KNOWN TARGETS FROM HUMAN (PROTEIN-DRUG COMPLEXES IN THE PDB)

1) Click on the entry ID to view details of interfaces and pattern clusters
2) Note that ASSAM search use only 3-12 residue containing patterns
DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM View
6DLZ_A_CYZA1302 6dlz CYZ

DB00606
(Cyclothiazide)		 Homo sapiens;
Rattus
norvegicus		 GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT		 None
PF00060
(PMP22_Claudin)
PF00822
(Lig_chan)
PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd)		 10 ILE D 481
PRO A 494
MET A 496
SER A 497
SER D 729
GLY D 731
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ A1302
6DLZ_B_CYZB1302 6dlz CYZ

DB00606
(Cyclothiazide)		 Homo sapiens;
Rattus
norvegicus		 GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT		 None 10 ILE C 481
PRO C 494
MET B 496
SER B 497
SER C 729
LEU B 751
SER B 754
LEU B 759
ASP B 760
LYS B 763
 CYZ B1302
6DLZ_C_CYZC1302 6dlz CYZ

DB00606
(Cyclothiazide)		 Homo sapiens;
Rattus
norvegicus		 GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT		 None 10 ILE B 481
PRO C 494
MET C 496
SER C 497
SER B 729
GLY B 731
LEU C 751
SER C 754
ASP C 760
LYS C 763
 CYZ C1302
6DLZ_D_CYZD1302 6dlz CYZ

DB00606
(Cyclothiazide)		 Homo sapiens;
Rattus
norvegicus		 GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT		 None
PF00060
(PMP22_Claudin)
PF00822
(Lig_chan)
PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd)		 11 ILE A 481
PRO A 494
PRO D 494
MET D 496
SER D 497
SER A 729
LEU D 751
SER D 754
LEU D 759
ASP D 760
LYS D 763
 CYZ D1302
6DM0_A_CYZA1302 6dm0 CYZ

DB00606
(Cyclothiazide)		 Homo sapiens;
Rattus
norvegicus		 GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT		 None
PF00060
(PMP22_Claudin)
PF00822
(Lig_chan-Glu_bd)
PF01094
(Lig_chan)
PF10613
(ANF_receptor)		 9 ILE D 481
PRO A 494
MET A 496
SER A 497
SER D 729
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ A1302
6DM0_B_CYZB1302 6dm0 CYZ

DB00606
(Cyclothiazide)		 Homo sapiens;
Rattus
norvegicus		 GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT		 None 10 ILE C 481
PRO C 494
MET B 496
SER B 497
SER C 729
GLY C 731
LEU B 751
LEU B 759
ASP B 760
LYS B 763
 CYZ B1302
6DM0_C_CYZC1302 6dm0 CYZ

DB00606
(Cyclothiazide)		 Homo sapiens;
Rattus
norvegicus		 GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT		 None 9 ILE B 481
PRO C 494
MET C 496
SER C 497
SER B 729
LEU C 751
SER C 754
ASP C 760
LYS C 763
 CYZ C1302
6DM0_D_CYZD1302 6dm0 CYZ

DB00606
(Cyclothiazide)		 Homo sapiens;
Rattus
norvegicus		 GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT		 None
PF00060
(PMP22_Claudin)
PF00822
(Lig_chan-Glu_bd)
PF01094
(Lig_chan)
PF10613
(ANF_receptor)		 9 PRO A 494
MET D 496
SER D 497
SER A 729
GLY A 731
LEU D 751
LEU D 759
ASP D 760
LYS D 763
 CYZ D1302
6DM1_A_CYZA1302 6dm1 CYZ

DB00606
(Cyclothiazide)		 Homo sapiens;
Rattus
norvegicus		 GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT		 None
PF00060
(ANF_receptor)
PF00822
(Lig_chan)
PF01094
(Lig_chan-Glu_bd)
PF10613
(PMP22_Claudin)		 10 ILE D 481
PRO A 494
MET A 496
SER A 497
SER D 729
GLY D 731
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ A1302
6DM1_B_CYZB1302 6dm1 CYZ

DB00606
(Cyclothiazide)		 Homo sapiens;
Rattus
norvegicus		 GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT		 None 10 ILE C 481
PRO C 494
MET B 496
SER B 497
SER C 729
LEU B 751
SER B 754
LEU B 759
ASP B 760
LYS B 763
 CYZ B1302
6DM1_C_CYZC1302 6dm1 CYZ

DB00606
(Cyclothiazide)		 Homo sapiens;
Rattus
norvegicus		 GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT		 None 10 ILE B 481
PRO C 494
MET C 496
SER C 497
SER B 729
GLY B 731
LEU C 751
SER C 754
ASP C 760
LYS C 763
 CYZ C1302
6DM1_D_CYZD1302 6dm1 CYZ

DB00606
(Cyclothiazide)		 Homo sapiens;
Rattus
norvegicus		 GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT		 None
PF00060
(ANF_receptor)
PF00822
(Lig_chan)
PF01094
(Lig_chan-Glu_bd)
PF10613
(PMP22_Claudin)		 11 ILE A 481
PRO A 494
PRO D 494
MET D 496
SER D 497
SER A 729
LEU D 751
SER D 754
LEU D 759
ASP D 760
LYS D 763
 CYZ D1302
6DM2_A_CYZA1302 6dm2 CYZ

DB00606
(Cyclothiazide)		 Homo sapiens;
Rattus
norvegicus		 GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT		 None
PF00060
(PMP22_Claudin)
PF00822
(Lig_chan)
PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd)		 9 ILE D 481
PRO A 494
MET A 496
SER A 497
SER D 729
LEU A 751
SER A 754
ASP A 760
LYS A 763
 CYZ A1302
6DM2_B_CYZB1302 6dm2 CYZ

DB00606
(Cyclothiazide)		 Homo sapiens;
Rattus
norvegicus		 GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT		 None 10 ILE C 481
PRO C 494
MET B 496
SER B 497
SER C 729
LEU B 751
SER B 754
LEU B 759
ASP B 760
LYS B 763
 CYZ B1302
6DM2_C_CYZC1302 6dm2 CYZ

DB00606
(Cyclothiazide)		 Homo sapiens;
Rattus
norvegicus		 GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT		 None 9 ILE B 481
PRO C 494
MET C 496
SER C 497
SER B 729
LEU C 751
SER C 754
ASP C 760
LYS C 763
 CYZ C1302
6DM2_D_CYZD1302 6dm2 CYZ

DB00606
(Cyclothiazide)		 Homo sapiens;
Rattus
norvegicus		 GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT		 None
PF00060
(PMP22_Claudin)
PF00822
(Lig_chan)
PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd)		 10 ILE A 481
PRO A 494
MET D 496
SER D 497
SER A 729
LEU D 751
SER D 754
LEU D 759
ASP D 760
LYS D 763
 CYZ D1302