POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EFJ_A_37TA502_1 (3,7-DIMETHYLXANTHINE METHYLTRANSFERASE)	1zkc	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE LIKE 2 (Homo sapiens)	5 / 12	TYR A 316 LEU A 366 ILE A 330 ILE A 426 ILE A 428	None	1.36A	19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EFJ_A_37TA502_1 (3,7-DIMETHYLXANTHINE METHYLTRANSFERASE)	1zrz	PROTEIN KINASE C, IOTA (Homo sapiens)	5 / 12	LEU A 372 TYR A 410 TRP A 428 SER A 442 ILE A 465	None	1.34A	23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EFJ_A_37TA502_1 (3,7-DIMETHYLXANTHINE METHYLTRANSFERASE)	4bn2	KINESIN-LIKE PROTEIN KIF15 (Homo sapiens)	5 / 12	LEU A 278 ILE A 322 ILE A  13 ILE A 285 TYR A  94	None	1.39A	21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EFJ_A_37TA502_1 (3,7-DIMETHYLXANTHINE METHYLTRANSFERASE)	4d86	POLY [ADP-RIBOSE] POLYMERASE 14 (Homo sapiens)	5 / 12	LEU A 859 ILE A 921 SER A 904 ILE A 918 ILE A 878	None	1.30A	21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EFJ_A_37TA502_1 (3,7-DIMETHYLXANTHINE METHYLTRANSFERASE)	4k3j	HEPATOCYTE GROWTH FACTOR BETA CHAIN (Homo sapiens)	5 / 12	LEU B 238 ILE B 247 ILE B 279 ILE B 235 TYR B 291	None	1.46A	21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EFJ_A_37TA502_1 (3,7-DIMETHYLXANTHINE METHYLTRANSFERASE)	5knm	LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY B MEMBER 1 (Homo sapiens)	5 / 12	HIS D  69 TRP D  46 ILE D  65 ILE D  62 TYR D  73	None	1.45A	23.14