE A 471
None
None
None
UNX  A 920 ( 4.4A)
None
1.33A21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5wt7 PERIOSTIN
(Homo
sapiens)
5 / 12VAL A 112
GLN A  97
ILE A 101
SER A  99
PHE A  42
None
1.41A13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
6bf6 INSULIN-DEGRADING
ENZYME
(Homo
sapiens)
5 / 12GLN A 770
PHE A1005
ARG A 839
ILE A 843
HIS A 952
None
1.32A13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
6fyh E3 UBIQUITIN-PROTEIN
LIGASE HUWE1
(Homo
sapiens)
5 / 12SER A 315
VAL A 317
THR A 277
ILE A 268
PHE A 322
None
1.39A12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1hi2 EOSINOPHIL-DERIVED
NEUROTOXIN
(Homo
sapiens)
5 / 12THR A  42
ILE A  30
ASN A  31
PHE A  43
HIS A  82
None
1.35A15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2nvu MALTOSE BINDING
PROTEIN/NEDD8-ACTIVA
TING ENZYME E1
CATALYTIC SUBUNIT
CHIMERA
NEDD8-CONJUGATING
ENZYME UBC12
(Homo
sapiens)
5 / 12SER B2396
PHE C  80
ILE C 125
ASN C 126
PHE C  60
None
1.28A17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2r0b SERINE/THREONINE/TYR
OSINE-INTERACTING
PROTEIN
(Homo
sapiens)
5 / 12THR A 102
PHE A 130
ILE A  95
ASN A  94
PHE A  99
None
1.15A18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
3dwb ENDOTHELIN-CONVERTIN
G ENZYME 1
(Homo
sapiens)
5 / 12SER A 634
THR A 610
PHE A 475
SER A 478
PHE A 613
None
1.42A20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
3fed GLUTAMATE
CARBOXYPEPTIDASE III
(Homo
sapiens)
5 / 12THR A 379
ILE A  86
SER A 410
PHE A  67
HIS A  72
None
1.28A21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
3llr DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3A
(Homo
sapiens)
5 / 12SER A 103
PHE A  80
ILE A 133
ASN A 129
PHE A  76
None
1.40A18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
3wlw ANTIBODY L CHAIN
(Homo
sapiens)
5 / 12SER L  11
VAL L  10
PHE L  64
ILE L  77
HIS L  41
None
1.33A19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4a2y EOSINOPHIL CATIONIC
PROTEIN
(Homo
sapiens)
5 / 12THR A  42
ILE A  30
ASN A  31
PHE A  43
HIS A  82
None
1.39A14.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
7 / 12SER A  19
VAL A  22
GLN A 232
PHE A 242
ARG A 260
ILE A 263
PHE A 366
None
1.04A96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
8 / 12VAL A  22
GLN A 232
THR A 240
PHE A 242
ARG A 260
ILE A 263
SER A 267
PHE A 366
None
0.98A96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
8 / 12VAL A  22
GLN A 232
THR A 240
PHE A 242
ILE A 263
ASN A 264
PHE A 366
HIS A 368
None
0.83A96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
8 / 12VAL A  22
GLN A 232
THR A 240
PHE A 242
ILE A 263
ASN A 264
SER A 267
PHE A 366
None
0.63A96.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4nen INTEGRIN ALPHA-X
(Homo
sapiens)
5 / 12SER A 767
VAL A 786
THR A 842
PHE A 802
HIS A 804
None
1.26A16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4nik SINGLE-CHAIN FV
FRAGMENT ANTIBODY
(Homo
sapiens)
5 / 12SER B 145
VAL B 144
PHE B 198
ILE B 211
HIS B 175
None
1.45A22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4rh7 GREEN FLUORESCENT
PROTEIN/CYTOPLASMIC
DYNEIN 2 HEAVY CHAIN
1
(Homo
sapiens;
synthetic
construct)
5 / 12SER A1842
THR A1906
PHE A1918
ILE A1848
SER A1852
None
1.25A8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4wgk NEUTRAL CERAMIDASE
(Homo
sapiens)
5 / 12VAL A 314
GLN A 218
ILE A 118
SER A 216
HIS A 222
None
1.40A22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5drz HIV ANTIBODY F240
HEAVY CHAIN
HIV ANTIBODY F240
LIGHT CHAIN
(Homo
sapiens)
5 / 12PHE H 100
ARG H  38
ILE H  37
SER H  35
PHE L  98
None
1.42A21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5e13 NON-SECRETORY
RIBONUCLEASE
(Homo
sapiens)
5 / 12THR A  42
ILE A  30
ASN A  31
PHE A  43
HIS A  82
None
1.36A16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5h9p GALECTIN-3
(Homo
sapiens)
5 / 12PHE A 192
ARG A 144
ILE A 145
ASN A 160
PHE A 163
None
TD2  A 301 (-3.5A)
None
TD2  A 301 (-4.0A)
None
1.45A17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5hdh TOLL-LIKE RECEPTOR 8
(Homo
sapiens)
5 / 12SER A 152
PHE A  83
ILE A  92
ASN A  93
PHE A 121
None
1.44A20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
6bf6 INSULIN-DEGRADING
ENZYME
(Homo
sapiens)
5 / 12GLN A 770
PHE A1005
ARG A 839
ILE A 843
HIS A 952
None
1.22A13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1p1v SUPEROXIDE DISMUTASE
[CU-ZN]
(Homo
sapiens)
5 / 12ALA A  95
SER A  34
VAL A  97
PHE A  45
HIS A 120
None
None
None
None
ZN  A 201 ( 3.2A)
1.11A16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1z5v TUBULIN GAMMA-1
CHAIN
(Homo
sapiens)
5 / 12SER A 140
VAL A 171
GLN A 230
ILE A 228
SER A 226
GSP  A2466 (-3.1A)
None
None
GSP  A2466 (-4.5A)
None
1.28A21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2a2a DEATH-ASSOCIATED
PROTEIN KINASE 2
(Homo
sapiens)
5 / 12ALA A  25
SER A  21
VAL A  27
ILE A 160
ASN A 144
None
None
None
GOL  A3001 ( 3.9A)
None
0.98A21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2bo9 HUMAN LATEXIN
(Homo
sapiens)
5 / 12VAL B  58
PHE B  89
ILE B  21
ASN B  22
PHE B  91
None
1.23A18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2jdx PROTEIN
(L-ARGININE:GLYCINE
AMIDINOTRANSFERASE)
(Homo
sapiens)
5 / 12ALA A 261
THR A 307
PHE A 296
ILE A 294
PHE A 308
None
1.16A23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2r0b SERINE/THREONINE/TYR
OSINE-INTERACTING
PROTEIN
(Homo
sapiens)
5 / 12THR A 102
PHE A 130
ILE A  95
ASN A  94
PHE A  99
None
1.27A18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2v9k UNCHARACTERIZED
PROTEIN FLJ32312
(Homo
sapiens)
5 / 12ALA A 416
SER A 415
THR A 497
ILE A 461
PHE A 489
None
1.15A20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2w4k DEATH-ASSOCIATED
PROTEIN KINASE 1
(Homo
sapiens)
5 / 12ALA A  25
SER A  21
VAL A  27
ILE A 160
ASN A 144
ADP  A1303 ( 3.7A)
None
ADP  A1303 (-4.0A)
ADP  A1303 ( 4.1A)
MG  A1304 ( 4.2A)
1.08A22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
3llr DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3A
(Homo
sapiens)
6 / 12ALA A 102
SER A 103
PHE A  80
ILE A 133
ASN A 129
PHE A  76
None
1.49A18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
3lrh ANTI-HUNTINGTIN VL
DOMAIN
(Homo
sapiens)
5 / 12ALA A  12
SER A  11
VAL A 107
ILE A  20
SER A  73
None
1.25A15.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
5 / 12ALA A  18
SER A  19
VAL A  22
GLN A 232
PHE A 366
None
0.74A99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
7 / 12ALA A  18
VAL A  22
GLN A 232
PHE A 242
ILE A 263
PHE A 366
HIS A 368
None
1.01A99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
8 / 12ALA A  18
VAL A  22
GLN A 232
THR A 240
PHE A 242
ILE A 263
ASN A 264
PHE A 366
None
0.70A99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
5 / 12GLN A 232
THR A 240
PHE A 242
ASN A 264
SER A 267
None
0.96A99.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4cnt DIHYDROPYRIMIDINASE-
LIKE 3
(Homo
sapiens)
5 / 12SER A 385
GLN A 196
THR A 253
ILE A 391
HIS A  73
None
1.25A19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4e93 TYROSINE-PROTEIN
KINASE FES/FPS
(Homo
sapiens)
5 / 12SER A 494
VAL A 495
GLN A 535
THR A 533
HIS A 529
None
1.18A21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4gaf EBI-005
(Homo
sapiens)
5 / 12ALA A  58
SER A  44
PHE A 146
ILE A  10
PHE A 111
None
1.11A18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5aul PHOSPHATIDYLINOSITOL
3-KINASE REGULATORY
SUBUNIT ALPHA
(Homo
sapiens)
5 / 12SER A 660
VAL A 661
GLN A 705
THR A 701
HIS A 697
None
1.21A17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5c6w PROTEIN
IGHV1-69-2,IG LAMBDA
CHAIN V-II REGION
NIG-84
(Homo
sapiens)
5 / 12ALA H1012
SER H1011
VAL H1107
ILE H1020
SER H1074
None
1.07A20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5erd DESMOGLEIN-2
(Homo
sapiens)
5 / 12SER A 148
GLN A 112
PHE A 115
ILE A 132
PHE A 110
None
1.18A21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5j0g OXIDOREDUCTASE,SUPER
OXIDE DISMUTASE
[CU-ZN]
(Homo
sapiens)
5 / 12ALA A  83
SER A  52
VAL A  85
PHE A  63
HIS A 108
None
1.31A16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5j5j DESMOCOLLIN-2,DESMOG
LEIN-2
(Homo
sapiens)
5 / 12SER A 146
GLN A 110
PHE A 113
ILE A 130
PHE A 108
None
1.18A19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens)
5 / 12SER A 746
VAL A 452
ILE A 479
SER A 489
PHE A 471
None
None
None
UNX  A 920 ( 4.4A)
None
1.12A22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1hfh FACTOR H, 15TH AND
16TH C-MODULE PAIR
(Homo
sapiens)
5 / 12THR A  30
ARG A  20
ILE A  16
ASN A  17
SER A  33
None
1.42A15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1hi2 EOSINOPHIL-DERIVED
NEUROTOXIN
(Homo
sapiens)
5 / 12THR A  42
ILE A  30
ASN A  31
PHE A  43
HIS A  82
None
1.38A15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1z5v TUBULIN GAMMA-1
CHAIN
(Homo
sapiens)
5 / 12SER A 140
VAL A 171
GLN A 230
ILE A 228
SER A 226
GSP  A2466 (-3.1A)
None
None
GSP  A2466 (-4.5A)
None
1.28A21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2bo9 HUMAN LATEXIN
(Homo
sapiens)
5 / 12VAL B  58
PHE B  89
ILE B  21
ASN B  22
PHE B  91
None
1.38A18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2nvu MALTOSE BINDING
PROTEIN/NEDD8-ACTIVA
TING ENZYME E1
CATALYTIC SUBUNIT
CHIMERA
NEDD8-CONJUGATING
ENZYME UBC12
(Homo
sapiens)
5 / 12SER B2396
PHE C  80
ILE C 125
ASN C 126
PHE C  60
None
1.31A18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2r0b SERINE/THREONINE/TYR
OSINE-INTERACTING
PROTEIN
(Homo
sapiens)
5 / 12THR A 102
PHE A 130
ILE A  95
ASN A  94
PHE A  99
None
1.29A18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
3ibj CGMP-DEPENDENT
3',5'-CYCLIC
PHOSPHODIESTERASE
(Homo
sapiens)
5 / 12SER A 541
THR A 405
SER A 551
PHE A 404
HIS A 406
None
1.45A19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
3wlw ANTIBODY L CHAIN
(Homo
sapiens)
5 / 12SER L  11
VAL L  10
PHE L  64
ILE L  77
HIS L  41
None
1.39A19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4a2y EOSINOPHIL CATIONIC
PROTEIN
(Homo
sapiens)
5 / 12THR A  42
ILE A  30
ASN A  31
PHE A  43
HIS A  82
None
1.44A15.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
5 / 12GLN A 232
THR A 240
PHE A 242
ASN A 264
SER A 267
None
0.90A99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
5 / 12SER A  19
VAL A  22
GLN A 232
PHE A 242
PHE A 366
None
0.72A99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
6 / 12VAL A  22
GLN A 232
PHE A 242
ILE A 263
PHE A 366
HIS A 368
None
1.11A99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
7 / 12VAL A  22
GLN A 232
THR A 240
PHE A 242
ILE A 263
ASN A 264
PHE A 366
None
0.72A99.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5e13 NON-SECRETORY
RIBONUCLEASE
(Homo
sapiens)
5 / 12THR A  42
ILE A  30
ASN A  31
PHE A  43
HIS A  82
None
1.40A17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens)
5 / 12SER A 385
GLN A 196
THR A 253
ILE A 391
HIS A  73
SER  A 385 ( 0.0A)
GLN  A 196 ( 0.6A)
THR  A 253 ( 0.8A)
ILE  A 391 ( 0.6A)
HIS  A  73 ( 1.0A)
1.33A22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1z5v TUBULIN GAMMA-1
CHAIN
(Homo
sapiens)
5 / 12SER A 140
VAL A 171
GLN A 230
ILE A 228
SER A 226
GSP  A2466 (-3.1A)
None
None
GSP  A2466 (-4.5A)
None
1.23A21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2akz GAMMA ENOLASE
(Homo
sapiens)
5 / 12VAL A 349
GLN A 408
THR A 378
ILE A 133
PHE A 379
None
1.19A22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2bo9 HUMAN LATEXIN
(Homo
sapiens)
5 / 12VAL B  58
PHE B  89
ILE B  21
ASN B  22
PHE B  91
None
1.35A18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2fv5 ADAM 17
(Homo
sapiens)
5 / 12VAL A 364
THR A 404
ILE A 458
SER A 454
HIS A 405
None
None
None
None
ZN  A   3 ( 3.2A)
1.26A22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2nvu MALTOSE BINDING
PROTEIN/NEDD8-ACTIVA
TING ENZYME E1
CATALYTIC SUBUNIT
CHIMERA
NEDD8-CONJUGATING
ENZYME UBC12
(Homo
sapiens)
5 / 12SER B2396
PHE C  80
ILE C 125
ASN C 126
PHE C  60
None
1.33A18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2pg6 CYTOCHROME P450 2A6
(Homo
sapiens)
5 / 12SER A 175
THR A 212
PHE A 107
ILE A 300
PHE A 209
None
1.47A21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2r0b SERINE/THREONINE/TYR
OSINE-INTERACTING
PROTEIN
(Homo
sapiens)
5 / 12THR A 102
PHE A 130
ILE A  95
ASN A  94
PHE A  99
None
1.24A18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
3llr DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3A
(Homo
sapiens)
5 / 12SER A 103
PHE A  80
ILE A 133
ASN A 129
PHE A  76
None
1.44A18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
3u1k POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE 1, MITOCHONDRIAL
(Homo
sapiens)
5 / 12VAL A 313
THR A 287
ASN A 540
PHE A 340
HIS A 288
None
1.42A21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
3vvw CALCIUM-BINDING AND
COILED-COIL
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens)
5 / 12VAL A  23
PHE A 107
ILE A  56
PHE A  25
HIS A  41
None
1.20A14.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
5 / 12GLN A 232
THR A 240
PHE A 242
ASN A 264
SER A 267
None
0.84A99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
5 / 12THR A 240
PHE A 242
ASN A 264
SER A 267
HIS A 368
None
1.03A99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
7 / 12VAL A  22
GLN A 232
THR A 240
PHE A 242
ILE A 263
ASN A 264
PHE A 366
None
0.67A99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
6 / 12VAL A  22
THR A 240
PHE A 242
ASN A 264
PHE A 366
HIS A 368
None
0.82A99.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5d2n C25 BETA
(Homo
sapiens)
5 / 12SER F   7
GLN F  54
THR F  47
PHE F  49
ARG F  22
None
1.01A23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5erd DESMOGLEIN-2
(Homo
sapiens)
5 / 12SER A 148
GLN A 112
PHE A 115
ILE A 132
PHE A 110
None
1.32A21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5hx6 RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 1
(Homo
sapiens)
5 / 12SER A  73
PHE A 278
ARG A  74
ILE A 123
HIS A 136
None
None
None
None
65U  A 301 (-3.3A)
1.46A21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5j5j DESMOCOLLIN-2,DESMOG
LEIN-2
(Homo
sapiens)
5 / 12SER A 146
GLN A 110
PHE A 113
ILE A 130
PHE A 108
None
1.35A19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5u03 CTP SYNTHASE 1
(Homo
sapiens)
5 / 12SER A  22
VAL A  23
GLN A 240
ILE A 178
PHE A 266
None
1.44A19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens)
5 / 12SER A 746
VAL A 452
ILE A 479
SER A 489
PHE A 471
None
None
None
UNX  A 920 ( 4.4A)
None
1.38A22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1itu RENAL DIPEPTIDASE
(Homo
sapiens)
5 / 12THR A 149
ARG A 229
ASN A 231
HIS A 152
TRP A 162
None
None
None
CIL  A 451 (-4.0A)
None
1.31A22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1lhu SEX HORMONE-BINDING
GLOBULIN
(Homo
sapiens)
5 / 12SER A 111
VAL A 112
ILE A  78
PHE A  67
HIS A  81
None
None
None
EST  A 301 (-4.0A)
None
1.11A18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1z5v TUBULIN GAMMA-1
CHAIN
(Homo
sapiens)
5 / 12SER A 140
VAL A 171
GLN A 230
ILE A 228
SER A 226
GSP  A2466 (-3.1A)
None
None
GSP  A2466 (-4.5A)
None
1.30A21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2akz GAMMA ENOLASE
(Homo
sapiens)
5 / 12VAL A 349
GLN A 408
THR A 378
ILE A 133
PHE A 379
None
1.22A22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
2nvu MALTOSE BINDING
PROTEIN/NEDD8-ACTIVA
TING ENZYME E1
CATALYTIC SUBUNIT
CHIMERA
NEDD8-CONJUGATING
ENZYME UBC12
(Homo
sapiens)
5 / 12SER B2396
PHE C  80
ILE C 125
ASN C 126
PHE C  60
None
1.39A18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
3lmk METABOTROPIC
GLUTAMATE RECEPTOR 5
(Homo
sapiens)
5 / 12SER A 215
VAL A 214
GLN A 198
SER A 304
PHE A 231
None
1.32A21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
3u1k POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE 1, MITOCHONDRIAL
(Homo
sapiens)
5 / 12VAL A 313
THR A 287
ASN A 540
PHE A 340
HIS A 288
None
1.42A21.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
6 / 12GLN A 232
THR A 240
PHE A 242
ASN A 264
SER A 267
PHE A 366
None
0.69A99.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
7 / 12VAL A  22
GLN A 232
THR A 240
PHE A 242
ILE A 263
ASN A 264
PHE A 366
None
0.71A99.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4fdj N-ACETYLGALACTOSAMIN
E-6-SULFATASE
(Homo
sapiens)
5 / 12VAL A 277
PHE A 216
ILE A 217
PHE A 226
HIS A 224
None
1.41A20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4kmh SUPPRESSOR OF FUSED
HOMOLOG
(Homo
sapiens)
5 / 12SER A 377
GLN A 432
ILE A 406
PHE A 408
HIS A 394
None
1.29A21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
4xib E3 UBIQUITIN-PROTEIN
LIGASE MIB1
(Homo
sapiens)
5 / 12VAL A  19
ARG A  20
ILE A 146
PHE A 226
HIS A 230
None
1.39A21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5k10 ISOCITRATE
DEHYDROGENASE [NADP]
CYTOPLASMIC
(Homo
sapiens)
5 / 12THR A 325
PHE A 395
ARG A  20
ILE A  21
HIS A 315
None
None
None
None
NDP  A 501 (-4.7A)
1.46A19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5nug CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens)
5 / 12VAL A2592
ILE A2666
ASN A2667
PHE A2727
HIS A2725
None
1.27A5.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5u03 CTP SYNTHASE 1
(Homo
sapiens)
5 / 12SER A  22
VAL A  23
GLN A 240
ILE A 178
PHE A 266
None
1.44A19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens)
5 / 12SER A 746
VAL A 452
ILE A 479
SER A 489
PHE A 471
None
None
None
UNX  A 920 ( 4.4A)
None
1.34A22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
1ufw SYNAPTOJANIN 2
(Homo
sapiens)
5 / 12MET A  42
LEU A  41
LEU A  22
ILE A  51
PHE A  65
None
1.35A17.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
6 / 12LEU A 704
ASN A 705
GLY A 708
GLN A 711
MET A 742
ARG A 752
BHM  A   1 (-4.0A)
BHM  A   1 (-3.6A)
BHM  A   1 ( 3.8A)
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
BHM  A   1 (-3.8A)
0.94A49.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
6 / 12LEU A 704
ASN A 705
GLY A 708
GLN A 711
MET A 742
PHE A 891
BHM  A   1 (-4.0A)
BHM  A   1 (-3.6A)
BHM  A   1 ( 3.8A)
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
None
0.93A49.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
5 / 12LEU A 704
GLN A 711
MET A 742
ARG A 752
GLN A 783
BHM  A   1 (-4.0A)
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
BHM  A   1 (-3.8A)
None
1.35A49.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
2g76 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
(Homo
sapiens)
5 / 12LEU A 216
ASN A 217
GLY A 214
LEU A 150
GLN A 223
None
1.36A21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
2z5x AMINE OXIDASE
[FLAVIN-CONTAINING]
A
(Homo
sapiens)
5 / 12GLY A  22
MET A 445
LEU A  80
GLN A 225
THR A  54
FAD  A 600 (-3.2A)
FAD  A 600 (-4.3A)
None
None
None
1.44A20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
3f81 DUAL SPECIFICITY
PROTEIN PHOSPHATASE
3
(Homo
sapiens)
5 / 12LEU A 177
ARG A 176
GLN A 143
THR A  34
ILE A  37
None
1.48A21.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)
5 / 12GLY A 722
GLN A 725
MET A 756
LEU A 763
ARG A 766
WOW  A   1 ( 4.3A)
WOW  A   1 ( 4.1A)
WOW  A   1 ( 4.1A)
WOW  A   1 ( 4.0A)
WOW  A   1 (-3.8A)
0.85A54.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)
8 / 12LEU A 718
ASN A 719
GLY A 722
MET A 756
LEU A 763
ARG A 766
THR A 894
PHE A 905
WOW  A   1 (-4.2A)
WOW  A   1 (-3.3A)
WOW  A   1 ( 4.3A)
WOW  A   1 ( 4.1A)
WOW  A   1 ( 4.0A)
WOW  A   1 (-3.8A)
WOW  A   1 (-3.9A)
WOW  A   1 (-4.6A)
0.75A54.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
4cak INTEGRIN ALPHA-IIB
INTEGRIN BETA-3
(Homo
sapiens)
5 / 12GLY B 293
LEU B 246
ARG A 317
GLN B 228
THR A 413
None
1.35A16.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
5 / 12ASN A 564
GLY A 567
LEU A 627
THR A 739
PHE A 749
MOF  A 801 (-3.0A)
MOF  A 801 (-3.4A)
None
MOF  A 801 (-3.9A)
MOF  A 801 (-4.4A)
1.44A98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
5 / 12ASN A 564
GLY A 568
MET A 601
ILE A 747
PHE A 749
MOF  A 801 (-3.0A)
None
MOF  A 801 (-3.7A)
MOF  A 801 ( 4.4A)
MOF  A 801 (-4.4A)
0.90A98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
11 / 12MET A 560
LEU A 563
ASN A 564
GLY A 567
GLN A 570
MET A 601
LEU A 608
ARG A 611
THR A 739
ILE A 747
PHE A 749
MOF  A 801 (-3.9A)
MOF  A 801 (-3.9A)
MOF  A 801 (-3.0A)
MOF  A 801 (-3.4A)
MOF  A 801 (-2.9A)
MOF  A 801 (-3.7A)
MOF  A 801 ( 4.6A)
MOF  A 801 (-4.2A)
MOF  A 801 (-3.9A)
MOF  A 801 ( 4.4A)
MOF  A 801 (-4.4A)
0.52A98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
5 / 12MET A 560
LEU A 563
LEU A 621
THR A 739
ILE A 747
MOF  A 801 (-3.9A)
MOF  A 801 (-3.9A)
None
MOF  A 801 (-3.9A)
MOF  A 801 ( 4.4A)
1.25A98.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
4u8d SORCIN
(Homo
sapiens)
5 / 12LEU A  58
GLY A  62
LEU A  35
ILE A 160
PHE A 156
None
1.24A20.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
8 / 12LEU A 769
ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
THR A 945
PHE A 956
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
0.47A54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
5 / 12ASN A 770
GLY A 774
GLN A 776
THR A 945
PHE A 956
ECV  A1101 (-3.1A)
None
ECV  A1101 (-2.9A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
1.24A45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
8 / 12LEU A 769
ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
THR A 945
PHE A 956
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
0.56A45.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
5n6c D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
(Homo
sapiens)
5 / 12LEU A 217
ASN A 218
GLY A 215
LEU A 151
GLN A 224
None
1.39A16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
5nzp D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
(Homo
sapiens)
5 / 12LEU B 217
ASN B 218
GLY B 215
LEU B 151
GLN B 224
None
None
None
9EW  B 301 ( 4.8A)
None
1.25A22.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
5toa ESTROGEN RECEPTOR
BETA
(Homo
sapiens)
5 / 12MET A 295
LEU A 298
MET A 336
LEU A 343
ARG A 346
EST  A 601 ( 4.4A)
EST  A 601 (-4.1A)
EST  A 601 ( 3.7A)
EST  A 601 ( 4.4A)
EST  A 601 (-4.1A)
0.98A30.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens)
5 / 12GLN C1023
LEU A 266
THR A 220
ILE A 226
PHE A 232
None
1.43A13.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_C_HCYC900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
5 / 11ASN A 705
LEU A 707
GLN A 711
MET A 742
ARG A 752
BHM  A   1 (-3.6A)
BHM  A   1 ( 4.2A)
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
BHM  A   1 (-3.8A)
0.75A49.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_C_HCYC900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
5 / 11ASN A 705
LEU A 707
GLN A 711
MET A 745
ARG A 752
BHM  A   1 (-3.6A)
BHM  A   1 ( 4.2A)
BHM  A   1 (-2.2A)
BHM  A   1 (-3.9A)
BHM  A   1 (-3.8A)
1.02A49.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_C_HCYC900_1
(GLUCOCORTICOID
RECEPTOR)
3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)
5 / 11ASN A 719
LEU A 721
MET A 756
ARG A 766
THR A 894
WOW  A   1 (-3.3A)
WOW  A   1 ( 4.3A)
WOW  A   1 ( 4.1A)
WOW  A   1 (-3.8A)
WOW  A   1 (-3.9A)
0.73A54.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_C_HCYC900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
10 / 11MET A 560
ASN A 564
LEU A 566
GLN A 570
TRP A 600
MET A 601
MET A 604
ARG A 611
THR A 739
ILE A 747
MOF  A 801 (-3.9A)
MOF  A 801 (-3.0A)
MOF  A 801 ( 4.6A)
MOF  A 801 (-2.9A)
None
MOF  A 801 (-3.7A)
None
MOF  A 801 (-4.2A)
MOF  A 801 (-3.9A)
MOF  A 801 ( 4.4A)
0.41A98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_C_HCYC900_1
(GLUCOCORTICOID
RECEPTOR)
4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
7 / 11ASN A 770
LEU A 772
GLN A 776
TRP A 806
MET A 807
ARG A 817
THR A 945
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.5A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 (-3.1A)
0.39A54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_C_HCYC900_1
(GLUCOCORTICOID
RECEPTOR)
5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
7 / 11ASN A 770
LEU A 772
GLN A 776
TRP A 806
MET A 807
ARG A 817
THR A 945
ECV  A1101 (-3.1A)
ECV  A1101 ( 3.9A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
0.41A45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_C_HCYC900_1
(GLUCOCORTICOID
RECEPTOR)
5toa ESTROGEN RECEPTOR
BETA
(Homo
sapiens)
5 / 11MET A 295
LEU A 301
TRP A 335
MET A 336
ARG A 346
EST  A 601 ( 4.4A)
EST  A 601 ( 4.3A)
None
EST  A 601 ( 3.7A)
EST  A 601 (-4.1A)
0.75A30.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
7 / 12LEU A 704
ASN A 705
GLY A 708
GLN A 711
MET A 742
ARG A 752
PHE A 891
BHM  A   1 (-4.0A)
BHM  A   1 (-3.6A)
BHM  A   1 ( 3.8A)
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
BHM  A   1 (-3.8A)
None
0.96A49.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
6 / 12LEU A 704
ASN A 705
GLY A 708
GLN A 711
MET A 745
ARG A 752
BHM  A   1 (-4.0A)
BHM  A   1 (-3.6A)
BHM  A   1 ( 3.8A)
BHM  A   1 (-2.2A)
BHM  A   1 (-3.9A)
BHM  A   1 (-3.8A)
1.02A49.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
5 / 12LEU A 704
GLN A 711
MET A 742
ARG A 752
GLN A 783
BHM  A   1 (-4.0A)
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
BHM  A   1 (-3.8A)
None
1.38A49.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
5 / 12LEU A 704
GLN A 711
MET A 745
ARG A 752
GLN A 783
BHM  A   1 (-4.0A)
BHM  A   1 (-2.2A)
BHM  A   1 (-3.9A)
BHM  A   1 (-3.8A)
None
1.37A49.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
2g76 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
(Homo
sapiens)
5 / 12LEU A 216
ASN A 217
GLY A 214
LEU A 150
GLN A 223
None
1.39A21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
3f81 DUAL SPECIFICITY
PROTEIN PHOSPHATASE
3
(Homo
sapiens)
5 / 12LEU A 177
ARG A 176
GLN A 143
THR A  34
ILE A  37
None
1.47A21.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)
5 / 12GLY A 722
GLN A 725
MET A 756
MET A 759
ARG A 766
WOW  A   1 ( 4.3A)
WOW  A   1 ( 4.1A)
WOW  A   1 ( 4.1A)
WOW  A   1 (-3.7A)
WOW  A   1 (-3.8A)
1.23A54.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)
6 / 12GLY A 722
MET A 756
MET A 759
LEU A 763
ARG A 766
PHE A 905
WOW  A   1 ( 4.3A)
WOW  A   1 ( 4.1A)
WOW  A   1 (-3.7A)
WOW  A   1 ( 4.0A)
WOW  A   1 (-3.8A)
WOW  A   1 (-4.6A)
0.94A54.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)
8 / 12LEU A 718
ASN A 719
GLY A 722
MET A 756
LEU A 763
ARG A 766
THR A 894
PHE A 905
WOW  A   1 (-4.2A)
WOW  A   1 (-3.3A)
WOW  A   1 ( 4.3A)
WOW  A   1 ( 4.1A)
WOW  A   1 ( 4.0A)
WOW  A   1 (-3.8A)
WOW  A   1 (-3.9A)
WOW  A   1 (-4.6A)
0.69A54.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
4cak INTEGRIN ALPHA-IIB
INTEGRIN BETA-3
(Homo
sapiens)
5 / 12GLY B 293
LEU B 246
ARG A 317
GLN B 228
THR A 413
None
1.34A16.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
5 / 12ASN A 564
GLY A 567
LEU A 627
THR A 739
PHE A 749
MOF  A 801 (-3.0A)
MOF  A 801 (-3.4A)
None
MOF  A 801 (-3.9A)
MOF  A 801 (-4.4A)
1.44A98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
6 / 12ASN A 564
GLY A 568
MET A 601
THR A 739
ILE A 747
PHE A 749
MOF  A 801 (-3.0A)
None
MOF  A 801 (-3.7A)
MOF  A 801 (-3.9A)
MOF  A 801 ( 4.4A)
MOF  A 801 (-4.4A)
0.97A98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
11 / 12LEU A 563
ASN A 564
GLY A 567
GLN A 570
MET A 601
MET A 604
LEU A 608
ARG A 611
THR A 739
ILE A 747
PHE A 749
MOF  A 801 (-3.9A)
MOF  A 801 (-3.0A)
MOF  A 801 (-3.4A)
MOF  A 801 (-2.9A)
MOF  A 801 (-3.7A)
None
MOF  A 801 ( 4.6A)
MOF  A 801 (-4.2A)
MOF  A 801 (-3.9A)
MOF  A 801 ( 4.4A)
MOF  A 801 (-4.4A)
0.39A98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
5 / 12LEU A 563
LEU A 621
THR A 739
ILE A 747
PHE A 749
MOF  A 801 (-3.9A)
None
MOF  A 801 (-3.9A)
MOF  A 801 ( 4.4A)
MOF  A 801 (-4.4A)
1.46A98.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
4u8d SORCIN
(Homo
sapiens)
5 / 12LEU A  58
GLY A  62
LEU A  35
ILE A 160
PHE A 156
None
1.29A20.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
8 / 12LEU A 769
ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
THR A 945
PHE A 956
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
0.38A54.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
4xny HEAVY CHAIN OF
ANTIBODY VRC08C
LIGHT CHAIN OF
ANTIBODY VRC08C
(Homo
sapiens)
5 / 12ASN H  35
GLN L  89
LEU L  46
GLN H   4
ILE H  34
None
1.40A19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens)
5 / 12LEU A1967
ASN A1964
GLY A1968
LEU A2026
ILE A1960
None
1.35A19.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
8 / 12LEU A 769
ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
THR A 945
PHE A 956
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
0.49A45.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
5n6c D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
(Homo
sapiens)
5 / 12LEU A 217
ASN A 218
GLY A 215
LEU A 151
GLN A 224
None
1.41A16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
5nzp D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
(Homo
sapiens)
5 / 12LEU B 217
ASN B 218
GLY B 215
LEU B 151
GLN B 224
None
None
None
9EW  B 301 ( 4.8A)
None
1.29A22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens)
5 / 12GLN C1023
LEU A 266
THR A 220
ILE A 226
PHE A 232
None
1.46A13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
1nxk MAP KINASE-ACTIVATED
PROTEIN KINASE 2
(Homo
sapiens)
5 / 12TRP A 324
LEU A 249
THR A 338
ILE A 150
PHE A 158
None
1.43A20.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
6 / 12ASN A 705
GLY A 708
GLN A 711
MET A 742
ARG A 752
PHE A 891
BHM  A   1 (-3.6A)
BHM  A   1 ( 3.8A)
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
BHM  A   1 (-3.8A)
None
0.86A49.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
5 / 12GLY A 708
GLN A 711
MET A 742
ARG A 752
MET A 787
BHM  A   1 ( 3.8A)
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
BHM  A   1 (-3.8A)
BHM  A   1 (-3.6A)
0.93A49.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
2rgz HEME OXYGENASE 2
(Homo
sapiens)
5 / 12MET A 158
LEU A  97
MET A 206
THR A  41
PHE A 227
None
None
None
None
HEM  A 300 (-4.1A)
1.46A22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
3f81 DUAL SPECIFICITY
PROTEIN PHOSPHATASE
3
(Homo
sapiens)
5 / 12LEU A 177
ARG A 176
GLN A 143
THR A  34
ILE A  37
None
1.49A21.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)
5 / 12ASN A 719
GLY A 722
LEU A 782
THR A 894
PHE A 905
WOW  A   1 (-3.3A)
WOW  A   1 ( 4.3A)
None
WOW  A   1 (-3.9A)
WOW  A   1 (-4.6A)
1.49A54.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)
8 / 12ASN A 719
GLY A 722
MET A 756
LEU A 763
ARG A 766
MET A 801
THR A 894
PHE A 905
WOW  A   1 (-3.3A)
WOW  A   1 ( 4.3A)
WOW  A   1 ( 4.1A)
WOW  A   1 ( 4.0A)
WOW  A   1 (-3.8A)
WOW  A   1 (-4.2A)
WOW  A   1 (-3.9A)
WOW  A   1 (-4.6A)
0.81A54.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)
7 / 12ASN A 719
TRP A 755
MET A 756
LEU A 763
MET A 801
THR A 894
PHE A 905
WOW  A   1 (-3.3A)
None
WOW  A   1 ( 4.1A)
WOW  A   1 ( 4.0A)
WOW  A   1 (-4.2A)
WOW  A   1 (-3.9A)
WOW  A   1 (-4.6A)
1.16A54.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)
6 / 12GLY A 722
GLN A 725
MET A 756
LEU A 763
ARG A 766
MET A 801
WOW  A   1 ( 4.3A)
WOW  A   1 ( 4.1A)
WOW  A   1 ( 4.1A)
WOW  A   1 ( 4.0A)
WOW  A   1 (-3.8A)
WOW  A   1 (-4.2A)
0.90A54.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
3kn5 RIBOSOMAL PROTEIN S6
KINASE ALPHA-5
(Homo
sapiens)
5 / 12TRP A 686
LEU A 608
THR A 700
ILE A 510
PHE A 516
None
1.40A22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
4cak INTEGRIN ALPHA-IIB
INTEGRIN BETA-3
(Homo
sapiens)
5 / 12GLY B 293
LEU B 246
ARG A 317
GLN B 228
THR A 413
None
1.34A16.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
11 / 12ASN A 564
GLY A 567
GLN A 570
TRP A 600
MET A 601
LEU A 608
ARG A 611
MET A 646
THR A 739
ILE A 747
PHE A 749
MOF  A 801 (-3.0A)
MOF  A 801 (-3.4A)
MOF  A 801 (-2.9A)
None
MOF  A 801 (-3.7A)
MOF  A 801 ( 4.6A)
MOF  A 801 (-4.2A)
MOF  A 801 (-4.4A)
MOF  A 801 (-3.9A)
MOF  A 801 ( 4.4A)
MOF  A 801 (-4.4A)
0.42A98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
5 / 12ASN A 564
GLY A 567
LEU A 627
THR A 739
PHE A 749
MOF  A 801 (-3.0A)
MOF  A 801 (-3.4A)
None
MOF  A 801 (-3.9A)
MOF  A 801 (-4.4A)
1.42A98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
7 / 12ASN A 564
GLY A 568
TRP A 600
MET A 601
THR A 739
ILE A 747
PHE A 749
MOF  A 801 (-3.0A)
None
None
MOF  A 801 (-3.7A)
MOF  A 801 (-3.9A)
MOF  A 801 ( 4.4A)
MOF  A 801 (-4.4A)
0.94A98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
5 / 12MET A 601
LEU A 608
ARG A 611
GLN A 642
MET A 646
MOF  A 801 (-3.7A)
MOF  A 801 ( 4.6A)
MOF  A 801 (-4.2A)
None
MOF  A 801 (-4.4A)
0.92A98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
8 / 12ASN A 770
GLN A 776
TRP A 806
MET A 807
LEU A 814
ARG A 817
MET A 852
THR A 945
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-3.1A)
0.66A54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
8 / 12ASN A 770
GLN A 776
TRP A 806
MET A 807
LEU A 814
ARG A 817
THR A 945
PHE A 956
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
0.36A54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
5 / 12ASN A 770
GLY A 774
TRP A 806
THR A 945
PHE A 956
CV7  A1987 (-3.1A)
None
None
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
1.09A54.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
5bo6 SIA-ALPHA-2,3-GAL-BE
TA-1,4-GLCNAC-R:ALPH
A
2,8-SIALYLTRANSFERAS
E
(Homo
sapiens)
5 / 12GLY A 302
LEU A 299
GLN A 100
THR A 372
ILE A 316
CDP  A 411 (-3.3A)
None
None
None
None
1.37A21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
5m23 WD REPEAT-CONTAINING
PROTEIN 5
(Homo
sapiens)
5 / 12GLY A 183
GLN A 140
LEU A 143
ILE A 197
PHE A 222
None
1.50A20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
8 / 12ASN A 770
GLN A 776
TRP A 806
MET A 807
LEU A 814
ARG A 817
THR A 945
PHE A 956
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
0.48A45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
5 / 12ASN A 770
GLY A 774
TRP A 806
THR A 945
PHE A 956
ECV  A1101 (-3.1A)
None
None
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
1.02A45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
6 / 12GLN A 776
TRP A 806
MET A 807
LEU A 814
ARG A 817
MET A 852
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
1.22A45.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
5yh3 EXTRACELLULAR
SERINE/THREONINE
PROTEIN KINASE
FAM20C
(Homo
sapiens)
5 / 12ASN C 479
GLY C 482
LEU C 546
ARG C 549
MET C 525
None
1.47A13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)
6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens)
5 / 12GLN C1023
LEU A 266
THR A 220
ILE A 226
PHE A 232
None
1.47A13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)
1bhg BETA-GLUCURONIDASE
(Homo
sapiens)
3 / 3LEU A 322
MET A 393
TYR A 301
None
0.70A16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)
1hkk CHITOTRIOSIDASE-1
(Homo
sapiens)
3 / 3LEU A 360
MET A 356
TYR A 303
None
AMI  A1388 (-4.0A)
None
0.96A20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)
1x9q 4M5.3
ANTI-FLUORESCEIN
SINGLE CHAIN
ANTIBODY FRAGMENT
(Homo
sapiens)
3 / 3LEU A 259
MET A 185
TYR A 247
None
0.75A18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)
2ch6 N-ACETYL-D-GLUCOSAMI
NE KINASE
(Homo
sapiens)
3 / 3LEU A 264
MET A 305
TYR A 341
None
0.77A19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)
2f5a PROTEIN (ANTIBODY
2F5 (HEAVY CHAIN))
PROTEIN (ANTIBODY
2F5 (LIGHT CHAIN))
(Homo
sapiens)
3 / 3LEU H  47
MET H 119
TYR L  86
None
0.95A20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)
2i6t UBIQUITIN-CONJUGATIN
G ENZYME E2-LIKE
ISOFORM A
(Homo
sapiens)
3 / 3LEU A 321
MET A 397
TYR A 328
GOL  A   6 (-3.8A)
None
None
0.85A22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)
3a62 RIBOSOMAL PROTEIN S6
KINASE BETA-1
(Homo
sapiens)
3 / 3LEU A 168
MET A 122
TYR A 102
None
0.90A20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)
3q13 SPONDIN-1
(Homo
sapiens)
3 / 3LEU A 350
MET A 320
TYR A 212
None
None
NAG  A 502 ( 3.8A)
0.93A21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)
4hjj ANTI-IL12 ANTI-IL18
DFAB HEAVY CHAIN
ANTI-IL12 ANTI-IL18
DFAB LIGHT CHAIN
(Homo
sapiens)
3 / 3LEU H  47
MET H 106
TYR L  86
None
0.96A20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)
5gje LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 6
(Homo
sapiens)
3 / 3LEU B 873
MET B 877
TYR B 846
None
0.81A17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)
5knm CDNA FLJ39643 FIS,
CLONE SMINT2004023,
HIGHLY SIMILAR TO
HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, ALPHACHAIN
F
(Homo
sapiens)
3 / 3LEU A   5
MET A  98
TYR A 159
None
0.73A22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)
5nr4 CLIP-ASSOCIATING
PROTEIN 2
(Homo
sapiens)
3 / 3LEU A  97
MET A 120
TYR A  89
None
0.88A14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)
5nr4 CLIP-ASSOCIATING
PROTEIN 2
(Homo
sapiens)
3 / 3LEU A 115
MET A 120
TYR A  89
None
0.85A14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)
5whr INDOLEAMINE
2,3-DIOXYGENASE 1
(Homo
sapiens)
3 / 3LEU A  83
MET A  40
TYR A  90
None
0.84A18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)
6bqh 5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562
(Escherichia
coli;
Homo
sapiens)
3 / 3LEU A 227
MET A 143
TYR A 234
None
OLC  A1207 ( 3.9A)
None
0.51A16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)
6cmj CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE KINASE 2
(Homo
sapiens)
3 / 3LEU A 263
MET A 193
TYR A 176
None
0.68A13.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
5 / 12GLN A 711
MET A 742
ARG A 752
GLN A 783
MET A 787
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
BHM  A   1 (-3.8A)
None
BHM  A   1 (-3.6A)
1.22A49.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
5 / 12GLY A 708
GLN A 711
MET A 742
ARG A 752
MET A 787
BHM  A   1 ( 3.8A)
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
BHM  A   1 (-3.8A)
BHM  A   1 (-3.6A)
0.93A49.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
6 / 12LEU A 704
ASN A 705
GLY A 708
GLN A 711
MET A 742
ARG A 752
BHM  A   1 (-4.0A)
BHM  A   1 (-3.6A)
BHM  A   1 ( 3.8A)
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
BHM  A   1 (-3.8A)
0.87A49.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
6 / 12LEU A 704
ASN A 705
GLY A 708
GLN A 711
MET A 742
PHE A 891
BHM  A   1 (-4.0A)
BHM  A   1 (-3.6A)
BHM  A   1 ( 3.8A)
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
None
0.92A49.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
5 / 12LEU A 704
GLN A 711
MET A 742
ARG A 752
GLN A 783
BHM  A   1 (-4.0A)
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
BHM  A   1 (-3.8A)
None
1.36A49.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
2g76 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
(Homo
sapiens)
5 / 12LEU A 216
ASN A 217
GLY A 214
LEU A 150
GLN A 223
None
1.40A21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
2rgz HEME OXYGENASE 2
(Homo
sapiens)
5 / 12MET A 158
LEU A  97
MET A 206
THR A  41
PHE A 227
None
None
None
None
HEM  A 300 (-4.1A)
1.47A22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
3d5f PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA
(Homo
sapiens)
5 / 12LEU A 417
LEU A 436
MET A 439
ILE A 218
PHE A 214
None
1.31A21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
3f81 DUAL SPECIFICITY
PROTEIN PHOSPHATASE
3
(Homo
sapiens)
5 / 12LEU A 177
ARG A 176
GLN A 143
THR A  34
ILE A  37
None
1.44A21.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)
6 / 12GLY A 722
GLN A 725
MET A 756
LEU A 763
ARG A 766
MET A 801
WOW  A   1 ( 4.3A)
WOW  A   1 ( 4.1A)
WOW  A   1 ( 4.1A)
WOW  A   1 ( 4.0A)
WOW  A   1 (-3.8A)
WOW  A   1 (-4.2A)
0.90A54.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)
9 / 12LEU A 718
ASN A 719
GLY A 722
MET A 756
LEU A 763
ARG A 766
MET A 801
THR A 894
PHE A 905
WOW  A   1 (-4.2A)
WOW  A   1 (-3.3A)
WOW  A   1 ( 4.3A)
WOW  A   1 ( 4.1A)
WOW  A   1 ( 4.0A)
WOW  A   1 (-3.8A)
WOW  A   1 (-4.2A)
WOW  A   1 (-3.9A)
WOW  A   1 (-4.6A)
0.81A54.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
3s5n 4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE,
MITOCHONDRIAL
(Homo
sapiens)
5 / 12LEU A 220
LEU A 107
MET A 134
ILE A 205
PHE A 226
None
1.41A20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
4cak INTEGRIN ALPHA-IIB
INTEGRIN BETA-3
(Homo
sapiens)
5 / 12GLY B 293
LEU B 246
ARG A 317
GLN B 228
THR A 413
None
1.32A16.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
5 / 12ASN A 564
GLY A 567
LEU A 627
THR A 739
PHE A 749
MOF  A 801 (-3.0A)
MOF  A 801 (-3.4A)
None
MOF  A 801 (-3.9A)
MOF  A 801 (-4.4A)
1.44A98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
7 / 12ASN A 564
GLY A 568
GLN A 570
MET A 601
THR A 739
ILE A 747
PHE A 749
MOF  A 801 (-3.0A)
None
MOF  A 801 (-2.9A)
MOF  A 801 (-3.7A)
MOF  A 801 (-3.9A)
MOF  A 801 ( 4.4A)
MOF  A 801 (-4.4A)
1.14A98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
11 / 12LEU A 563
ASN A 564
GLY A 567
GLN A 570
MET A 601
LEU A 608
ARG A 611
MET A 646
THR A 739
ILE A 747
PHE A 749
MOF  A 801 (-3.9A)
MOF  A 801 (-3.0A)
MOF  A 801 (-3.4A)
MOF  A 801 (-2.9A)
MOF  A 801 (-3.7A)
MOF  A 801 ( 4.6A)
MOF  A 801 (-4.2A)
MOF  A 801 (-4.4A)
MOF  A 801 (-3.9A)
MOF  A 801 ( 4.4A)
MOF  A 801 (-4.4A)
0.43A98.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
4u8d SORCIN
(Homo
sapiens)
5 / 12LEU A  58
GLY A  62
LEU A  35
ILE A 160
PHE A 156
None
1.27A20.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
5 / 12ASN A 770
GLY A 774
GLN A 776
THR A 945
PHE A 956
CV7  A1987 (-3.1A)
None
CV7  A1987 (-3.0A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
1.34A54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
9 / 12LEU A 769
ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
THR A 945
PHE A 956
CV7  A1987 (-4.1A)
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
CV7  A1987 ( 3.9A)
CV7  A1987 ( 4.0A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
0.67A54.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
4wmh HEME OXYGENASE 2
(Homo
sapiens)
5 / 12MET A 158
LEU A  97
MET A 206
THR A  41
PHE A 227
None
1.39A21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
5bo6 SIA-ALPHA-2,3-GAL-BE
TA-1,4-GLCNAC-R:ALPH
A
2,8-SIALYLTRANSFERAS
E
(Homo
sapiens)
5 / 12GLY A 302
LEU A 299
GLN A 100
THR A 372
ILE A 316
CDP  A 411 (-3.3A)
None
None
None
None
1.39A21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
5hzw MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN
(Escherichia
coli;
Homo
sapiens)
5 / 12LEU A 130
GLY A 124
GLN A 127
ILE A 115
PHE A 122
None
1.43A15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
5ikr PROSTAGLANDIN G/H
SYNTHASE 2
(Homo
sapiens)
5 / 12LEU A 534
ASN A 537
GLY A 536
GLN A 208
ILE A 337
None
1.10A17.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
5 / 12ASN A 770
GLY A 774
GLN A 776
THR A 945
PHE A 956
ECV  A1101 (-3.1A)
None
ECV  A1101 (-2.9A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
1.29A45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
5 / 12GLN A 776
MET A 807
LEU A 814
ARG A 817
MET A 852
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
1.31A45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
8 / 12LEU A 769
ASN A 770
GLN A 776
MET A 807
LEU A 814
ARG A 817
THR A 945
PHE A 956
ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
ECV  A1101 (-3.6A)
ECV  A1101 (-4.1A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
0.57A45.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
5n6c D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
(Homo
sapiens)
5 / 12LEU A 217
ASN A 218
GLY A 215
LEU A 151
GLN A 224
None
1.43A16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
5nzp D-3-PHOSPHOGLYCERATE
DEHYDROGENASE
(Homo
sapiens)
5 / 12LEU B 217
ASN B 218
GLY B 215
LEU B 151
GLN B 224
None
None
None
9EW  B 301 ( 4.8A)
None
1.30A22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)
6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG
LARGE PROLINE-RICH
PROTEIN BAG6
(Homo
sapiens)
5 / 12GLN C1023
LEU A 266
THR A 220
ILE A 226
PHE A 232
None
1.46A13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)
2ayn UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 14
(Homo
sapiens)
3 / 3MET A 180
MET A 206
TYR A 150
None
1.26A20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)
2dao TRANSCRIPTION FACTOR
ETV6
(Homo
sapiens)
3 / 3MET A  97
MET A  90
TYR A  16
None
1.32A18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)
2gjt RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE PTPRO
(Homo
sapiens)
3 / 3MET A1024
MET A 984
TYR A 992
None
1.42A19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)
3dh1 TRNA-SPECIFIC
ADENOSINE DEAMINASE
2
(Homo
sapiens)
3 / 3MET A  30
MET A  48
TYR A 158
None
1.39A20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)
3hqi SPECKLE-TYPE POZ
PROTEIN
(Homo
sapiens)
3 / 3MET A 255
MET A 288
TYR A 280
None
1.19A20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)
3htm SPECKLE-TYPE POZ
PROTEIN
(Homo
sapiens)
3 / 3MET A 255
MET A 288
TYR A 280
None
1.25A19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)
3kuq RHO
GTPASE-ACTIVATING
PROTEIN 7
(Homo
sapiens)
3 / 3MET A1099
MET A1128
TYR A1153
None
1.17A24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)
4eoz SPECKLE-TYPE POZ
PROTEIN
(Homo
sapiens)
3 / 3MET A 255
MET A 288
TYR A 280
None
1.23A19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)
4j8z SPECKLE-TYPE POZ
PROTEIN
(Homo
sapiens)
3 / 3MET A 255
MET A 288
TYR A 280
None
1.27A21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)
4x0r INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX2
(Homo
sapiens)
3 / 3MET B 155
MET B 112
TYR B 212
None
1.34A21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)
5vni PROTEIN TRANSPORT
PROTEIN SEC23A
(Homo
sapiens)
3 / 3MET A 287
MET A 360
TYR A 370
None
1.21A16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)
6eot DIPEPTIDYL PEPTIDASE
8
(Homo
sapiens)
3 / 3MET A 722
MET A 813
TYR A 787
None
1.34A15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)
6fkq NETRIN-1
(Homo
sapiens)
3 / 3MET A 210
MET A 159
TYR A 272
SO4  A 510 ( 4.4A)
None
None
1.39A20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)
6fuy VINCULIN
(Homo
sapiens)
3 / 3MET A  94
MET A  26
TYR A 107
None
1.16A14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)
1m1l SUPPRESSOR OF FUSED
(Homo
sapiens)
5 / 12MET A 177
GLY A 158
GLN A 217
ARG A 224
PHE A 155
None
1.48A19.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
6 / 12ASN A 705
GLY A 708
GLN A 711
MET A 742
ARG A 752
PHE A 891
BHM  A   1 (-3.6A)
BHM  A   1 ( 3.8A)
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
BHM  A   1 (-3.8A)
None
0.84A49.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
5 / 12GLN A 711
MET A 742
ARG A 752
GLN A 783
MET A 787
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
BHM  A   1 (-3.8A)
None
BHM  A   1 (-3.6A)
1.24A49.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)
2ax9 ANDROGEN RECEPTOR
(Homo
sapiens)
5 / 12GLY A 708
GLN A 711
MET A 742
ARG A 752
MET A 787
BHM  A   1 ( 3.8A)
BHM  A   1 (-2.2A)
BHM  A   1 ( 4.0A)
BHM  A   1 (-3.8A)
BHM  A   1 (-3.6A)
0.91A49.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)
3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)
7 / 12ASN A 719
GLY A 722
MET A 756
ARG A 766
MET A 801
THR A 894
PHE A 905
WOW  A   1 (-3.3A)
WOW  A   1 ( 4.3A)
WOW  A   1 ( 4.1A)
WOW  A   1 (-3.8A)
WOW  A   1 (-4.2A)
WOW  A   1 (-3.9A)
WOW  A   1 (-4.6A)
0.74A54.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)
3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)
6 / 12ASN A 719
TRP A 755
MET A 756
MET A 801
THR A 894
PHE A 905
WOW  A   1 (-3.3A)
None
WOW  A   1 ( 4.1A)
WOW  A   1 (-4.2A)
WOW  A   1 (-3.9A)
WOW  A   1 (-4.6A)
1.18A54.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)
3kba PROGESTERONE
RECEPTOR
(Homo
sapiens)
5 / 12GLY A 722
GLN A 725
MET A 756
ARG A 766
MET A 801
WOW  A   1 ( 4.3A)
WOW  A   1 ( 4.1A)
WOW  A   1 ( 4.1A)
WOW  A   1 (-3.8A)
WOW  A   1 (-4.2A)
0.92A54.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
7 / 12ASN A 564
GLY A 568
TRP A 600
MET A 601
THR A 739
ILE A 747
PHE A 749
MOF  A 801 (-3.0A)
None
None
MOF  A 801 (-3.7A)
MOF  A 801 (-3.9A)
MOF  A 801 ( 4.4A)
MOF  A 801 (-4.4A)
0.95A98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)
4p6w GLUCOCORTICOID
RECEPTOR
(Homo
sapiens)
11 / 12MET A 560
ASN A 564
GLY A 567
GLN A 570
TRP A 600
MET A 601
ARG A 611
MET A 646
THR A 739
ILE A 747
PHE A 749
MOF  A 801 (-3.9A)
MOF  A 801 (-3.0A)
MOF  A 801 (-3.4A)
MOF  A 801 (-2.9A)
None
MOF  A 801 (-3.7A)
MOF  A 801 (-4.2A)
MOF  A 801 (-4.4A)
MOF  A 801 (-3.9A)
MOF  A 801 ( 4.4A)
MOF  A 801 (-4.4A)
0.41A98.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)
4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
8 / 12ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
MET A 852
THR A 945
PHE A 956
CV7  A1987 (-3.1A)
CV7  A1987 (-3.0A)
None
CV7  A1987 ( 3.9A)
CV7  A1987 (-3.7A)
CV7  A1987 ( 3.7A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
0.72A54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)
4udb MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
5 / 12ASN A 770
GLY A 774
TRP A 806
THR A 945
PHE A 956
CV7  A1987 (-3.1A)
None
None
CV7  A1987 (-3.1A)
CV7  A1987 ( 4.7A)
1.12A54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)
5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
7 / 12ASN A 770
GLN A 776
TRP A 806
MET A 807
ARG A 817
THR A 945
PHE A 956
ECV  A1101 (-3.1A)
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
0.45A45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)
5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
5 / 12ASN A 770
GLY A 774
TRP A 806
THR A 945
PHE A 956
ECV  A1101 (-3.1A)
None
None
ECV  A1101 (-3.2A)
ECV  A1101 ( 4.7A)
1.04A45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)
5mwp MINERALOCORTICOID
RECEPTOR
(Homo
sapiens)
5 / 12GLN A 776
TRP A 806
MET A 807
ARG A 817
MET A 852
ECV  A1101 (-2.9A)
None
ECV  A1101 (-3.6A)
ECV  A1101 (-4.0A)
ECV  A1101 (-3.7A)
1.29A45.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)
2aw5 NADP-DEPENDENT MALIC
ENZYME
(Homo
sapiens)
5 / 12VAL A 276
ALA A 274
ARG A 155
ILE A 270
ASN A 454
None
1.44A20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)
3o65 PUTATIVE
ATAXIN-3-LIKE
PROTEIN
(Homo
sapiens)
5 / 12PHE A 127
LYS A   1
ILE A   5
PHE A 132
ASN A 133
None
1.34A18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)
3u1k POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE 1, MITOCHONDRIAL
(Homo
sapiens)
5 / 12ARG A 617
PHE A 647
ILE A 639
PHE A 620
ASN A 627
None
1.25A21.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HGC_A_HCYA501_1
(SERPIN)
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN
(Homo
sapiens)
5 / 12THR A 240
PHE A 242
ILE A 263
SER A 267
PHE A 366
None
0.80A41.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)
4fdh CYTOCHROME P450
11B2, MITOCHONDRIAL
(Homo
sapiens)
5 / 12PRO A 322
THR A 475
ILE A 481
SER A 494
PHE A 328
None
1.35A20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)
4fzd SERINE/THREONINE-PRO
TEIN KINASE MST4
(Homo
sapiens)
5 / 12PRO B 115
PHE B 273
ILE B 121
GLN B 120
PHE B 247
None
1.40A21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)
4fzd SERINE/THREONINE-PRO
TEIN KINASE MST4
(Homo
sapiens)
5 / 12THR B 244
PHE B 273
ILE B 121
GLN B 120
PHE B 247
None
1.36A21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)
4n40 PROTEIN ECT2
(Homo
sapiens)
5 / 12VAL A 123
ALA A  68
ILE A  66
GLN A  62
PHE A  76
None
1.07A20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)
4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE
(Homo
sapiens)
5 / 12VAL A 194
THR A 292
LYS A 318
ILE A 319
SER A 329
None
1.28A18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)
5bwa ORNITHINE
DECARBOXYLASE
(Homo
sapiens)
5 / 12VAL A 192
THR A  63
PHE A  65
ILE A 109
GLN A 129
None
1.29A23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)
5v8w INTEGRATOR COMPLEX
SUBUNIT 9
(Homo
sapiens)
5 / 12VAL A 608
THR A 597
PHE A 654
ILE A 589
PHE A 594
None
1.40A15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)
6bdz DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 10
(Homo
sapiens)
5 / 12ALA A 315
ARG A 321
THR A 319
PHE A 300
GLN A 307
None
None
None
None
NAG  A 701 (-3.8A)
1.41A11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)
6bq1 PHOSPHATIDYLINOSITOL
4-KINASE III ALPHA
(PI4KA)
(Homo
sapiens)
5 / 12ALA A2033
THR A2053
PHE A1980
ILE A1864
GLN A1863
None
1.34A0.00