POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Q1S_A_AWYA1103_0 (DNA CROSS-LINK REPAIR 1A PROTEIN)	1gz4	NAD-DEPENDENT MALIC ENZYME (Homo sapiens)	4 / 6	VAL A 553 LYS A 549 ILE A 524 LYS A 529	None	1.36A	20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Q1S_A_AWYA1103_0 (DNA CROSS-LINK REPAIR 1A PROTEIN)	2jif	SHORT/BRANCHED CHAIN SPECIFIC ACYL-COA DEHYDROGENASE (Homo sapiens)	4 / 6	VAL A 400 LYS A 402 ILE A 386 LYS A 396	None	1.46A	22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Q1S_A_AWYA1103_0 (DNA CROSS-LINK REPAIR 1A PROTEIN)	2r8u	MICROTUBULE-ASSOCIAT ED PROTEIN RP/EB FAMILY MEMBER 1 (Homo sapiens)	4 / 6	LYS A 100 VAL A  93 LYS A  95 ILE A  72	None	1.00A	19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Q1S_A_AWYA1103_0 (DNA CROSS-LINK REPAIR 1A PROTEIN)	3vvw	CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 (Homo sapiens)	4 / 6	VAL A  75 ILE A  79 LYS A  88 TYR A  42	None	1.40A	14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Q1S_A_AWYA1103_0 (DNA CROSS-LINK REPAIR 1A PROTEIN)	4bxo	FANCONI ANEMIA GROUP M PROTEIN (Homo sapiens)	4 / 6	LYS A1877 VAL A1898 ILE A1932 TYR A1918	None	1.42A	22.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5Q1S_A_AWYA1103_0 (DNA CROSS-LINK REPAIR 1A PROTEIN)	5ahr	DNA CROSS-LINK REPAIR 1A PROTEIN (Homo sapiens)	6 / 6	LYS A 831 VAL A1004 LYS A1008 ILE A1012 LYS A1035 TYR A1040	None	0.48A	99.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Q1S_A_AWYA1103_0 (DNA CROSS-LINK REPAIR 1A PROTEIN)	5ikr	PROSTAGLANDIN G/H SYNTHASE 2 (Homo sapiens)	4 / 6	LYS A 468 VAL A 501 ILE A 498 LYS A 166	None	1.22A	21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Q1S_A_AWYA1103_0 (DNA CROSS-LINK REPAIR 1A PROTEIN)	5j9s	PROTEIN ENL (Homo sapiens)	4 / 6	VAL A  87 LYS A  50 ILE A  44 LYS A  90	None SO4  A 201 (-3.2A) None None	0.90A	18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Q1S_A_AWYA1103_0 (DNA CROSS-LINK REPAIR 1A PROTEIN)	5lt1	KINESIN-LIKE PROTEIN (Homo sapiens)	4 / 6	LYS A 150 VAL A 155 LYS A 166 ILE A 285	None	1.24A	25.35