POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M8D_A_CLWA906_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	1m9q	ENDOTHELIAL NITRIC-OXIDE SYNTHASE (Homo sapiens)	5 / 5	PRO A 334 VAL A 336 TYR A 357 MET A 358 GLU A 361	5NI  A 907 ( 4.8A) 5NI  A 907 (-4.4A) 5NI  A 907 (-4.6A) HEM  A 901 ( 4.4A) HEM  A 901 ( 3.1A)	0.40A	61.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M8D_A_CLWA906_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 5	PRO A 350 VAL A 352 TYR A 373 MET A 374	AT2  A 906 (-4.5A) AT2  A 906 ( 4.8A) None HEM  A 901 ( 4.6A)	0.18A	87.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M8D_A_CLWA906_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 5	VAL A 352 TYR A 373 MET A 374 GLU A 377	AT2  A 906 ( 4.8A) None HEM  A 901 ( 4.6A) AT2  A 906 ( 2.7A)	1.18A	87.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M8D_A_CLWA906_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	4 / 5	PRO A 384 VAL A 401 TYR A 376 GLU A 406	None	1.41A	20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M8D_A_CLWA906_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	4b6l	SERINE/THREONINE-PRO TEIN KINASE PLK3 (Homo sapiens)	4 / 5	PRO A 259 VAL A 275 TYR A 251 MET A 250	None	1.03A	23.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M8D_B_CLWB907_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	1m9q	ENDOTHELIAL NITRIC-OXIDE SYNTHASE (Homo sapiens)	5 / 5	PRO A 334 VAL A 336 TYR A 357 MET A 358 GLU A 361	5NI  A 907 ( 4.8A) 5NI  A 907 (-4.4A) 5NI  A 907 (-4.6A) HEM  A 901 ( 4.4A) HEM  A 901 ( 3.1A)	0.39A	61.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M8D_B_CLWB907_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 5	PRO A 350 VAL A 352 TYR A 373 MET A 374	AT2  A 906 (-4.5A) AT2  A 906 ( 4.8A) None HEM  A 901 ( 4.6A)	0.19A	87.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M8D_B_CLWB907_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	4 / 5	PRO A 384 VAL A 401 TYR A 376 GLU A 406	None	1.43A	20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M8D_B_CLWB907_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	4b6l	SERINE/THREONINE-PRO TEIN KINASE PLK3 (Homo sapiens)	4 / 5	PRO A 259 VAL A 275 TYR A 251 MET A 250	None	1.04A	23.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M9J_A_CLWA906_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	1m9q	ENDOTHELIAL NITRIC-OXIDE SYNTHASE (Homo sapiens)	5 / 5	PRO A 334 VAL A 336 TYR A 357 MET A 358 GLU A 361	5NI  A 907 ( 4.8A) 5NI  A 907 (-4.4A) 5NI  A 907 (-4.6A) HEM  A 901 ( 4.4A) HEM  A 901 ( 3.1A)	0.48A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M9J_A_CLWA906_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	2x47	MACRO DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	4 / 5	PRO A 219 VAL A 120 TYR A 114 GLU A 111	None	1.33A	19.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M9J_A_CLWA906_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 5	PRO A 350 VAL A 352 TYR A 373 MET A 374	AT2  A 906 (-4.5A) AT2  A 906 ( 4.8A) None HEM  A 901 ( 4.6A)	0.31A	60.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M9J_A_CLWA906_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 5	VAL A 352 TYR A 373 MET A 374 GLU A 377	AT2  A 906 ( 4.8A) None HEM  A 901 ( 4.6A) AT2  A 906 ( 2.7A)	1.25A	60.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M9J_A_CLWA906_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	3nyo	G PROTEIN-COUPLED RECEPTOR KINASE 6 (Homo sapiens)	4 / 5	PRO A 384 VAL A 401 TYR A 376 GLU A 406	None	1.41A	21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M9J_A_CLWA906_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	4b6l	SERINE/THREONINE-PRO TEIN KINASE PLK3 (Homo sapiens)	4 / 5	PRO A 259 VAL A 275 TYR A 251 MET A 250	None	1.13A	21.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M9J_B_CLWB907_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	1m9q	ENDOTHELIAL NITRIC-OXIDE SYNTHASE (Homo sapiens)	5 / 5	PRO A 334 VAL A 336 TYR A 357 MET A 358 GLU A 361	5NI  A 907 ( 4.8A) 5NI  A 907 (-4.4A) 5NI  A 907 (-4.6A) HEM  A 901 ( 4.4A) HEM  A 901 ( 3.1A)	0.25A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M9J_B_CLWB907_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 5	PRO A 350 VAL A 352 TYR A 373 MET A 374	AT2  A 906 (-4.5A) AT2  A 906 ( 4.8A) None HEM  A 901 ( 4.6A)	0.24A	60.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M9J_B_CLWB907_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 5	VAL A 352 TYR A 373 MET A 374 GLU A 377	AT2  A 906 ( 4.8A) None HEM  A 901 ( 4.6A) AT2  A 906 ( 2.7A)	1.18A	60.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M9J_B_CLWB907_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	4b6l	SERINE/THREONINE-PRO TEIN KINASE PLK3 (Homo sapiens)	4 / 5	PRO A 259 VAL A 275 TYR A 251 MET A 250	None	1.11A	21.56