POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_1 (GLUCOCORTICOID RECEPTOR)	2ax9	ANDROGEN RECEPTOR (Homo sapiens)	5 / 12	ARG A 752 MET A 780 GLN A 783 CYH A 784 MET A 787	BHM  A   1 (-3.8A) BHM  A   1 ( 4.3A) None None BHM  A   1 (-3.6A)	1.14A	46.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_1 (GLUCOCORTICOID RECEPTOR)	2ax9	ANDROGEN RECEPTOR (Homo sapiens)	5 / 12	ASN A 705 GLY A 708 GLN A 711 CYH A 784 PHE A 891	BHM  A   1 (-3.6A) BHM  A   1 ( 3.8A) BHM  A   1 (-2.2A) None None	0.92A	46.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_1 (GLUCOCORTICOID RECEPTOR)	2ax9	ANDROGEN RECEPTOR (Homo sapiens)	6 / 12	ASN A 705 GLY A 708 GLN A 711 MET A 742 ARG A 752 CYH A 784	BHM  A   1 (-3.6A) BHM  A   1 ( 3.8A) BHM  A   1 (-2.2A) BHM  A   1 ( 4.0A) BHM  A   1 (-3.8A) None	0.77A	46.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_1 (GLUCOCORTICOID RECEPTOR)	2ax9	ANDROGEN RECEPTOR (Homo sapiens)	6 / 12	GLY A 708 GLN A 711 ARG A 752 GLN A 783 CYH A 784 MET A 787	BHM  A   1 ( 3.8A) BHM  A   1 (-2.2A) BHM  A   1 (-3.8A) None None BHM  A   1 (-3.6A)	1.23A	46.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_1 (GLUCOCORTICOID RECEPTOR)	2ax9	ANDROGEN RECEPTOR (Homo sapiens)	6 / 12	GLY A 708 GLN A 711 MET A 742 ARG A 752 CYH A 784 MET A 787	BHM  A   1 ( 3.8A) BHM  A   1 (-2.2A) BHM  A   1 ( 4.0A) BHM  A   1 (-3.8A) None BHM  A   1 (-3.6A)	0.83A	46.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_1 (GLUCOCORTICOID RECEPTOR)	3kba	PROGESTERONE RECEPTOR (Homo sapiens)	8 / 12	ASN A 719 GLY A 722 MET A 756 ARG A 766 CYH A 798 MET A 801 THR A 894 PHE A 905	WOW  A   1 (-3.3A) WOW  A   1 ( 4.3A) WOW  A   1 ( 4.1A) WOW  A   1 (-3.8A) WOW  A   1 ( 4.1A) WOW  A   1 (-4.2A) WOW  A   1 (-3.9A) WOW  A   1 (-4.6A)	0.72A	49.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_1 (GLUCOCORTICOID RECEPTOR)	3kba	PROGESTERONE RECEPTOR (Homo sapiens)	6 / 12	GLY A 722 GLN A 725 MET A 756 ARG A 766 CYH A 798 MET A 801	WOW  A   1 ( 4.3A) WOW  A   1 ( 4.1A) WOW  A   1 ( 4.1A) WOW  A   1 (-3.8A) WOW  A   1 ( 4.1A) WOW  A   1 (-4.2A)	0.87A	49.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_1 (GLUCOCORTICOID RECEPTOR)	4p6w	GLUCOCORTICOID RECEPTOR (Homo sapiens)	6 / 12	ASN A 564 GLY A 568 GLN A 570 MET A 601 THR A 739 PHE A 749	MOF  A 801 (-3.0A) None MOF  A 801 (-2.9A) MOF  A 801 (-3.7A) MOF  A 801 (-3.9A) MOF  A 801 (-4.4A)	1.20A	96.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_1 (GLUCOCORTICOID RECEPTOR)	4p6w	GLUCOCORTICOID RECEPTOR (Homo sapiens)	7 / 12	GLN A 570 MET A 601 ARG A 611 GLN A 642 CYH A 643 MET A 646 THR A 739	MOF  A 801 (-2.9A) MOF  A 801 (-3.7A) MOF  A 801 (-4.2A) None MOF  A 801 ( 3.7A) MOF  A 801 (-4.4A) MOF  A 801 (-3.9A)	1.11A	96.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_1 (GLUCOCORTICOID RECEPTOR)	4p6w	GLUCOCORTICOID RECEPTOR (Homo sapiens)	11 / 12	MET A 560 ASN A 564 GLY A 567 GLN A 570 MET A 601 ARG A 611 MET A 639 CYH A 643 MET A 646 THR A 739 PHE A 749	MOF  A 801 (-3.9A) MOF  A 801 (-3.0A) MOF  A 801 (-3.4A) MOF  A 801 (-2.9A) MOF  A 801 (-3.7A) MOF  A 801 (-4.2A) MOF  A 801 (-3.7A) MOF  A 801 ( 3.7A) MOF  A 801 (-4.4A) MOF  A 801 (-3.9A) MOF  A 801 (-4.4A)	0.61A	96.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_1 (GLUCOCORTICOID RECEPTOR)	4udb	MINERALOCORTICOID RECEPTOR (Homo sapiens)	7 / 12	ASN A 770 GLN A 776 MET A 807 ARG A 817 CYH A 849 MET A 852 THR A 945	CV7  A1987 (-3.1A) CV7  A1987 (-3.0A) CV7  A1987 ( 3.9A) CV7  A1987 (-3.7A) CV7  A1987 ( 4.2A) CV7  A1987 ( 3.7A) CV7  A1987 (-3.1A)	0.55A	51.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_1 (GLUCOCORTICOID RECEPTOR)	4udb	MINERALOCORTICOID RECEPTOR (Homo sapiens)	7 / 12	ASN A 770 GLN A 776 MET A 807 ARG A 817 MET A 852 THR A 945 PHE A 956	CV7  A1987 (-3.1A) CV7  A1987 (-3.0A) CV7  A1987 ( 3.9A) CV7  A1987 (-3.7A) CV7  A1987 ( 3.7A) CV7  A1987 (-3.1A) CV7  A1987 ( 4.7A)	0.57A	51.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_1 (GLUCOCORTICOID RECEPTOR)	4udb	MINERALOCORTICOID RECEPTOR (Homo sapiens)	5 / 12	ASN A 770 GLY A 774 GLN A 776 THR A 945 PHE A 956	CV7  A1987 (-3.1A) None CV7  A1987 (-3.0A) CV7  A1987 (-3.1A) CV7  A1987 ( 4.7A)	1.32A	51.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_1 (GLUCOCORTICOID RECEPTOR)	4udb	MINERALOCORTICOID RECEPTOR (Homo sapiens)	5 / 12	GLN A 776 ARG A 817 MET A 840 CYH A 849 MET A 852	CV7  A1987 (-3.0A) CV7  A1987 (-3.7A) CV7  A1987 ( 3.7A) CV7  A1987 ( 4.2A) CV7  A1987 ( 3.7A)	0.91A	51.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_1 (GLUCOCORTICOID RECEPTOR)	5mwp	MINERALOCORTICOID RECEPTOR (Homo sapiens)	7 / 12	ASN A 770 GLN A 776 MET A 807 ARG A 817 CYH A 849 THR A 945 PHE A 956	ECV  A1101 (-3.1A) ECV  A1101 (-2.9A) ECV  A1101 (-3.6A) ECV  A1101 (-4.0A) ECV  A1101 (-3.8A) ECV  A1101 (-3.2A) ECV  A1101 ( 4.7A)	0.59A	42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_1 (GLUCOCORTICOID RECEPTOR)	5mwp	MINERALOCORTICOID RECEPTOR (Homo sapiens)	5 / 12	ASN A 770 GLY A 774 GLN A 776 THR A 945 PHE A 956	ECV  A1101 (-3.1A) None ECV  A1101 (-2.9A) ECV  A1101 (-3.2A) ECV  A1101 ( 4.7A)	1.26A	42.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_1 (GLUCOCORTICOID RECEPTOR)	5mwp	MINERALOCORTICOID RECEPTOR (Homo sapiens)	5 / 12	GLN A 776 MET A 807 ARG A 817 CYH A 849 MET A 852	ECV  A1101 (-2.9A) ECV  A1101 (-3.6A) ECV  A1101 (-4.0A) ECV  A1101 (-3.8A) ECV  A1101 (-3.7A)	1.22A	42.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	1ewi	REPLICATION PROTEIN A (Homo sapiens)	4 / 4	LEU A  50 MET A  14 ILE A  28 LEU A  53	None	1.31A	18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	2oq5	TRANSMEMBRANE PROTEASE, SERINE 11E (Homo sapiens)	4 / 4	LEU A 209 MET A 136 ILE A 103 LEU A 181	None	1.41A	20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	2vfk	AKAP18 DELTA (Homo sapiens)	4 / 4	LEU A 248 MET A 125 ILE A 253 LEU A 110	None	1.40A	21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	2xwu	IMPORTIN13 (Homo sapiens)	4 / 4	LEU B 130 MET B 135 ILE B 109 LEU B 173	None	1.12A	15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	3b2r	CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE (Homo sapiens)	4 / 4	LEU A 646 MET A 578 ILE A 716 LEU A 651	None	1.30A	24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	3bjc	CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE (Homo sapiens)	4 / 4	LEU A 646 MET A 578 ILE A 716 LEU A 651	None	1.35A	15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	3c5w	PP2A A SUBUNIT (Homo sapiens)	4 / 4	LEU A 411 MET A 427 ILE A  17 LEU A 405	None	1.28A	20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	3nzu	PHOSPHATIDYLINOSITOL -4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM (Homo sapiens)	4 / 4	LEU A1030 MET A 851 ILE A1048 LEU A 942	None	1.33A	13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	3sag	EXOSOME COMPONENT 10 (Homo sapiens)	4 / 4	LEU A 544 MET A 579 ILE A 551 LEU A 512	LEU  A 544 ( 0.6A) MET  A 579 ( 0.0A) ILE  A 551 ( 0.7A) LEU  A 512 ( 0.6A)	1.40A	22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	4bkx	HISTONE DEACETYLASE 1 (Homo sapiens)	4 / 4	LEU B 293 MET B 245 ILE B 131 LEU B 259	None	1.31A	17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	4oiv	BILE ACID RECEPTOR (Homo sapiens)	4 / 4	LEU A 388 MET A 381 ILE A 394 LEU A 334	None	1.41A	24.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	4p6w	GLUCOCORTICOID RECEPTOR (Homo sapiens)	4 / 4	LEU A 563 MET A 604 ILE A 747 LEU A 753	MOF  A 801 (-3.9A) None MOF  A 801 ( 4.4A) None	0.38A	96.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	4pj3	INTRON-BINDING PROTEIN AQUARIUS (Homo sapiens)	4 / 4	LEU A1227 MET A1294 ILE A1237 LEU A1275	None	1.33A	10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	4ykn	PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA,PHOSPHATIDYLIN OSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM FUSION PROTEIN (Homo sapiens)	4 / 4	LEU A2001 MET A1820 ILE A2019 LEU A1911	None	1.14A	11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	5kc8	GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2 (Homo sapiens)	4 / 4	LEU A 144 MET A 369 ILE A 119 LEU A 334	None	1.37A	21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	5kca	CEREBELLIN-1,CEREBEL LIN-1,CEREBELLIN-1,G LUTAMATE RECEPTOR IONOTROPIC, DELTA-2 (Homo sapiens)	4 / 4	LEU A 630 MET A 855 ILE A 605 LEU A 820	None	1.41A	14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	5kkp	PSEUDOURIDYLATE SYNTHASE 7 (Homo sapiens)	4 / 4	LEU A 531 MET A 487 ILE A 476 LEU A 551	None	1.28A	19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	5w4b	ADENOSYLHOMOCYSTEINA SE (Homo sapiens)	4 / 4	LEU A  63 MET A  29 ILE A  97 LEU A  22	None	1.40A	20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	5xgj	PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM (Homo sapiens)	4 / 4	LEU A1001 MET A 820 ILE A1019 LEU A 911	None	1.28A	15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	6b5c	KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 1 (Homo sapiens)	4 / 4	LEU A 355 MET A 336 ILE A 376 LEU A 372	None	1.27A	13.96