POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)
1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		1gul GLUTATHIONE
TRANSFERASE A4-4
(Homo
sapiens)		4 / 7TYR A 132
ASP A 101
GLU A  97
PHE A 136
None
1.45A14.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		1i71 APOLIPOPROTEIN(A)
(Homo
sapiens)		4 / 7GLU A  56
TRP A  60
ARG A  69
TRP A  70
None
None
SO4  A 300 (-3.8A)
None
0.94A46.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		1kiv APOLIPOPROTEIN A
(Homo
sapiens)		5 / 7ASP A  55
TRP A  62
PHE A  64
ARG A  71
TRP A  72
None
0.99A51.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		2doi ANGIOSTATIN
(Homo
sapiens)		4 / 7TRP X 225
PHE X 227
ARG X 234
TRP X 235
None
1.30A61.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		2doi ANGIOSTATIN
(Homo
sapiens)		6 / 7TYR X 200
ASP X 219
GLU X 221
TRP X 225
PHE X 227
TRP X 235
None
0.94A61.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		2pk4 HUMAN PLASMINOGEN
KRINGLE 4
(Homo
sapiens)		4 / 7ASP A  55
TRP A  62
ARG A  71
TRP A  72
ACA  A 100 ( 2.6A)
ACA  A 100 ( 3.6A)
ACA  A 100 ( 3.6A)
ACA  A 100 ( 3.1A)
0.98A48.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		2pk4 HUMAN PLASMINOGEN
KRINGLE 4
(Homo
sapiens)		4 / 7ASP A  57
TRP A  62
PHE A  64
TRP A  72
ACA  A 100 ( 3.7A)
ACA  A 100 ( 3.6A)
ACA  A 100 ( 4.1A)
ACA  A 100 ( 3.1A)
1.20A48.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		2pk4 HUMAN PLASMINOGEN
KRINGLE 4
(Homo
sapiens)		4 / 7TRP A  62
PHE A  64
ARG A  71
TRP A  72
ACA  A 100 ( 3.6A)
ACA  A 100 ( 4.1A)
ACA  A 100 ( 3.6A)
ACA  A 100 ( 3.1A)
1.08A48.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		3edy TRIPEPTIDYL-PEPTIDAS
E 1
(Homo
sapiens)		4 / 7TYR A 441
ASP A 528
GLU A 529
ARG A 371
None
None
None
EDO  A 703 ( 4.6A)
1.43A8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		3fjo NADPH-CYTOCHROME
P450 REDUCTASE
(Homo
sapiens;
Saccharomyces
cerevisiae)		4 / 7TYR A  75
ASP A 193
GLU A 194
PHE A 150
None
1.48A7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		3l6y CATENIN DELTA-1
(Homo
sapiens)		4 / 7TYR A 650
GLU A 593
PHE A 654
ARG A 599
None
1.26A8.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		4bvw APOLIPOPROTEIN(A)
(Homo
sapiens)		5 / 7ASP A  54
GLU A  56
TRP A  60
ARG A  69
TRP A  70
HKY  A1080 (-3.0A)
HKY  A1080 (-3.8A)
HKY  A1080 (-3.6A)
HKY  A1080 (-3.5A)
HKY  A1080 (-3.5A)
0.78A41.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		4cg4 PYRIN
(Homo
sapiens)		4 / 7ASP A 603
GLU A 605
PHE A 636
ARG A 676
None
1.27A12.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		4duu PLASMINOGEN
(Homo
sapiens)		4 / 7TRP A 417
PHE A 419
ARG A 426
TRP A 427
None
1.11A61.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		4duu PLASMINOGEN
(Homo
sapiens)		6 / 7TYR A 200
ASP A 219
GLU A 221
TRP A 225
PHE A 227
TRP A 235
None
0.69A61.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		4duu PLASMINOGEN
(Homo
sapiens)		6 / 7TYR A 200
GLU A 221
TRP A 225
PHE A 227
ARG A 234
TRP A 235
None
0.79A61.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		4kjv E3 UBIQUITIN-PROTEIN
LIGASE XIAP
(Homo
sapiens)		4 / 7GLU A 183
TRP A 217
PHE A 229
ARG A 166
None
1.39A22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		5jpn COMPLEMENT C4-A
(Homo
sapiens)		4 / 7TYR C1701
ASP C1689
GLU C1624
PHE C1627
None
1.29A19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		5u8q FV 24-60 HEAVY CHAIN
INSULIN-LIKE GROWTH
FACTOR 1 RECEPTOR
(Homo
sapiens;
Mus
musculus)		4 / 7TYR H  54
GLU A  53
PHE A 241
ARG A 245
None
None
None
MLT  A1003 ( 4.8A)
1.47A25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		1gng GLYCOGEN SYNTHASE
KINASE-3 BETA
(Homo
sapiens)		4 / 7ARG A 223
ASP A 264
ASP A 260
TYR A 221
PTR  A 216 ( 2.9A)
None
None
None
1.41A13.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)		1i71 APOLIPOPROTEIN(A)
(Homo
sapiens)		4 / 7ASP A  54
TRP A  60
TYR A  62
ARG A  69
None
None
SO4  A 300 (-4.7A)
SO4  A 300 (-3.8A)
1.07A44.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)		1kiv APOLIPOPROTEIN A
(Homo
sapiens)		4 / 7ASP A  55
ASP A  57
TRP A  62
ARG A  71
None
0.76A54.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)		1pkr PLASMINOGEN
(Homo
sapiens)		6 / 7ARG A  34
ASP A  55
TRP A  62
TYR A  64
ARG A  71
TYR A  72
None
CL  A  91 ( 4.7A)
None
None
CL  A  90 (-3.6A)
None
0.81A98.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)		1pkr PLASMINOGEN
(Homo
sapiens)		6 / 7ASP A  55
ASP A  57
TRP A  62
TYR A  64
ARG A  71
TYR A  72
 CL  A  91 ( 4.7A)
None
None
None
CL  A  90 (-3.6A)
None
0.63A98.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		1rkb PROTEIN AD-004
(Homo
sapiens)		4 / 7ARG A  70
ASP A  63
ASP A  59
ARG A  87
None
None
LI  A 303 ( 4.6A)
None
1.49A16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT
(Homo
sapiens)		4 / 7ASP A 573
TRP A 519
TYR A 418
ARG A 421
None
1.29A7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens)		4 / 7ASP A 510
ASP A 157
TYR A 110
ARG A 111
None
1.18A8.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)		2doi ANGIOSTATIN
(Homo
sapiens)		6 / 7ASP X 137
ASP X 139
TRP X 144
TYR X 146
ARG X 153
TYR X 154
None
0.59A100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)		2hpq PROTHROMBIN
(Homo
sapiens)		4 / 7ASP P 354
ASP P 356
TRP P 361
TYR P 363
None
0.80A35.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)		2pk4 HUMAN PLASMINOGEN
KRINGLE 4
(Homo
sapiens)		4 / 7ASP A  55
ASP A  57
TRP A  62
ARG A  71
ACA  A 100 ( 2.6A)
ACA  A 100 ( 3.7A)
ACA  A 100 ( 3.6A)
ACA  A 100 ( 3.6A)
0.57A51.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		2vc2 INTEGRIN ALPHA-IIB
(Homo
sapiens)		4 / 7ARG A 400
ASP A 373
ASP A 365
TYR A 371
None
CA  A2006 (-2.4A)
CA  A2006 (-3.4A)
None
1.29A9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		3e6p PROTHROMBIN
(Homo
sapiens)		4 / 7ASP L 223
ASP L 225
TRP L 230
TYR L 232
None
0.46A22.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)		3k65 PROTHROMBIN
(Homo
sapiens)		4 / 7ASP A 223
ASP A 225
TRP A 230
TYR A 232
None
0.38A31.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		3nxp PRETHROMBIN-1
(Homo
sapiens)		4 / 7ASP A 223
ASP A 225
TRP A 230
TYR A 232
None
0.48A11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		3ojy COMPLEMENT COMPONENT
C8 ALPHA CHAIN
COMPLEMENT COMPONENT
C8 BETA CHAIN
(Homo
sapiens)		4 / 7ASP B 113
TRP B 116
TYR B 404
ARG A 156
None
1.34A9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		4boc DNA-DIRECTED RNA
POLYMERASE,
MITOCHONDRIAL
(Homo
sapiens)		4 / 7ARG A 803
ASP A1128
ASP A1151
TYR A 807
None
None
C  R   9 ( 2.8A)
None
1.39A7.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)		4bvv APOLIPOPROTEIN(A)
(Homo
sapiens)		4 / 7ASP A  55
ASP A  57
TRP A  62
TYR A  64
CPF  A1081 (-3.1A)
CPF  A1081 (-3.9A)
CPF  A1081 (-3.6A)
CPF  A1081 (-4.8A)
0.40A53.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)		4bvw APOLIPOPROTEIN(A)
(Homo
sapiens)		4 / 7ASP A  54
TRP A  60
TYR A  62
ARG A  69
HKY  A1080 (-3.0A)
HKY  A1080 (-3.6A)
HKY  A1080 (-4.6A)
HKY  A1080 (-3.5A)
0.64A44.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)		4duu PLASMINOGEN
(Homo
sapiens)		6 / 7ASP A 137
ASP A 139
TRP A 144
TYR A 146
ARG A 153
TYR A 154
None
0.83A100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)		4duu PLASMINOGEN
(Homo
sapiens)		4 / 7ASP A 516
ASP A 518
TRP A 523
TYR A 525
None
0.78A100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)		4duu PLASMINOGEN
(Homo
sapiens)		4 / 7ASP A 516
TRP A 523
TYR A 525
TYR A 533
None
0.64A100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		4hzh PROTHROMBIN
(Homo
sapiens)		4 / 7ASP A 223
ASP A 225
TRP A 230
TYR A 232
None
0.61A10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		4nzm INOSITOL
HEXAKISPHOSPHATE AND
DIPHOSPHOINOSITOL-PE
NTAKISPHOSPHATE
KINASE 2
(Homo
sapiens)		4 / 7ARG A 262
ASP A 309
ASP A 321
TYR A 250
0EJ  A 402 (-3.0A)
MG  A 404 ( 2.9A)
MG  A 403 (-2.0A)
None
1.11A11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		5fws KREMEN PROTEIN 1
(Homo
sapiens)		4 / 7ASP A  88
ASP A  90
TRP A  94
TYR A  96
None
0.64A11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		5fww KREMEN PROTEIN 1
(Homo
sapiens)		4 / 7ASP B  88
ASP B  90
TRP B  94
TYR B  96
None
0.65A19.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)		5hpg PLASMINOGEN
(Homo
sapiens)		4 / 7ASP A  57
TRP A  62
TYR A  64
TYR A  72
None
0.72A54.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens)		4 / 7ASP A 199
ASP A  39
TYR A  45
ARG A  42
 ZN  A 502 (-2.3A)
ZN  A 501 (-2.0A)
None
None
1.45A13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens)		4 / 7ASP A 191
ASP A  36
TYR A  42
ARG A  39
 ZN  A 502 (-2.0A)
ZN  A 501 (-2.0A)
None
None
1.40A14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		5wde KINESIN-LIKE PROTEIN
KIFC3
(Homo
sapiens)		4 / 7ARG A 665
ASP A 659
ASP A 565
TRP A 566
None
1.36A11.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_B_AMHB90_1
(PLASMINOGEN)		1i71 APOLIPOPROTEIN(A)
(Homo
sapiens)		4 / 7ASP A  54
TRP A  60
TYR A  62
ARG A  69
None
None
SO4  A 300 (-4.7A)
SO4  A 300 (-3.8A)
1.02A44.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_B_AMHB90_1
(PLASMINOGEN)		1kiv APOLIPOPROTEIN A
(Homo
sapiens)		4 / 7ASP A  55
ASP A  57
TRP A  62
ARG A  71
None
0.55A54.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_B_AMHB90_1
(PLASMINOGEN)		1pkr PLASMINOGEN
(Homo
sapiens)		6 / 7ASP A  55
ASP A  57
TRP A  62
TYR A  64
ARG A  71
TYR A  72
 CL  A  91 ( 4.7A)
None
None
None
CL  A  90 (-3.6A)
None
0.61A98.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens)		4 / 7ASP A 510
ASP A 157
TYR A 110
ARG A 111
None
1.14A8.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_B_AMHB90_1
(PLASMINOGEN)		2doi ANGIOSTATIN
(Homo
sapiens)		6 / 7ASP X 137
ASP X 139
TRP X 144
TYR X 146
ARG X 153
TYR X 154
None
0.60A100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_B_AMHB90_1
(PLASMINOGEN)		2pk4 HUMAN PLASMINOGEN
KRINGLE 4
(Homo
sapiens)		4 / 7ASP A  55
ASP A  57
TRP A  62
ARG A  71
ACA  A 100 ( 2.6A)
ACA  A 100 ( 3.7A)
ACA  A 100 ( 3.6A)
ACA  A 100 ( 3.6A)
0.53A51.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		3e6p PROTHROMBIN
(Homo
sapiens)		4 / 7ASP L 223
ASP L 225
TRP L 230
TYR L 232
None
0.33A22.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_B_AMHB90_1
(PLASMINOGEN)		3k65 PROTHROMBIN
(Homo
sapiens)		4 / 7ASP A 223
ASP A 225
TRP A 230
TYR A 232
None
0.40A31.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		3nxp PRETHROMBIN-1
(Homo
sapiens)		4 / 7ASP A 223
ASP A 225
TRP A 230
TYR A 232
None
0.50A11.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_B_AMHB90_1
(PLASMINOGEN)		4bvv APOLIPOPROTEIN(A)
(Homo
sapiens)		4 / 7ASP A  55
ASP A  57
TRP A  62
TYR A  64
CPF  A1081 (-3.1A)
CPF  A1081 (-3.9A)
CPF  A1081 (-3.6A)
CPF  A1081 (-4.8A)
0.47A53.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_B_AMHB90_1
(PLASMINOGEN)		4bvw APOLIPOPROTEIN(A)
(Homo
sapiens)		4 / 7ASP A  54
TRP A  60
TYR A  62
ARG A  69
HKY  A1080 (-3.0A)
HKY  A1080 (-3.6A)
HKY  A1080 (-4.6A)
HKY  A1080 (-3.5A)
0.58A44.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_B_AMHB90_1
(PLASMINOGEN)		4duu PLASMINOGEN
(Homo
sapiens)		6 / 7ASP A 137
ASP A 139
TRP A 144
TYR A 146
ARG A 153
TYR A 154
None
0.82A100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_B_AMHB90_1
(PLASMINOGEN)		4duu PLASMINOGEN
(Homo
sapiens)		5 / 7ASP A 516
ASP A 518
TRP A 523
TYR A 525
TYR A 533
None
0.74A100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		4hzh PROTHROMBIN
(Homo
sapiens)		4 / 7ASP A 223
ASP A 225
TRP A 230
TYR A 232
None
0.36A10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		5fws KREMEN PROTEIN 1
(Homo
sapiens)		4 / 7ASP A  88
ASP A  90
TRP A  94
TYR A  96
None
0.57A11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		5fww KREMEN PROTEIN 1
(Homo
sapiens)		4 / 7ASP B  88
ASP B  90
TRP B  94
TYR B  96
None
0.76A19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		5kj2 HISTONE
ACETYLTRANSFERASE
P300
(Homo
sapiens)		4 / 7ASP A1614
ASP A1616
TYR A1421
TYR A1424
None
1.44A13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		5lkz HISTONE
ACETYLTRANSFERASE
P300,HISTONE
ACETYLTRANSFERASE
P300
(Homo
sapiens)		4 / 7ASP A1614
ASP A1616
TYR A1421
TYR A1424
None
1.46A10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		5udy ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 7
(Homo
sapiens)		4 / 7ASP A 199
ASP A  39
TYR A  45
ARG A  42
 ZN  A 502 (-2.3A)
ZN  A 501 (-2.0A)
None
None
1.39A13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens)		4 / 7ASP A 191
ASP A  36
TYR A  42
ARG A  39
 ZN  A 502 (-2.0A)
ZN  A 501 (-2.0A)
None
None
1.35A14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V3C_A_AMHA402_1
(QUEUINE
TRNA-RIBOSYLTRANSFER
ASE)		1wl4 ACETYL-COENZYME A
ACETYLTRANSFERASE 2
(Homo
sapiens)		5 / 9CYH A 383
GLY A 296
GLY A 294
ALA A 330
VAL A 327
COA  A1001 ( 4.6A)
None
None
None
None
1.29A12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V3C_A_AMHA402_1
(QUEUINE
TRNA-RIBOSYLTRANSFER
ASE)		5o6c E3 UBIQUITIN-PROTEIN
LIGASE MYCBP2
(Homo
sapiens)		5 / 9TYR A4513
GLY A4516
GLY A4515
ALA A4568
VAL A4569
None
1.34A21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V3C_A_AMHA402_1
(QUEUINE
TRNA-RIBOSYLTRANSFER
ASE)		5v1b EGL NINE HOMOLOG 2
(Homo
sapiens)		5 / 9CYH A 250
GLY A 254
GLY A 245
ALA A 282
VAL A 243
None
1.44A20.25