POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	1z68	FIBROBLAST ACTIVATION PROTEIN, ALPHA SUBUNIT (Homo sapiens)	12 / 12	ARG A 123 GLU A 203 GLU A 204 TYR A 541 SER A 624 TYR A 625 VAL A 650 TYR A 656 TYR A 660 ASN A 704 VAL A 705 HIS A 734	None	0.48A	53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	1z68	FIBROBLAST ACTIVATION PROTEIN, ALPHA SUBUNIT (Homo sapiens)	5 / 12	TYR A 628 TYR A 656 ASN A 704 VAL A 705 HIS A 734	None	1.00A	53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	2g5t	DIPEPTIDYL PEPTIDASE 4 (Homo sapiens)	12 / 12	ARG A 125 GLU A 205 GLU A 206 TYR A 547 SER A 630 TYR A 631 VAL A 656 TYR A 662 TYR A 666 ASN A 710 VAL A 711 HIS A 740	ACF  A 800 (-3.4A) ACF  A 800 (-3.6A) ACF  A 800 (-3.2A) ACF  A 800 (-4.5A) ACF  A 800 (-1.3A) None None ACF  A 800 (-4.1A) ACF  A 800 (-3.3A) ACF  A 800 (-3.3A) None None	0.24A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	2g5t	DIPEPTIDYL PEPTIDASE 4 (Homo sapiens)	5 / 12	TYR A 634 TYR A 662 ASN A 710 VAL A 711 HIS A 740	None ACF  A 800 (-4.1A) ACF  A 800 (-3.3A) None None	1.07A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	3ddu	PROLYL ENDOPEPTIDASE (Homo sapiens)	5 / 12	TYR A 473 SER A 554 VAL A 580 VAL A 644 HIS A 680	ACT  A 801 (-4.5A) ACT  A 801 ( 2.6A) None None ACT  A 801 (-3.8A)	0.32A	22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	4w82	FATTY ACID SYNTHASE (Homo sapiens)	5 / 12	GLU A1768 SER A1756 ASN A1746 VAL A1744 HIS A1674	None	1.44A	20.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	4wjl	INACTIVE DIPEPTIDYL PEPTIDASE 10 (Homo sapiens)	5 / 12	GLU A 233 TYR A 652 TYR A 683 VAL A 730 HIS A 759	None	0.67A	36.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	4wjl	INACTIVE DIPEPTIDYL PEPTIDASE 10 (Homo sapiens)	5 / 12	GLU A 234 TYR A 652 TYR A 683 VAL A 730 HIS A 759	None	0.53A	36.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	5vbb	RNA PSEUDOURIDYLATE SYNTHASE DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 12	GLU A 109 SER A 162 VAL A 164 VAL A 150 HIS A 153	None	1.36A	18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	6eoq	DIPEPTIDYL PEPTIDASE 9 (Homo sapiens)	10 / 12	GLU A 249 TYR A 644 SER A 730 TYR A 731 VAL A 756 TYR A 762 TYR A 766 ASN A 810 VAL A 811 HIS A 840	None	0.52A	6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	6eoq	DIPEPTIDYL PEPTIDASE 9 (Homo sapiens)	5 / 12	GLU A 249 TYR A 644 SER A 730 TYR A 762 VAL A 811	None	1.10A	6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	6eot	DIPEPTIDYL PEPTIDASE 8 (Homo sapiens)	12 / 12	ARG A 160 GLU A 275 GLU A 276 TYR A 669 SER A 755 TYR A 756 VAL A 781 TYR A 787 TYR A 791 ASN A 835 VAL A 836 HIS A 865	None	0.69A	7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	6eot	DIPEPTIDYL PEPTIDASE 8 (Homo sapiens)	6 / 12	GLU A 275 TYR A 669 SER A 755 VAL A 781 TYR A 787 VAL A 836	None	1.11A	7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	6eot	DIPEPTIDYL PEPTIDASE 8 (Homo sapiens)	6 / 12	SER A 755 TYR A 759 TYR A 787 ASN A 835 VAL A 836 HIS A 865	None	1.17A	7.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BJM_B_BJMB2_1 (DIPEPTIDYL PEPTIDASE 4)	1z68	FIBROBLAST ACTIVATION PROTEIN, ALPHA SUBUNIT (Homo sapiens)	11 / 12	ARG A 123 GLU A 203 GLU A 204 TYR A 541 SER A 624 VAL A 650 TYR A 656 TYR A 660 ASN A 704 VAL A 705 HIS A 734	None	0.52A	53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BJM_B_BJMB2_1 (DIPEPTIDYL PEPTIDASE 4)	1z68	FIBROBLAST ACTIVATION PROTEIN, ALPHA SUBUNIT (Homo sapiens)	5 / 12	ARG A 123 PHE A 350 TYR A 541 SER A 624 TYR A 660	None	1.19A	53.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BJM_B_BJMB2_1 (DIPEPTIDYL PEPTIDASE 4)	2g5t	DIPEPTIDYL PEPTIDASE 4 (Homo sapiens)	12 / 12	ARG A 125 GLU A 205 GLU A 206 PHE A 357 TYR A 547 SER A 630 VAL A 656 TYR A 662 TYR A 666 ASN A 710 VAL A 711 HIS A 740	ACF  A 800 (-3.4A) ACF  A 800 (-3.6A) ACF  A 800 (-3.2A) None ACF  A 800 (-4.5A) ACF  A 800 (-1.3A) None ACF  A 800 (-4.1A) ACF  A 800 (-3.3A) ACF  A 800 (-3.3A) None None	0.30A	100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3BJM_B_BJMB2_1 (DIPEPTIDYL PEPTIDASE 4)	2g5t	DIPEPTIDYL PEPTIDASE 4 (Homo sapiens)	7 / 12	GLU A 205 PHE A 357 TYR A 547 SER A 630 VAL A 656 TYR A 662 VAL A 711	ACF  A 800 (-3.6A) None ACF  A 800 (-4.5A) ACF  A 800 (-1.3A) None ACF  A 800 (-4.1A) None	1.34A	100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_B_BJMB2_1 (DIPEPTIDYL PEPTIDASE 4)	3ddu	PROLYL ENDOPEPTIDASE (Homo sapiens)	5 / 12	TYR A 473 SER A 554 VAL A 580 VAL A 644 HIS A 680	ACT  A 801 (-4.5A) ACT  A 801 ( 2.6A) None None ACT  A 801 (-3.8A)	0.33A	22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_B_BJMB2_1 (DIPEPTIDYL PEPTIDASE 4)	3i6u	SERINE/THREONINE-PRO TEIN KINASE CHK2 (Homo sapiens)	5 / 12	GLU A 219 VAL A 246 TYR A 220 ASN A 290 VAL A 300	None	1.24A	21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_B_BJMB2_1 (DIPEPTIDYL PEPTIDASE 4)	3rze	HISTAMINE H1 RECEPTOR, LYSOZYME CHIMERA (Escherichia virus T4; Homo sapiens)	5 / 12	PHE A 435 VAL A  76 TYR A 458 ASN A  84 VAL A  80	D7V  A1201 ( 3.8A) None 5EH  A1200 ( 4.4A) None None	1.43A	20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_B_BJMB2_1 (DIPEPTIDYL PEPTIDASE 4)	4w82	FATTY ACID SYNTHASE (Homo sapiens)	5 / 12	GLU A1768 SER A1756 ASN A1746 VAL A1744 HIS A1674	None	1.48A	20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_B_BJMB2_1 (DIPEPTIDYL PEPTIDASE 4)	5vbb	RNA PSEUDOURIDYLATE SYNTHASE DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 12	GLU A 109 SER A 162 VAL A 164 VAL A 150 HIS A 153	None	1.32A	18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_B_BJMB2_1 (DIPEPTIDYL PEPTIDASE 4)	6eoq	DIPEPTIDYL PEPTIDASE 9 (Homo sapiens)	5 / 12	GLU A 249 TYR A 644 SER A 730 TYR A 762 VAL A 811	None	1.10A	6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_B_BJMB2_1 (DIPEPTIDYL PEPTIDASE 4)	6eoq	DIPEPTIDYL PEPTIDASE 9 (Homo sapiens)	9 / 12	GLU A 249 TYR A 644 SER A 730 VAL A 756 TYR A 762 TYR A 766 ASN A 810 VAL A 811 HIS A 840	None	0.51A	6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_B_BJMB2_1 (DIPEPTIDYL PEPTIDASE 4)	6eot	DIPEPTIDYL PEPTIDASE 8 (Homo sapiens)	11 / 12	ARG A 160 GLU A 275 GLU A 276 TYR A 669 SER A 755 VAL A 781 TYR A 787 TYR A 791 ASN A 835 VAL A 836 HIS A 865	None	0.72A	7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_B_BJMB2_1 (DIPEPTIDYL PEPTIDASE 4)	6eot	DIPEPTIDYL PEPTIDASE 8 (Homo sapiens)	6 / 12	GLU A 275 TYR A 669 SER A 755 VAL A 781 TYR A 787 VAL A 836	None	1.11A	7.26