POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DIT_P_2PPP1_1 (ALPHA-THROMBIN PEPTIDE INHIBITOR CVS995)	1l1f	GLUTAMATE DEHYDROGENASE 1 (Homo sapiens)	4 / 6	LEU A 145 ILE A  69 GLU A  77 PRO A 137	None	1.22A	19.52 3.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DIT_P_2PPP1_1 (ALPHA-THROMBIN PEPTIDE INHIBITOR CVS995)	2ctf	VIGILIN (Homo sapiens)	4 / 6	LEU A  37 GLU A  65 ASP A  68 PRO A  34	None	1.02A	17.05 8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DIT_P_2PPP1_1 (ALPHA-THROMBIN PEPTIDE INHIBITOR CVS995)	2dag	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 5 (Homo sapiens)	4 / 6	LEU A  16 ILE A  14 GLU A  10 ASP A   9	None	1.12A	14.67 12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DIT_P_2PPP1_1 (ALPHA-THROMBIN PEPTIDE INHIBITOR CVS995)	2dit	HIV TAT SPECIFIC FACTOR 1 VARIANT (Homo sapiens)	4 / 6	LEU A  58 ILE A  20 GLU A  46 ASP A  42	None	1.14A	20.61 23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DIT_P_2PPP1_1 (ALPHA-THROMBIN PEPTIDE INHIBITOR CVS995)	2f37	TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 2 (Homo sapiens)	4 / 6	LEU A 167 ILE A 169 GLU A 172 PRO A 212	None	1.21A	21.19 7.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DIT_P_2PPP1_1 (ALPHA-THROMBIN PEPTIDE INHIBITOR CVS995)	3r3g	THROMBIN HEAVY CHAIN (Homo sapiens)	4 / 6	LEU B  99 ILE B 174 TRP B 215 GLU B 217	None	0.58A	97.68 4.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DIT_P_2PPP1_1 (ALPHA-THROMBIN PEPTIDE INHIBITOR CVS995)	3s5n	4-HYDROXY-2-OXOGLUTA RATE ALDOLASE, MITOCHONDRIAL (Homo sapiens)	4 / 6	LEU A 242 ILE A 291 ASP A 320 PRO A 275	None	1.22A	20.13 4.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DIT_P_2PPP1_1 (ALPHA-THROMBIN PEPTIDE INHIBITOR CVS995)	4a4l	SERINE/THREONINE-PRO TEIN KINASE PLK1 (Homo sapiens)	4 / 6	LEU A 314 ILE A 316 GLU A 186 ASP A 187	None	1.19A	19.94 7.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DIT_P_2PPP1_1 (ALPHA-THROMBIN PEPTIDE INHIBITOR CVS995)	4iqh	DYSFERLIN (Homo sapiens)	4 / 6	LEU A  83 GLU A  75 ASP A  23 PRO A  24	None	1.16A	21.81 6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DIT_P_2PPP1_1 (ALPHA-THROMBIN PEPTIDE INHIBITOR CVS995)	4obs	ALPHA-L-IDURONIDASE (Homo sapiens)	4 / 6	LEU A 476 GLU A 508 ASP A 509 PRO A 510	None	1.21A	16.98 2.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DIT_P_2PPP1_1 (ALPHA-THROMBIN PEPTIDE INHIBITOR CVS995)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	4 / 6	LEU B 294 ILE B 297 ASP B 274 PRO B 277	None	1.23A	22.53 5.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DIT_P_2PPP1_1 (ALPHA-THROMBIN PEPTIDE INHIBITOR CVS995)	5ons	DENSITY-REGULATED PROTEIN MALIGNANT T-CELL-AMPLIFIED SEQUENCE 1 (Homo sapiens)	4 / 6	LEU A 170 ILE A 102 GLU B  45 PRO B  40	None	0.99A	14.46 23.53