POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_A_BQ1A1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	1rw2	ATP-DEPENDENT DNA HELICASE II, 80 KDA SUBUNIT (Homo sapiens)	3 / 3	GLU A  87 ALA A  88 PHE A  91	None	0.31A	19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_A_BQ1A1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	4px9	ATP-DEPENDENT RNA HELICASE DDX3X (Homo sapiens)	3 / 3	GLU A 285 ALA A 286 PHE A 289	ADP  A 601 ( 4.4A) None None	0.63A	15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_A_BQ1A1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5a15	BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD16 (Homo sapiens)	3 / 3	GLU A 109 ALA A 110 PHE A 113	None	0.33A	22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_A_BQ1A1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5bxd	BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD1 (Homo sapiens)	3 / 3	GLU A 111 ALA A 112 PHE A 115	None	0.33A	21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_A_BQ1A1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5bxh	BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD9 (Homo sapiens)	3 / 3	GLU A  86 ALA A  87 PHE A  90	None	0.27A	22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_A_BQ1A1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5dse	TETRATRICOPEPTIDE REPEAT PROTEIN 7B (Homo sapiens)	3 / 3	GLU A 450 ALA A 451 PHE A 454	None	0.53A	7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_A_BQ1A1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5e7j	ATP-DEPENDENT RNA HELICASE DDX3X (Homo sapiens)	3 / 3	GLU A 285 ALA A 286 PHE A 289	AMP  A 801 ( 4.5A) None None	0.63A	9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_A_BQ1A1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5gli	ENDOTHELIN RECEPTOR SUBTYPE-B (Homo sapiens)	3 / 3	GLU A 236 ALA A 237 PHE A 240	None	0.26A	12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_A_BQ1A1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5u0i	GLUTAMINASE KIDNEY ISOFORM, MITOCHONDRIAL (Homo sapiens)	3 / 3	GLU A 626 ALA A 627 PHE A 630	None	0.51A	20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_B_BQ1B1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	1dpt	D-DOPACHROME TAUTOMERASE (Homo sapiens)	5 / 8	ALA A  26 ALA A  25 ALA A  78 PHE A  81 LEU A  84	None	1.22A	25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_B_BQ1B1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	2hi4	CYTOCHROME P450 1A2 (Homo sapiens)	5 / 8	ALA A 464 ILE A 468 ALA A 370 PHE A 371 LEU A 472	HEM  A 900 (-3.6A) None None None None	1.31A	11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_B_BQ1B1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	2k9u	GAMMA FILAMIN (Homo sapiens)	5 / 8	ALA A  23 ILE A  41 ALA A  18 PHE A  91 LEU A  51	None	1.36A	23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_B_BQ1B1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	2m6b	FULL-LENGTH TRANSMEMBRANE DOMAINS OF HUMAN GLYCINE RECEPTOR ALPHA1 SUBUNIT (Homo sapiens)	5 / 8	ALA A 406 ILE A 409 ALA A 297 PHE A 295 LEU A 292	None	1.38A	20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_C_BQ1C1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	1rw2	ATP-DEPENDENT DNA HELICASE II, 80 KDA SUBUNIT (Homo sapiens)	3 / 3	GLU A  87 ALA A  88 PHE A  91	None	0.37A	19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_C_BQ1C1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	4px9	ATP-DEPENDENT RNA HELICASE DDX3X (Homo sapiens)	3 / 3	GLU A 285 ALA A 286 PHE A 289	ADP  A 601 ( 4.4A) None None	0.63A	15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_C_BQ1C1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5a15	BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD16 (Homo sapiens)	3 / 3	GLU A 109 ALA A 110 PHE A 113	None	0.37A	22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_C_BQ1C1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5bxd	BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD1 (Homo sapiens)	3 / 3	GLU A 111 ALA A 112 PHE A 115	None	0.38A	21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_C_BQ1C1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5bxh	BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD9 (Homo sapiens)	3 / 3	GLU A  86 ALA A  87 PHE A  90	None	0.29A	22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_C_BQ1C1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5dse	TETRATRICOPEPTIDE REPEAT PROTEIN 7B (Homo sapiens)	3 / 3	GLU A 450 ALA A 451 PHE A 454	None	0.59A	7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_C_BQ1C1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5e7j	ATP-DEPENDENT RNA HELICASE DDX3X (Homo sapiens)	3 / 3	GLU A 285 ALA A 286 PHE A 289	AMP  A 801 ( 4.5A) None None	0.64A	9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_C_BQ1C1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5eqi	SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 1 (Homo sapiens)	3 / 3	GLU A 380 ALA A 377 PHE A 379	5RH  A 501 ( 3.6A) None 5RH  A 501 ( 4.5A)	0.65A	11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_C_BQ1C1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5gli	ENDOTHELIN RECEPTOR SUBTYPE-B (Homo sapiens)	3 / 3	GLU A 236 ALA A 237 PHE A 240	None	0.23A	12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_C_BQ1C1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5u0i	GLUTAMINASE KIDNEY ISOFORM, MITOCHONDRIAL (Homo sapiens)	3 / 3	GLU A 626 ALA A 627 PHE A 630	None	0.48A	20.71