POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V3Q_E_2DIE290_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	2wl1	PYRIN (Homo sapiens)	5 / 10	VAL A 659 GLY A 660 THR A 735 ASN A 733 VAL A 718	None	1.32A	20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V3Q_E_2DIE290_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	2wpm	COAGULATION FACTOR IXA HEAVY CHAIN (Homo sapiens)	5 / 10	GLY S  43 PHE S  41 GLY S 193 THR S  54 VAL S  32	None	1.25A	21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V3Q_E_2DIE290_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	3pm0	CYTOCHROME P450 1B1 (Homo sapiens)	5 / 10	VAL A 235 GLY A 232 ASN A 265 VAL A 126 HIS A 227	None	1.32A	20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V3Q_E_2DIE290_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	3thc	BETA-GALACTOSIDASE (Homo sapiens)	5 / 10	GLY A 494 VAL A 439 GLY A 438 THR A 405 VAL A 477	None	1.13A	17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V3Q_E_2DIE290_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	5k5f	HELICASE-LIKE TRANSCRIPTION FACTOR (Homo sapiens)	5 / 10	VAL A  83 GLY A 132 MET A 148 ASN A 139 HIS A  66	None	1.22A	18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V3Q_E_2DIE290_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	5k5f	HELICASE-LIKE TRANSCRIPTION FACTOR (Homo sapiens)	5 / 10	VAL A  83 GLY A 132 MET A 148 VAL A 108 HIS A  66	None	1.28A	18.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1V3Q_E_2DIE290_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	5ugf	PURINE NUCLEOSIDE PHOSPHORYLASE (Homo sapiens)	10 / 10	GLY A 118 PHE A 200 GLU A 201 VAL A 217 GLY A 218 MET A 219 THR A 242 ASN A 243 VAL A 245 HIS A 257	IM5  A 308 (-3.7A) IM5  A 308 (-4.6A) IM5  A 308 (-2.9A) IM5  A 308 (-4.4A) IM5  A 308 (-3.4A) IM5  A 308 (-3.5A) IM5  A 308 (-4.3A) IM5  A 308 (-3.1A) IM5  A 308 ( 4.5A) IM5  A 308 (-3.6A)	0.43A	99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1V3Q_E_2DIE290_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	5ugf	PURINE NUCLEOSIDE PHOSPHORYLASE (Homo sapiens)	5 / 10	GLY A 119 GLU A 201 VAL A 217 ASN A 243 VAL A 245	None IM5  A 308 (-2.9A) IM5  A 308 (-4.4A) IM5  A 308 (-3.1A) IM5  A 308 ( 4.5A)	1.32A	99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1V3Q_E_2DIE290_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	5ugf	PURINE NUCLEOSIDE PHOSPHORYLASE (Homo sapiens)	5 / 10	GLY A 218 PHE A 200 GLU A 201 GLY A 197 HIS A 257	IM5  A 308 (-3.4A) IM5  A 308 (-4.6A) IM5  A 308 (-2.9A) None IM5  A 308 (-3.6A)	1.24A	99.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1V3Q_E_2DIE290_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	5ugf	PURINE NUCLEOSIDE PHOSPHORYLASE (Homo sapiens)	5 / 10	PHE A 200 GLU A 201 VAL A 245 GLY A 118 HIS A 257	IM5  A 308 (-4.6A) IM5  A 308 (-2.9A) IM5  A 308 ( 4.5A) IM5  A 308 (-3.7A) IM5  A 308 (-3.6A)	1.11A	99.65