POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OSV_B_CHCB201_1 (BILE ACID RECEPTOR)	1s1e	KV CHANNEL INTERACTING PROTEIN 1 (Homo sapiens)	5 / 12	LEU A 192 MET A 182 PHE A 178 TYR A 134 MET A 147	None	1.45A	20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OSV_B_CHCB201_1 (BILE ACID RECEPTOR)	2xa7	AP-2 COMPLEX SUBUNIT BETA (Homo sapiens)	5 / 12	LEU B 396 ILE B 417 PHE B 418 ILE B 428 MET B 448	None	1.37A	16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OSV_B_CHCB201_1 (BILE ACID RECEPTOR)	3edi	TOLLOID-LIKE PROTEIN 1 (Homo sapiens)	5 / 12	LEU A  94 MET A  34 MET A  29 ILE A  19 ILE A  77	None DMS  A 215 ( 3.9A) None None None	1.29A	20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OSV_B_CHCB201_1 (BILE ACID RECEPTOR)	4nky	STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE (Homo sapiens)	5 / 12	LEU A 195 SER A 180 ILE A 179 PHE A 300 ILE A 198	None	1.29A	19.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1OSV_B_CHCB201_1 (BILE ACID RECEPTOR)	4oiv	BILE ACID RECEPTOR (Homo sapiens)	5 / 12	LEU A 291 ILE A 339 ILE A 356 MET A 369 TYR A 373	XX9  A 501 (-4.1A) None XX9  A 501 ( 4.6A) XX9  A 501 (-4.5A) None	1.03A	93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1OSV_B_CHCB201_1 (BILE ACID RECEPTOR)	4oiv	BILE ACID RECEPTOR (Homo sapiens)	5 / 12	LEU A 291 MET A 294 ILE A 356 MET A 369 TYR A 373	XX9  A 501 (-4.1A) XX9  A 501 ( 4.3A) XX9  A 501 ( 4.6A) XX9  A 501 (-4.5A) None	0.83A	93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1OSV_B_CHCB201_1 (BILE ACID RECEPTOR)	4oiv	BILE ACID RECEPTOR (Homo sapiens)	5 / 12	LEU A 291 MET A 294 PHE A 333 ILE A 356 MET A 369	XX9  A 501 (-4.1A) XX9  A 501 ( 4.3A) XX9  A 501 (-4.7A) XX9  A 501 ( 4.6A) XX9  A 501 (-4.5A)	0.81A	93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1OSV_B_CHCB201_1 (BILE ACID RECEPTOR)	4oiv	BILE ACID RECEPTOR (Homo sapiens)	5 / 12	LEU A 291 MET A 294 PHE A 333 SER A 336 ILE A 356	XX9  A 501 (-4.1A) XX9  A 501 ( 4.3A) XX9  A 501 (-4.7A) XX9  A 501 (-4.2A) XX9  A 501 ( 4.6A)	0.66A	93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1OSV_B_CHCB201_1 (BILE ACID RECEPTOR)	4oiv	BILE ACID RECEPTOR (Homo sapiens)	5 / 12	LEU A 291 MET A 294 SER A 336 ILE A 356 TYR A 373	XX9  A 501 (-4.1A) XX9  A 501 ( 4.3A) XX9  A 501 (-4.2A) XX9  A 501 ( 4.6A) None	0.94A	93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1OSV_B_CHCB201_1 (BILE ACID RECEPTOR)	4oiv	BILE ACID RECEPTOR (Homo sapiens)	5 / 12	LEU A 291 PHE A 333 ILE A 339 ILE A 356 MET A 369	XX9  A 501 (-4.1A) XX9  A 501 (-4.7A) None XX9  A 501 ( 4.6A) XX9  A 501 (-4.5A)	0.80A	93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1OSV_B_CHCB201_1 (BILE ACID RECEPTOR)	4oiv	BILE ACID RECEPTOR (Homo sapiens)	5 / 12	LEU A 291 PHE A 333 SER A 336 ILE A 339 ILE A 356	XX9  A 501 (-4.1A) XX9  A 501 (-4.7A) XX9  A 501 (-4.2A) None XX9  A 501 ( 4.6A)	0.79A	93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1OSV_B_CHCB201_1 (BILE ACID RECEPTOR)	4oiv	BILE ACID RECEPTOR (Homo sapiens)	5 / 12	LEU A 291 SER A 336 ILE A 339 ILE A 356 TYR A 373	XX9  A 501 (-4.1A) XX9  A 501 (-4.2A) None XX9  A 501 ( 4.6A) None	0.93A	93.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OSV_B_CHCB201_1 (BILE ACID RECEPTOR)	4q6r	SPHINGOSINE-1-PHOSPH ATE LYASE 1 (Homo sapiens)	5 / 12	LEU A 453 MET A 467 SER A 507 ILE A 511 ILE A 440	None None None GOL  A 902 ( 4.7A) None	1.44A	17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OSV_B_CHCB201_1 (BILE ACID RECEPTOR)	5c4t	NUCLEAR RECEPTOR ROR-GAMMA (Homo sapiens)	5 / 12	LEU A 454 SER A 413 ILE A 417 PHE A 412 ILE A 462	None	1.36A	29.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OSV_B_CHCB201_1 (BILE ACID RECEPTOR)	5j3p	TYROSYL-DNA PHOSPHODIESTERASE 2 (Homo sapiens)	5 / 12	LEU A 337 ILE A 117 MET A 183 TYR A 168 TRP A 119	None	1.48A	22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OSV_B_CHCB201_2 (BILE ACID RECEPTOR)	1wuu	GALACTOKINASE (Homo sapiens)	4 / 5	HIS A 311 ARG A 312 ILE A 285 HIS A  44	None None None GLA  A 393 (-3.6A)	1.48A	19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OSV_B_CHCB201_2 (BILE ACID RECEPTOR)	3n3k	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 8 (Homo sapiens)	4 / 5	HIS A1086 ARG A 780 ILE A 791 HIS A1067	None	1.23A	20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OSV_B_CHCB201_2 (BILE ACID RECEPTOR)	5hdt	SISTER CHROMATID COHESION PROTEIN PDS5 HOMOLOG B (Homo sapiens)	4 / 5	HIS A  71 ARG A  77 ILE A  87 HIS A  62	None	1.46A	12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OT7_A_CHCA1001_1 (BILE ACID RECEPTOR)	2ax4	BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHETASE 2 (Homo sapiens)	5 / 12	ARG A 176 ILE A 182 PHE A 185 ILE A 132 TYR A 174	None	1.43A	22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OT7_A_CHCA1001_1 (BILE ACID RECEPTOR)	3no8	BTB/POZ DOMAIN-CONTAINING PROTEIN 2 (Homo sapiens)	5 / 12	PHE A 523 ARG A 376 ILE A 518 PHE A 406 ILE A 424	None	1.35A	18.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1OT7_A_CHCA1001_1 (BILE ACID RECEPTOR)	4oiv	BILE ACID RECEPTOR (Homo sapiens)	5 / 12	ARG A 335 SER A 336 ILE A 339 ILE A 356 TYR A 373	None XX9  A 501 (-4.2A) None XX9  A 501 ( 4.6A) None	0.92A	93.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1OT7_A_CHCA1001_1 (BILE ACID RECEPTOR)	4oiv	BILE ACID RECEPTOR (Homo sapiens)	5 / 12	PHE A 333 ARG A 335 SER A 336 ILE A 339 ILE A 356	XX9  A 501 (-4.7A) None XX9  A 501 (-4.2A) None XX9  A 501 ( 4.6A)	0.88A	93.81