POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IEO_A_AMJA300_0 (CARBONIC ANHYDRASE 2)	2daq	WHSC1L1 PROTEIN, ISOFORM LONG (Homo sapiens)	4 / 4	ILE A  29 GLN A  13 VAL A  15 PHE A  49	None	1.10A	16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IEO_A_AMJA300_0 (CARBONIC ANHYDRASE 2)	2l4m	UNCHARACTERIZED PROTEIN (Homo sapiens)	4 / 4	ILE A 128 GLN A 123 VAL A 127 PHE A 116	None	1.50A	13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IEO_A_AMJA300_0 (CARBONIC ANHYDRASE 2)	2q6z	UROPORPHYRINOGEN DECARBOXYLASE (Homo sapiens)	4 / 4	ILE A 334 GLN A 302 VAL A 279 PHE A  19	None	1.13A	21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IEO_A_AMJA300_0 (CARBONIC ANHYDRASE 2)	3fnv	CDGSH IRON SULFUR DOMAIN-CONTAINING PROTEIN 2 (Homo sapiens)	4 / 4	ILE A  75 GLN A  76 VAL A  82 PHE A 107	None	1.27A	15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IEO_A_AMJA300_0 (CARBONIC ANHYDRASE 2)	3l43	DYNAMIN-3 (Homo sapiens)	4 / 4	ILE A 135 GLN A  33 VAL A  70 PHE A 163	None	1.26A	21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IEO_A_AMJA300_0 (CARBONIC ANHYDRASE 2)	3qci	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE GAMMA (Homo sapiens)	4 / 4	ILE A1095 GLN A1098 VAL A 912 PHE A1091	None	1.48A	21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IEO_A_AMJA300_0 (CARBONIC ANHYDRASE 2)	4fww	MACROPHAGE-STIMULATI NG PROTEIN RECEPTOR (Homo sapiens)	4 / 4	ILE A 471 GLN A 473 VAL A 520 PHE A 511	None	1.45A	19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IEO_A_AMJA300_0 (CARBONIC ANHYDRASE 2)	4gs4	ALPHA-TUBULIN N-ACETYLTRANSFERASE (Homo sapiens)	4 / 4	ILE A 185 GLN A 179 VAL A 106 PHE A 190	None	1.44A	21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IEO_A_AMJA300_0 (CARBONIC ANHYDRASE 2)	4ooa	CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 2 (Homo sapiens)	4 / 4	ILE A  75 GLN A  76 VAL A  82 PHE A 107	None	1.29A	13.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3IEO_A_AMJA300_0 (CARBONIC ANHYDRASE 2)	4qk3	CARBONIC ANHYDRASE 2 (Homo sapiens)	4 / 4	ILE A  91 GLN A  92 VAL A 121 PHE A 131	None	0.23A	95.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IEO_A_AMJA300_0 (CARBONIC ANHYDRASE 2)	5fhz	ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER A3 (Homo sapiens)	4 / 4	ILE A 419 GLN A 417 VAL A 320 PHE A 330	None	1.13A	20.42