POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_A_DSFA319_1 (GLR4197 PROTEIN)	1l1o	REPLICATION PROTEIN A 32 KDA SUBUNIT (Homo sapiens)	5 / 9	ILE B  94 VAL B 120 TYR B 125 THR B 124 ILE B  79	None	1.40A	20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_A_DSFA319_1 (GLR4197 PROTEIN)	1suv	TRANSFERRIN RECEPTOR PROTEIN 1 (Homo sapiens)	5 / 9	PRO A 444 ILE A 448 VAL A 403 THR A 602 ILE A 599	None	1.45A	19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_A_DSFA319_1 (GLR4197 PROTEIN)	1z68	FIBROBLAST ACTIVATION PROTEIN, ALPHA SUBUNIT (Homo sapiens)	5 / 9	TYR A  79 TYR A  67 ILE A  62 TYR A  87 ILE A  89	None	1.20A	18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_A_DSFA319_1 (GLR4197 PROTEIN)	2a1a	INTERFERON-INDUCED, DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE (Homo sapiens)	5 / 9	ILE B 430 ILE B 420 VAL B 402 TYR B 454 ILE B 477	None	1.29A	23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_A_DSFA319_1 (GLR4197 PROTEIN)	2g1s	RENIN (Homo sapiens)	5 / 9	TYR A 279 ILE A 263 VAL A 205 TYR A 250 ILE A 234	None	1.45A	21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_A_DSFA319_1 (GLR4197 PROTEIN)	4fm9	DNA TOPOISOMERASE 2-ALPHA (Homo sapiens)	5 / 9	TYR A 518 ILE A 507 ILE A 510 VAL A 493 ILE A 557	None	1.44A	17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_A_DSFA319_1 (GLR4197 PROTEIN)	4hpf	POTASSIUM CHANNEL SUBFAMILY U MEMBER 1 (Homo sapiens)	5 / 9	ILE A 447 ILE A 449 VAL A 433 TYR A 457 ILE A 427	None	1.39A	19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_A_DSFA319_1 (GLR4197 PROTEIN)	5k8d	COAGULATION FACTOR VIII,IG GAMMA-1 CHAIN C REGION (Homo sapiens)	5 / 9	TYR B1837 ILE B1771 VAL B1773 TYR B1786 ILE B1790	None	1.42A	17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_A_DSFA319_1 (GLR4197 PROTEIN)	5lgg	ANAPHASE-PROMOTING COMPLEX SUBUNIT 1,ANAPHASE-PROMOTING COMPLEX SUBUNIT 1,ANAPHASE-PROMOTING COMPLEX SUBUNIT 1,ANAPHASE-PROMOTING COMPLEX SUBUNIT 1 (Homo sapiens)	5 / 9	ILE A  12 ILE A 609 VAL A 506 THR A 487 ILE A 485	None	1.30A	22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_A_DSFA319_1 (GLR4197 PROTEIN)	5w5j	RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2 (Homo sapiens)	5 / 9	ILE A 162 ILE A 152 VAL A 132 TYR A 192 ILE A 218	None	1.19A	24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_B_DSFB319_1 (GLR4197 PROTEIN)	2jdf	GAMMA CRYSTALLIN B (Homo sapiens)	5 / 9	PRO A 148 ILE A  81 MET A  43 VAL A 170 ILE A 132	None	1.11A	18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_B_DSFB319_1 (GLR4197 PROTEIN)	2z17	PLECKSTRIN HOMOLOGY SEC7 AND COILED-COIL DOMAINS-BINDING PROTEIN (Homo sapiens)	5 / 9	ILE A  33 ILE A  52 VAL A  88 ILE A 101 ILE A  75	None	1.24A	13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_B_DSFB319_1 (GLR4197 PROTEIN)	3su8	PLEXIN-B1 (Homo sapiens)	5 / 9	PRO X1706 ILE X1940 VAL X1699 ILE X1990 ILE X1989	None	1.17A	20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_B_DSFB319_1 (GLR4197 PROTEIN)	3tow	MULTIVESICULAR BODY SUBUNIT 12B (Homo sapiens)	5 / 9	ILE A 148 MET A 114 VAL A  53 ILE A 160 ILE A 163	None	1.24A	19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_B_DSFB319_1 (GLR4197 PROTEIN)	5okl	AFAMIN (Homo sapiens)	5 / 9	PRO A 419 TYR A 498 VAL A 534 THR A 415 ILE A 412	None	1.21A	12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_C_DSFC320_1 (GLR4197 PROTEIN)	1fpr	PROTEIN-TYROSINE PHOSPHATASE 1C (Homo sapiens)	4 / 8	TYR A 511 TYR A 507 ILE A 490 ILE A 468	None	0.74A	19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_C_DSFC320_1 (GLR4197 PROTEIN)	1h2u	20 KDA NUCLEAR CAP BINDING PROTEIN (Homo sapiens)	4 / 8	TYR X  57 ILE X  56 VAL X  86 ILE X 101	None	0.88A	17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_C_DSFC320_1 (GLR4197 PROTEIN)	1ldk	CULLIN HOMOLOG (Homo sapiens)	4 / 8	TYR B 455 ILE A 403 ILE B 456 VAL A 370	None	0.84A	24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_C_DSFC320_1 (GLR4197 PROTEIN)	2uzx	HEPATOCYTE GROWTH FACTOR RECEPTOR (Homo sapiens)	4 / 8	TYR B 321 ILE B 446 VAL B 492 ILE B 452	None	0.83A	18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_C_DSFC320_1 (GLR4197 PROTEIN)	2yqe	JUMONJI/ARID DOMAIN-CONTAINING PROTEIN 1D (Homo sapiens)	4 / 8	TYR A 164 ILE A 161 ILE A 160 ILE A 102	None	0.87A	17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_C_DSFC320_1 (GLR4197 PROTEIN)	3ihy	PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3 (Homo sapiens)	4 / 8	ILE A 738 ILE A 735 VAL A 842 ILE A 647	None	0.84A	22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_C_DSFC320_1 (GLR4197 PROTEIN)	3mda	DNA POLYMERASE LAMBDA (Homo sapiens)	4 / 8	TYR A 496 PRO A 435 THR A 433 ILE A 432	None	0.72A	23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_C_DSFC320_1 (GLR4197 PROTEIN)	3qyb	TBC1 DOMAIN FAMILY MEMBER 4 (Homo sapiens)	4 / 8	ILE A1108 ILE A1109 VAL A1164 ILE A1117	None	0.65A	23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_C_DSFC320_1 (GLR4197 PROTEIN)	4y07	NEDD4-LIKE E3 UBIQUITIN-PROTEIN LIGASE WWP2 (Homo sapiens)	4 / 8	ILE A 608 VAL A 571 THR A 624 ILE A 622	None	0.67A	18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_C_DSFC320_1 (GLR4197 PROTEIN)	5c4g	PHOSPHATIDYLINOSITOL 4-KINASE BETA (Homo sapiens)	4 / 8	TYR E 197 ILE E 141 ILE E 145 ILE E 160	None	0.79A	20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_C_DSFC320_1 (GLR4197 PROTEIN)	5ol8	TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL (Homo sapiens)	4 / 8	TYR A 229 ILE A 171 ILE A 173 ILE A 219	None	0.85A	22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_C_DSFC320_1 (GLR4197 PROTEIN)	5ola	TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL (Homo sapiens)	4 / 8	TYR A 229 ILE A 171 ILE A 173 ILE A 219	None	0.88A	20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_C_DSFC320_1 (GLR4197 PROTEIN)	5tj7	NEDD4-LIKE E3 UBIQUITIN-PROTEIN LIGASE WWP2 (Homo sapiens)	4 / 8	ILE A 608 VAL A 571 THR A 624 ILE A 622	None	0.73A	19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_D_DSFD319_1 (GLR4197 PROTEIN)	1z68	FIBROBLAST ACTIVATION PROTEIN, ALPHA SUBUNIT (Homo sapiens)	5 / 10	TYR A  67 ILE A  62 TYR A  87 ILE A  89 ILE A  76	None	0.90A	18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_D_DSFD319_1 (GLR4197 PROTEIN)	2jdf	GAMMA CRYSTALLIN B (Homo sapiens)	5 / 10	PRO A 148 ILE A  81 MET A  43 VAL A 170 ILE A 132	None	1.12A	18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_D_DSFD319_1 (GLR4197 PROTEIN)	3su8	PLEXIN-B1 (Homo sapiens)	5 / 10	PRO X1706 ILE X1940 VAL X1699 ILE X1990 ILE X1989	None	1.17A	20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_D_DSFD319_1 (GLR4197 PROTEIN)	3tow	MULTIVESICULAR BODY SUBUNIT 12B (Homo sapiens)	5 / 10	ILE A 148 MET A 114 VAL A  53 ILE A 160 ILE A 163	None	1.23A	19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_D_DSFD319_1 (GLR4197 PROTEIN)	5vft	26S PROTEASOME REGULATORY SUBUNIT 8 (Homo sapiens)	5 / 10	ILE C 292 ILE C 245 VAL C 186 ILE C 165 ILE C 161	None	1.15A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_D_DSFD319_1 (GLR4197 PROTEIN)	5w5j	RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2 (Homo sapiens)	5 / 10	ILE A 162 ILE A 152 VAL A 132 TYR A 192 ILE A 218	None	1.18A	24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_D_DSFD319_1 (GLR4197 PROTEIN)	6fyl	DUAL SPECIFICITY PROTEIN KINASE CLK2 (Homo sapiens)	5 / 10	ILE A 296 VAL A 278 TYR A 347 ILE A 370 ILE A 367	None	1.20A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_E_DSFE319_1 (GLR4197 PROTEIN)	1z68	FIBROBLAST ACTIVATION PROTEIN, ALPHA SUBUNIT (Homo sapiens)	5 / 10	TYR A  67 ILE A  62 TYR A  87 ILE A  89 ILE A  76	None	0.89A	18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_E_DSFE319_1 (GLR4197 PROTEIN)	2jdf	GAMMA CRYSTALLIN B (Homo sapiens)	5 / 10	PRO A 148 ILE A  81 MET A  43 VAL A 170 ILE A 132	None	1.13A	18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_E_DSFE319_1 (GLR4197 PROTEIN)	2z17	PLECKSTRIN HOMOLOGY SEC7 AND COILED-COIL DOMAINS-BINDING PROTEIN (Homo sapiens)	5 / 10	ILE A  33 ILE A  52 VAL A  88 ILE A 101 ILE A  75	None	1.23A	13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_E_DSFE319_1 (GLR4197 PROTEIN)	3su8	PLEXIN-B1 (Homo sapiens)	5 / 10	PRO X1706 ILE X1940 VAL X1699 ILE X1990 ILE X1989	None	1.19A	20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_E_DSFE319_1 (GLR4197 PROTEIN)	3tow	MULTIVESICULAR BODY SUBUNIT 12B (Homo sapiens)	5 / 10	ILE A 148 MET A 114 VAL A  53 ILE A 160 ILE A 163	None	1.23A	19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_E_DSFE319_1 (GLR4197 PROTEIN)	5vft	26S PROTEASOME REGULATORY SUBUNIT 8 (Homo sapiens)	5 / 10	ILE C 292 ILE C 245 VAL C 186 ILE C 165 ILE C 161	None	1.16A	undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_E_DSFE319_1 (GLR4197 PROTEIN)	5w5j	RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2 (Homo sapiens)	5 / 10	ILE A 162 ILE A 152 VAL A 132 TYR A 192 ILE A 218	None	1.18A	24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_E_DSFE319_1 (GLR4197 PROTEIN)	6fyl	DUAL SPECIFICITY PROTEIN KINASE CLK2 (Homo sapiens)	5 / 10	ILE A 296 VAL A 278 TYR A 347 ILE A 370 ILE A 367	None	1.20A	undetectable